ES2251803T3 - Utilizacion de los derivados de la somatostatina y/o de los derivados de la fenil-hidrazona. - Google Patents

Utilizacion de los derivados de la somatostatina y/o de los derivados de la fenil-hidrazona.

Info

Publication number
ES2251803T3
ES2251803T3 ES99107392T ES99107392T ES2251803T3 ES 2251803 T3 ES2251803 T3 ES 2251803T3 ES 99107392 T ES99107392 T ES 99107392T ES 99107392 T ES99107392 T ES 99107392T ES 2251803 T3 ES2251803 T3 ES 2251803T3
Authority
ES
Spain
Prior art keywords
group
phenyl
amino
nitro
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99107392T
Other languages
English (en)
Spanish (es)
Inventor
Gyorgy Dr. Keri
Janos Dr. Szolcsanyi
Erika Dr. Pinter
Zsuzsanna Dr. Helyes
Judit Dr. Erchegyi
Aniko Dr. Horvath
Judit Horvath
Istvan Dr. Teplan
Laszlo Dr. Orfi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biostatin Gyogyszerkutato-Fejleszto Kft
Original Assignee
Biostatin Gyogyszerkutato-Fejleszto Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biostatin Gyogyszerkutato-Fejleszto Kft filed Critical Biostatin Gyogyszerkutato-Fejleszto Kft
Application granted granted Critical
Publication of ES2251803T3 publication Critical patent/ES2251803T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES99107392T 1998-04-27 1999-04-23 Utilizacion de los derivados de la somatostatina y/o de los derivados de la fenil-hidrazona. Expired - Lifetime ES2251803T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9800970A HU226567B1 (en) 1998-04-27 1998-04-27 Use of phenylhydrazon derivates for the preparation of medicaments for the inhibition of neurogenic and non-neurogenic inflammations and for the alleviation of pain
HU9800970 1998-04-27

Publications (1)

Publication Number Publication Date
ES2251803T3 true ES2251803T3 (es) 2006-05-01

Family

ID=89996480

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99107392T Expired - Lifetime ES2251803T3 (es) 1998-04-27 1999-04-23 Utilizacion de los derivados de la somatostatina y/o de los derivados de la fenil-hidrazona.

Country Status (10)

Country Link
US (1) US6689813B2 (enExample)
EP (1) EP0952159B1 (enExample)
JP (1) JP2000001439A (enExample)
KR (1) KR19990083438A (enExample)
AT (1) ATE307145T1 (enExample)
CA (1) CA2269995A1 (enExample)
DE (1) DE69927735T2 (enExample)
DK (1) DK0952159T3 (enExample)
ES (1) ES2251803T3 (enExample)
HU (1) HU226567B1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2353072A1 (en) * 1998-12-14 2000-06-22 Palatin Technologies, Inc. Metallopeptide combinatorial libraries and applications
US7049398B1 (en) * 1999-08-12 2006-05-23 Palatin Technologies, Inc. Melanocortin metallopeptide constructs, combinatorial libraries and applications
AU1623801A (en) * 1999-11-19 2001-05-30 Palatin Technologies, Inc. Opioid metallopeptide compositions and methods
US7385025B2 (en) * 2000-12-19 2008-06-10 Palatin Technologies, Inc. Metallopeptide compounds
AU2002238106A1 (en) * 2001-02-13 2002-08-28 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
US20040106548A1 (en) * 2001-09-07 2004-06-03 Schmidt Michelle A Conformationally constrained labeled peptides for imaging and therapy
CA2561560A1 (en) 2004-03-30 2005-10-13 The Regents Of The University Of California Hydrazide-containing cftr inhibitor compounds and uses thereof
WO2008079897A2 (en) 2006-12-22 2008-07-03 The Regents Of The University Of California Macromolecular conjugates of cystic fibrosis transmembrane conductance regulator protein inhibitors and uses thereof
BRPI0809498A2 (pt) 2007-04-02 2014-09-23 Inst Oneworld Health Compostos inibidores de cftr e seus usos
US8207205B2 (en) 2008-04-21 2012-06-26 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
WO2009131951A2 (en) 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
US8343976B2 (en) 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
DE202012002243U1 (de) 2012-03-02 2012-04-27 Wilhelm Bilstein Gmbh & Co. Kg Messerhalter für Kreismesser

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894083A (en) * 1972-09-21 1975-07-08 Sandoz Ltd Amides
DE3409415A1 (de) * 1984-03-14 1985-09-26 Medice Chem.-Pharm. Fabrik Pütter GmbH & Co KG, 5860 Iserlohn Arzneimittel, insbesondere gegen entzuendungen
HU207104B (en) * 1991-01-25 1993-03-01 Biosignal Kutato Fejlesztoe Kf Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
US5888765A (en) * 1995-06-23 1999-03-30 President And Fellows Of Harvard College Endothelial-cell specific promoter

Also Published As

Publication number Publication date
HUP9800970A3 (en) 2000-04-28
US20010009899A1 (en) 2001-07-26
KR19990083438A (ko) 1999-11-25
DE69927735D1 (de) 2006-03-02
JP2000001439A (ja) 2000-01-07
EP0952159A2 (en) 1999-10-27
US6689813B2 (en) 2004-02-10
EP0952159A3 (en) 2000-08-09
ATE307145T1 (de) 2005-11-15
CA2269995A1 (en) 1999-10-27
HU9800970D0 (en) 1998-06-29
DK0952159T3 (da) 2006-03-06
HU226567B1 (en) 2009-04-28
HUP9800970A2 (hu) 2000-02-28
DE69927735T2 (de) 2006-07-20
EP0952159B1 (en) 2005-10-19

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