DE69925270D1 - Mittel zur linderung von juckreiz, enthaltend pgd2- antagonisten - Google Patents

Mittel zur linderung von juckreiz, enthaltend pgd2- antagonisten

Info

Publication number
DE69925270D1
DE69925270D1 DE69925270T DE69925270T DE69925270D1 DE 69925270 D1 DE69925270 D1 DE 69925270D1 DE 69925270 T DE69925270 T DE 69925270T DE 69925270 T DE69925270 T DE 69925270T DE 69925270 D1 DE69925270 D1 DE 69925270D1
Authority
DE
Germany
Prior art keywords
juckreiz
treat
pgd2 antagonists
antagonists
containing pgd2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69925270T
Other languages
English (en)
Other versions
DE69925270T2 (de
Inventor
Akinori Arimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE69925270D1 publication Critical patent/DE69925270D1/de
Application granted granted Critical
Publication of DE69925270T2 publication Critical patent/DE69925270T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69925270T 1998-06-03 1999-05-28 Mittel zur linderung von juckreiz, enthaltend pgd2- antagonisten Expired - Fee Related DE69925270T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15433298 1998-06-03
JP15433298 1998-06-03
PCT/JP1999/002820 WO1999062555A1 (fr) 1998-06-03 1999-05-28 Remedes contre le prurit renfermant des antagonistes vis-a-vis de pgd¿2?

Publications (2)

Publication Number Publication Date
DE69925270D1 true DE69925270D1 (de) 2005-06-16
DE69925270T2 DE69925270T2 (de) 2006-02-23

Family

ID=15581844

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69925270T Expired - Fee Related DE69925270T2 (de) 1998-06-03 1999-05-28 Mittel zur linderung von juckreiz, enthaltend pgd2- antagonisten

Country Status (11)

Country Link
EP (1) EP1084711B1 (de)
JP (1) JP3857525B2 (de)
KR (1) KR100422920B1 (de)
CN (1) CN1198649C (de)
AT (1) ATE295183T1 (de)
AU (1) AU3955199A (de)
CA (1) CA2333868A1 (de)
DE (1) DE69925270T2 (de)
ES (1) ES2241283T3 (de)
TW (1) TWI239849B (de)
WO (1) WO1999062555A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60039876D1 (de) * 1999-07-02 2008-09-25 Shionogi & Co Neuartiges verfahren zur herstellung bicyclischer amino-alkohole
US6410583B1 (en) * 2000-07-25 2002-06-25 Merck Frosst Canada & Co. Cyclopentanoindoles, compositions containing such compounds and methods of treatment
US7217725B2 (en) 2000-09-14 2007-05-15 Allergan, Inc. Prostaglandin D2 antagonist
US7273883B2 (en) 2000-09-14 2007-09-25 Allergan, Inc. Prostaglandin EP4 antagonist
JPWO2002036583A1 (ja) * 2000-11-01 2004-03-11 塩野義製薬株式会社 Ｐｇｄ２受容体拮抗性医薬組成物
WO2002045718A1 (en) * 2000-12-08 2002-06-13 Institut Pasteur De Lille Use of active compounds capable of modulating the intracellular pathway triggered by the dp receptor in langerhans cells
EP1426059A4 (de) * 2001-09-14 2007-01-17 Ono Pharmaceutical Co Mittel zur behandlung von pruritus
AR038136A1 (es) 2002-01-24 2004-12-29 Merck Frosst Canada Inc Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento
CA2463438A1 (en) * 2002-02-22 2003-08-28 Taisho Pharmaceutical Co., Ltd. Antipruritics
US7718701B2 (en) 2002-08-09 2010-05-18 Taisho Pharmaceutical Co., Ltd. Antipruritic agent
US7737182B2 (en) 2002-08-09 2010-06-15 Taisho Pharmaceutical Co., Ltd. Pharmaceuticals for xerosis
JP4332151B2 (ja) 2002-10-30 2009-09-16 メルク フロスト カナダ リミテツド ピリドピロリジンおよびピリドインドリジン誘導体
ATE394399T1 (de) 2004-03-11 2008-05-15 Actelion Pharmaceuticals Ltd Tetrahydropyridoindolderivate
WO2006068162A1 (ja) * 2004-12-24 2006-06-29 Shionogi & Co., Ltd. 慢性閉塞性肺疾患の治療剤
FR2898893A1 (fr) 2006-03-27 2007-09-28 Ppg Sipsy Soc Par Actions Simp Procede d'alkylation diastereoselective d'ether d'oxime du compose nopinone et nouveaux intermediaires pour la synthese de derives 2-amino-nopinone diastereospecifiques substitues sur le carbone 3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923875A (en) * 1989-07-10 1990-05-08 Baker Cummins Pharmaceuticals, Inc. Method for treatment of mast cell-mediated dermatologic disorders
BR9608498B1 (pt) * 1995-06-21 2008-11-18 derivados de amino bicÍclico e antagonista pgd2 contendo os mesmos.
CZ297324B6 (cs) * 1996-12-13 2006-11-15 Shionogi & Co., Ltd. Benzothiofenkarboxamidové deriváty a antagonisty PGD2, které je obsahují

Also Published As

Publication number Publication date
EP1084711A1 (de) 2001-03-21
CA2333868A1 (en) 1999-12-09
WO1999062555A1 (fr) 1999-12-09
CN1304320A (zh) 2001-07-18
ATE295183T1 (de) 2005-05-15
AU3955199A (en) 1999-12-20
EP1084711B1 (de) 2005-05-11
JP3857525B2 (ja) 2006-12-13
KR100422920B1 (ko) 2004-03-12
DE69925270T2 (de) 2006-02-23
ES2241283T3 (es) 2005-10-16
TWI239849B (en) 2005-09-21
KR20010043937A (ko) 2001-05-25
CN1198649C (zh) 2005-04-27
EP1084711A4 (de) 2003-05-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee