ES2190222T3 - Derivados de 3-(2-oxo-(1,3')bipirrolindinil-3-iliden-metil)-cefem. - Google Patents
Derivados de 3-(2-oxo-(1,3')bipirrolindinil-3-iliden-metil)-cefem.Info
- Publication number
- ES2190222T3 ES2190222T3 ES99927894T ES99927894T ES2190222T3 ES 2190222 T3 ES2190222 T3 ES 2190222T3 ES 99927894 T ES99927894 T ES 99927894T ES 99927894 T ES99927894 T ES 99927894T ES 2190222 T3 ES2190222 T3 ES 2190222T3
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- ocor
- formula
- cooch
- coor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 8
- 239000001257 hydrogen Substances 0.000 abstract 8
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/48—Methylene radicals, substituted by hetero rings
- C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98110888 | 1998-06-15 | ||
| EP98117099 | 1998-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2190222T3 true ES2190222T3 (es) | 2003-07-16 |
Family
ID=26149347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99927894T Expired - Lifetime ES2190222T3 (es) | 1998-06-15 | 1999-06-07 | Derivados de 3-(2-oxo-(1,3')bipirrolindinil-3-iliden-metil)-cefem. |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP1087980B1 (https=) |
| JP (1) | JP3872955B2 (https=) |
| KR (1) | KR100411915B1 (https=) |
| CN (1) | CN1136222C (https=) |
| AR (1) | AR018675A1 (https=) |
| AT (1) | ATE231871T1 (https=) |
| AU (1) | AU754732B2 (https=) |
| BE (1) | BE2014C034I2 (https=) |
| BR (2) | BRPI9911178C1 (https=) |
| CA (1) | CA2334568C (https=) |
| CO (1) | CO5080758A1 (https=) |
| DE (1) | DE69905162T2 (https=) |
| DK (1) | DK1087980T3 (https=) |
| ES (1) | ES2190222T3 (https=) |
| FR (1) | FR14C0044I2 (https=) |
| GT (1) | GT199900084A (https=) |
| HU (1) | HUP0105426A3 (https=) |
| ID (1) | ID27686A (https=) |
| IL (1) | IL139872A0 (https=) |
| LU (1) | LU92564I2 (https=) |
| MA (1) | MA26650A1 (https=) |
| NO (1) | NO20006350D0 (https=) |
| PA (1) | PA8475701A1 (https=) |
| PE (1) | PE20000645A1 (https=) |
| PL (1) | PL344994A1 (https=) |
| SV (1) | SV1999000075A (https=) |
| TN (1) | TNSN99114A1 (https=) |
| WO (1) | WO1999065920A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6267100A (en) * | 1999-07-07 | 2001-01-30 | F. Hoffmann-La Roche Ag | Vinylpyrrolidinone derivatives with substituted thiazole ring |
| DK1148140T3 (da) | 2000-04-19 | 2007-01-08 | Basilea Pharmaceutica Ag | Fremgangsmåde til fremstilling af D-asparaginderivater |
| US6504025B2 (en) * | 2000-05-24 | 2003-01-07 | Basilea Pharmaceutica Ag | Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives |
| ES2329244T3 (es) * | 2003-03-27 | 2009-11-24 | Basilea Pharmaceutica Ag | Cefalosporina en forma cristalina. |
| EP1656930A1 (en) | 2004-11-10 | 2006-05-17 | Basilea Pharmaceutica AG | Stabilized freeze-dried formulation for cephalosporin derivatives |
| AR071318A1 (es) | 2008-04-15 | 2010-06-09 | Basilea Pharmaceutica Ag | Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso |
| WO2010072672A1 (en) | 2008-12-24 | 2010-07-01 | Basilea Pharmaceutica Ag | New crystal polymorphs of ceftobiprole |
| KR20120016662A (ko) * | 2009-05-25 | 2012-02-24 | 산도즈 아게 | 세프토비프롤 메도카릴의 제조 방법 |
| MX2012012798A (es) | 2010-05-10 | 2013-02-27 | Basilea Pharmaceutica Internat Ltd | Proceso de oxidacion para preparar derivados de 3-formil-cefem. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2281090T3 (es) * | 1996-11-06 | 2007-09-16 | Basilea Pharmaceutica Ag | Derivados de vinilpirrolidona-cefalosporina. |
| TW415949B (en) * | 1996-12-19 | 2000-12-21 | Hoffmann La Roche | Vinyl pyrrolidine cephalosporin derivatives with basic substituents |
-
1999
- 1999-06-07 BR BRPI9911178A patent/BRPI9911178C1/pt unknown
- 1999-06-07 KR KR10-2000-7014203A patent/KR100411915B1/ko not_active Expired - Lifetime
- 1999-06-07 IL IL13987299A patent/IL139872A0/xx unknown
- 1999-06-07 JP JP2000554745A patent/JP3872955B2/ja not_active Expired - Lifetime
- 1999-06-07 DK DK99927894T patent/DK1087980T3/da active
- 1999-06-07 DE DE69905162T patent/DE69905162T2/de not_active Expired - Lifetime
- 1999-06-07 WO PCT/EP1999/003907 patent/WO1999065920A1/en not_active Ceased
- 1999-06-07 ID IDW20002565A patent/ID27686A/id unknown
- 1999-06-07 BR BRPI9911178A patent/BRPI9911178B8/pt not_active IP Right Cessation
- 1999-06-07 CA CA002334568A patent/CA2334568C/en not_active Expired - Lifetime
- 1999-06-07 ES ES99927894T patent/ES2190222T3/es not_active Expired - Lifetime
- 1999-06-07 CN CNB998073474A patent/CN1136222C/zh not_active Expired - Lifetime
- 1999-06-07 HU HU0105426A patent/HUP0105426A3/hu unknown
- 1999-06-07 PL PL99344994A patent/PL344994A1/xx unknown
- 1999-06-07 AT AT99927894T patent/ATE231871T1/de active
- 1999-06-07 EP EP99927894A patent/EP1087980B1/en not_active Expired - Lifetime
- 1999-06-07 AU AU45081/99A patent/AU754732B2/en not_active Expired
- 1999-06-11 CO CO99036886A patent/CO5080758A1/es unknown
- 1999-06-11 PE PE1999000521A patent/PE20000645A1/es not_active Application Discontinuation
- 1999-06-11 AR ARP990102825A patent/AR018675A1/es active IP Right Grant
- 1999-06-14 PA PA19998475701A patent/PA8475701A1/es unknown
- 1999-06-14 GT GT199900084A patent/GT199900084A/es unknown
- 1999-06-15 MA MA25625A patent/MA26650A1/fr unknown
- 1999-06-15 TN TNTNSN99114A patent/TNSN99114A1/fr unknown
- 1999-06-15 SV SV1999000075A patent/SV1999000075A/es not_active Application Discontinuation
-
2000
- 2000-12-13 NO NO20006350A patent/NO20006350D0/no not_active Application Discontinuation
-
2014
- 2014-05-15 BE BE2014C034C patent/BE2014C034I2/fr unknown
- 2014-06-11 FR FR14C0044C patent/FR14C0044I2/fr active Active
- 2014-10-01 LU LU92564C patent/LU92564I2/xx unknown
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