ES2228357T3 - Composiciones que contienen substancias solubles en grasas en una matriz de hidrato de carbono. - Google Patents
Composiciones que contienen substancias solubles en grasas en una matriz de hidrato de carbono.Info
- Publication number
- ES2228357T3 ES2228357T3 ES00113875T ES00113875T ES2228357T3 ES 2228357 T3 ES2228357 T3 ES 2228357T3 ES 00113875 T ES00113875 T ES 00113875T ES 00113875 T ES00113875 T ES 00113875T ES 2228357 T3 ES2228357 T3 ES 2228357T3
- Authority
- ES
- Spain
- Prior art keywords
- weight
- composition according
- maltose
- molecular weight
- carbohydrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 79
- 239000000126 substance Substances 0.000 title claims abstract description 21
- 239000011159 matrix material Substances 0.000 title claims abstract description 19
- 229910052799 carbon Inorganic materials 0.000 title claims description 9
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 title claims description 4
- 239000003925 fat Substances 0.000 title description 16
- 230000036571 hydration Effects 0.000 title 1
- 238000006703 hydration reaction Methods 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 34
- 235000014633 carbohydrates Nutrition 0.000 claims abstract description 34
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims abstract description 26
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims abstract description 26
- 235000000346 sugar Nutrition 0.000 claims abstract description 13
- 235000013305 food Nutrition 0.000 claims abstract description 5
- 239000007903 gelatin capsule Substances 0.000 claims abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 28
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims description 26
- 229930006000 Sucrose Natural products 0.000 claims description 26
- 239000005720 sucrose Substances 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- 239000000839 emulsion Substances 0.000 claims description 21
- 239000000843 powder Substances 0.000 claims description 15
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 14
- VYGQUTWHTHXGQB-UHFFFAOYSA-N Retinol hexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-UHFFFAOYSA-N 0.000 claims description 13
- 239000011769 retinyl palmitate Substances 0.000 claims description 13
- 229940108325 retinyl palmitate Drugs 0.000 claims description 13
- 235000019172 retinyl palmitate Nutrition 0.000 claims description 13
- 239000008103 glucose Substances 0.000 claims description 12
- 239000006188 syrup Substances 0.000 claims description 12
- 235000020357 syrup Nutrition 0.000 claims description 12
- 239000003963 antioxidant agent Substances 0.000 claims description 11
- 235000006708 antioxidants Nutrition 0.000 claims description 11
- 239000011732 tocopherol Substances 0.000 claims description 11
- 229940088594 vitamin Drugs 0.000 claims description 11
- 229930003231 vitamin Natural products 0.000 claims description 11
- 235000013343 vitamin Nutrition 0.000 claims description 11
- 239000011782 vitamin Substances 0.000 claims description 11
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims description 10
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims description 10
- 235000010385 ascorbyl palmitate Nutrition 0.000 claims description 10
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 10
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims description 10
- 230000003078 antioxidant effect Effects 0.000 claims description 9
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims description 9
- 235000010378 sodium ascorbate Nutrition 0.000 claims description 9
- 229960005055 sodium ascorbate Drugs 0.000 claims description 9
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims description 9
- 229920002774 Maltodextrin Polymers 0.000 claims description 8
- 239000005913 Maltodextrin Substances 0.000 claims description 8
- 239000003995 emulsifying agent Substances 0.000 claims description 8
- 229940035034 maltodextrin Drugs 0.000 claims description 8
- 229960001295 tocopherol Drugs 0.000 claims description 8
- 229930091371 Fructose Natural products 0.000 claims description 6
- 239000005715 Fructose Substances 0.000 claims description 6
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 6
- 235000019155 vitamin A Nutrition 0.000 claims description 6
- 239000011719 vitamin A Substances 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 5
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 4
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims description 4
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims description 4
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 4
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 4
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 3
- 229920001214 Polysorbate 60 Polymers 0.000 claims description 3
- -1 apoester Chemical compound 0.000 claims description 3
- 235000021466 carotenoid Nutrition 0.000 claims description 3
- 150000001747 carotenoids Chemical class 0.000 claims description 3
- 239000000787 lecithin Substances 0.000 claims description 3
- 235000010445 lecithin Nutrition 0.000 claims description 3
- 229940067606 lecithin Drugs 0.000 claims description 3
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims description 3
- 229930003799 tocopherol Natural products 0.000 claims description 3
- 235000019149 tocopherols Nutrition 0.000 claims description 3
- JKQXZKUSFCKOGQ-JLGXGRJMSA-N (3R,3'R)-beta,beta-carotene-3,3'-diol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-JLGXGRJMSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 2
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims description 2
- 239000004217 Citranaxanthin Substances 0.000 claims description 2
- SLQHGWZKKZPZEK-JKEZLOPUSA-N Citranaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C(=O)C)C=CC=C(/C)C=CC1=C(C)CCCC1(C)C SLQHGWZKKZPZEK-JKEZLOPUSA-N 0.000 claims description 2
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 2
- 229920000881 Modified starch Polymers 0.000 claims description 2
- 239000004368 Modified starch Substances 0.000 claims description 2
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 2
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 claims description 2
- JKQXZKUSFCKOGQ-LQFQNGICSA-N Z-zeaxanthin Natural products C([C@H](O)CC=1C)C(C)(C)C=1C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-LQFQNGICSA-N 0.000 claims description 2
- QOPRSMDTRDMBNK-RNUUUQFGSA-N Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCC(O)C1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C QOPRSMDTRDMBNK-RNUUUQFGSA-N 0.000 claims description 2
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims description 2
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 claims description 2
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 claims description 2
- DFMMVLFMMAQXHZ-CMGSAFQJSA-N apocarotenal Chemical compound O=CC(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)C=CC1=C(C)CCCC1(C)C DFMMVLFMMAQXHZ-CMGSAFQJSA-N 0.000 claims description 2
- 229940019834 apocarotenal Drugs 0.000 claims description 2
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims description 2
- 235000013793 astaxanthin Nutrition 0.000 claims description 2
- 239000001168 astaxanthin Substances 0.000 claims description 2
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims description 2
- 229940022405 astaxanthin Drugs 0.000 claims description 2
- 235000013734 beta-carotene Nutrition 0.000 claims description 2
- 239000011648 beta-carotene Substances 0.000 claims description 2
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims description 2
- 229960002747 betacarotene Drugs 0.000 claims description 2
- 235000012682 canthaxanthin Nutrition 0.000 claims description 2
- FDSDTBUPSURDBL-DKLMTRRASA-N canthaxanthin Chemical compound CC=1C(=O)CCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)CCC1(C)C FDSDTBUPSURDBL-DKLMTRRASA-N 0.000 claims description 2
- 235000019247 citranaxanthin Nutrition 0.000 claims description 2
- PRDJTOVRIHGKNU-ZWERVMMHSA-N citranaxanthin Chemical compound CC(=O)\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C PRDJTOVRIHGKNU-ZWERVMMHSA-N 0.000 claims description 2
- PRDJTOVRIHGKNU-UHFFFAOYSA-N citranaxanthine Natural products CC(=O)C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C PRDJTOVRIHGKNU-UHFFFAOYSA-N 0.000 claims description 2
- 239000008121 dextrose Substances 0.000 claims description 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 2
- 150000002148 esters Chemical group 0.000 claims description 2
- 229930195729 fatty acid Natural products 0.000 claims description 2
- 239000000194 fatty acid Substances 0.000 claims description 2
- 150000004665 fatty acids Chemical class 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- 235000019426 modified starch Nutrition 0.000 claims description 2
- 229960000342 retinol acetate Drugs 0.000 claims description 2
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 claims description 2
- 235000019173 retinyl acetate Nutrition 0.000 claims description 2
- 239000011770 retinyl acetate Substances 0.000 claims description 2
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 claims description 2
- 235000019166 vitamin D Nutrition 0.000 claims description 2
- 239000011710 vitamin D Substances 0.000 claims description 2
- 235000019165 vitamin E Nutrition 0.000 claims description 2
- 239000011709 vitamin E Substances 0.000 claims description 2
- 235000019168 vitamin K Nutrition 0.000 claims description 2
- 239000011712 vitamin K Substances 0.000 claims description 2
- 235000010930 zeaxanthin Nutrition 0.000 claims description 2
- 239000001775 zeaxanthin Substances 0.000 claims description 2
- 229940043269 zeaxanthin Drugs 0.000 claims description 2
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims description 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 4
- 235000019197 fats Nutrition 0.000 claims 4
- 229940114079 arachidonic acid Drugs 0.000 claims 2
- 235000021342 arachidonic acid Nutrition 0.000 claims 2
- UHZZMRAGKVHANO-UHFFFAOYSA-M chlormequat chloride Chemical compound [Cl-].C[N+](C)(C)CCCl UHZZMRAGKVHANO-UHFFFAOYSA-M 0.000 claims 2
- 230000002378 acidificating effect Effects 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 150000004347 all-trans-retinol derivatives Chemical class 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 125000002640 tocopherol group Chemical class 0.000 claims 1
- 239000000243 solution Substances 0.000 description 21
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- 150000002632 lipids Chemical class 0.000 description 8
- 238000001704 evaporation Methods 0.000 description 5
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- 239000013078 crystal Substances 0.000 description 4
- GZQKNULLWNGMCW-PWQABINMSA-N lipid A (E. coli) Chemical compound O1[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H]1OC[C@@H]1[C@@H](O)[C@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OP(O)(O)=O)O1 GZQKNULLWNGMCW-PWQABINMSA-N 0.000 description 4
- 125000004365 octenyl group Chemical group C(=CCCCCCC)* 0.000 description 4
- 229940074404 sodium succinate Drugs 0.000 description 4
- ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 description 4
- 229940045997 vitamin a Drugs 0.000 description 4
- 239000003921 oil Substances 0.000 description 3
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
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- 239000008273 gelatin Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 239000012047 saturated solution Substances 0.000 description 2
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- 239000011627 DL-alpha-tocopherol Substances 0.000 description 1
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- MKYBYDHXWVHEJW-UHFFFAOYSA-N N-[1-oxo-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propan-2-yl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(C(C)NC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 MKYBYDHXWVHEJW-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920001213 Polysorbate 20 Polymers 0.000 description 1
- 235000007201 Saccharum officinarum Nutrition 0.000 description 1
- 240000000111 Saccharum officinarum Species 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- 235000019728 animal nutrition Nutrition 0.000 description 1
- 235000019282 butylated hydroxyanisole Nutrition 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 125000003071 maltose group Chemical group 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- 125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 238000005204 segregation Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000013097 stability assessment Methods 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 150000003445 sucroses Chemical class 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Edible Oils And Fats (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Lubricants (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99113039 | 1999-07-06 | ||
| EP99113039 | 1999-07-06 | ||
| EP99118177 | 1999-09-13 | ||
| EP99118177 | 1999-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2228357T3 true ES2228357T3 (es) | 2005-04-16 |
Family
ID=26153042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00113875T Expired - Lifetime ES2228357T3 (es) | 1999-07-06 | 2000-06-30 | Composiciones que contienen substancias solubles en grasas en una matriz de hidrato de carbono. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6887502B2 (enExample) |
| EP (1) | EP1066761B1 (enExample) |
| JP (1) | JP2001058945A (enExample) |
| KR (1) | KR100714527B1 (enExample) |
| CN (1) | CN1199695C (enExample) |
| AT (1) | ATE277527T1 (enExample) |
| AU (2) | AU773754B2 (enExample) |
| CA (1) | CA2313339A1 (enExample) |
| DE (1) | DE60014255T2 (enExample) |
| DK (1) | DK1066761T3 (enExample) |
| ES (1) | ES2228357T3 (enExample) |
| MX (1) | MX230345B (enExample) |
| NO (1) | NO317782B1 (enExample) |
| TW (1) | TWI244897B (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8828432B2 (en) | 1996-10-28 | 2014-09-09 | General Mills, Inc. | Embedding and encapsulation of sensitive components into a matrix to obtain discrete controlled release particles |
| AU747549B2 (en) | 1998-03-23 | 2002-05-16 | General Mills Inc. | Encapsulation of components into edible products |
| US7201923B1 (en) | 1998-03-23 | 2007-04-10 | General Mills, Inc. | Encapsulation of sensitive liquid components into a matrix to obtain discrete shelf-stable particles |
| US6500463B1 (en) | 1999-10-01 | 2002-12-31 | General Mills, Inc. | Encapsulation of sensitive components into a matrix to obtain discrete shelf-stable particles |
| US6756405B2 (en) * | 2000-04-18 | 2004-06-29 | Natural Asa | Conjugated linoleic acid powder |
| US6468568B1 (en) * | 2000-06-16 | 2002-10-22 | General Mills, Inc. | Oligosaccharide encapsulated mineral and vitamin ingredients |
| US6436453B1 (en) * | 2000-06-16 | 2002-08-20 | General Mills, Inc. | Production of oil encapsulated minerals and vitamins in a glassy matrix |
| US6558718B1 (en) | 2000-06-19 | 2003-05-06 | General Mills, Inc. | Nutrient clusters for food products and methods of preparation |
| CA2357265C (en) * | 2001-04-24 | 2004-04-13 | University Of British Columbia | Improved additive for livestock feeds |
| JP3583380B2 (ja) * | 2001-04-26 | 2004-11-04 | 高砂香料工業株式会社 | コーティング剤およびコーティング粉末 |
| US6936279B2 (en) | 2002-06-18 | 2005-08-30 | Zeavision Llc | Microcrystalline zeaxanthin with high bioavailability in oily carrier formulations |
| US7431986B2 (en) | 2002-07-24 | 2008-10-07 | General Mills, Inc. | Encapsulation of sensitive components using pre-emulsification |
| EP1428526A1 (en) * | 2002-12-13 | 2004-06-16 | Rijksuniversiteit Groningen | Formulation for fast dissolution of lipophilic compounds |
| JP4153330B2 (ja) * | 2003-02-28 | 2008-09-24 | サントリー株式会社 | 高度不飽和脂肪酸のアスコルビン酸エステル化合物の粉末組成物の製造法およびそれらの組成物 |
| WO2005110123A1 (en) * | 2003-04-25 | 2005-11-24 | Abbott Laboratories | Stable nutritional powder containing ascorbyl palmitate |
| US7332178B2 (en) * | 2003-04-25 | 2008-02-19 | Abbott Laboratories | Stable nutritional powder containing ascorbyl palmitate |
| US20040231684A1 (en) * | 2003-05-20 | 2004-11-25 | Zawadzki Michael A. | Smoking article and smoking article filter |
| JP4666932B2 (ja) * | 2004-02-27 | 2011-04-06 | 株式会社スギヨ | 糖質−カロテノイド系色素脂溶体および／または固溶体の製造法 |
| EP1616486A1 (en) * | 2004-07-13 | 2006-01-18 | Friesland Brands B.V. | Powdered compositions containing an edible oil and their use in food products |
| DE102004051245A1 (de) * | 2004-10-20 | 2006-04-27 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Vitamin C-Solubilisat |
| US20080311255A1 (en) * | 2005-02-02 | 2008-12-18 | Dsm Ip Assets B.V. | Powder Compositions |
| DE102005030952A1 (de) | 2005-06-30 | 2007-01-18 | Basf Ag | Verfahren zur Herstellung einer wässrigen Suspension und einer pulverförmigen Zubereitung eines oder mehrerer Carotinoide |
| WO2007009601A1 (en) | 2005-07-20 | 2007-01-25 | Dsm Ip Assets B.V. | Novel stabilized carotenoid compositions |
| US7803413B2 (en) | 2005-10-31 | 2010-09-28 | General Mills Ip Holdings Ii, Llc. | Encapsulation of readily oxidizable components |
| JP5459939B2 (ja) * | 2006-06-09 | 2014-04-02 | 富士フイルム株式会社 | カロチノイド含有エマルジョン組成物、その製造方法、それを含む食品及び化粧品 |
| DE202006010606U1 (de) * | 2006-07-07 | 2007-11-22 | Sensient Food Colors Germany Gmbh & Co. Kg | Zubereitung für Lebensmittel |
| CN1927188B (zh) * | 2006-08-25 | 2010-10-06 | 西南合成制药股份有限公司 | 一种耐压型维生素e微囊及其制备方法 |
| AU2007295178B2 (en) * | 2006-09-15 | 2013-04-18 | Echo Pharmaceuticals B.V. | Granulate containing a pharmaceutically active substance and anemulsifier and method for its manufacture |
| EP2063861B1 (en) | 2006-09-15 | 2015-02-25 | Echo Pharmaceuticals B.V. | Dosage unit for sublingual, buccal or oral administration of water-insoluble pharmaceutically active substances |
| WO2008088037A1 (ja) * | 2007-01-18 | 2008-07-24 | National University Corporation Chiba University | 微粒子製剤 |
| EP1969952A1 (en) * | 2007-03-07 | 2008-09-17 | Friesland Brands B.V. | Allergen-free or dairy free LCPUFA powdered compositions and the use thereof in food products and especially infant formulas |
| US20080254119A1 (en) * | 2007-04-16 | 2008-10-16 | Wyeth | Imbedded liquid lubricants for tableting |
| WO2009000404A2 (en) * | 2007-06-22 | 2008-12-31 | Dsm Ip Assets B.V.. | Fortification of sugar |
| EP2011835A1 (en) | 2007-07-06 | 2009-01-07 | Chr. Hansen A/S | A colouring composition comprising starch derivatives as a hydrocolloid |
| KR20100047869A (ko) * | 2007-07-19 | 2010-05-10 | 디에스엠 아이피 어셋츠 비.브이. | 친유성 헬스 성분의 정제화가능한 배합물 |
| WO2010070005A1 (en) | 2008-12-19 | 2010-06-24 | Chr. Hansen A/S | A bile resistant bacillus composition |
| EP2385766B2 (en) | 2009-01-07 | 2022-03-23 | Chr. Hansen Natural Colors A/S | A composition comprising calcium carbonate as a white pigment |
| EP2210593A3 (en) | 2009-01-21 | 2011-05-18 | DSM IP Assets B.V. | Tablettable formulations of vitamin A and derivatives thereof |
| US20100215758A1 (en) * | 2009-02-25 | 2010-08-26 | Joar Opheim | Effervescent nutritional and/or dietary supplement composition |
| WO2011129284A1 (ja) * | 2010-04-16 | 2011-10-20 | 三栄源エフ・エフ・アイ株式会社 | クルクミンの風味のマスキング方法 |
| WO2012106777A1 (en) | 2011-02-11 | 2012-08-16 | Clover Corporation Limited | Nutritional compositions and uses thereof |
| JP6095998B2 (ja) * | 2013-02-15 | 2017-03-15 | 理研ビタミン株式会社 | 粉末状ｌ−アスコルビン酸脂肪酸エステル製剤の製造方法 |
| US20140272011A1 (en) * | 2013-03-15 | 2014-09-18 | Mccormick & Company, Incorporated | Encapsulation compositions comprising of spices, herbs, fruit, and vegetable powders |
| PL2993995T3 (pl) * | 2013-05-06 | 2018-08-31 | Dsm Ip Assets B.V. | Proszkowy preparat z witaminą E |
| US20150305386A1 (en) * | 2014-04-28 | 2015-10-29 | Eduardo Fernandez | Compositions for nutritional supplementation |
| CA3176674A1 (en) | 2015-05-18 | 2016-11-24 | 5071, Inc. | Homogenous cannabis compositions and methods of making the same |
| CN108366605A (zh) * | 2015-12-10 | 2018-08-03 | 帝斯曼知识产权资产管理有限公司 | 维生素制剂 |
| KR102416361B1 (ko) * | 2016-04-01 | 2022-07-04 | 디에스엠 아이피 어셋츠 비.브이. | 루테인 및/또는 제아잔틴의 신규 타정가능 제형 |
| CN108324699A (zh) * | 2017-01-20 | 2018-07-27 | 浙江医药股份有限公司新昌制药厂 | 稳定的脂溶性活性成分组合物、微囊及其制备方法和应用 |
| EP3351118A1 (en) * | 2017-01-20 | 2018-07-25 | Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory | Fat-soluble active ingredient composition, microcapsule and uses thereof and process of preparation |
| MX2019014734A (es) * | 2017-06-08 | 2020-02-07 | Int Flavors & Fragrances Inc | Granulos que contienen sabor a base de carbohidratos y metodos para producirlos. |
| CN107307390A (zh) * | 2017-07-10 | 2017-11-03 | 北京素维生物科技有限公司 | 功能营养强化剂组合物及制备方法 |
| CN107296278A (zh) * | 2017-07-10 | 2017-10-27 | 北京素维生物科技有限公司 | 一种功能营养强化剂组合物及其制备方法 |
| CN107252109A (zh) * | 2017-07-10 | 2017-10-17 | 北京素维生物科技有限公司 | 功能营养强化剂组合物及其制备方法 |
| US20190015383A1 (en) * | 2017-07-14 | 2019-01-17 | 5071, Inc. | Cannabinoid compositions and methods of preparation thereof |
| SG11202003789PA (en) * | 2017-10-31 | 2020-05-28 | Roquette America Inc | Method for the formulation of oil-soluble substances, and powders obtainable thereof |
| US20210000157A1 (en) * | 2018-03-15 | 2021-01-07 | Dsm Ip Assets B.V. | Extrudate comprising vitamin a |
| CN115137018B (zh) * | 2021-03-30 | 2024-03-15 | 新发药业有限公司 | 一种维生素a及其衍生物组合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2809895A (en) * | 1955-07-05 | 1957-10-15 | Sunkist Growers Inc | Solid flavoring composition and method of preparing the same |
| US3704137A (en) * | 1970-06-11 | 1972-11-28 | Eugene E Beck | Essential oil composition and method of preparing the same |
| US3971852A (en) * | 1973-06-12 | 1976-07-27 | Polak's Frutal Works, Inc. | Process of encapsulating an oil and product produced thereby |
| GB1490814A (en) | 1975-07-22 | 1977-11-02 | Cadbury Ltd | Heat-resistant chocolate product and method of manufacturing same |
| JPS5498317A (en) | 1978-01-17 | 1979-08-03 | Fuji Seitou Kk | Production of water soluble vitamin a containing powder |
| US4820534A (en) * | 1984-03-19 | 1989-04-11 | General Foods Corporation | Fixation of volatiles in extruded glass substrates |
| JPH0826345B2 (ja) | 1986-07-10 | 1996-03-13 | 株式会社林原生物化学研究所 | 固状油溶性物質の製造方法 |
| WO1989008988A1 (en) * | 1988-03-30 | 1989-10-05 | Melkridge Pty Ltd | Dairy food substitute |
| US5087461A (en) * | 1989-10-02 | 1992-02-11 | Nabisco Brands, Inc. | Double-encapsulated compositions containing volatile and/or labile components, and processes for preparation and use thereof |
| US5124162A (en) | 1991-11-26 | 1992-06-23 | Kraft General Foods, Inc. | Spray-dried fixed flavorants in a carbohydrate substrate and process |
| DE4141351A1 (de) * | 1991-12-14 | 1993-06-17 | Basf Ag | Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung |
| ATE218065T1 (de) * | 1996-08-09 | 2002-06-15 | Mannatech Inc | Zusammensetzungen auf pflanzliicher kohlenhydratbasis als nahrungsergänzungsstoffe |
| US5972395A (en) * | 1997-04-25 | 1999-10-26 | Kraft Foods, Inc. | Method of preparing glass stabilized material |
| US6475539B1 (en) * | 1998-05-07 | 2002-11-05 | Abbott Laboratories | Nutritionally complete low pH enteral formula |
| EP1064856B1 (en) * | 1999-06-30 | 2005-04-06 | Givaudan SA | Encapsulation of active ingredients |
-
2000
- 2000-06-30 ES ES00113875T patent/ES2228357T3/es not_active Expired - Lifetime
- 2000-06-30 DK DK00113875T patent/DK1066761T3/da active
- 2000-06-30 EP EP00113875A patent/EP1066761B1/en not_active Revoked
- 2000-06-30 DE DE60014255T patent/DE60014255T2/de not_active Revoked
- 2000-06-30 AT AT00113875T patent/ATE277527T1/de not_active IP Right Cessation
- 2000-07-03 TW TW089113128A patent/TWI244897B/zh not_active IP Right Cessation
- 2000-07-03 AU AU43807/00A patent/AU773754B2/en not_active Ceased
- 2000-07-03 KR KR1020000037632A patent/KR100714527B1/ko not_active Expired - Fee Related
- 2000-07-04 CA CA002313339A patent/CA2313339A1/en not_active Abandoned
- 2000-07-04 MX MXPA00006617 patent/MX230345B/es active IP Right Grant
- 2000-07-05 CN CNB001200674A patent/CN1199695C/zh not_active Expired - Fee Related
- 2000-07-05 NO NO20003474A patent/NO317782B1/no unknown
- 2000-07-06 JP JP2000204686A patent/JP2001058945A/ja active Pending
-
2002
- 2002-03-08 US US10/093,724 patent/US6887502B2/en not_active Expired - Fee Related
-
2004
- 2004-09-03 AU AU2004208690A patent/AU2004208690A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1066761B1 (en) | 2004-09-29 |
| DE60014255D1 (de) | 2004-11-04 |
| DE60014255T2 (de) | 2005-11-03 |
| CA2313339A1 (en) | 2001-01-06 |
| NO20003474L (no) | 2001-01-08 |
| TWI244897B (en) | 2005-12-11 |
| MX230345B (es) | 2005-09-05 |
| US6887502B2 (en) | 2005-05-03 |
| AU2004208690A1 (en) | 2004-09-30 |
| EP1066761A3 (en) | 2001-07-18 |
| KR100714527B1 (ko) | 2007-05-07 |
| EP1066761A2 (en) | 2001-01-10 |
| MXPA00006617A (es) | 2002-02-01 |
| AU4380700A (en) | 2001-01-11 |
| DK1066761T3 (da) | 2005-01-03 |
| NO317782B1 (no) | 2004-12-13 |
| CN1199695C (zh) | 2005-05-04 |
| AU773754B2 (en) | 2004-06-03 |
| KR20010049696A (ko) | 2001-06-15 |
| US20020127303A1 (en) | 2002-09-12 |
| CN1279112A (zh) | 2001-01-10 |
| JP2001058945A (ja) | 2001-03-06 |
| NO20003474D0 (no) | 2000-07-05 |
| ATE277527T1 (de) | 2004-10-15 |
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