DE69927735D1 - Verwendung von Phenylhydrazonderivaten als Antiinflammatorische und Analgetische Mittel - Google Patents

Verwendung von Phenylhydrazonderivaten als Antiinflammatorische und Analgetische Mittel

Info

Publication number
DE69927735D1
DE69927735D1 DE69927735T DE69927735T DE69927735D1 DE 69927735 D1 DE69927735 D1 DE 69927735D1 DE 69927735 T DE69927735 T DE 69927735T DE 69927735 T DE69927735 T DE 69927735T DE 69927735 D1 DE69927735 D1 DE 69927735D1
Authority
DE
Germany
Prior art keywords
inflammatory
analgesic agents
phenylhydrazone derivatives
chem
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69927735T
Other languages
English (en)
Other versions
DE69927735T2 (de
Inventor
Dr Keri
Dr Szolcsanyi
Dr Pinter
Dr Helyes
Dr Erchegyi
Dr Horvath
Judit Horvath
Dr Teplan
Dr Orfi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOSTATIN GYOGYSZERKUTATO FEJL
Original Assignee
BIOSTATIN GYOGYSZERKUTATO FEJL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOSTATIN GYOGYSZERKUTATO FEJL filed Critical BIOSTATIN GYOGYSZERKUTATO FEJL
Publication of DE69927735D1 publication Critical patent/DE69927735D1/de
Application granted granted Critical
Publication of DE69927735T2 publication Critical patent/DE69927735T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69927735T 1998-04-27 1999-04-23 Die Verwendung von Somatostatin-Derivaten und/oder von Phenylhydrazon-Derivaten Expired - Fee Related DE69927735T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9800970 1998-04-27
HU9800970A HU226567B1 (en) 1998-04-27 1998-04-27 Use of phenylhydrazon derivates for the preparation of medicaments for the inhibition of neurogenic and non-neurogenic inflammations and for the alleviation of pain

Publications (2)

Publication Number Publication Date
DE69927735D1 true DE69927735D1 (de) 2006-03-02
DE69927735T2 DE69927735T2 (de) 2006-07-20

Family

ID=89996480

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69927735T Expired - Fee Related DE69927735T2 (de) 1998-04-27 1999-04-23 Die Verwendung von Somatostatin-Derivaten und/oder von Phenylhydrazon-Derivaten

Country Status (10)

Country Link
US (1) US6689813B2 (de)
EP (1) EP0952159B1 (de)
JP (1) JP2000001439A (de)
KR (1) KR19990083438A (de)
AT (1) ATE307145T1 (de)
CA (1) CA2269995A1 (de)
DE (1) DE69927735T2 (de)
DK (1) DK0952159T3 (de)
ES (1) ES2251803T3 (de)
HU (1) HU226567B1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064091A2 (en) * 2001-02-13 2002-08-22 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
JP2002536295A (ja) * 1998-12-14 2002-10-29 パラチン テクノロジーズ， インク． 金属ペプチド組合せライブラリ及びその利用法
US7049398B1 (en) * 1999-08-12 2006-05-23 Palatin Technologies, Inc. Melanocortin metallopeptide constructs, combinatorial libraries and applications
WO2001036006A1 (en) * 1999-11-19 2001-05-25 Palatin Technologies, Inc. Opioid metallopeptide compositions and methods
US7385025B2 (en) * 2000-12-19 2008-06-10 Palatin Technologies, Inc. Metallopeptide compounds
US20040106548A1 (en) * 2001-09-07 2004-06-03 Schmidt Michelle A Conformationally constrained labeled peptides for imaging and therapy
WO2005094374A2 (en) * 2004-03-30 2005-10-13 The Regents Of The University Of California Hydrazide-containing cftr inhibitor compounds and uses thereof
EP2117601A2 (de) 2006-12-22 2009-11-18 The Regents of the University of California Makromolekulare konjugate von zystische-fibrose-transmembran-leitwert-regulatorprotein-inhibitoren und verwendungen davon
US8283351B2 (en) 2007-04-02 2012-10-09 Institute For Oneworld Health Cyclic and acyclic hydrazine derivatives compositions including them and uses thereof
WO2009131951A2 (en) 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
EP2278879B1 (de) 2008-04-21 2016-06-15 PATH Drug Solutions Verbindungen, zusammensetzungen und verfahren umfassend oxadiazolderivate
US8343976B2 (en) 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
DE202012002243U1 (de) 2012-03-02 2012-04-27 Wilhelm Bilstein Gmbh & Co. Kg Messerhalter für Kreismesser

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7312692A (de) * 1972-09-21 1974-03-25
DE3409415A1 (de) * 1984-03-14 1985-09-26 Medice Chem.-Pharm. Fabrik Pütter GmbH & Co KG, 5860 Iserlohn Arzneimittel, insbesondere gegen entzuendungen
HU207104B (en) * 1991-01-25 1993-03-01 Biosignal Kutato Fejlesztoe Kf Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
US5888765A (en) * 1995-06-23 1999-03-30 President And Fellows Of Harvard College Endothelial-cell specific promoter

Also Published As

Publication number Publication date
HU9800970D0 (en) 1998-06-29
US6689813B2 (en) 2004-02-10
DK0952159T3 (da) 2006-03-06
EP0952159A2 (de) 1999-10-27
US20010009899A1 (en) 2001-07-26
HUP9800970A2 (hu) 2000-02-28
HU226567B1 (en) 2009-04-28
EP0952159B1 (de) 2005-10-19
KR19990083438A (ko) 1999-11-25
ES2251803T3 (es) 2006-05-01
JP2000001439A (ja) 2000-01-07
ATE307145T1 (de) 2005-11-15
DE69927735T2 (de) 2006-07-20
CA2269995A1 (en) 1999-10-27
EP0952159A3 (de) 2000-08-09
HUP9800970A3 (en) 2000-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: VOSSIUS & PARTNER, 81675 MUENCHEN

8339 Ceased/non-payment of the annual fee