ES2173884T3 - Preparacion de ubterneduis beta-metilcarbapenemo. - Google Patents

Preparacion de ubterneduis beta-metilcarbapenemo.

Info

Publication number
ES2173884T3
ES2173884T3 ES93307322T ES93307322T ES2173884T3 ES 2173884 T3 ES2173884 T3 ES 2173884T3 ES 93307322 T ES93307322 T ES 93307322T ES 93307322 T ES93307322 T ES 93307322T ES 2173884 T3 ES2173884 T3 ES 2173884T3
Authority
ES
Spain
Prior art keywords
beta
ubterneduis
metilcarbapenemo
preparation
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93307322T
Other languages
English (en)
Inventor
Woog-Baeg Choi
Ichiro Shinkai
Guy R Humphrey
Andrew S Thompson
Paul J Reider
Ralph P Volante
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of ES2173884T3 publication Critical patent/ES2173884T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION SE DIRIGE A UN PROCESO PARA FABRICAR UN PRODUCTO INTERMEDIO PARA EL CARBAPENEM DE BETA-METIL DE LA FORMULA VI A PARTIR DE UN COMPUESTO DE LA FORMULA I EN DONDE R Y P'' SON GRUPOS PROTECTORES, R1 ES UN ESTER DE ACIDO METILMALONICO Y NU ES UN GRUPO NUCLEOFILICO. TAMBIEN SE PRESENTAN PRODUCTOS INTERMEDIOS PARA ESTE PROCESO.
ES93307322T 1992-09-18 1993-09-16 Preparacion de ubterneduis beta-metilcarbapenemo. Expired - Lifetime ES2173884T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94718692A 1992-09-18 1992-09-18

Publications (1)

Publication Number Publication Date
ES2173884T3 true ES2173884T3 (es) 2002-11-01

Family

ID=25485687

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93307322T Expired - Lifetime ES2173884T3 (es) 1992-09-18 1993-09-16 Preparacion de ubterneduis beta-metilcarbapenemo.

Country Status (24)

Country Link
US (2) US6242596B1 (es)
EP (1) EP0589626B1 (es)
JP (1) JP3252032B2 (es)
CN (2) CN1066438C (es)
AR (1) AR000394A2 (es)
AT (1) ATE214048T1 (es)
AU (1) AU667571B2 (es)
CA (1) CA2106248A1 (es)
CZ (1) CZ286267B6 (es)
DE (1) DE69331650T2 (es)
DK (1) DK0589626T3 (es)
ES (1) ES2173884T3 (es)
FI (1) FI951212A0 (es)
HK (1) HK1008336A1 (es)
HR (1) HRP931199B1 (es)
MX (1) MX9305715A (es)
PT (1) PT589626E (es)
RO (1) RO116087B1 (es)
RU (1) RU2130927C1 (es)
SI (1) SI9300486B (es)
SK (1) SK282164B6 (es)
TW (1) TW406073B (es)
UA (1) UA50705C2 (es)
WO (1) WO1994006764A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1061233C (zh) * 1996-12-13 2001-01-31 高琳 一种保健口服液及其生产工艺
KR100335848B1 (ko) * 2000-03-31 2002-05-08 윤재승 아제티디논 유도체, 그 제조방법 및 이를 이용한1-β-알킬아제티디논의 제조방법
US6625203B2 (en) * 2001-04-30 2003-09-23 Interdigital Technology Corporation Fast joint detection
EP1878829A1 (de) 2006-07-12 2008-01-16 Papierfabriken Cham-Tenero AG Beschichtetes Trägerpapier

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001705A1 (en) * 1980-11-13 1982-05-27 Takeda Chemical Industries Ltd 4-substituted-2-oxoazetidine derivatives and process for their preparation
AU548727B2 (en) * 1981-03-12 1986-01-02 Gruppo Lepetit S.P.A. Beta-lactam acetic acid derivatives
US4576747A (en) * 1984-05-07 1986-03-18 The Upjohn Company Isocyanato-azetidinediones
DE3566888D1 (en) * 1984-10-04 1989-01-26 Ciba Geigy Ag Silanes, process for their preparation and their use
DE3879791T2 (de) 1987-07-17 1993-10-14 Merck & Co Inc 4-Substituierte 3-Oxobutanoat-Esterderivate.
EP0308867B1 (en) * 1987-09-22 1995-07-26 Shionogi Seiyaku Kabushiki Kaisha Alkenylsilylazetidinone intermediates for carbapenems
US4992545A (en) * 1989-09-20 1991-02-12 Eli Lilly And Company Process for preparing 4-substituted azetidinones
DE69231883T2 (de) * 1991-12-09 2001-10-04 Takasago Perfumery Co Ltd 4-(1,1-Dialkoxycarbonyl-Alkyl)Azetidin-2-on-Derivate zur Herstellung von 4-(1-Carboxy-Alkyl)Azetidin-2-on-Derivaten

Also Published As

Publication number Publication date
RU95108544A (ru) 1997-01-10
AR000394A2 (es) 1997-06-18
MX9305715A (es) 1994-03-31
TW406073B (en) 2000-09-21
CZ286267B6 (cs) 2000-03-15
AU4743393A (en) 1994-03-24
EP0589626A1 (en) 1994-03-30
CN1066438C (zh) 2001-05-30
EP0589626B1 (en) 2002-03-06
SI9300486B (sl) 2003-02-28
AU667571B2 (en) 1996-03-28
JP3252032B2 (ja) 2002-01-28
DK0589626T3 (da) 2002-04-02
SK34995A3 (en) 1995-08-09
US6242596B1 (en) 2001-06-05
SK282164B6 (sk) 2001-11-06
WO1994006764A1 (en) 1994-03-31
RO116087B1 (ro) 2000-10-30
RU2130927C1 (ru) 1999-05-27
CN1092763A (zh) 1994-09-28
FI951212A (fi) 1995-03-15
UA50705C2 (uk) 2002-11-15
US5654424A (en) 1997-08-05
SI9300486A (en) 1994-03-31
HRP931199B1 (en) 2003-02-28
DE69331650T2 (de) 2002-08-22
DE69331650D1 (de) 2002-04-11
PT589626E (pt) 2002-07-31
JPH06192220A (ja) 1994-07-12
HRP931199A2 (en) 1995-02-28
HK1008336A1 (en) 1999-05-07
CN1232035A (zh) 1999-10-20
FI951212A0 (fi) 1995-03-15
CN1101397C (zh) 2003-02-12
CZ34695A3 (en) 1995-11-15
ATE214048T1 (de) 2002-03-15
CA2106248A1 (en) 1994-03-19

Similar Documents

Publication Publication Date Title
MX9504381A (es) Derivados de ureido de acidos naftalenfosfonicos y procesos para su preparacion.
ATE260919T1 (de) Zwischenprodukte für die herstellung von pharmazeutischem camptothecin
UY24192A1 (es) Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen
NO932870L (no) Ny fremgangsmaate for fremstilling av 9-amino-6-demetyl-6-deoksyetracykliner
FR2416889A1 (fr) Derives esters de l'acide dihydro-1,4-pyridine-dicarboxylique-3,5, medicaments a base de ces derives et leur procede de production
PL300327A1 (en) Substituted cycolohexane derivatives, method of obtaining them and application of these compounds in treating diseases
ZA95777B (en) Process for making avermectin/zein compositions
EP0030031A3 (en) 6-(1-hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids, a process for preparing the same, an antibiotic pharmaceutical composition comprising the same, intermediates useful in a synthesis of that kind and processes for preparing intermediates suitable for the synthesis of that kind
ES2173884T3 (es) Preparacion de ubterneduis beta-metilcarbapenemo.
NO165073C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 6-hydroxyalkyl-2-(substituert)thio-penem-3-carboxylsyrer
ES543154A0 (es) Metodo de preparar un derivado de acido b-carbolin-3-carbo- xilico
EE03071B1 (et) Karbasolooni derivaadid ja nende saamise protsess
ATE82569T1 (de) Herstellung von chinolincarbonsaeuren.
DE69403541D1 (de) Lacton-Verbindung und Verfahren zu ihrer Herstellung
DE69228541D1 (de) Chinasäurederivate und Verfahren zur Herstellung von Chinasäurederivaten
FI921717A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 4-metoksi-10-(1-hydroksietyyli)-11-okso-1-atsatrisyklo/7.2.0.03,8/-undek-2-eeni-2-karboksyylihappojen asyylioksialkyyliestereiden valmistamiseksi
FR2692263B1 (fr) Procédé de préparation d'esters cycliques d'acides-alpha-hydroxycarboxyliques.
HUT53596A (en) Process for production of derivatives of euantiomer-glutare with diurethicak effect and medical compositions containing them
DE69416018D1 (de) Verfahren zur Herstellung von Alkoxyiminoacetamid-Verbindungen
JPS55111463A (en) Beta-lactam compound and its preparation
MX9204868A (es) Procedimiento para preparar acido 2,5-di-(fenil-amino)-tereftalico y sus esteres di-alquilicos con alta pureza.
IT8149767A0 (it) Procedimento per la produzione di acido tereftalico da tereftalato dimetilico quale prodotto intermedio
ES2104363T3 (es) Proceso para la preparacion de acido aminometanofosfonico.
ATE156819T1 (de) Verfahren zur herstellung einer oxazolidincarbon säure nützlich für die herstellung von therapeutischen taxoiden
FR2396001A1 (fr) Derives a-acetyleniques et a-vinyliques d'amino-acides utiles comme medicaments et leur procede de preparation

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 589626

Country of ref document: ES