DE60006057D1 - Heteroarylphenylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel - Google Patents
Heteroarylphenylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes MittelInfo
- Publication number
- DE60006057D1 DE60006057D1 DE60006057T DE60006057T DE60006057D1 DE 60006057 D1 DE60006057 D1 DE 60006057D1 DE 60006057 T DE60006057 T DE 60006057T DE 60006057 T DE60006057 T DE 60006057T DE 60006057 D1 DE60006057 D1 DE 60006057D1
- Authority
- DE
- Germany
- Prior art keywords
- halo
- optionally substituted
- compounds
- heteroarylphenylpyrazole
- analgesic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16889099P | 1999-12-03 | 1999-12-03 | |
US168890P | 1999-12-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60006057D1 true DE60006057D1 (de) | 2003-11-27 |
DE60006057T2 DE60006057T2 (de) | 2004-05-27 |
Family
ID=22613380
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60006057T Expired - Fee Related DE60006057T2 (de) | 1999-12-03 | 2000-11-22 | Heteroarylphenylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel |
Country Status (12)
Country | Link |
---|---|
US (1) | US6649636B1 (de) |
EP (1) | EP1104759B1 (de) |
JP (1) | JP3341029B2 (de) |
AT (1) | ATE252576T1 (de) |
BR (1) | BR0006333A (de) |
CA (1) | CA2327256A1 (de) |
DE (1) | DE60006057T2 (de) |
DK (1) | DK1104759T3 (de) |
ES (1) | ES2208227T3 (de) |
MX (1) | MXPA00011845A (de) |
PT (1) | PT1104759E (de) |
TR (1) | TR200302047T4 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
DE60204823T2 (de) | 2001-07-05 | 2005-12-29 | Pfizer Products Inc., Groton | Heterocyclo-alkylsulfonyl Pyrazole als entzündungshemmende/analgetische Mittel |
GT200200183A (es) | 2001-09-28 | 2003-05-23 | Procedimiento para preparar derivados de heterocicloalquilsulfonil pirazol | |
WO2003037335A1 (en) * | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | 5-heteroatom-substituted pyrazoles |
MXPA04003462A (es) | 2001-11-02 | 2005-02-17 | Pfizer Prod Inc | Una sintesis efectiva de pirazoles que contienen un heteroatomo en posicion 5. |
WO2003037351A1 (en) | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | Heterocyclo-alkylsulfonyl pyrazoles and their use as cox-2 inhibitors |
WO2003037330A1 (en) | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | Sulfonyl-and sulfonylheteroaryl-pyrazoles with a hydrazinyl or nitrogen oxide substituent at the 5-position for use as cyclooxygenase inhibitors |
KR100467668B1 (ko) | 2002-08-07 | 2005-01-24 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
US20050043212A1 (en) * | 2002-10-09 | 2005-02-24 | Ford Kirschenbaum | Differential inhibition of p38 map kinase isoforms |
CN1713910A (zh) * | 2002-10-09 | 2005-12-28 | 西奥斯股份有限公司 | 作为p38激酶抑制剂的氮杂吲哚衍生物 |
US20050288299A1 (en) * | 2002-10-09 | 2005-12-29 | Mavunkel Babu J | Azaindole derivatives as inhibitors of p38 kinase |
KR100491317B1 (ko) * | 2002-11-26 | 2005-05-24 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
PL377778A1 (pl) * | 2002-12-02 | 2006-02-20 | Astellas Pharma Inc. | Pochodne pirazolu |
ES2213485B1 (es) * | 2003-02-13 | 2005-12-16 | Almirall Prodesfarma, S.A. | Derivados de la 2-fenilpiran-4-ona. |
ES2214130B1 (es) * | 2003-02-13 | 2005-12-01 | Almirall Prodesfarma, S.A. | 2-3'-bipiridinas. |
ES2214129B1 (es) * | 2003-02-13 | 2005-12-01 | Almirall Prodesfarma, S.A. | 3-fenilfuran-2-onas. |
GB0308318D0 (en) | 2003-04-10 | 2003-05-14 | Merck Sharp & Dohme | Therapeutic agents |
CN1984899B (zh) * | 2004-05-12 | 2011-07-27 | 先灵公司 | Cxcr1和cxcr2趋化因子拮抗剂 |
CA2728095A1 (en) * | 2008-07-17 | 2010-01-21 | Asahi Kasei Pharma Corporation | Pyrazole-containing tricyclic compounds as antagonists of an ep1 receptor |
EP3303332A1 (de) * | 2015-06-01 | 2018-04-11 | Bantam Pharmaceutical, LLC | Substituierte pyrazol- und pyrrolverbindungen sowie verfahren zur verwendung davon zur hemmung der einleitung von translation und behandlung von erkrankungen und leiden im zusammenhang damit |
WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
BR112019011044A2 (pt) | 2016-11-30 | 2019-10-08 | Bantam Pharmaceutical Llc | compostos pirazol substituídos e métodos de uso no tratamento de doenças hiperproliferativas |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH27357A (en) | 1989-09-22 | 1993-06-21 | Fujisawa Pharmaceutical Co | Pyrazole derivatives and pharmaceutical compositions comprising the same |
IL104311A (en) | 1992-02-05 | 1997-07-13 | Fujisawa Pharmaceutical Co | Pyrazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
NZ536355A (en) | 1993-11-30 | 2006-08-31 | Searle & Co | Method of treating inflammation using substituted pyrazolyl benzenesulfonamides |
US5475018A (en) | 1993-11-30 | 1995-12-12 | G. D. Searle & Co. | 1,5-diphenyl pyrazole compounds for treatment of inflammation |
US5401765A (en) | 1993-11-30 | 1995-03-28 | G. D. Searle | 1,4,5-triphenyl pyrazolyl compounds for the treatment of inflammation and inflammation-related disorders |
US5434178A (en) | 1993-11-30 | 1995-07-18 | G.D. Searle & Co. | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
AU3201095A (en) | 1994-07-27 | 1996-02-22 | G.D. Searle & Co. | Substituted thiazoles for the treatment of inflammation |
US5620999A (en) | 1994-07-28 | 1997-04-15 | Weier; Richard M. | Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation |
US5585504A (en) | 1994-09-16 | 1996-12-17 | Merck & Co., Inc. | Process of making cox-2 inhibitors having a lactone bridge |
DE4441758A1 (de) | 1994-11-23 | 1996-05-30 | Siemens Ag | Verfahren und Vorrichtung zur Reduzierung von Oberschwingungs-Netzrückwirkungen eines selbstgeführten Multilevel-Wechselrichters |
US5691374A (en) | 1995-05-18 | 1997-11-25 | Merck Frosst Canada Inc. | Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors |
US5756529A (en) * | 1995-09-29 | 1998-05-26 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies |
GB9520584D0 (en) | 1995-10-09 | 1995-12-13 | Fujisawa Pharmaceutical Co | Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
UA57002C2 (uk) | 1995-10-13 | 2003-06-16 | Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. | Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування |
JP3337477B2 (ja) | 1995-10-30 | 2002-10-21 | メルク フロスト カナダ アンド カンパニー | Cox−2阻害剤のプロドラッグとしての3,4−ジアリール−2−ヒドロキシ−2,5−ジヒドロフラン |
-
2000
- 2000-11-22 EP EP00310356A patent/EP1104759B1/de not_active Expired - Lifetime
- 2000-11-22 ES ES00310356T patent/ES2208227T3/es not_active Expired - Lifetime
- 2000-11-22 PT PT00310356T patent/PT1104759E/pt unknown
- 2000-11-22 TR TR2003/02047T patent/TR200302047T4/xx unknown
- 2000-11-22 DK DK00310356T patent/DK1104759T3/da active
- 2000-11-22 AT AT00310356T patent/ATE252576T1/de not_active IP Right Cessation
- 2000-11-22 DE DE60006057T patent/DE60006057T2/de not_active Expired - Fee Related
- 2000-11-28 US US09/723,608 patent/US6649636B1/en not_active Expired - Fee Related
- 2000-11-30 MX MXPA00011845A patent/MXPA00011845A/es active IP Right Grant
- 2000-12-01 CA CA002327256A patent/CA2327256A1/en not_active Abandoned
- 2000-12-01 JP JP2000366615A patent/JP3341029B2/ja not_active Expired - Fee Related
- 2000-12-04 BR BR0006333-9A patent/BR0006333A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP3341029B2 (ja) | 2002-11-05 |
PT1104759E (pt) | 2004-01-30 |
DE60006057T2 (de) | 2004-05-27 |
CA2327256A1 (en) | 2001-06-03 |
MXPA00011845A (es) | 2002-08-20 |
US6649636B1 (en) | 2003-11-18 |
BR0006333A (pt) | 2001-12-11 |
TR200302047T4 (tr) | 2004-01-21 |
EP1104759A1 (de) | 2001-06-06 |
EP1104759B1 (de) | 2003-10-22 |
JP2001187791A (ja) | 2001-07-10 |
DK1104759T3 (da) | 2004-01-26 |
ES2208227T3 (es) | 2004-06-16 |
ATE252576T1 (de) | 2003-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE234299T1 (de) | Sulfamoylheteroarylpyrazolverbindungen zur verwendung als analgetisches/entzündungshemmendes mittel | |
ATE252576T1 (de) | Heteroarylphenylpyrazolverbindungen zur verwendung als analgetisches/entzündungshemmendes mittel | |
HUP0203971A2 (hu) | Imidazoimidazolok és -triazolok mint gyulladásellenes szerek és ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk | |
FI950309A (fi) | Proliiniamidijohdannaisia | |
ATE180468T1 (de) | Anthranilsäure derivate | |
IE940525L (en) | Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents | |
ATE253545T1 (de) | Biarylessigsäure-derivate und ihre verwendung als cox-2 inhibitoren | |
AR050045A1 (es) | Derivados de pirrolo[3,4-c]pirazol activos como inhibidores de quinasa, procedimiento para su preparacion y composiciones farmaceuticas que los comprenden | |
BR0108816A (pt) | Derivados de quinolina como antagonistas alfa-2 | |
ATE316962T1 (de) | Pyrimidin-derivate als selective inhibitoren von cox-2 | |
DE69428142D1 (de) | Quinolin- oder Quinazolinderivate, deren Herstellung und Verwendung | |
ES2073258T3 (es) | Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica. | |
AU640590B2 (en) | 3-(1h-indazol-3-yl)-4-pyridinamines | |
EA200000532A2 (ru) | НОВЫЕ СОЕДИНЕНИЯ 7-ОКСО-2,3,7,14-ТЕТРАГИДРО-1H-БЕНЗО[b]-ПИРАНО [3,2-h]АКРИДИНКАРБОКСИЛАТА, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ | |
ATE258934T1 (de) | Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe | |
DE69528984D1 (de) | Hemmung der leukotrienbiosynthese mittels harnstoffderivaten |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |