ES2252509T3 - Compuestos de aminopirrol como agentes antiinflamatorios. - Google Patents

Compuestos de aminopirrol como agentes antiinflamatorios.

Info

Publication number
ES2252509T3
ES2252509T3 ES02767427T ES02767427T ES2252509T3 ES 2252509 T3 ES2252509 T3 ES 2252509T3 ES 02767427 T ES02767427 T ES 02767427T ES 02767427 T ES02767427 T ES 02767427T ES 2252509 T3 ES2252509 T3 ES 2252509T3
Authority
ES
Spain
Prior art keywords
compound
phenyl
disease
formula
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02767427T
Other languages
English (en)
Spanish (es)
Inventor
David Michael Goldstein
David Mark Rotstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2252509T3 publication Critical patent/ES2252509T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES02767427T 2001-08-30 2002-08-26 Compuestos de aminopirrol como agentes antiinflamatorios. Expired - Lifetime ES2252509T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31616901P 2001-08-30 2001-08-30
US316169P 2001-08-30

Publications (1)

Publication Number Publication Date
ES2252509T3 true ES2252509T3 (es) 2006-05-16

Family

ID=23227809

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02767427T Expired - Lifetime ES2252509T3 (es) 2001-08-30 2002-08-26 Compuestos de aminopirrol como agentes antiinflamatorios.

Country Status (16)

Country Link
US (1) US6696471B2 (https=)
EP (1) EP1423378B1 (https=)
JP (1) JP2005506324A (https=)
KR (1) KR20040029075A (https=)
CN (1) CN1281603C (https=)
AR (1) AR037140A1 (https=)
AT (1) ATE309239T1 (https=)
AU (1) AU2002331179B2 (https=)
BR (1) BR0212077A (https=)
CA (1) CA2458808A1 (https=)
DE (1) DE60207273T2 (https=)
ES (1) ES2252509T3 (https=)
MX (1) MXPA04001810A (https=)
PL (1) PL373115A1 (https=)
RU (1) RU2315045C2 (https=)
WO (1) WO2003020715A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2181704B1 (en) 2002-12-30 2015-05-06 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US20080113016A1 (en) * 2004-07-26 2008-05-15 Gary Steven Firestein Method for Prevention or Treatment of Inflammatory Disease
CA2681420A1 (en) * 2007-03-20 2008-09-25 Cadila Pharmaceuticals Limited P38 inhibitors
WO2017075274A1 (en) 2015-10-27 2017-05-04 Children's Hospital Medical Center Use of mapk inhibitors to reduce loss of hematopoietic stem cells during ex vivo culture and/or genetic manipulation
WO2017151409A1 (en) 2016-02-29 2017-09-08 University Of Florida Research Foundation, Incorporated Chemotherapeutic methods
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2019071147A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5068234A (en) * 1990-02-26 1991-11-26 Sterling Drug Inc. 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
BR9710352A (pt) 1996-07-11 1999-08-17 Pfizer Compostos piridilpirrole
WO1998007425A1 (en) * 1996-08-21 1998-02-26 Smithkline Beecham Corporation Imidazole compounds, compositions and use
US5776954A (en) * 1996-10-30 1998-07-07 Merck & Co., Inc. Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
CA2329065A1 (en) 1998-05-05 1999-11-11 Francisco Xavier Talamas Pyrazole derivatives as p-38 map kinase inhibitors
WO1999058523A1 (en) * 1998-05-14 1999-11-18 G.D. Searle & Co. 1,5-DIARYL SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS

Also Published As

Publication number Publication date
CN1547578A (zh) 2004-11-17
MXPA04001810A (es) 2004-07-08
PL373115A1 (en) 2005-08-08
US6696471B2 (en) 2004-02-24
KR20040029075A (ko) 2004-04-03
DE60207273D1 (de) 2005-12-15
EP1423378A1 (en) 2004-06-02
JP2005506324A (ja) 2005-03-03
DE60207273T2 (de) 2006-07-20
AR037140A1 (es) 2004-10-27
AU2002331179B2 (en) 2008-04-17
CA2458808A1 (en) 2003-03-13
EP1423378B1 (en) 2005-11-09
US20030130319A1 (en) 2003-07-10
BR0212077A (pt) 2004-09-28
WO2003020715A1 (en) 2003-03-13
RU2315045C2 (ru) 2008-01-20
ATE309239T1 (de) 2005-11-15
CN1281603C (zh) 2006-10-25
RU2004109817A (ru) 2005-10-20

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