ES2192608T3 - Uso de derivados de alilamina tales como terbinafina, en la fabricacion de un medicamento para el tratamiento de la infeccion por helicobacter pylori de enfermedades asociadas. - Google Patents

Uso de derivados de alilamina tales como terbinafina, en la fabricacion de un medicamento para el tratamiento de la infeccion por helicobacter pylori de enfermedades asociadas.

Info

Publication number
ES2192608T3
ES2192608T3 ES96924889T ES96924889T ES2192608T3 ES 2192608 T3 ES2192608 T3 ES 2192608T3 ES 96924889 T ES96924889 T ES 96924889T ES 96924889 T ES96924889 T ES 96924889T ES 2192608 T3 ES2192608 T3 ES 2192608T3
Authority
ES
Spain
Prior art keywords
infection
alilamine
terbinafine
derivatives
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96924889T
Other languages
English (en)
Inventor
Ivan James Dalton Lindley
Neil Stewart Ryder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2192608T3 publication Critical patent/ES2192608T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)

Abstract

USO DE COMPUESTOS DE FORMULA (I), EN QUE R TIENE VARIOS SIGNIFICADOS, EN FORMA DE BASE LIBRE O EN FORMA DE SAL FARMACEUTICAMENTE ACEPTABLE, COMO AGENTES CONTRA LA INFECCION POR H. PYLORI Y ENFERMEDADES ASOCIADAS.
ES96924889T 1995-07-06 1996-07-05 Uso de derivados de alilamina tales como terbinafina, en la fabricacion de un medicamento para el tratamiento de la infeccion por helicobacter pylori de enfermedades asociadas. Expired - Lifetime ES2192608T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9513750.1A GB9513750D0 (en) 1995-07-06 1995-07-06 Use of allylamines

Publications (1)

Publication Number Publication Date
ES2192608T3 true ES2192608T3 (es) 2003-10-16

Family

ID=10777201

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96924889T Expired - Lifetime ES2192608T3 (es) 1995-07-06 1996-07-05 Uso de derivados de alilamina tales como terbinafina, en la fabricacion de un medicamento para el tratamiento de la infeccion por helicobacter pylori de enfermedades asociadas.

Country Status (27)

Country Link
US (1) US5935998A (es)
EP (1) EP0863752B1 (es)
JP (1) JP3680950B2 (es)
KR (1) KR100425401B1 (es)
CN (1) CN1204881C (es)
AT (1) ATE232723T1 (es)
AU (1) AU715270B2 (es)
CA (1) CA2219678C (es)
CY (1) CY2465B1 (es)
CZ (1) CZ289440B6 (es)
DE (1) DE69626301T2 (es)
DK (1) DK0863752T3 (es)
ES (1) ES2192608T3 (es)
GB (1) GB9513750D0 (es)
HK (1) HK1011527A1 (es)
HU (1) HU224311B1 (es)
IL (1) IL122853A (es)
MX (1) MX9710093A (es)
MY (1) MY132436A (es)
NO (1) NO317496B1 (es)
PL (1) PL187704B1 (es)
RU (1) RU2193402C2 (es)
SI (1) SI0863752T1 (es)
SK (1) SK282874B6 (es)
TW (1) TW522011B (es)
WO (1) WO1997002026A1 (es)
ZA (1) ZA965749B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0001315D0 (en) * 2000-01-20 2000-03-08 Novartis Ag Organic compounds
US7244703B2 (en) * 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
KR20030066186A (ko) * 2002-02-05 2003-08-09 한솔케미언스 주식회사 (e)-터비나핀 또는 이의 염산염의 제조방법
EP1706128B1 (en) * 2003-12-08 2010-07-21 CPEX Pharmaceuticals, Inc. Pharmaceutical compositions and methods for insulin treatment
RU2449805C1 (ru) 2011-01-27 2012-05-10 Общество С Ограниченной Ответственностью "Гармония" Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716943C2 (de) * 1976-04-28 1986-08-14 Sandoz-Patent-GmbH, 7850 Lörrach N-(3-Phenyl-2-propenyl)-N-(1-naphthylmethyl)-amine, ihre Verwendung und Herstellung
DE2862103D1 (en) * 1977-08-19 1982-11-18 Sandoz Ag Propenyl amines, processes for their production and pharmaceutical compositions containing them
DE3020113A1 (de) * 1979-06-08 1980-12-18 Sandoz Ag 2-(1-naphthyl)piperidin-derivat, dessen herstellung sowie die verwendung als antimykotika
ATE10272T1 (de) * 1979-08-22 1984-11-15 Sandoz Ag Propenylamine, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zusammensetzungen und ihre verwendung als arzneimittel.
US5132459A (en) * 1979-08-22 1992-07-21 Sandoz Ltd. Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
US4894375A (en) * 1986-09-29 1990-01-16 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
CA2020888A1 (en) * 1989-07-27 1991-01-28 Philippe Guerry Substituted aminoalkoxybenzene derivatives
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
DE4317449A1 (de) * 1993-05-19 1994-11-24 Asche Ag Arzneimittel zur Behandlung von Erkrankungen des Magen-Darm-Traktes

Also Published As

Publication number Publication date
IL122853A (en) 2001-04-30
KR19990028725A (ko) 1999-04-15
CY2465B1 (en) 2005-06-03
GB9513750D0 (en) 1995-09-06
CZ289440B6 (cs) 2002-01-16
PL323305A1 (en) 1998-03-16
CN1189775A (zh) 1998-08-05
NO975790L (no) 1997-12-09
CZ1798A3 (cs) 1998-03-18
WO1997002026A1 (en) 1997-01-23
TW522011B (en) 2003-03-01
AU6519596A (en) 1997-02-05
CA2219678C (en) 2006-10-10
SK698A3 (en) 1998-05-06
EP0863752B1 (en) 2003-02-19
AU715270B2 (en) 2000-01-20
JPH11508580A (ja) 1999-07-27
ATE232723T1 (de) 2003-03-15
DE69626301T2 (de) 2003-10-16
HK1011527A1 (en) 1999-07-16
EP0863752A1 (en) 1998-09-16
DK0863752T3 (da) 2003-04-22
MX9710093A (es) 1998-03-31
SI0863752T1 (en) 2003-06-30
NO975790D0 (no) 1997-12-09
ZA965749B (en) 1998-01-05
DE69626301D1 (de) 2003-03-27
HU224311B1 (hu) 2005-07-28
CN1204881C (zh) 2005-06-08
SK282874B6 (sk) 2003-01-09
JP3680950B2 (ja) 2005-08-10
IL122853A0 (en) 1998-08-16
KR100425401B1 (ko) 2004-07-16
CA2219678A1 (en) 1997-01-23
HUP9802929A2 (hu) 1999-09-28
PL187704B1 (pl) 2004-09-30
HUP9802929A3 (en) 1999-10-28
NO317496B1 (no) 2004-11-08
US5935998A (en) 1999-08-10
MY132436A (en) 2007-10-31
RU2193402C2 (ru) 2002-11-27

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