ES2173919T3 - Superoxido dismutasa-4. - Google Patents

Superoxido dismutasa-4.

Info

Publication number
ES2173919T3
ES2173919T3 ES94923172T ES94923172T ES2173919T3 ES 2173919 T3 ES2173919 T3 ES 2173919T3 ES 94923172 T ES94923172 T ES 94923172T ES 94923172 T ES94923172 T ES 94923172T ES 2173919 T3 ES2173919 T3 ES 2173919T3
Authority
ES
Spain
Prior art keywords
polypeptide
sod
polypeptides
nucleic acid
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94923172T
Other languages
English (en)
Spanish (es)
Inventor
Guo-Liang Yu
Craig A Rosen
Claire M Fraser
Jeannine D Gocayne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Application granted granted Critical
Publication of ES2173919T3 publication Critical patent/ES2173919T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0089Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES94923172T 1994-04-11 1994-05-31 Superoxido dismutasa-4. Expired - Lifetime ES2173919T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/225,757 US5506133A (en) 1994-04-11 1994-04-11 Superoxide dismutase-4

Publications (1)

Publication Number Publication Date
ES2173919T3 true ES2173919T3 (es) 2002-11-01

Family

ID=22846108

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94923172T Expired - Lifetime ES2173919T3 (es) 1994-04-11 1994-05-31 Superoxido dismutasa-4.

Country Status (13)

Country Link
US (3) US5506133A (de)
EP (2) EP0775199B1 (de)
JP (2) JPH09511648A (de)
CN (2) CN1073154C (de)
AT (1) ATE215599T1 (de)
AU (1) AU683286B2 (de)
CA (1) CA2187635A1 (de)
DE (1) DE69430326T2 (de)
DK (1) DK0775199T3 (de)
ES (1) ES2173919T3 (de)
PT (1) PT775199E (de)
WO (1) WO1995027781A1 (de)
ZA (1) ZA944039B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672509A (en) * 1993-08-25 1997-09-30 Pfizer Inc. hPDE IV-C: a human phosphodiesterase IV isozyme
US5506133A (en) * 1994-04-11 1996-04-09 Human Genome Sciences, Inc. Superoxide dismutase-4
US20060223077A1 (en) * 1997-06-06 2006-10-05 Human Genome Sciences, Inc. 207 human secreted proteins
FR2792000B1 (fr) * 1999-04-08 2003-04-11 Centre Nat Rech Scient Procede de cartographie d'une molecule d'adn comprenant une etape d'amplification ad infinitum
WO2005069938A2 (en) * 2004-01-20 2005-08-04 The Regents Of The University Of California Extracellular superoxide dismutase (ec-sod) gene delivery to prevent oxidative injury
DE102007010785A1 (de) * 2007-03-02 2008-09-04 Henkel Ag & Co. Kgaa Verwendung von Superoxid-Dismutasen in Wasch- und Reinigungsmitteln
KR102593542B1 (ko) * 2021-06-10 2023-10-26 씨제이제일제당 주식회사 슈퍼옥사이드 디스뮤테이즈 1 변이체 및 이를 이용한 글루타치온 또는 그 유도체의 생산방법

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252476A (en) * 1983-10-03 1993-10-12 Chiron Corporation Superoxide dismutase cloning and expression in microorganisms
US5162217A (en) * 1984-08-27 1992-11-10 Bio-Technology General Corp. Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda PL promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof
US5242794A (en) * 1984-12-13 1993-09-07 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US5248603A (en) * 1985-09-03 1993-09-28 Symbicom Aktiebolag Superoxide dismutase
JPS62103026A (ja) * 1985-10-28 1987-05-13 Nikken Food Kk Sod活性剤およびその製造法
US4976959A (en) * 1986-05-12 1990-12-11 Burroughs Wellcome Co. T-PA and SOD in limiting tissue damage
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
JPS6377822A (ja) * 1986-09-18 1988-04-08 Ube Ind Ltd 臓器機能改善剤
ATE132902T1 (de) * 1987-03-14 1996-01-15 Boehringer Ingelheim Int Humane mangan-superoxiddismutase (hmn-sod)
JPS63313581A (ja) * 1987-06-16 1988-12-21 Ube Ind Ltd 修飾ス−パ−オキシドジスムタ−ゼ
JPH02156884A (ja) * 1988-12-10 1990-06-15 Hagiwara Yoshihide ポリペプチド及びその製造方法
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5360729A (en) * 1989-11-07 1994-11-01 Bio-Technology General Corp. Method for purification of recombinant copper/zinc (CU-ZN) superoxide dismutase from bacteria or eucaryotic cells
IL96136A (en) * 1989-11-07 2000-12-06 Bio Technology General Corp Use of hydrophobic chromatography in a method for purification of copper-zinc superoxide dismutase from cells containing same
US5219737A (en) 1990-03-27 1993-06-15 Kikkoman Corporation Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase
JPH04108379A (ja) * 1990-08-28 1992-04-09 Suntory Ltd 新規スーパーオキサイドディスムターゼ
AU8947791A (en) * 1990-11-01 1992-05-26 Scripps Research Institute, The Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions
JPH04248984A (ja) * 1991-02-05 1992-09-04 Kuraray Co Ltd スーパーオキシドジスムターゼ誘導体およびその製造方法
JPH04312533A (ja) * 1991-04-09 1992-11-04 Nippon Kayaku Co Ltd 脳虚血症治療剤
JPH04327541A (ja) * 1991-04-23 1992-11-17 Nippon Kayaku Co Ltd 拒絶反応による移植臓器障害治療剤
US5506133A (en) * 1994-04-11 1996-04-09 Human Genome Sciences, Inc. Superoxide dismutase-4

Also Published As

Publication number Publication date
US6635252B2 (en) 2003-10-21
CN1332240A (zh) 2002-01-23
JPH09511648A (ja) 1997-11-25
DE69430326T2 (de) 2002-11-07
US5506133A (en) 1996-04-09
EP0775199A4 (de) 1997-12-03
CA2187635A1 (en) 1995-10-19
EP0775199A1 (de) 1997-05-28
US5871729A (en) 1999-02-16
US20020081288A1 (en) 2002-06-27
WO1995027781A1 (en) 1995-10-19
EP1158046A1 (de) 2001-11-28
CN1073154C (zh) 2001-10-17
AU683286B2 (en) 1997-11-06
JP2002085082A (ja) 2002-03-26
ZA944039B (en) 1995-12-08
AU7312394A (en) 1995-10-30
ATE215599T1 (de) 2002-04-15
EP0775199B1 (de) 2002-04-03
CN1152337A (zh) 1997-06-18
DK0775199T3 (da) 2002-06-03
PT775199E (pt) 2002-08-30
DE69430326D1 (de) 2002-05-08

Similar Documents

Publication Publication Date Title
ATE337403T1 (de) Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen
DE69428214D1 (de) Transformierender wachstumsfaktor alpha h1
ATE277078T1 (de) N-terminal modifizierte polypeptide, und herstellungsprozess
ES2155819T3 (es) Inmunoglobulinas hibridas.
ATE159297T1 (de) Expression von menschlichen serumalbumin in methylotrophischen hefen
DE3855084D1 (de) Herstellung und Reinigung eines Proteins, das mit einem Bindungsprotein fusioniert ist
CA2075974A1 (en) Totally synthetic affinity reagents
ATE256182T1 (de) Neuartiges p- selectin ligandenprotein
DE69130466D1 (de) Basen-Tumorzellen Behandlungsverfahren
ZA903939B (en) Substituted(quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides,processes for their preparation and their use in medicaments
ES2173919T3 (es) Superoxido dismutasa-4.
WO2000015659A3 (en) Stomach polypeptide zsig28
DE59608422D1 (de) Verfahren zur Herstellung von Poly(diorganosiloxanen), Mischungen, enthaltend diese Poly(diorganosiloxane) und deren Verwendung
ATE331032T1 (de) Glutamine: fructose-6-phosphat amidotransferase (gfat), ihre herstellung und verwendung
CA2128215A1 (en) Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
EP1757311A3 (de) Verfahren und Zusammensetzungen zur Verlängerung der Entsorgungshalbwertszeit von biowirksamen Verbindungen
ATE133421T1 (de) Verfahren zur herstellung von rekombinantem humaninterferon-beta in reiner form
ATE443141T1 (de) Aktivitätsabhänginger neurotropischer faktor iii(adnf iii)
ATA181893A (de) Verfahren zur herstellung von isocyansäure aus cyanursäure
ATE53384T1 (de) 3-mercapto-2-oxo-1-pyrrolidinessigsaeurederivate verfahren zur herstellung und pharmazeutische zusammensetzungen die sie enthalten.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 775199

Country of ref document: ES