ES2179910T3 - Modificacion cristalina del cdch, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen. - Google Patents
Modificacion cristalina del cdch, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen.Info
- Publication number
- ES2179910T3 ES2179910T3 ES96119134T ES96119134T ES2179910T3 ES 2179910 T3 ES2179910 T3 ES 2179910T3 ES 96119134 T ES96119134 T ES 96119134T ES 96119134 T ES96119134 T ES 96119134T ES 2179910 T3 ES2179910 T3 ES 2179910T3
- Authority
- ES
- Spain
- Prior art keywords
- cdch
- procedure
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102100034741 Cyclin-dependent kinase 20 Human genes 0.000 title abstract 2
- 101500014379 Lymnaea stagnalis Ovulation hormone Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000013078 crystal Substances 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19546249A DE19546249A1 (de) | 1995-12-12 | 1995-12-12 | Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2179910T3 true ES2179910T3 (es) | 2003-02-01 |
Family
ID=7779831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96119134T Expired - Lifetime ES2179910T3 (es) | 1995-12-12 | 1996-11-29 | Modificacion cristalina del cdch, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen. |
Country Status (42)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2303768A1 (es) * | 2006-09-08 | 2008-08-16 | Quimica Sintentica, S.A. | Nueva forma cristalina de moxifloxacino clorhidrato. |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895233A (zh) * | 1997-09-25 | 2007-01-17 | 拜尔公司 | 控释活性化合物的药物制剂 |
| DE19751948A1 (de) | 1997-11-24 | 1999-05-27 | Bayer Ag | Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren |
| US6509327B1 (en) | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
| US6716830B2 (en) | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
| US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
| DK1128831T3 (da) | 1998-11-10 | 2005-01-17 | Bayer Healthcare Ag | Farmaceutisk moxifloxacinpræparat |
| DE19854357A1 (de) * | 1998-11-25 | 2000-05-31 | Bayer Ag | Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| DE19854356A1 (de) * | 1998-11-25 | 2000-05-31 | Bayer Ag | Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| DE19854355A1 (de) * | 1998-11-25 | 2000-05-31 | Bayer Ag | Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| DE19908449A1 (de) * | 1999-02-26 | 2000-08-31 | Bayer Ag | Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure |
| EP1562942A1 (en) * | 2002-10-31 | 2005-08-17 | Ranbaxy Laboratories, Ltd. | Amorphous moxifloxacin hydrochloride |
| EP2113505A1 (en) | 2003-04-09 | 2009-11-04 | Dr. Reddy's Laboratories, Ltd. | A crystalline form III of anhydrous moxifloxacin hydrochloride and processes for the preparation thereof |
| EP1651630A1 (en) * | 2003-08-05 | 2006-05-03 | Matrix Laboratories Ltd | An improved process for the preparation of moxifloxacin hydrochloride |
| WO2005054240A1 (en) * | 2003-11-20 | 2005-06-16 | Chemi Spa | Polymorphs of 1-cyclopropyl-7-([s,s]-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof |
| ITMI20032259A1 (it) | 2003-11-20 | 2005-05-21 | Chemi Spa | Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione |
| US7491725B2 (en) | 2004-02-06 | 2009-02-17 | Bristol-Myers Squibb Company | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| DE102004015981A1 (de) * | 2004-04-01 | 2005-10-20 | Bayer Healthcare Ag | Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| DE102004063347A1 (de) * | 2004-12-23 | 2006-07-13 | Stada Arzneimittel Ag | Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate |
| WO2007033515A1 (fr) * | 2005-09-21 | 2007-03-29 | Shenzhen Tys R & D Co., Ltd. | Formulation orale contenant de la moxifloxacine et son procédé de préparation |
| GB0612422D0 (en) * | 2006-06-23 | 2006-08-02 | Generics Uk Ltd | Novel hydrate form |
| CN101484411A (zh) | 2006-06-27 | 2009-07-15 | 桑多斯股份公司 | 盐的新制备方法 |
| JP2010509305A (ja) * | 2006-11-13 | 2010-03-25 | シプラ・リミテッド | モキシフロキサシン塩酸塩の合成方法 |
| EP1992626A1 (en) * | 2007-05-10 | 2008-11-19 | Sandoz AG | Process for the preparation of moxifloxacin hydrochloride |
| EP2083010A1 (en) * | 2008-01-08 | 2009-07-29 | Chemo Ibérica, S.A. | Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof |
| EP2154137A1 (en) | 2008-08-04 | 2010-02-17 | Chemo Ibérica, S.A. | Crystalline form of moxifloxacin base |
| EP2349220B1 (en) | 2008-10-09 | 2012-07-25 | Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi | Using of organic solvents in wet granulation of moxifloxacin |
| WO2010052726A1 (en) * | 2008-11-06 | 2010-05-14 | Hetero Research Foundation | Novel polymorph of moxifloxacin hydrochloride |
| ES2467105T5 (es) | 2008-12-08 | 2017-12-05 | Ratiopharm Gmbh | Moxifloxacino compactado |
| WO2010131054A1 (en) | 2009-05-15 | 2010-11-18 | Bradford Pharma Limited | Redox drug derivatives |
| WO2011121596A2 (en) * | 2010-04-01 | 2011-10-06 | Neuland Laboratories Ltd. | Crystal modification of moxifloxacin hydrochloride |
| BRPI1106900A2 (pt) | 2011-12-26 | 2013-11-05 | Ems Sa | Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção |
| FR2992218B1 (fr) | 2012-06-22 | 2015-01-23 | Rivopharm Sa | Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation |
| CN102924449B (zh) * | 2012-10-30 | 2015-08-12 | 重庆福安药业集团庆余堂制药有限公司 | 盐酸莫西沙星h晶型及其制备方法和药物组合物 |
| EP2928892B1 (en) | 2012-12-04 | 2018-03-21 | Mankind Pharma Ltd. | An improved process for the preparation of moxifloxacin hydrochloride |
| RU2561037C2 (ru) * | 2013-02-07 | 2015-08-20 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Антибактериальная фармацевтическая композиция и способ ее получения |
| AU2014239965A1 (en) | 2013-03-15 | 2015-09-24 | Melinta Subsidiary Corp. | Methods of treating infections in overweight and obese patients using antibiotics |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3601567A1 (de) * | 1986-01-21 | 1987-07-23 | Bayer Ag | 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate |
| DK164287A (da) * | 1986-03-31 | 1987-10-01 | Sankyo Co | Quinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf og deres anvendelse |
| AU609974B2 (en) * | 1988-05-18 | 1991-05-09 | Warner-Lambert Company | Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids |
| DE3910663A1 (de) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-alkylchinoloncarbonsaeuren |
| RO108347B1 (ro) * | 1989-10-30 | 1994-04-28 | Bellon Labor Sa Roger | DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA |
| TW209865B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-01-10 | 1993-07-21 | Bayer Ag | |
| CA2128601C (en) * | 1992-01-31 | 2003-07-15 | Hiroyuki Nagano | Quinolone carboxylic acid derivatives in crystalline hydrate form |
| DE4234078A1 (de) * | 1992-10-09 | 1994-04-14 | Bayer Ag | Chinoloncarbonsäuren |
| JP3268098B2 (ja) * | 1992-12-25 | 2002-03-25 | 第一製薬株式会社 | 二環性環状アミン誘導体 |
| ZA946853B (en) * | 1993-09-10 | 1995-04-24 | Daiichi Seiyaku Co | Crystals of antimicrobial compound. |
| EP0676199B1 (en) * | 1994-04-07 | 1998-09-02 | Pfizer Inc. | Use of trovafloxacin or derivatives thereof for the manufacture of a medicament for the treatment of H. pylori infections |
-
1995
- 1995-12-12 DE DE19546249A patent/DE19546249A1/de not_active Withdrawn
-
1996
- 1996-11-22 MA MA24398A patent/MA24342A1/fr unknown
- 1996-11-25 HR HR960558A patent/HRP960558B1/xx not_active IP Right Cessation
- 1996-11-25 RO RO96-02223A patent/RO119782B1/ro unknown
- 1996-11-27 CU CU1996111A patent/CU22774A3/es not_active IP Right Cessation
- 1996-11-29 DE DE59609501T patent/DE59609501D1/de not_active Expired - Lifetime
- 1996-11-29 DK DK96119134T patent/DK0780390T3/da active
- 1996-11-29 PT PT96119134T patent/PT780390E/pt unknown
- 1996-11-29 ES ES96119134T patent/ES2179910T3/es not_active Expired - Lifetime
- 1996-11-29 AT AT96119134T patent/ATE221531T1/de active
- 1996-11-29 SI SI9630468T patent/SI0780390T1/xx unknown
- 1996-11-29 EP EP96119134A patent/EP0780390B1/de not_active Expired - Lifetime
- 1996-12-05 US US08/760,543 patent/US5849752A/en not_active Expired - Lifetime
- 1996-12-05 TR TR96/00970A patent/TR199600970A2/xx unknown
- 1996-12-06 IN IN2723DE1996 patent/IN185805B/en unknown
- 1996-12-06 AU AU74216/96A patent/AU708006B2/en not_active Expired
- 1996-12-06 TW TW085115048A patent/TW411340B/zh not_active IP Right Cessation
- 1996-12-06 YU YU65096A patent/YU49485B/sh unknown
- 1996-12-09 NZ NZ299905A patent/NZ299905A/en not_active IP Right Cessation
- 1996-12-09 AR ARP960105569A patent/AR005009A1/es active IP Right Grant
- 1996-12-09 CA CA002192418A patent/CA2192418C/en not_active Expired - Lifetime
- 1996-12-10 IL IL11979596A patent/IL119795A/en not_active IP Right Cessation
- 1996-12-10 BG BG101043A patent/BG62258B1/bg unknown
- 1996-12-10 ID IDP963684A patent/ID22625A/id unknown
- 1996-12-10 JP JP34450296A patent/JP4104687B2/ja not_active Expired - Lifetime
- 1996-12-10 CO CO96064770A patent/CO4480105A1/es unknown
- 1996-12-10 SG SG1996011612A patent/SG47201A1/en unknown
- 1996-12-10 PL PL96317415A patent/PL184885B1/pl unknown
- 1996-12-11 ZA ZA9610405A patent/ZA9610405B/xx unknown
- 1996-12-11 SK SK1591-96A patent/SK282805B6/sk not_active IP Right Cessation
- 1996-12-11 NO NO19965298A patent/NO306725B1/no not_active IP Right Cessation
- 1996-12-11 BR BR9605968A patent/BR9605968A/pt not_active IP Right Cessation
- 1996-12-11 KR KR1019960064345A patent/KR100525146B1/ko not_active Expired - Lifetime
- 1996-12-11 CZ CZ19963646A patent/CZ288657B6/cs not_active IP Right Cessation
- 1996-12-11 SA SA96170492A patent/SA96170492B1/ar unknown
- 1996-12-11 RU RU96123410/04A patent/RU2162468C2/ru active
- 1996-12-11 EE EE9600201A patent/EE03474B1/xx unknown
- 1996-12-11 MY MYPI96005214A patent/MY117492A/en unknown
- 1996-12-11 UA UA96124628A patent/UA35638C2/uk unknown
- 1996-12-12 SV SV1996000109A patent/SV1996000109A/es active IP Right Grant
- 1996-12-12 HU HU9603428A patent/HU226521B1/hu unknown
- 1996-12-12 CN CN96123220A patent/CN1061348C/zh not_active Expired - Lifetime
-
2002
- 2002-12-05 NL NL300109C patent/NL300109I1/nl unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2303768A1 (es) * | 2006-09-08 | 2008-08-16 | Quimica Sintentica, S.A. | Nueva forma cristalina de moxifloxacino clorhidrato. |
| ES2303768B1 (es) * | 2006-09-08 | 2009-06-05 | Quimica Sintetica, S.A. | Nueva forma cristalina de moxifloxacino clorhidrato. |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2179910T3 (es) | Modificacion cristalina del cdch, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen. | |
| TR200302214T4 (tr) | Psoriasis tedavisi için kullanilan pteridine bileşkenleri | |
| PT750618E (pt) | Derivados de oxazolidinona e composicoes farmaceuticas que os contem | |
| GB2303629B (en) | Hydroxamic acids and their use as metalloproteinase inhibitors | |
| DE69932835D1 (de) | Medizinische aerosolzubereitung | |
| ATE554750T1 (de) | Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen | |
| ES2058411T3 (es) | Sustancia fr 901228 y su preparacion. | |
| ES2055860T3 (es) | Derivados 2-aminopirimidinona. | |
| BRPI9917007B8 (pt) | azabicicloalcanos como moduladores de ccr5, composição farmacêutica contendo os mesmos, bem como seu uso | |
| PT1412384E (pt) | Formulação estável de glp-1 modificado | |
| NO971889L (no) | Forbindelser og sammensetninger for levering av aktive midler | |
| ES2142798T3 (es) | Derivados de 3-amido pirazol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. | |
| SE9904505D0 (sv) | Novel compounds | |
| EA199900991A1 (ru) | Медицинские аэрозольные препараты | |
| BR0012610A (pt) | Novo derivado de difenilpiperidina | |
| BR0111678A (pt) | Composições medicinais contendo derivados de propenona | |
| BR0010983A (pt) | Preparações para a aplicação de agentes antiinflamatórios | |
| ATE253359T1 (de) | Antithrombotische mittel | |
| DE59914183D1 (de) | Abgabeeinrichtung für eine zusammensetzung einer pharmazeutisch wirksamen substanz | |
| BR9713044A (pt) | Composto, uso de um composto, processo para sua preparação,e, formulação farmacêutica. | |
| ES542061A0 (es) | Un procedimiento para la preparacion de (r)-4-amino-n-(1-fe-niletil)benzamida,(s)-4-amino-n-(1-feniletil)benzamida,o unasal de las mismas | |
| IT1291278B1 (it) | Preparazione farmaceutica a base di nimesulide per uso topico | |
| AR008154A1 (es) | Acido (s)-7-[(4,4'-bipiperidin-1-il)carbonil]-2,3,4,5-tetrahidro-4-metil- -3-oxo-1h-1,4-benzodiazepina-2-acetico, como hidrocloruro del mismo, unacomposicion farmaceutica que lo comprende, el uso del mismo y un procedimiento para su preparacion. | |
| ES2053679T3 (es) | Embonato de azelastina, procedimiento para su preparacion y preparados farmaceuticos que contienen embonato de azelastina como principio activo. | |
| TR200100906T2 (tr) | Trombin inhibitörleri olarak benzamid türevleri |