ES2165711T3 - Colorantes de trimetina cianina rigidificada. - Google Patents
Colorantes de trimetina cianina rigidificada.Info
- Publication number
- ES2165711T3 ES2165711T3 ES98963218T ES98963218T ES2165711T3 ES 2165711 T3 ES2165711 T3 ES 2165711T3 ES 98963218 T ES98963218 T ES 98963218T ES 98963218 T ES98963218 T ES 98963218T ES 2165711 T3 ES2165711 T3 ES 2165711T3
- Authority
- ES
- Spain
- Prior art keywords
- groups
- amino
- substituted
- aryl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003086 colorant Substances 0.000 title 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 title 1
- IRYJRGCIQBGHIV-UHFFFAOYSA-N trimethadione Chemical compound CN1C(=O)OC(C)(C)C1=O IRYJRGCIQBGHIV-UHFFFAOYSA-N 0.000 title 1
- 229960004453 trimethadione Drugs 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 8
- -1 hydroxy, amino Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 5
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 4
- 125000001072 heteroaryl group Chemical group 0.000 abstract 4
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Chemical group CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 3
- 125000000524 functional group Chemical group 0.000 abstract 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 150000007942 carboxylates Chemical class 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- LFGREXWGYUGZLY-UHFFFAOYSA-N phosphoryl Chemical group [P]=O LFGREXWGYUGZLY-UHFFFAOYSA-N 0.000 abstract 2
- 229910052711 selenium Inorganic materials 0.000 abstract 2
- 239000011669 selenium Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003837 (C1-C20) alkyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 239000004721 Polyphenylene oxide Substances 0.000 abstract 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical class [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical group 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229920000570 polyether Polymers 0.000 abstract 1
- 150000003140 primary amides Chemical group 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0075—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of an heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
- C09B23/06—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Lasers (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99221297A | 1997-12-17 | 1997-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2165711T3 true ES2165711T3 (es) | 2002-03-16 |
Family
ID=25538049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98963218T Expired - Lifetime ES2165711T3 (es) | 1997-12-17 | 1998-12-16 | Colorantes de trimetina cianina rigidificada. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6686145B1 (https=) |
| EP (1) | EP1042407B1 (https=) |
| JP (1) | JP4927253B2 (https=) |
| AT (1) | ATE205515T1 (https=) |
| AU (1) | AU760598B2 (https=) |
| CA (1) | CA2314188C (https=) |
| DE (1) | DE69801682T2 (https=) |
| DK (1) | DK1042407T3 (https=) |
| ES (1) | ES2165711T3 (https=) |
| WO (1) | WO1999031181A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133445A (en) * | 1997-12-17 | 2000-10-17 | Carnegie Mellon University | Rigidized trimethine cyanine dyes |
| WO2004039894A2 (en) * | 2002-05-10 | 2004-05-13 | Carnegie Mellon University | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups |
| EP1196398A4 (en) * | 1999-07-06 | 2002-11-06 | Surromed Inc | BRIDGED FLUORESCENT DYES, THEIR PRODUCTION AND USE IN DETECTION METHODS |
| DE19937024A1 (de) * | 1999-08-05 | 2001-02-08 | Bayer Ag | Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker |
| EP1223197B1 (en) | 2001-01-03 | 2012-08-08 | Visen Medical, Inc. | Symmetric, monofunctionalised polymethine dyes labelling reagents |
| EP1221465A1 (en) | 2001-01-03 | 2002-07-10 | Innosense S.r.l. | Symmetric, monofunctionalised polymethine dyes labelling reagents |
| EP1781675B1 (en) | 2004-08-13 | 2014-03-26 | Epoch Biosciences, Inc. | Phosphonate fluorescent dyes and conjugates |
| US7419511B2 (en) * | 2004-09-13 | 2008-09-02 | L'oreal, S.A. | Compositions comprising at least one substituted carbocyanin derivative, processes for treating keratin fibers using them, device therefor and uses thereof |
| US7427301B2 (en) | 2004-09-13 | 2008-09-23 | L'ORéAL S.A. | Composition comprising at least one substituted carbocyanin derivative, process for treating keratin fibers using it, device therefor and use thereof |
| US7425221B2 (en) | 2004-09-13 | 2008-09-16 | L'oreal S.A. | Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use |
| FR2875131B1 (fr) * | 2004-09-13 | 2007-09-28 | Oreal | Composition comprenant au moins un derive substitue de carbocyanine, procede de traitement des fibres keratiniques la mettant en oeuvre, dispositif et utilisation |
| EP1794237A2 (en) | 2004-09-30 | 2007-06-13 | GE Healthcare UK Limited | Fluorescent nucleotide analogues |
| US7282373B2 (en) | 2004-12-23 | 2007-10-16 | Rutgers, The State University Of New Jersey | Ultra-high specificity fluorescent labeling |
| US7381572B2 (en) | 2004-12-23 | 2008-06-03 | Rutgers, The State University Of New Jersey | Reagents and procedures for multi-label high-specificity labeling |
| EP1846754A4 (en) * | 2005-02-01 | 2008-10-08 | Sigma Aldrich Co | Detection of polyaminoacids via trimethylphenin staining |
| US7737281B2 (en) * | 2005-05-24 | 2010-06-15 | Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. | Purine based fluorescent dyes |
| US7569695B2 (en) * | 2005-05-24 | 2009-08-04 | Enzo Life Sciences, Inc. | Dyes for the detection or quantification of desirable target molecules |
| US8357801B2 (en) | 2005-05-24 | 2013-01-22 | Enzo Life Sciences, Inc. | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits |
| CN101296927A (zh) | 2005-09-02 | 2008-10-29 | Visen医药公司 | 生物相容的含n,n-二取代磺酰胺的荧光染料标记 |
| US7947256B2 (en) | 2005-09-02 | 2011-05-24 | Visen Medical, Inc. | Biocompatible fluorescent imaging agents |
| JP5416970B2 (ja) | 2005-09-02 | 2014-02-12 | ビセン メディカル， インコーポレイテッド | ニコチン酸及びピコリン酸誘導近赤外線蛍光団 |
| US7972789B2 (en) * | 2005-11-28 | 2011-07-05 | Dako Denmark A/S | Dye compounds |
| US9334281B2 (en) * | 2008-09-08 | 2016-05-10 | Enzo Life Sciences, Inc. | Fluorochromes for organelle tracing and multi-color imaging |
| US9250249B2 (en) | 2008-09-08 | 2016-02-02 | Enzo Biochem, Inc. | Autophagy and phospholipidosis pathway assays |
| AU2010219097A1 (en) | 2009-01-13 | 2011-08-04 | Glaxo Group Limited | Pyrimidinecarboxamide derivatives as inhibitors of SYK kinase |
| GB201007203D0 (en) | 2010-04-29 | 2010-06-16 | Glaxo Group Ltd | Novel compounds |
| EP2831587B1 (en) | 2012-03-27 | 2018-05-16 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| KR102502117B1 (ko) * | 2015-07-16 | 2023-02-22 | 에스에프씨 주식회사 | 염료 화합물 |
| EP3655408B1 (en) | 2017-08-24 | 2021-07-14 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Conformational restriction of cyanine fluorophores in far-red and near-ir range |
| KR102777649B1 (ko) * | 2017-11-23 | 2025-03-11 | 에스에프씨 주식회사 | 표지용 염료 및 이를 포함하는 표지용 키트 |
| KR102593166B1 (ko) * | 2017-11-23 | 2023-10-25 | 에스에프씨 주식회사 | 표지용 염료 및 이를 포함하는 표지용 키트 |
| AU2019300169A1 (en) | 2018-07-13 | 2021-01-28 | Quantum-Si Incorporated | Biconjugatable labels and methods of use |
| KR102682109B1 (ko) * | 2022-02-10 | 2024-07-05 | 에스에프씨 주식회사 | 신규한 화합물 및 이의 용도 |
| EP4665402A1 (en) | 2023-02-17 | 2025-12-24 | Danmarks Tekniske Universitet | Copolymer-drug conjugate for treatment of tumours |
| WO2025144711A1 (en) * | 2023-12-29 | 2025-07-03 | Illumina, Inc. | Tricyclic polymethine dyes for nucleic acid sequencing |
| CN119285524B (zh) * | 2024-10-11 | 2026-04-10 | 深圳大学 | 一种荧光染料化合物及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3753721A (en) | 1970-08-13 | 1973-08-21 | Eastman Kodak Co | Photographic materials |
| US3915715A (en) | 1970-08-13 | 1975-10-28 | Eastman Kodak Co | Silver halide photographic materials containing a high weight ratio of gold to sulfur sensitizers and a sensitizing methine dye |
| US3679427A (en) * | 1970-10-30 | 1972-07-25 | Eastman Kodak Co | Rigidized carbocyanine dyes and photographic emulsions |
| US3854956A (en) | 1970-10-30 | 1974-12-17 | Eastman Kodak Co | Dyestuffs and spectral sensitizers for silver halide |
| US3821233A (en) | 1970-10-30 | 1974-06-28 | Eastman Kodak Co | Rigidized carbocyanine dyes containing a pyrida-dipyridinium nucleus |
| US3864644A (en) * | 1971-03-22 | 1975-02-04 | Eastman Kodak Co | Dye lasers including rigidized carbocyanine dyes |
| CA985493A (en) * | 1971-03-22 | 1976-03-16 | Eastman Kodak Company | Dye lasers including rigidized carbocyanine dyes |
| US3904637A (en) | 1972-04-19 | 1975-09-09 | Eastman Kodak Co | 7'a'h,8'a'h-bisbenzothiazolo(3,2-a;-3',2'-a)pyrano (3,2-c;5,6-c'+9 dipyridinium compounds and related derivatives thereof |
| DE69624623T2 (de) | 1995-06-07 | 2003-07-24 | Carnegie Mellon University, Pittsburgh | Versteifte Monomethin-Cyaninfarbstoffe |
| US5658735A (en) | 1995-11-09 | 1997-08-19 | Biometric Imaging, Inc. | Cyclized fluorescent nucleic acid intercalating cyanine dyes and nucleic acid detection methods |
| US6133445A (en) | 1997-12-17 | 2000-10-17 | Carnegie Mellon University | Rigidized trimethine cyanine dyes |
-
1998
- 1998-12-16 ES ES98963218T patent/ES2165711T3/es not_active Expired - Lifetime
- 1998-12-16 EP EP98963218A patent/EP1042407B1/en not_active Expired - Lifetime
- 1998-12-16 DE DE69801682T patent/DE69801682T2/de not_active Expired - Lifetime
- 1998-12-16 AT AT98963218T patent/ATE205515T1/de active
- 1998-12-16 AU AU18288/99A patent/AU760598B2/en not_active Expired
- 1998-12-16 DK DK98963218T patent/DK1042407T3/da active
- 1998-12-16 CA CA002314188A patent/CA2314188C/en not_active Expired - Lifetime
- 1998-12-16 WO PCT/US1998/026665 patent/WO1999031181A1/en not_active Ceased
- 1998-12-16 US US09/581,679 patent/US6686145B1/en not_active Expired - Lifetime
- 1998-12-16 JP JP2000539092A patent/JP4927253B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU1828899A (en) | 1999-07-05 |
| DE69801682D1 (en) | 2001-10-18 |
| JP2002508428A (ja) | 2002-03-19 |
| WO1999031181A1 (en) | 1999-06-24 |
| EP1042407B1 (en) | 2001-09-12 |
| AU760598B2 (en) | 2003-05-15 |
| CA2314188C (en) | 2009-11-17 |
| ATE205515T1 (de) | 2001-09-15 |
| CA2314188A1 (en) | 1999-06-24 |
| DK1042407T3 (da) | 2001-12-27 |
| EP1042407A1 (en) | 2000-10-11 |
| DE69801682T2 (de) | 2002-06-20 |
| JP4927253B2 (ja) | 2012-05-09 |
| US6686145B1 (en) | 2004-02-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2165711T3 (es) | Colorantes de trimetina cianina rigidificada. | |
| ES2104887T3 (es) | Derivados de acridina. | |
| AR016666A1 (es) | Derivados de pirimidinona, un procedimiento para su preparacion y una composicion farmaceutica que los contiene | |
| RU2009106712A (ru) | Замещенный фенилтиотрифторид и другие подобные фторирующие агенты | |
| GT199900119A (es) | Jarabe antihistaminico estabilizado. | |
| ES2062395T3 (es) | Nuevos compuestos de bencimidazol y su uso. | |
| ES2168953A1 (es) | Derivados de oxima y su uso como acidos latentes | |
| CO4700455A1 (es) | Derivados tetraciclicos y proceso para su preparacion | |
| NO905306D0 (no) | Spirocykliske forbindelser som inneholder nitrogen. | |
| AR021596A1 (es) | Compuestos que inhiben la procolageno c-proteinasa. | |
| PE20010161A1 (es) | Proceso para separar olefinas de hidrocarburos saturados | |
| ES2059873T3 (es) | 2-alquinilfenoles sustituidos con actividad antiinflamatoria, un procedimiento para su preparacion y sus composiciones farmaceuticas. | |
| ES2062052T3 (es) | Derivados de cicloalcanos. | |
| EA200200098A1 (ru) | Ароматические сложные эфиры для маркировки или мечения нефтепродуктов | |
| ES2148617T3 (es) | Reactivos perfeccionados para un inmunoensayo de cannabinoides. | |
| CO5190715A1 (es) | 1,2,3,4,5,6-hexahidroazepin [4,5-b] indoles que contienen arilsulfonas en la posicion 9 | |
| ES2140383T3 (es) | Derivados de acido propenoico, procedimiento para su preparacion y su uso como fungicidas. | |
| ES471245A1 (es) | Un procedimiento para la preparacion de una composicion her-bicida a base de derivados de n'-fenil-n-metilurea | |
| ES2143483T3 (es) | Cromoionoforos arilazoicos. | |
| AR028740A1 (es) | Procedimiento para la preparacion de pirazolopirimidinonas | |
| ES2039256T3 (es) | Procedimiento para la obtencion de compuestos triciclicos. | |
| ES2128191T3 (es) | Composiciones para el teñido por oxidacion de fibras queratinicas y procedimiento de teñido que las utiliza. | |
| ES2194303T3 (es) | Derivados de (4-piperidinil)-1h-2-benzopirano utiles como agentes antipsicoticos. | |
| ES2159921T3 (es) | Imidazolinas sustituidas por un nucleo heterociclico, como 2-alfa-antagonistas. | |
| ES2060050T3 (es) | Beta-tioacrilamidas s-sustituidas y su uso como microbicidas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 1042407 Country of ref document: ES |