ES2251767T5 - Receptor que une trail. - Google Patents
Receptor que une trail. Download PDFInfo
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- ES2251767T5 ES2251767T5 ES98908474T ES98908474T ES2251767T5 ES 2251767 T5 ES2251767 T5 ES 2251767T5 ES 98908474 T ES98908474 T ES 98908474T ES 98908474 T ES98908474 T ES 98908474T ES 2251767 T5 ES2251767 T5 ES 2251767T5
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- trail
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US815255 | 1991-12-31 | ||
| US79986197A | 1997-02-13 | 1997-02-13 | |
| US799861 | 1997-02-13 | ||
| US81525597A | 1997-03-12 | 1997-03-12 | |
| US82953697A | 1997-03-28 | 1997-03-28 | |
| US829536 | 1997-03-28 | ||
| US86985297A | 1997-06-04 | 1997-06-04 | |
| US869852 | 1997-06-04 | ||
| US08/883,036 US6072047A (en) | 1997-02-13 | 1997-06-26 | Receptor that binds trail |
| US883036 | 1997-06-26 | ||
| PCT/US1998/002239 WO1998035986A1 (en) | 1997-02-13 | 1998-02-11 | Receptor that binds trail |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ES2251767T3 ES2251767T3 (es) | 2006-05-01 |
| ES2251767T5 true ES2251767T5 (es) | 2012-03-07 |
| ES2251767T9 ES2251767T9 (es) | 2012-10-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98908474T Expired - Lifetime ES2251767T5 (es) | 1997-02-13 | 1998-02-11 | Receptor que une trail. |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6072047A (enExample) |
| EP (2) | EP1005488B9 (enExample) |
| JP (1) | JP5031132B2 (enExample) |
| AT (1) | ATE308561T1 (enExample) |
| AU (1) | AU735686B2 (enExample) |
| CA (1) | CA2279838A1 (enExample) |
| DE (1) | DE69832178T3 (enExample) |
| DK (1) | DK1005488T4 (enExample) |
| ES (1) | ES2251767T5 (enExample) |
| IL (2) | IL131030A0 (enExample) |
| NZ (1) | NZ336929A (enExample) |
| WO (1) | WO1998035986A1 (enExample) |
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| US20080248046A1 (en) * | 1997-03-17 | 2008-10-09 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| US20040136951A1 (en) * | 1997-03-17 | 2004-07-15 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| US20050233958A1 (en) * | 1997-03-17 | 2005-10-20 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| ES2281126T3 (es) * | 1997-03-17 | 2007-09-16 | Human Genome Sciences, Inc. | Receptor 5 que contiene un dominio de muerte. |
| US6342369B1 (en) * | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
| ATE516354T1 (de) * | 1997-05-15 | 2011-07-15 | Genentech Inc | Apo-2-rezeptor |
| US20100152426A1 (en) * | 1997-05-15 | 2010-06-17 | Ashkenazi Avi J | Apo-2 receptor fusion proteins |
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| ES2286856T3 (es) * | 1997-09-12 | 2007-12-01 | Biogen Idec Ma Inc. | Receptores train ricos en cisteina. |
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| IL139419A0 (en) * | 1998-06-12 | 2001-11-25 | Genentech Inc | Monoclonal antibodies, cross-reactive antibodies and method for producing the same |
| US20050281821A1 (en) * | 1999-01-06 | 2005-12-22 | Flavia Pernasetti | Method and composition for angiogenesis inhibition |
| US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
| US6951738B2 (en) | 1999-07-16 | 2005-10-04 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors TR13 and TR14 |
| AU780060B2 (en) * | 1999-07-16 | 2005-02-24 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors TR13 and TR14 |
| CA2381284A1 (en) | 1999-08-04 | 2001-02-15 | Amgen Inc. | Fhm, a novel member of the tnf ligand supergene family |
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| JP2004515203A (ja) * | 1999-08-12 | 2004-05-27 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ヒト腫瘍壊死因子レセプターｔｒ１６ |
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| AU2006201322A1 (en) * | 1999-09-27 | 2006-04-27 | Genentech, Inc. | Methods for making recombinant proteins using apoptosis inhibitors |
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| US7279160B2 (en) * | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
| TWI318983B (en) * | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
| US7476383B2 (en) * | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
| KR100436089B1 (ko) * | 2000-07-06 | 2004-06-14 | 설대우 | 분비성 재조합 트라이머형의 트레일 단백질 생산을 위한 디엔에이 카세트, 테트라사이클린/독시사이클린-유도성아데노-관련 바이러스 벡터, 이 둘의 조합, 및 이들을이용한 유전자 치료 |
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| KR100510234B1 (ko) | 1995-06-29 | 2005-11-25 | 임뮤넥스 코포레이션 | 세포소멸을 유도하는 시토킨 |
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| US20010010924A1 (en) * | 1997-03-14 | 2001-08-02 | Keith Charles Deen | Tumor necrosis factor related receptor, tr6 polynecleotides |
| US6313269B1 (en) * | 1997-03-14 | 2001-11-06 | Smithkline Beecham Corporation | Tumor necrosis factor related receptor, TR6 |
| ES2281126T3 (es) * | 1997-03-17 | 2007-09-16 | Human Genome Sciences, Inc. | Receptor 5 que contiene un dominio de muerte. |
| US6872568B1 (en) * | 1997-03-17 | 2005-03-29 | Human Genome Sciences, Inc. | Death domain containing receptor 5 antibodies |
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| US6342369B1 (en) * | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
| AU8400398A (en) | 1997-07-11 | 1999-02-08 | Trustees Of The University Of Pennsylvania, The | Nucleic acid encoding a novel chemotherapy-induced protein, and methods of use |
| JP2001514888A (ja) | 1997-08-15 | 2001-09-18 | アイドゥン ファーマシューティカルズ， インコーポレイテッド | Ｔｒａｉｌレセプター、これをコードする核酸、およびその使用方法 |
| ES2286856T3 (es) | 1997-09-12 | 2007-12-01 | Biogen Idec Ma Inc. | Receptores train ricos en cisteina. |
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1997
- 1997-06-26 US US08/883,036 patent/US6072047A/en not_active Expired - Lifetime
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1998
- 1998-02-11 WO PCT/US1998/002239 patent/WO1998035986A1/en not_active Ceased
- 1998-02-11 CA CA002279838A patent/CA2279838A1/en not_active Abandoned
- 1998-02-11 NZ NZ336929A patent/NZ336929A/xx not_active IP Right Cessation
- 1998-02-11 ES ES98908474T patent/ES2251767T5/es not_active Expired - Lifetime
- 1998-02-11 EP EP98908474A patent/EP1005488B9/en not_active Expired - Lifetime
- 1998-02-11 EP EP05023483A patent/EP1676857A3/en not_active Withdrawn
- 1998-02-11 IL IL13103098A patent/IL131030A0/xx active IP Right Grant
- 1998-02-11 DE DE69832178T patent/DE69832178T3/de not_active Expired - Lifetime
- 1998-02-11 DK DK98908474.4T patent/DK1005488T4/da active
- 1998-02-11 JP JP53582098A patent/JP5031132B2/ja not_active Expired - Lifetime
- 1998-02-11 AT AT98908474T patent/ATE308561T1/de active
- 1998-02-11 AU AU66505/98A patent/AU735686B2/en not_active Ceased
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1999
- 1999-07-21 IL IL131030A patent/IL131030A/en not_active IP Right Cessation
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2000
- 2000-03-27 US US09/536,201 patent/US6569642B1/en not_active Expired - Fee Related
- 2000-05-25 US US09/578,392 patent/US6642358B1/en not_active Expired - Fee Related
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| IL131030A0 (en) | 2001-01-28 |
| EP1005488A4 (en) | 2003-03-05 |
| US6072047A (en) | 2000-06-06 |
| WO1998035986A1 (en) | 1998-08-20 |
| ATE308561T1 (de) | 2005-11-15 |
| EP1005488B2 (en) | 2011-12-14 |
| ES2251767T3 (es) | 2006-05-01 |
| US6569642B1 (en) | 2003-05-27 |
| EP1005488B1 (en) | 2005-11-02 |
| IL131030A (en) | 2011-02-28 |
| DE69832178T2 (de) | 2006-07-20 |
| EP1676857A2 (en) | 2006-07-05 |
| NZ336929A (en) | 2000-11-24 |
| ES2251767T9 (es) | 2012-10-17 |
| DE69832178D1 (de) | 2005-12-08 |
| DE69832178T3 (de) | 2012-03-29 |
| EP1005488A1 (en) | 2000-06-07 |
| HK1029796A1 (en) | 2001-04-12 |
| EP1676857A3 (en) | 2007-04-04 |
| EP1005488B9 (en) | 2012-04-18 |
| JP5031132B2 (ja) | 2012-09-19 |
| DK1005488T3 (da) | 2006-03-06 |
| JP2002514069A (ja) | 2002-05-14 |
| AU735686B2 (en) | 2001-07-12 |
| CA2279838A1 (en) | 1998-08-20 |
| US6642358B1 (en) | 2003-11-04 |
| DK1005488T4 (da) | 2012-01-16 |
| AU6650598A (en) | 1998-09-08 |
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