CA2279838A1 - Receptor that binds trail - Google Patents
Receptor that binds trail Download PDFInfo
- Publication number
- CA2279838A1 CA2279838A1 CA002279838A CA2279838A CA2279838A1 CA 2279838 A1 CA2279838 A1 CA 2279838A1 CA 002279838 A CA002279838 A CA 002279838A CA 2279838 A CA2279838 A CA 2279838A CA 2279838 A1 CA2279838 A1 CA 2279838A1
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- Prior art keywords
- trail
- polypeptide
- dna
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79986197A | 1997-02-13 | 1997-02-13 | |
| US08/799,861 | 1997-02-13 | ||
| US81525597A | 1997-03-12 | 1997-03-12 | |
| US08/815,255 | 1997-03-12 | ||
| US82953697A | 1997-03-28 | 1997-03-28 | |
| US08/829,536 | 1997-03-28 | ||
| US86985297A | 1997-06-04 | 1997-06-04 | |
| US08/869,852 | 1997-06-04 | ||
| US08/883,036 | 1997-06-25 | ||
| US08/883,036 US6072047A (en) | 1997-02-13 | 1997-06-26 | Receptor that binds trail |
| PCT/US1998/002239 WO1998035986A1 (en) | 1997-02-13 | 1998-02-11 | Receptor that binds trail |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2279838A1 true CA2279838A1 (en) | 1998-08-20 |
Family
ID=27542220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002279838A Abandoned CA2279838A1 (en) | 1997-02-13 | 1998-02-11 | Receptor that binds trail |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6072047A (enExample) |
| EP (2) | EP1005488B9 (enExample) |
| JP (1) | JP5031132B2 (enExample) |
| AT (1) | ATE308561T1 (enExample) |
| AU (1) | AU735686B2 (enExample) |
| CA (1) | CA2279838A1 (enExample) |
| DE (1) | DE69832178T3 (enExample) |
| DK (1) | DK1005488T4 (enExample) |
| ES (1) | ES2251767T5 (enExample) |
| IL (2) | IL131030A0 (enExample) |
| NZ (1) | NZ336929A (enExample) |
| WO (1) | WO1998035986A1 (enExample) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20020160446A1 (en) * | 2000-11-14 | 2002-10-31 | Holtzman Douglas A. | Novel genes encoding proteins having prognostic diagnostic preventive therapeutic and other uses |
| US6313269B1 (en) * | 1997-03-14 | 2001-11-06 | Smithkline Beecham Corporation | Tumor necrosis factor related receptor, TR6 |
| US6872568B1 (en) | 1997-03-17 | 2005-03-29 | Human Genome Sciences, Inc. | Death domain containing receptor 5 antibodies |
| US20080248046A1 (en) * | 1997-03-17 | 2008-10-09 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| US20040136951A1 (en) * | 1997-03-17 | 2004-07-15 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| US20050233958A1 (en) * | 1997-03-17 | 2005-10-20 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| ES2281126T3 (es) * | 1997-03-17 | 2007-09-16 | Human Genome Sciences, Inc. | Receptor 5 que contiene un dominio de muerte. |
| US6342369B1 (en) * | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
| ATE516354T1 (de) * | 1997-05-15 | 2011-07-15 | Genentech Inc | Apo-2-rezeptor |
| US20100152426A1 (en) * | 1997-05-15 | 2010-06-17 | Ashkenazi Avi J | Apo-2 receptor fusion proteins |
| JP2001514888A (ja) * | 1997-08-15 | 2001-09-18 | アイドゥン ファーマシューティカルズ， インコーポレイテッド | Ｔｒａｉｌレセプター、これをコードする核酸、およびその使用方法 |
| ES2286856T3 (es) * | 1997-09-12 | 2007-12-01 | Biogen Idec Ma Inc. | Receptores train ricos en cisteina. |
| US6252050B1 (en) * | 1998-06-12 | 2001-06-26 | Genentech, Inc. | Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method |
| IL139419A0 (en) * | 1998-06-12 | 2001-11-25 | Genentech Inc | Monoclonal antibodies, cross-reactive antibodies and method for producing the same |
| US20050281821A1 (en) * | 1999-01-06 | 2005-12-22 | Flavia Pernasetti | Method and composition for angiogenesis inhibition |
| US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
| US6951738B2 (en) | 1999-07-16 | 2005-10-04 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors TR13 and TR14 |
| AU780060B2 (en) * | 1999-07-16 | 2005-02-24 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors TR13 and TR14 |
| CA2381284A1 (en) | 1999-08-04 | 2001-02-15 | Amgen Inc. | Fhm, a novel member of the tnf ligand supergene family |
| WO2001010908A1 (en) | 1999-08-04 | 2001-02-15 | Amgen Inc. | Ntr3, a member of the tnf-receptor supergene family |
| JP2004515203A (ja) * | 1999-08-12 | 2004-05-27 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ヒト腫瘍壊死因子レセプターｔｒ１６ |
| US20030134788A1 (en) * | 1999-08-12 | 2003-07-17 | Baker Kevin P. | Human tumor necrosis factor receptor TR16 |
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| KR100510234B1 (ko) | 1995-06-29 | 2005-11-25 | 임뮤넥스 코포레이션 | 세포소멸을 유도하는 시토킨 |
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1997
- 1997-06-26 US US08/883,036 patent/US6072047A/en not_active Expired - Lifetime
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1998
- 1998-02-11 WO PCT/US1998/002239 patent/WO1998035986A1/en not_active Ceased
- 1998-02-11 CA CA002279838A patent/CA2279838A1/en not_active Abandoned
- 1998-02-11 NZ NZ336929A patent/NZ336929A/xx not_active IP Right Cessation
- 1998-02-11 ES ES98908474T patent/ES2251767T5/es not_active Expired - Lifetime
- 1998-02-11 EP EP98908474A patent/EP1005488B9/en not_active Expired - Lifetime
- 1998-02-11 EP EP05023483A patent/EP1676857A3/en not_active Withdrawn
- 1998-02-11 IL IL13103098A patent/IL131030A0/xx active IP Right Grant
- 1998-02-11 DE DE69832178T patent/DE69832178T3/de not_active Expired - Lifetime
- 1998-02-11 DK DK98908474.4T patent/DK1005488T4/da active
- 1998-02-11 JP JP53582098A patent/JP5031132B2/ja not_active Expired - Lifetime
- 1998-02-11 AT AT98908474T patent/ATE308561T1/de active
- 1998-02-11 AU AU66505/98A patent/AU735686B2/en not_active Ceased
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1999
- 1999-07-21 IL IL131030A patent/IL131030A/en not_active IP Right Cessation
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2000
- 2000-03-27 US US09/536,201 patent/US6569642B1/en not_active Expired - Fee Related
- 2000-05-25 US US09/578,392 patent/US6642358B1/en not_active Expired - Fee Related
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| IL131030A0 (en) | 2001-01-28 |
| EP1005488A4 (en) | 2003-03-05 |
| US6072047A (en) | 2000-06-06 |
| WO1998035986A1 (en) | 1998-08-20 |
| ATE308561T1 (de) | 2005-11-15 |
| EP1005488B2 (en) | 2011-12-14 |
| ES2251767T3 (es) | 2006-05-01 |
| US6569642B1 (en) | 2003-05-27 |
| EP1005488B1 (en) | 2005-11-02 |
| IL131030A (en) | 2011-02-28 |
| DE69832178T2 (de) | 2006-07-20 |
| EP1676857A2 (en) | 2006-07-05 |
| NZ336929A (en) | 2000-11-24 |
| ES2251767T9 (es) | 2012-10-17 |
| DE69832178D1 (de) | 2005-12-08 |
| DE69832178T3 (de) | 2012-03-29 |
| ES2251767T5 (es) | 2012-03-07 |
| EP1005488A1 (en) | 2000-06-07 |
| HK1029796A1 (en) | 2001-04-12 |
| EP1676857A3 (en) | 2007-04-04 |
| EP1005488B9 (en) | 2012-04-18 |
| JP5031132B2 (ja) | 2012-09-19 |
| DK1005488T3 (da) | 2006-03-06 |
| JP2002514069A (ja) | 2002-05-14 |
| AU735686B2 (en) | 2001-07-12 |
| US6642358B1 (en) | 2003-11-04 |
| DK1005488T4 (da) | 2012-01-16 |
| AU6650598A (en) | 1998-09-08 |
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