ATE307145T1 - Verwendung von phenylhydrazonderivaten als antiinflammatorische und analgetische mittel - Google Patents

Verwendung von phenylhydrazonderivaten als antiinflammatorische und analgetische mittel

Info

Publication number
ATE307145T1
ATE307145T1 AT99107392T AT99107392T ATE307145T1 AT E307145 T1 ATE307145 T1 AT E307145T1 AT 99107392 T AT99107392 T AT 99107392T AT 99107392 T AT99107392 T AT 99107392T AT E307145 T1 ATE307145 T1 AT E307145T1
Authority
AT
Austria
Prior art keywords
inflammatory
analgesic agents
phenylhydrazone derivatives
chem
formula
Prior art date
Application number
AT99107392T
Other languages
English (en)
Inventor
Gyorgy Dr Keri
Janos Dr Szolcsanyi
Erika Dr Pinter
Zsuzsanna Dr Helyes
Judit Dr Erchegyi
Aniko Dr Horvath
Judit Horvath
Istvan Dr Teplan
Laszlo Dr Orfi
Original Assignee
Biostatin Gyogyszerkutato Fejl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biostatin Gyogyszerkutato Fejl filed Critical Biostatin Gyogyszerkutato Fejl
Application granted granted Critical
Publication of ATE307145T1 publication Critical patent/ATE307145T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99107392T 1998-04-27 1999-04-23 Verwendung von phenylhydrazonderivaten als antiinflammatorische und analgetische mittel ATE307145T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9800970A HU226567B1 (en) 1998-04-27 1998-04-27 Use of phenylhydrazon derivates for the preparation of medicaments for the inhibition of neurogenic and non-neurogenic inflammations and for the alleviation of pain

Publications (1)

Publication Number Publication Date
ATE307145T1 true ATE307145T1 (de) 2005-11-15

Family

ID=89996480

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99107392T ATE307145T1 (de) 1998-04-27 1999-04-23 Verwendung von phenylhydrazonderivaten als antiinflammatorische und analgetische mittel

Country Status (10)

Country Link
US (1) US6689813B2 (de)
EP (1) EP0952159B1 (de)
JP (1) JP2000001439A (de)
KR (1) KR19990083438A (de)
AT (1) ATE307145T1 (de)
CA (1) CA2269995A1 (de)
DE (1) DE69927735T2 (de)
DK (1) DK0952159T3 (de)
ES (1) ES2251803T3 (de)
HU (1) HU226567B1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064091A2 (en) * 2001-02-13 2002-08-22 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
AU760257B2 (en) * 1998-12-14 2003-05-08 Palatin Technologies, Inc. Metallopeptide combinatorial libraries and applications
US7049398B1 (en) * 1999-08-12 2006-05-23 Palatin Technologies, Inc. Melanocortin metallopeptide constructs, combinatorial libraries and applications
AU1623801A (en) * 1999-11-19 2001-05-30 Palatin Technologies, Inc. Opioid metallopeptide compositions and methods
US7385025B2 (en) 2000-12-19 2008-06-10 Palatin Technologies, Inc. Metallopeptide compounds
US20040106548A1 (en) * 2001-09-07 2004-06-03 Schmidt Michelle A Conformationally constrained labeled peptides for imaging and therapy
BRPI0509282A (pt) 2004-03-30 2007-09-18 Univ California compostos contendo hidrazida inibidores de cftr e seus usos
CA2671900A1 (en) 2006-12-22 2008-07-03 The Regents Of The University Of California Macromolecular conjugates of cystic fibrosis transmembrane conductance regulator protein inhibitors and uses thereof
US8283351B2 (en) 2007-04-02 2012-10-09 Institute For Oneworld Health Cyclic and acyclic hydrazine derivatives compositions including them and uses thereof
WO2009131951A2 (en) 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
US8207205B2 (en) 2008-04-21 2012-06-26 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
US8343976B2 (en) 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
DE202012002243U1 (de) 2012-03-02 2012-04-27 Wilhelm Bilstein Gmbh & Co. Kg Messerhalter für Kreismesser

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894083A (en) * 1972-09-21 1975-07-08 Sandoz Ltd Amides
DE3409415A1 (de) * 1984-03-14 1985-09-26 Medice Chem.-Pharm. Fabrik Pütter GmbH & Co KG, 5860 Iserlohn Arzneimittel, insbesondere gegen entzuendungen
HU207104B (en) * 1991-01-25 1993-03-01 Biosignal Kutato Fejlesztoe Kf Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
US5888765A (en) * 1995-06-23 1999-03-30 President And Fellows Of Harvard College Endothelial-cell specific promoter

Also Published As

Publication number Publication date
KR19990083438A (ko) 1999-11-25
ES2251803T3 (es) 2006-05-01
DE69927735T2 (de) 2006-07-20
US20010009899A1 (en) 2001-07-26
HUP9800970A3 (en) 2000-04-28
DE69927735D1 (de) 2006-03-02
HU226567B1 (en) 2009-04-28
CA2269995A1 (en) 1999-10-27
HU9800970D0 (en) 1998-06-29
US6689813B2 (en) 2004-02-10
EP0952159B1 (de) 2005-10-19
EP0952159A3 (de) 2000-08-09
JP2000001439A (ja) 2000-01-07
EP0952159A2 (de) 1999-10-27
DK0952159T3 (da) 2006-03-06
HUP9800970A2 (hu) 2000-02-28

Similar Documents

Publication Publication Date Title
DE60036611D1 (de) Indol-derivate als antientzündungs wirkstoffe
EA200200708A1 (ru) Производные бензазола и их применение в качестве модуляторов jnk
EE200100558A (et) Triarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi raviotstarbeline kasutamine
DK1004578T3 (da) 5-oxo-pyrrolidin-2-carboxylsyrehydroxamidderivater
ATE307145T1 (de) Verwendung von phenylhydrazonderivaten als antiinflammatorische und analgetische mittel
HUP0401855A2 (hu) Pirimidin-származékok mint az inzulinszerű növekedési faktor-1 receptor (IGF-1R) modulátorai, eljárás előállításukra, alkalmazásuk és a vegyületeket tartalmazó gyógyszerkészítmények
ATE234299T1 (de) Sulfamoylheteroarylpyrazolverbindungen zur verwendung als analgetisches/entzündungshemmendes mittel
EE200300403A (et) N-asendatud mittearomaatne heterotsükliline ühend, seda sisaldav ravimkompositsioon ning ühendi kasutamine ravimina
DE69811329T2 (de) Imidazolidin-4-on Derivate verwendbar als Antikrebsmittel
RU94038064A (ru) Производные пиперазина и пиперидина, их применение в качестве противопсихотических средств, способ их получения фармацевтическая композиция
ATE252576T1 (de) Heteroarylphenylpyrazolverbindungen zur verwendung als analgetisches/entzündungshemmendes mittel
DE60122555D1 (de) Spiroverbindungen und diese als wirkstoff enthaltende adhäsionsmolekülinhibitoren
ATE440838T1 (de) Pharmazeutisch aktive sulfonylaminosäurederivate
ATE342261T1 (de) Pyranderivate als inhibitoren von ace und nep
IT1256320B (it) Derivati eterociclici
ATE240098T1 (de) Stoffe zur hemmung der bildung des pterygiums und seines postoperative wiederauftretens
DE60007289T2 (de) Verwendung von manzaminen als entzündungshemmende mittel
ATE263769T1 (de) Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen
DE69522118D1 (de) Thiazolidonon- oder oxazolidinonderivate zur behandlung von angina pectoris und zusammensetzungen die diese als wirkstoffe enthält
ATE228134T1 (de) Kondensierte pyrimidinderivate und diese enthaltende pharmazeutische zubereitungen
ATE222583T1 (de) Derivate substituierter amidinonaphthylester
DE60223936D1 (de) Mittel zur anregung des appetits und mittel zur behandlung von anorexie
ATE258934T1 (de) Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe
DE60332851D1 (de) Indolinverbindung und deren medizinische verwendung
DE69916103D1 (de) 3-alkoxylbenzylaminderivate und ihre verwendung als arzneimittel zur behandlung von schizophrenie

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0952159

Country of ref document: EP

REN Ceased due to non-payment of the annual fee