ATE295183T1 - Mittel zur linderung von juckreiz, enthaltend pgd2- antagonisten - Google Patents
Mittel zur linderung von juckreiz, enthaltend pgd2- antagonistenInfo
- Publication number
- ATE295183T1 ATE295183T1 AT99922538T AT99922538T ATE295183T1 AT E295183 T1 ATE295183 T1 AT E295183T1 AT 99922538 T AT99922538 T AT 99922538T AT 99922538 T AT99922538 T AT 99922538T AT E295183 T1 ATE295183 T1 AT E295183T1
- Authority
- AT
- Austria
- Prior art keywords
- agents
- relieving itch
- pgd2 antagonists
- antagonists
- containing pgd2
- Prior art date
Links
- 102100029100 Hematopoietic prostaglandin D synthase Human genes 0.000 title 1
- 101000988802 Homo sapiens Hematopoietic prostaglandin D synthase Proteins 0.000 title 1
- 208000003251 Pruritus Diseases 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- BHMBVRSPMRCCGG-OUTUXVNYSA-N prostaglandin D2 Chemical compound CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O BHMBVRSPMRCCGG-OUTUXVNYSA-N 0.000 title 1
- BHMBVRSPMRCCGG-UHFFFAOYSA-N prostaglandine D2 Natural products CCCCCC(O)C=CC1C(CC=CCCCC(O)=O)C(O)CC1=O BHMBVRSPMRCCGG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15433298 | 1998-06-03 | ||
| PCT/JP1999/002820 WO1999062555A1 (en) | 1998-06-03 | 1999-05-28 | Remedies for itching containing pgd2 antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE295183T1 true ATE295183T1 (de) | 2005-05-15 |
Family
ID=15581844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99922538T ATE295183T1 (de) | 1998-06-03 | 1999-05-28 | Mittel zur linderung von juckreiz, enthaltend pgd2- antagonisten |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1084711B1 (de) |
| JP (1) | JP3857525B2 (de) |
| KR (1) | KR100422920B1 (de) |
| CN (1) | CN1198649C (de) |
| AT (1) | ATE295183T1 (de) |
| AU (1) | AU3955199A (de) |
| CA (1) | CA2333868A1 (de) |
| DE (1) | DE69925270T2 (de) |
| ES (1) | ES2241283T3 (de) |
| TW (1) | TWI239849B (de) |
| WO (1) | WO1999062555A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5430100A (en) | 1999-07-02 | 2001-01-22 | Shionogi & Co., Ltd. | Novel process for producing bicyclic amino alcohol |
| US6410583B1 (en) * | 2000-07-25 | 2002-06-25 | Merck Frosst Canada & Co. | Cyclopentanoindoles, compositions containing such compounds and methods of treatment |
| US7273883B2 (en) | 2000-09-14 | 2007-09-25 | Allergan, Inc. | Prostaglandin EP4 antagonist |
| US7217725B2 (en) | 2000-09-14 | 2007-05-15 | Allergan, Inc. | Prostaglandin D2 antagonist |
| EP1338594A4 (de) * | 2000-11-01 | 2004-06-16 | Shionogi & Co | Pharmazeutische zusammensetzungen mit pgd2-rezeptor-antagonistischer wirkung |
| AU2002229611A1 (en) * | 2000-12-08 | 2002-06-18 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of active compounds capable of modulating the intracellular pathway triggered by the dp receptor in langerhans cells |
| JPWO2003024484A1 (ja) * | 2001-09-14 | 2004-12-24 | 小野薬品工業株式会社 | 掻痒症治療剤 |
| AR038136A1 (es) | 2002-01-24 | 2004-12-29 | Merck Frosst Canada Inc | Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento |
| JPWO2003070252A1 (ja) * | 2002-02-22 | 2005-06-09 | 大正製薬株式会社 | 止痒剤 |
| CA2465103C (en) | 2002-08-09 | 2011-04-26 | Taisho Pharmaceutical Co., Ltd. | Use of a prostaglandin derivative as an anti-pruritic agent |
| US7737182B2 (en) | 2002-08-09 | 2010-06-15 | Taisho Pharmaceutical Co., Ltd. | Pharmaceuticals for xerosis |
| BR0315681A (pt) | 2002-10-30 | 2005-09-06 | Merck Frosst Canada Inc | Composto e seus sais e hidratos farmaceuticamente aceitáveis, composição farmacêutica, métodos para o tratamento de doenças mediadas pela prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, composto ou um seu sal ou solvato farmaceuticamente aceitável, sal ou hidrato do composto, e, uso de um composto ou de um seu sal ou solvato farmaceuticamente aceitável |
| US7714132B2 (en) | 2004-03-11 | 2010-05-11 | Actelion Pharmaceuticals, Ltd. | Tetrahydropyridoindole derivatives |
| WO2006068162A1 (ja) * | 2004-12-24 | 2006-06-29 | Shionogi & Co., Ltd. | 慢性閉塞性肺疾患の治療剤 |
| FR2898893A1 (fr) | 2006-03-27 | 2007-09-28 | Ppg Sipsy Soc Par Actions Simp | Procede d'alkylation diastereoselective d'ether d'oxime du compose nopinone et nouveaux intermediaires pour la synthese de derives 2-amino-nopinone diastereospecifiques substitues sur le carbone 3 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923875A (en) * | 1989-07-10 | 1990-05-08 | Baker Cummins Pharmaceuticals, Inc. | Method for treatment of mast cell-mediated dermatologic disorders |
| ATE337294T1 (de) * | 1995-06-21 | 2006-09-15 | Shionogi & Co | Bizyklische aminoderivate und enthaltende pgd2- antagonisten |
| CA2274591C (en) * | 1996-12-13 | 2005-06-14 | Shionogi & Co., Ltd. | Benzothiophenecarboxamide derivatives and pgd2 antagonists comprising them |
-
1999
- 1999-05-28 KR KR10-2000-7013505A patent/KR100422920B1/ko not_active Expired - Fee Related
- 1999-05-28 DE DE69925270T patent/DE69925270T2/de not_active Expired - Fee Related
- 1999-05-28 AU AU39551/99A patent/AU3955199A/en not_active Abandoned
- 1999-05-28 EP EP99922538A patent/EP1084711B1/de not_active Expired - Lifetime
- 1999-05-28 WO PCT/JP1999/002820 patent/WO1999062555A1/ja not_active Ceased
- 1999-05-28 CN CNB998069248A patent/CN1198649C/zh not_active Expired - Fee Related
- 1999-05-28 AT AT99922538T patent/ATE295183T1/de not_active IP Right Cessation
- 1999-05-28 JP JP2000551809A patent/JP3857525B2/ja not_active Expired - Fee Related
- 1999-05-28 ES ES99922538T patent/ES2241283T3/es not_active Expired - Lifetime
- 1999-05-28 CA CA002333868A patent/CA2333868A1/en not_active Abandoned
- 1999-06-01 TW TW088109046A patent/TWI239849B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010043937A (ko) | 2001-05-25 |
| KR100422920B1 (ko) | 2004-03-12 |
| DE69925270T2 (de) | 2006-02-23 |
| CA2333868A1 (en) | 1999-12-09 |
| WO1999062555A1 (en) | 1999-12-09 |
| AU3955199A (en) | 1999-12-20 |
| JP3857525B2 (ja) | 2006-12-13 |
| EP1084711A1 (de) | 2001-03-21 |
| EP1084711B1 (de) | 2005-05-11 |
| EP1084711A4 (de) | 2003-05-14 |
| CN1304320A (zh) | 2001-07-18 |
| DE69925270D1 (de) | 2005-06-16 |
| ES2241283T3 (es) | 2005-10-16 |
| TWI239849B (en) | 2005-09-21 |
| CN1198649C (zh) | 2005-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |