ATE443141T1 - Aktivitätsabhänginger neurotropischer faktor iii(adnf iii) - Google Patents
Aktivitätsabhänginger neurotropischer faktor iii(adnf iii)Info
- Publication number
- ATE443141T1 ATE443141T1 AT98907407T AT98907407T ATE443141T1 AT E443141 T1 ATE443141 T1 AT E443141T1 AT 98907407 T AT98907407 T AT 98907407T AT 98907407 T AT98907407 T AT 98907407T AT E443141 T1 ATE443141 T1 AT E443141T1
- Authority
- AT
- Austria
- Prior art keywords
- iii
- adnf iii
- adnf
- activity dependent
- iii polypeptides
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 2
- 230000001419 dependent effect Effects 0.000 title 1
- 239000003076 neurotropic agent Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 102100022385 Activity-dependent neuroprotector homeobox protein Human genes 0.000 abstract 2
- 101710170468 Activity-dependent neuroprotector homeobox protein Proteins 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 101710091045 Envelope protein Proteins 0.000 abstract 1
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 abstract 1
- HOKKHZGPKSLGJE-UHFFFAOYSA-N N-methyl-D-aspartic acid Natural products CNC(C(O)=O)CC(O)=O HOKKHZGPKSLGJE-UHFFFAOYSA-N 0.000 abstract 1
- 101710188315 Protein X Proteins 0.000 abstract 1
- 102100021696 Syncytin-1 Human genes 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 108010027834 activity-dependent neurotrophic factor Proteins 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000003492 excitotoxic effect Effects 0.000 abstract 1
- 231100000063 excitotoxicity Toxicity 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000004776 neurological deficiency Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- CFMYXEVWODSLAX-QOZOJKKESA-N tetrodotoxin Chemical compound O([C@@]([C@H]1O)(O)O[C@H]2[C@@]3(O)CO)[C@H]3[C@@H](O)[C@]11[C@H]2[C@@H](O)N=C(N)N1 CFMYXEVWODSLAX-QOZOJKKESA-N 0.000 abstract 1
- 229950010357 tetrodotoxin Drugs 0.000 abstract 1
- CFMYXEVWODSLAX-UHFFFAOYSA-N tetrodotoxin Natural products C12C(O)NC(=N)NC2(C2O)C(O)C3C(CO)(O)C1OC2(O)O3 CFMYXEVWODSLAX-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Lock And Its Accessories (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3740497P | 1997-02-07 | 1997-02-07 | |
| PCT/US1998/002485 WO1998035042A2 (en) | 1997-02-07 | 1998-02-06 | Activity dependent neurotrophic factor iii (adnf iii) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443141T1 true ATE443141T1 (de) | 2009-10-15 |
Family
ID=21894162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98907407T ATE443141T1 (de) | 1997-02-07 | 1998-02-06 | Aktivitätsabhänginger neurotropischer faktor iii(adnf iii) |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP2172478A3 (de) |
| JP (1) | JP4649602B2 (de) |
| AT (1) | ATE443141T1 (de) |
| AU (1) | AU737406B2 (de) |
| CA (1) | CA2279231C (de) |
| DE (1) | DE69841160D1 (de) |
| DK (1) | DK0966533T3 (de) |
| ES (1) | ES2331595T3 (de) |
| PT (1) | PT966533E (de) |
| WO (1) | WO1998035042A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613740B1 (en) | 1997-02-07 | 2003-09-02 | Ramot University Authority For Applied Research And Industrial Development Ltd. | Activity dependent neurotrophic factor III (ADNF III) |
| US6933277B2 (en) | 1999-03-12 | 2005-08-23 | The United States Of America As Represented By The Department Of Health And Human Services | Prevention of fetal alcohol syndrome and neuronal cell death with ADNF polypeptides |
| US6649411B2 (en) * | 1999-07-30 | 2003-11-18 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of inhibiting cancer cells with ADNF III antisense oligonucleotides |
| ATE266044T1 (de) * | 1999-08-18 | 2004-05-15 | Univ Ramot | Oral wirksame peptide, die zellschädigung und zelltod verhindern |
| US7384908B1 (en) | 1999-08-18 | 2008-06-10 | National Institute Of Health | Orally active peptides that prevent cell damage and death |
| DE60107416T2 (de) | 2000-05-31 | 2005-12-01 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion |
| WO2004080957A2 (en) * | 2003-03-12 | 2004-09-23 | Ramot At Tel Aviv University Ltd. | Use of adnf polypeptides for treating anxiety and depression |
| JP4878551B2 (ja) | 2004-04-08 | 2012-02-15 | 貞和 相磯 | 運動ニューロン疾患治療薬 |
| AU2006227528B2 (en) * | 2005-03-23 | 2011-05-26 | Allon Therapeutics, Inc. | Use of ADNF polypeptides for treating peripheral neurotoxicity |
| CA2638827A1 (en) | 2006-02-24 | 2007-08-30 | Illana Gozes | Protection of the retina against laser injury by adnf peptides such as nap and sal |
| WO2008084483A1 (en) | 2007-01-11 | 2008-07-17 | Ramot At Tel Aviv University Ltd. | Novel therapeutics based on tau/microtubule dynamics |
| WO2011021186A1 (en) | 2009-08-17 | 2011-02-24 | Ramot At Tel-Aviv University, Ltd. | Nap alpha-aminoisobutyric acid analog with neuroprotective activity |
| EP2521919B1 (de) | 2010-01-06 | 2015-03-04 | Ramot at Tel Aviv University, Ltd. | Verfahren zur diagnose und überwachung von schizophrenie und tauopathien |
| US20130053320A1 (en) | 2010-02-12 | 2013-02-28 | Ramot At Tel-Aviv University, Ltd. | Treatment of anemia by adnp and adnf polypeptides |
| WO2012015910A2 (en) | 2010-07-28 | 2012-02-02 | Allon Therapeutics Inc. | Use of adnf polypeptides for treating neurodegenerative diseases |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| WO2019023247A1 (en) | 2017-07-25 | 2019-01-31 | Immutics, Inc. | TREATMENT OF CANCER BY BLOCKING THE INTERACTION OF TIM-3 AND ITS LIGAND |
| JP2022523333A (ja) | 2019-01-30 | 2022-04-22 | トゥルーバインディング，インコーポレイテッド | 抗ｇａｌ３抗体およびその使用 |
| EP4157338A4 (de) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | Verfahren zur behandlung von entzündungskrankheiten durch galectin-3-blockierung |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3740497A (en) | 1971-06-29 | 1973-06-19 | G Daniell | Artificial line bridge subscriber dial long line equipment tester |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4254082A (en) | 1978-06-12 | 1981-03-03 | Miles Laboratories, Inc. | Specific binding-adsorbent assay test means |
| US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US4517288A (en) | 1981-01-23 | 1985-05-14 | American Hospital Supply Corp. | Solid phase system for ligand assay |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| CH652145A5 (de) | 1982-01-22 | 1985-10-31 | Sandoz Ag | Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen. |
| JPS58215453A (ja) | 1982-06-09 | 1983-12-14 | Toray Silicone Co Ltd | 室温硬化後塗装可能なオルガノポリシロキサン組成物 |
| US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4634666A (en) | 1984-01-06 | 1987-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | Human-murine hybridoma fusion partner |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5169939A (en) | 1985-05-21 | 1992-12-08 | Massachusetts Institute Of Technology & Pres. & Fellows Of Harvard College | Chimeric antibodies |
| CA1291031C (en) | 1985-12-23 | 1991-10-22 | Nikolaas C.J. De Jaeger | Method for the detection of specific binding agents and their correspondingbindable substances |
| IL84285A (en) | 1986-10-27 | 1993-03-15 | Int Genetic Engineering | Chimeric antibody with specificity to human tumor antigen |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5001065A (en) | 1987-05-27 | 1991-03-19 | Cetus Corporation | Human cell line and triomas, antibodies, and transformants derived therefrom |
| US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5202238A (en) | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5231026A (en) | 1987-12-31 | 1993-07-27 | Tanox Biosystems, Inc. | DNA encoding murine-human chimeric antibodies specific for antigenic epitopes of IgE present on the extracellular segment of the membrane domain of membrane-bound IgE |
| US4975369A (en) | 1988-04-21 | 1990-12-04 | Eli Lilly And Company | Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen |
| US5292867A (en) | 1988-11-16 | 1994-03-08 | Tanox Biosystems, Inc. | Chimeric monoclonal antibodies which bind to the extracellular segment of the membrane-bound domain of a human membrane-bound immunoglobulin |
| IL94872A (en) | 1989-06-30 | 1995-03-30 | Oncogen | Monoclonal or chimeric antibodies reactive with human carcinomas, recombinant proteins comprising their antigen binding region, pharmaceutical compositions and kits comprising said antibodies and methods for imaging human carcinoma using same |
| US5075431A (en) | 1989-07-26 | 1991-12-24 | City Of Hope | Chimeric anti-CEA antibody |
| US5081235A (en) | 1989-07-26 | 1992-01-14 | City Of Hope | Chimeric anti-cea antibody |
| US6174862B1 (en) * | 1991-04-22 | 2001-01-16 | Ramot University Authority For Applied Research And Industrial Development, Ltd. | Neurotrophic peptides of activity dependent neurotrophic factor |
| EP0662092B1 (de) * | 1991-04-22 | 2005-03-23 | THE UNITED STATES OF AMERICA, represented by the SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Aktivitätsabhängiger neurotropher faktor |
| GB9125979D0 (en) | 1991-12-06 | 1992-02-05 | Wellcome Found | Antibody |
| US5472693A (en) | 1993-02-16 | 1995-12-05 | The Dow Chemical Company | Family of anti-carcinoembryonic antigen chimeric antibodies |
| US5506132A (en) | 1993-07-28 | 1996-04-09 | Sandoz Pharmaceuticals Corporation | Human antibodies against varicella-zoster virus |
| US5426039A (en) | 1993-09-08 | 1995-06-20 | Bio-Rad Laboratories, Inc. | Direct molecular cloning of primer extended DNA containing an alkane diol |
-
1998
- 1998-02-06 AT AT98907407T patent/ATE443141T1/de active
- 1998-02-06 JP JP53498298A patent/JP4649602B2/ja not_active Expired - Fee Related
- 1998-02-06 EP EP09170287A patent/EP2172478A3/de not_active Withdrawn
- 1998-02-06 PT PT98907407T patent/PT966533E/pt unknown
- 1998-02-06 WO PCT/US1998/002485 patent/WO1998035042A2/en not_active Ceased
- 1998-02-06 DE DE69841160T patent/DE69841160D1/de not_active Expired - Lifetime
- 1998-02-06 ES ES98907407T patent/ES2331595T3/es not_active Expired - Lifetime
- 1998-02-06 CA CA2279231A patent/CA2279231C/en not_active Expired - Fee Related
- 1998-02-06 DK DK98907407T patent/DK0966533T3/da active
- 1998-02-06 EP EP98907407A patent/EP0966533B1/de not_active Expired - Lifetime
- 1998-02-06 AU AU63222/98A patent/AU737406B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69841160D1 (de) | 2009-10-29 |
| DK0966533T3 (da) | 2010-01-04 |
| JP4649602B2 (ja) | 2011-03-16 |
| ES2331595T3 (es) | 2010-01-08 |
| EP0966533B1 (de) | 2009-09-16 |
| EP2172478A2 (de) | 2010-04-07 |
| PT966533E (pt) | 2010-01-26 |
| CA2279231C (en) | 2013-11-26 |
| EP0966533A1 (de) | 1999-12-29 |
| JP2001522228A (ja) | 2001-11-13 |
| AU737406B2 (en) | 2001-08-16 |
| AU6322298A (en) | 1998-08-26 |
| EP2172478A3 (de) | 2010-07-28 |
| WO1998035042A8 (en) | 2006-11-09 |
| CA2279231A1 (en) | 1998-08-13 |
| WO1998035042A2 (en) | 1998-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0966533 Country of ref document: EP |
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| EEFA | Change of the company name |