ES2191297T3 - Procedimiento para la desbencilacion de dibencilbiotina. - Google Patents
Procedimiento para la desbencilacion de dibencilbiotina.Info
- Publication number
- ES2191297T3 ES2191297T3 ES98916981T ES98916981T ES2191297T3 ES 2191297 T3 ES2191297 T3 ES 2191297T3 ES 98916981 T ES98916981 T ES 98916981T ES 98916981 T ES98916981 T ES 98916981T ES 2191297 T3 ES2191297 T3 ES 2191297T3
- Authority
- ES
- Spain
- Prior art keywords
- dibencilbiotine
- debencilation
- procedure
- biotin
- debylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
La invención se refiere a un nuevo procedimiento para la debencilación selectiva de biotina de dibencilo que se produce como producto intermedio en la síntesis de biotina pero habitualmente no se aísla.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19712952A DE19712952A1 (de) | 1997-03-27 | 1997-03-27 | Verfahren zur Entbenzylierung von Dibenzylbiotin |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2191297T3 true ES2191297T3 (es) | 2003-09-01 |
Family
ID=7824831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98916981T Expired - Lifetime ES2191297T3 (es) | 1997-03-27 | 1998-03-17 | Procedimiento para la desbencilacion de dibencilbiotina. |
Country Status (10)
Country | Link |
---|---|
US (1) | US6140507A (es) |
EP (1) | EP0971931B1 (es) |
JP (1) | JP2001516363A (es) |
KR (1) | KR20010005573A (es) |
CN (1) | CN1101820C (es) |
DE (2) | DE19712952A1 (es) |
DK (1) | DK0971931T3 (es) |
ES (1) | ES2191297T3 (es) |
HK (1) | HK1022695A1 (es) |
WO (1) | WO1998043979A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100657186B1 (ko) * | 1998-12-24 | 2006-12-14 | 스미또모 가가꾸 가부시키가이샤 | 헥사하이드로-2-옥소-1H-티에노[3,4-d]이미다졸-4-펜탄산의 제조 방법 |
WO2004041830A2 (en) * | 2002-11-07 | 2004-05-21 | Orchid Chemicals & Pharmaceuticals Ltd | An improved process for the preparation of biotin |
CN100488967C (zh) * | 2003-11-10 | 2009-05-20 | 浙江医药股份有限公司新昌制药厂 | 双苄生物素的制备方法 |
CN101215291B (zh) * | 2008-01-10 | 2010-12-29 | 复旦大学 | (+)-生物素及其衍生物的合成方法 |
CN103788112B (zh) * | 2012-11-02 | 2016-03-09 | 菏泽市方明制药有限公司 | 一种苄基生物素脱苄制备生物素的方法 |
CN103772409B (zh) * | 2013-12-31 | 2016-06-08 | 浙江新和成股份有限公司 | 一种脱苄基合成d-生物素的方法 |
CN104926828B (zh) * | 2014-03-22 | 2019-02-19 | 上海创诺制药有限公司 | 一种由双苄生物素制备d-生物素的方法 |
JPWO2020050342A1 (ja) * | 2018-09-07 | 2021-08-30 | 株式会社トクヤマ | N,n’−ジベンジルビオチンのジシクロへキシルアミン塩及びその製造方法 |
CN109627254B (zh) * | 2018-12-13 | 2020-04-28 | 浙江圣达生物药业股份有限公司 | 一种d-生物素的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4537973A (en) * | 1980-03-12 | 1985-08-27 | Sumitomo Chemical Company, Limited | Process for preparing biotin |
JPS58124791A (ja) * | 1982-01-19 | 1983-07-25 | Sumitomo Chem Co Ltd | ビオチンの製造法 |
DE69232830T2 (de) * | 1992-04-06 | 2003-07-03 | Council Scient Ind Res | Verfahren zur Synthese von D(+)-Biotin |
-
1997
- 1997-03-27 DE DE19712952A patent/DE19712952A1/de not_active Withdrawn
-
1998
- 1998-03-17 KR KR1019997008636A patent/KR20010005573A/ko active IP Right Grant
- 1998-03-17 WO PCT/EP1998/001545 patent/WO1998043979A1/de active IP Right Grant
- 1998-03-17 US US09/381,907 patent/US6140507A/en not_active Expired - Fee Related
- 1998-03-17 JP JP54110398A patent/JP2001516363A/ja not_active Withdrawn
- 1998-03-17 DK DK98916981T patent/DK0971931T3/da active
- 1998-03-17 DE DE59807249T patent/DE59807249D1/de not_active Expired - Fee Related
- 1998-03-17 ES ES98916981T patent/ES2191297T3/es not_active Expired - Lifetime
- 1998-03-17 CN CN98803623A patent/CN1101820C/zh not_active Expired - Fee Related
- 1998-03-17 EP EP98916981A patent/EP0971931B1/de not_active Expired - Lifetime
-
2000
- 2000-03-21 HK HK00101715A patent/HK1022695A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0971931B1 (de) | 2003-02-19 |
US6140507A (en) | 2000-10-31 |
HK1022695A1 (en) | 2000-08-18 |
WO1998043979A1 (de) | 1998-10-08 |
CN1101820C (zh) | 2003-02-19 |
KR20010005573A (ko) | 2001-01-15 |
DE19712952A1 (de) | 1998-10-01 |
EP0971931A1 (de) | 2000-01-19 |
CN1251106A (zh) | 2000-04-19 |
JP2001516363A (ja) | 2001-09-25 |
DE59807249D1 (de) | 2003-03-27 |
DK0971931T3 (da) | 2003-06-10 |
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