CY1110371T1 - ΑΝΑΣΥΝΔΥΑΣΜΕΝΑ ΑΝΤΙΣΩΜΑΤΑ ΕΠΙΛΕΚΤΙΚΑ ΤΩΝ ΑΚΡΩΝ ΤΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, DNA ΠΟΥ ΤΑ ΚΩΔΙΚΟΠΟΙΟΥΝ ΚΑΙ ΜΕΘΟΔΟΙ ΧΡΗΣΕΩΣ ΤΟΥΣ - Google Patents

ΑΝΑΣΥΝΔΥΑΣΜΕΝΑ ΑΝΤΙΣΩΜΑΤΑ ΕΠΙΛΕΚΤΙΚΑ ΤΩΝ ΑΚΡΩΝ ΤΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, DNA ΠΟΥ ΤΑ ΚΩΔΙΚΟΠΟΙΟΥΝ ΚΑΙ ΜΕΘΟΔΟΙ ΧΡΗΣΕΩΣ ΤΟΥΣ

Info

Publication number
CY1110371T1
CY1110371T1 CY20081101230T CY081101230T CY1110371T1 CY 1110371 T1 CY1110371 T1 CY 1110371T1 CY 20081101230 T CY20081101230 T CY 20081101230T CY 081101230 T CY081101230 T CY 081101230T CY 1110371 T1 CY1110371 T1 CY 1110371T1
Authority
CY
Cyprus
Prior art keywords
amyloid
recombinant
methods
dna coding
selective antibodies
Prior art date
Application number
CY20081101230T
Other languages
English (en)
Inventor
Daniel G Chain
Original Assignee
Intellect Neurosciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21918670&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110371(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intellect Neurosciences, Inc. filed Critical Intellect Neurosciences, Inc.
Publication of CY1110371T1 publication Critical patent/CY1110371T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/025—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a parvovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

DNA που κωδικοποιεί ένα μόριο ανασυνδυασμένου αντισώματος επιλεκτικού των άκρων ενός πεπτιδίου αμυλοειδούς-β, φαρμακευτικές συνθέσεις του και μία μέθοδος για την πρόληψη ή την αναστολή της εξελίξεως της νόσου του Alzheimer δι' εισαγωγής ενός τέτοιου μορίου DNA σε κύτταρα εγκεφάλου για την έκφραση του μορίου ανασυνδυασμένου αντισώματος και την αποτροπή της συσσωρεύσεως πεπτιδίων αμυλοειδούς-β στο εγκεφαλονωτιαίο υγρό.
CY20081101230T 1997-04-09 2008-10-30 ΑΝΑΣΥΝΔΥΑΣΜΕΝΑ ΑΝΤΙΣΩΜΑΤΑ ΕΠΙΛΕΚΤΙΚΑ ΤΩΝ ΑΚΡΩΝ ΤΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, DNA ΠΟΥ ΤΑ ΚΩΔΙΚΟΠΟΙΟΥΝ ΚΑΙ ΜΕΘΟΔΟΙ ΧΡΗΣΕΩΣ ΤΟΥΣ CY1110371T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4185097P 1997-04-09 1997-04-09
EP98918035A EP0994728B1 (en) 1997-04-09 1998-04-09 Recombinant antibodies specific for beta-amyloid ends, dna encoding and methods of use thereof

Publications (1)

Publication Number Publication Date
CY1110371T1 true CY1110371T1 (el) 2015-04-29

Family

ID=21918670

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081101230T CY1110371T1 (el) 1997-04-09 2008-10-30 ΑΝΑΣΥΝΔΥΑΣΜΕΝΑ ΑΝΤΙΣΩΜΑΤΑ ΕΠΙΛΕΚΤΙΚΑ ΤΩΝ ΑΚΡΩΝ ΤΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, DNA ΠΟΥ ΤΑ ΚΩΔΙΚΟΠΟΙΟΥΝ ΚΑΙ ΜΕΘΟΔΟΙ ΧΡΗΣΕΩΣ ΤΟΥΣ

Country Status (16)

Country Link
US (2) US20090069258A1 (el)
EP (3) EP2305709A1 (el)
JP (3) JP3816111B2 (el)
CN (1) CN1177616C (el)
AT (1) ATE402717T1 (el)
AU (1) AU743827B2 (el)
CA (1) CA2286305A1 (el)
CY (1) CY1110371T1 (el)
DE (1) DE69839808D1 (el)
DK (1) DK0994728T3 (el)
ES (1) ES2312185T3 (el)
IL (1) IL132262A (el)
NZ (1) NZ337765A (el)
PT (1) PT994728E (el)
SI (1) SI0994728T1 (el)
WO (1) WO1998044955A1 (el)

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AU7103498A (en) 1998-10-30
EP0994728B1 (en) 2008-07-30
DK0994728T3 (da) 2008-12-01
CN1254294A (zh) 2000-05-24
EP0994728A4 (en) 2001-11-28
US20110027279A1 (en) 2011-02-03
IL132262A (en) 2009-11-18
EP2305709A1 (en) 2011-04-06
ATE402717T1 (de) 2008-08-15
CA2286305A1 (en) 1998-10-15
ES2312185T3 (es) 2009-02-16
JP2002503092A (ja) 2002-01-29
EP0994728A1 (en) 2000-04-26
CN1177616C (zh) 2004-12-01
EP2006303A1 (en) 2008-12-24
PT994728E (pt) 2008-11-11
NZ337765A (en) 2001-09-28
JP3816111B2 (ja) 2006-08-30
WO1998044955A1 (en) 1998-10-15
SI0994728T1 (sl) 2009-02-28
US20090069258A1 (en) 2009-03-12
DE69839808D1 (de) 2008-09-11
AU743827B2 (en) 2002-02-07

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