JP4927253B2 - 硬化トリメチンシアニン色素 - Google Patents

硬化トリメチンシアニン色素 Download PDF

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Publication number
JP4927253B2
JP4927253B2 JP2000539092A JP2000539092A JP4927253B2 JP 4927253 B2 JP4927253 B2 JP 4927253B2 JP 2000539092 A JP2000539092 A JP 2000539092A JP 2000539092 A JP2000539092 A JP 2000539092A JP 4927253 B2 JP4927253 B2 JP 4927253B2
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group
compound
amino
groups
alkyl
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Japanese (ja)
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JP2002508428A5 (https=
JP2002508428A (ja
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アラン・エス・ワゴナー
ラットネイカー・ビー・ムジュムダー
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カーネギー メロン ユニヴァーシティ
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0075—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of an heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/06—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Lasers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
JP2000539092A 1997-12-17 1998-12-16 硬化トリメチンシアニン色素 Expired - Lifetime JP4927253B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99221297A 1997-12-17 1997-12-17
US08/992,212 1997-12-17
PCT/US1998/026665 WO1999031181A1 (en) 1997-12-17 1998-12-16 Rigidized trimethine cyanine dyes

Publications (3)

Publication Number Publication Date
JP2002508428A JP2002508428A (ja) 2002-03-19
JP2002508428A5 JP2002508428A5 (https=) 2012-02-02
JP4927253B2 true JP4927253B2 (ja) 2012-05-09

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ID=25538049

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000539092A Expired - Lifetime JP4927253B2 (ja) 1997-12-17 1998-12-16 硬化トリメチンシアニン色素

Country Status (10)

Country Link
US (1) US6686145B1 (https=)
EP (1) EP1042407B1 (https=)
JP (1) JP4927253B2 (https=)
AT (1) ATE205515T1 (https=)
AU (1) AU760598B2 (https=)
CA (1) CA2314188C (https=)
DE (1) DE69801682T2 (https=)
DK (1) DK1042407T3 (https=)
ES (1) ES2165711T3 (https=)
WO (1) WO1999031181A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102777649B1 (ko) * 2017-11-23 2025-03-11 에스에프씨 주식회사 표지용 염료 및 이를 포함하는 표지용 키트

Families Citing this family (35)

* Cited by examiner, † Cited by third party
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US6133445A (en) * 1997-12-17 2000-10-17 Carnegie Mellon University Rigidized trimethine cyanine dyes
WO2004039894A2 (en) * 2002-05-10 2004-05-13 Carnegie Mellon University Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups
US6403807B1 (en) * 1999-07-06 2002-06-11 Surromed, Inc. Bridged fluorescent dyes, their preparation and their use in assays
DE19937024A1 (de) * 1999-08-05 2001-02-08 Bayer Ag Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker
EP1223197B1 (en) 2001-01-03 2012-08-08 Visen Medical, Inc. Symmetric, monofunctionalised polymethine dyes labelling reagents
EP1221465A1 (en) 2001-01-03 2002-07-10 Innosense S.r.l. Symmetric, monofunctionalised polymethine dyes labelling reagents
JP5214967B2 (ja) 2004-08-13 2013-06-19 エポック バイオサイエンシズ インコーポレーティッド ホスホン酸蛍光色素および複合体
US7425221B2 (en) 2004-09-13 2008-09-16 L'oreal S.A. Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use
FR2875131B1 (fr) * 2004-09-13 2007-09-28 Oreal Composition comprenant au moins un derive substitue de carbocyanine, procede de traitement des fibres keratiniques la mettant en oeuvre, dispositif et utilisation
US7427301B2 (en) 2004-09-13 2008-09-23 L'ORéAL S.A. Composition comprising at least one substituted carbocyanin derivative, process for treating keratin fibers using it, device therefor and use thereof
US7419511B2 (en) 2004-09-13 2008-09-02 L'oreal, S.A. Compositions comprising at least one substituted carbocyanin derivative, processes for treating keratin fibers using them, device therefor and uses thereof
EP1794237A2 (en) 2004-09-30 2007-06-13 GE Healthcare UK Limited Fluorescent nucleotide analogues
US7381572B2 (en) 2004-12-23 2008-06-03 Rutgers, The State University Of New Jersey Reagents and procedures for multi-label high-specificity labeling
US7282373B2 (en) 2004-12-23 2007-10-16 Rutgers, The State University Of New Jersey Ultra-high specificity fluorescent labeling
US20060207881A1 (en) * 2005-02-01 2006-09-21 Sigma-Aldrich Co. Detection of polyamino acids using trimethincyanine dyes
US8357801B2 (en) 2005-05-24 2013-01-22 Enzo Life Sciences, Inc. Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits
US7737281B2 (en) * 2005-05-24 2010-06-15 Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. Purine based fluorescent dyes
US7569695B2 (en) * 2005-05-24 2009-08-04 Enzo Life Sciences, Inc. Dyes for the detection or quantification of desirable target molecules
CA2621137C (en) 2005-09-02 2014-07-29 Visen Medical, Inc. Biocompatible n,n-disubstituted sulfonamide-containing fluorescent dye labels
US7947256B2 (en) 2005-09-02 2011-05-24 Visen Medical, Inc. Biocompatible fluorescent imaging agents
EP1934202B1 (en) 2005-09-02 2019-01-09 Visen Medical, Inc. Nicotinic acid and picolinic acid derived near-infrared fluorophores
EP1954763B1 (en) * 2005-11-28 2016-11-16 Dako Denmark A/S Cyanine dyes and methods for detecting a target using said dyes
US9250249B2 (en) 2008-09-08 2016-02-02 Enzo Biochem, Inc. Autophagy and phospholipidosis pathway assays
US9334281B2 (en) * 2008-09-08 2016-05-10 Enzo Life Sciences, Inc. Fluorochromes for organelle tracing and multi-color imaging
US8470835B2 (en) 2009-01-13 2013-06-25 Glaxo Group Limited Pyrimidinecarboxamide derivatives as inhibitors of Syk kinase
GB201007203D0 (en) 2010-04-29 2010-06-16 Glaxo Group Ltd Novel compounds
ES2678211T3 (es) 2012-03-27 2018-08-09 Ventana Medical Systems, Inc. Conjugados de señalización y procedimientos de uso
KR102502117B1 (ko) * 2015-07-16 2023-02-22 에스에프씨 주식회사 염료 화합물
JP7418323B2 (ja) * 2017-08-24 2024-01-19 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 遠赤および近ｉｒ範囲におけるシアニンフルオロフォアの配座の束縛
KR102593166B1 (ko) * 2017-11-23 2023-10-25 에스에프씨 주식회사 표지용 염료 및 이를 포함하는 표지용 키트
CA3105715A1 (en) * 2018-07-13 2020-01-16 Quantum-Si Incorporated Biconjugatable labels and methods of use
WO2023153739A1 (ko) * 2022-02-10 2023-08-17 에스에프씨 주식회사 신규한 화합물 및 이의 용도
JP2026505989A (ja) 2023-02-17 2026-02-20 デンマークス テクニスケ ユニバーシテト 腫瘍の治療のためのコポリマー薬物複合体
US20250215494A1 (en) * 2023-12-29 2025-07-03 Illumina, Inc. Tricyclic polymethine dyes for nucleic acid sequencing
CN119285524B (zh) * 2024-10-11 2026-04-10 深圳大学 一种荧光染料化合物及其制备方法和应用

Citations (2)

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US3679427A (en) * 1970-10-30 1972-07-25 Eastman Kodak Co Rigidized carbocyanine dyes and photographic emulsions
US3864644A (en) * 1971-03-22 1975-02-04 Eastman Kodak Co Dye lasers including rigidized carbocyanine dyes

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US3915715A (en) 1970-08-13 1975-10-28 Eastman Kodak Co Silver halide photographic materials containing a high weight ratio of gold to sulfur sensitizers and a sensitizing methine dye
US3753721A (en) 1970-08-13 1973-08-21 Eastman Kodak Co Photographic materials
US3821233A (en) 1970-10-30 1974-06-28 Eastman Kodak Co Rigidized carbocyanine dyes containing a pyrida-dipyridinium nucleus
US3854956A (en) 1970-10-30 1974-12-17 Eastman Kodak Co Dyestuffs and spectral sensitizers for silver halide
CA985493A (en) 1971-03-22 1976-03-16 Eastman Kodak Company Dye lasers including rigidized carbocyanine dyes
US3904637A (en) 1972-04-19 1975-09-09 Eastman Kodak Co 7'a'h,8'a'h-bisbenzothiazolo(3,2-a;-3',2'-a)pyrano (3,2-c;5,6-c'+9 dipyridinium compounds and related derivatives thereof
EP0747448B1 (en) 1995-06-07 2002-11-06 Carnegie-Mellon University Rigidized monomethine cyanine dyes
US5658735A (en) 1995-11-09 1997-08-19 Biometric Imaging, Inc. Cyclized fluorescent nucleic acid intercalating cyanine dyes and nucleic acid detection methods
US6133445A (en) 1997-12-17 2000-10-17 Carnegie Mellon University Rigidized trimethine cyanine dyes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679427A (en) * 1970-10-30 1972-07-25 Eastman Kodak Co Rigidized carbocyanine dyes and photographic emulsions
US3864644A (en) * 1971-03-22 1975-02-04 Eastman Kodak Co Dye lasers including rigidized carbocyanine dyes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102777649B1 (ko) * 2017-11-23 2025-03-11 에스에프씨 주식회사 표지용 염료 및 이를 포함하는 표지용 키트

Also Published As

Publication number Publication date
DK1042407T3 (da) 2001-12-27
DE69801682D1 (en) 2001-10-18
CA2314188C (en) 2009-11-17
ATE205515T1 (de) 2001-09-15
ES2165711T3 (es) 2002-03-16
EP1042407B1 (en) 2001-09-12
AU760598B2 (en) 2003-05-15
JP2002508428A (ja) 2002-03-19
AU1828899A (en) 1999-07-05
EP1042407A1 (en) 2000-10-11
CA2314188A1 (en) 1999-06-24
US6686145B1 (en) 2004-02-03
DE69801682T2 (de) 2002-06-20
WO1999031181A1 (en) 1999-06-24

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