ES2166741A1 - Procedimiento de potenciacion de la actividad antitumoral de una sustancia que contiene amigdalina, composicion que contiene la sustancia que contiene amigdalina potenciada, procedimiento para evaluar la eficacia antitumoral del tratamiento de la sustancia que contiene amigdalina - Google Patents

Procedimiento de potenciacion de la actividad antitumoral de una sustancia que contiene amigdalina, composicion que contiene la sustancia que contiene amigdalina potenciada, procedimiento para evaluar la eficacia antitumoral del tratamiento de la sustancia que contiene amigdalina

Info

Publication number
ES2166741A1
ES2166741A1 ES200100097A ES200100097A ES2166741A1 ES 2166741 A1 ES2166741 A1 ES 2166741A1 ES 200100097 A ES200100097 A ES 200100097A ES 200100097 A ES200100097 A ES 200100097A ES 2166741 A1 ES2166741 A1 ES 2166741A1
Authority
ES
Spain
Prior art keywords
amygdalin
substance
antitumor
assessing
efficacy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200100097A
Other languages
English (en)
Other versions
ES2166741B1 (es
Inventor
Kozo Niwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES2166741A1 publication Critical patent/ES2166741A1/es
Application granted granted Critical
Publication of ES2166741B1 publication Critical patent/ES2166741B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedimiento de potenciación de la actividad antitumoral de una sustancia que contiene amigdalina, composición que contiene la sustancia que contiene amigdalina potenciada, procedimiento para evaluar la eficacia antitumoral del tratamiento de la sustancia que contiene amigdalina y procedimiento para evaluar la sustancia antitumoral que contiene amigdalina. La presente invención consiste en aumentar la eficacia anticancerígena de la semilla de níspero que contiene amigdalina, etc., mediante el tostado con radiación infrarroja, la fermentación con Koji y el recubrimiento con aceite. La invención se refiere a la mayor formación de lípido peróxido en el sistema de irradiación de ácido docosahexanoico con rayos ultravioletas, añadiendo concentraciones crecientes del producto que contiene amigdalina tratado con los procedimientos. Se evalúa y predice que cuanto más lípido peróxido se forme, mayor es la eficacia anticancerígena por vía oral. La invención aplica el procedimiento de esta invencióna la evaluación de la eficacia de sustancias que contienen amigdalina.
ES200100097A 2000-01-17 2001-01-16 Procedimiento de potenciacion de la actividad antitumoral de una sustancia que contiene amigdalina, composicion que contiene la sustancia que contiene amigdalina potenciada, procedimiento para evaluar la eficacia antitumoral del tratamiento de la sustancia que contiene amigdalina Expired - Lifetime ES2166741B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000008337A JP2001199892A (ja) 2000-01-17 2000-01-17 アミグダリン含有物の抗腫瘍活性強化方法、抗腫瘍活性強化アミグダリン含有物を含む組成物、アミグダリン含有物処理の抗腫瘍有効性評価方法、およびアミグダリン含有物の抗腫瘍有効性評価方法

Publications (2)

Publication Number Publication Date
ES2166741A1 true ES2166741A1 (es) 2002-04-16
ES2166741B1 ES2166741B1 (es) 2003-11-16

Family

ID=18536624

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200100097A Expired - Lifetime ES2166741B1 (es) 2000-01-17 2001-01-16 Procedimiento de potenciacion de la actividad antitumoral de una sustancia que contiene amigdalina, composicion que contiene la sustancia que contiene amigdalina potenciada, procedimiento para evaluar la eficacia antitumoral del tratamiento de la sustancia que contiene amigdalina

Country Status (19)

Country Link
US (2) US20010009903A1 (es)
JP (1) JP2001199892A (es)
KR (1) KR20010076279A (es)
CN (1) CN1319431A (es)
AU (1) AU1502101A (es)
CA (1) CA2331167A1 (es)
DE (1) DE10101543A1 (es)
DK (1) DK200100086A (es)
ES (1) ES2166741B1 (es)
FR (1) FR2805746A1 (es)
GB (1) GB2360211A (es)
ID (1) ID29765A (es)
IL (1) IL140900A0 (es)
IS (1) IS5804A (es)
IT (1) ITTO20010028A1 (es)
NL (1) NL1017117C2 (es)
NO (1) NO20010049L (es)
SE (1) SE0100083L (es)
ZA (1) ZA200100377B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3256746B2 (ja) * 2000-03-02 2002-02-12 高知医科大学長 細胞線維化を抑制する組成物及び枇杷核エキスの調製方法
KR100470294B1 (ko) * 2002-08-20 2005-02-05 (주) 한약마을 도인 또는 행인으로부터 아미그달린을 효과적으로 얻는추출방법
GB0402728D0 (en) * 2004-02-07 2004-03-10 Pharming Ltd Pesticides
JP2006197928A (ja) * 2004-12-22 2006-08-03 Yamaguchi Prefecture タケノコ麹及びその製造方法並びにタケノコ醗酵食品及びその製造方法
WO2007001080A1 (ja) * 2005-06-27 2007-01-04 Kagoshima University ビワ葉抽出物を含有する飲食品及び医薬品
CN101190019B (zh) * 2006-11-21 2011-03-09 马玉林 杏仁酱及其制备方法
CN107400150A (zh) * 2017-08-16 2017-11-28 黄山市歙县绿色三潭枇杷生物科技有限公司 一种从枇杷核中提取苦杏仁苷的方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2007414A6 (es) * 1986-09-25 1989-06-16 Kozo Niwa Procedimiento de produccion de productos naturales antioxidantes para fines mediocos.
ES2036496A1 (es) * 1991-08-14 1993-05-16 Kozo Niwa Composicion vegetal de bajo peso molecular compuesta por semilla de cardo mariano.
ES2049189A1 (es) * 1992-06-22 1994-04-01 Niwa Metodo para la produccion de un preparado oleoso.
JPH06227998A (ja) * 1993-01-28 1994-08-16 Sanji Kumai ニトリル配糖体を含有する生薬エキスの制癌活性

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2314800A (en) * 1996-12-05 1998-01-14 Henry Berry & Co Ltd Component assembly machine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2007414A6 (es) * 1986-09-25 1989-06-16 Kozo Niwa Procedimiento de produccion de productos naturales antioxidantes para fines mediocos.
ES2036496A1 (es) * 1991-08-14 1993-05-16 Kozo Niwa Composicion vegetal de bajo peso molecular compuesta por semilla de cardo mariano.
ES2049189A1 (es) * 1992-06-22 1994-04-01 Niwa Metodo para la produccion de un preparado oleoso.
JPH06227998A (ja) * 1993-01-28 1994-08-16 Sanji Kumai ニトリル配糖体を含有する生薬エキスの制癌活性

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NIWA K. et al.: "Anti-cancer effect in vitro and clinical efficacy of a cancer therapeutic containing natural herbs (BG-104), exposed to far infrared-ray heating and fermentation process using Aspergillus oryzae", Oyo Yakuri, Vol. 47, no 5, paginas 465-77, (1994), ISSN: 0300-8533, (resumen), HCAPLUS [en linea]. Columbus, OH (EE.UU.): Chemical Abstracts Service [recuperado el 10.04.2001]. Recuperado de: STN International, Columbus, OH (EE.UU.). No de acceso 1994:49737 *

Also Published As

Publication number Publication date
ITTO20010028A0 (it) 2001-01-16
NL1017117A1 (nl) 2001-07-19
FR2805746A1 (fr) 2001-09-07
IS5804A (is) 2001-07-17
DE10101543A1 (de) 2001-07-19
ZA200100377B (en) 2001-07-18
ID29765A (id) 2001-10-11
NL1017117C2 (nl) 2003-09-30
NO20010049L (no) 2001-07-18
US20010009903A1 (en) 2001-07-26
DK200100086A (da) 2001-07-18
IL140900A0 (en) 2002-02-10
CA2331167A1 (en) 2001-07-17
GB0101181D0 (en) 2001-02-28
KR20010076279A (ko) 2001-08-11
CN1319431A (zh) 2001-10-31
AU1502101A (en) 2001-07-19
SE0100083L (sv) 2001-07-18
GB2360211A (en) 2001-09-19
NO20010049D0 (no) 2001-01-04
JP2001199892A (ja) 2001-07-24
ITTO20010028A1 (it) 2002-07-16
US20020098252A1 (en) 2002-07-25
ES2166741B1 (es) 2003-11-16
SE0100083D0 (sv) 2001-01-12

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