ES2164757T3 - Supositorio vaginal virucida, bactericida y espermicida. - Google Patents

Supositorio vaginal virucida, bactericida y espermicida.

Info

Publication number
ES2164757T3
ES2164757T3 ES95904215T ES95904215T ES2164757T3 ES 2164757 T3 ES2164757 T3 ES 2164757T3 ES 95904215 T ES95904215 T ES 95904215T ES 95904215 T ES95904215 T ES 95904215T ES 2164757 T3 ES2164757 T3 ES 2164757T3
Authority
ES
Spain
Prior art keywords
lactobacilli
vaginal
suppository
bacteria
micro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95904215T
Other languages
English (en)
Inventor
Larry C Ford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOFEM Inc
Original Assignee
BIOFEM Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/301,966 external-priority patent/US5466463A/en
Application filed by BIOFEM Inc filed Critical BIOFEM Inc
Application granted granted Critical
Publication of ES2164757T3 publication Critical patent/ES2164757T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/15—Suppositories
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y10S435/854—Lactobacillus acidophilus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

UN SUPOSITORIO VAGINAL U OTRO TIPO DE PASADOR VAGINAL COMO CREMA, ESPUMA O POMADA, QUE CONTIENE COMO SUS INGREDIENTES ACTIVOS AL MENOS UN AGENTE ANTIMICROBIANO TOPICAMENTE SEGURO, FARMACEUTICAMENTE ACEPTABLE, COMO UN AGENTE SELECCIONADO DEL GRUPO DE CLORURO DE BENZALCONIO, CLORURO DE CETILPIRIDINIO, GLUCONATO DE CLORHEXIDINA Y YODURO DE POVIDONA, UREA DE IMIDAZOLIDINILO Y UREA DE DIAZOLIDINILO Y UNA COLONIA VIABLE DE BACTERIAS LACTOBACILLI MICRO-ENCAPSULADAS. LOS LACTOBACILLI VIABLES SE INCLUYEN EN EL SUPOSITORIO EN FORMA MICRO ENCAPSULADA, LO CUAL PROTEGE A LA BACTERIA DURANTE EL ALMACENAMIENTO DEL SUPOSITORIO DE LA ACCION DEL AGENTE BACTERICIDA. CUANDO SE EXPONE AL MEDIO VAGINAL LA MICRO ENCAPSULACION SE ROMPE LO SUFICIENTE COMO PARA LIBERAR LAS BACTERIAS LACTOBACILLI. LAS BACTERIAS LACTOBACILLI SIRVEN PARA MANTENER O RESTABLECER UNA FLORA CON BASE DE LACTOBACILLI SALUDABLE EN LA PARED VAGINAL, Y EXCRETAR PEROXIDO DE HIDROGENO Y OTRAS BACTERICIDINAS QUE SUPRIMEN CONDICIONES DE FLORA ANORMAL QUE PROMUEVEN INFECCIONES.
ES95904215T 1993-12-03 1994-12-02 Supositorio vaginal virucida, bactericida y espermicida. Expired - Lifetime ES2164757T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16165993A 1993-12-03 1993-12-03
US08/301,966 US5466463A (en) 1993-12-03 1994-09-07 Viracidal, bactericidal and spermicidal vaginal suppository
PCT/US1994/013882 WO1995015157A1 (en) 1993-12-03 1994-12-02 Viracidal, bactericidal and spermicidal vaginal suppository

Publications (1)

Publication Number Publication Date
ES2164757T3 true ES2164757T3 (es) 2002-03-01

Family

ID=22582168

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95904215T Expired - Lifetime ES2164757T3 (es) 1993-12-03 1994-12-02 Supositorio vaginal virucida, bactericida y espermicida.

Country Status (17)

Country Link
EP (1) EP0732916B1 (es)
JP (1) JPH09506099A (es)
CN (1) CN1084612C (es)
AT (1) ATE205388T1 (es)
AU (1) AU679310B2 (es)
BR (1) BR9408238A (es)
CA (1) CA2176474C (es)
CZ (1) CZ286831B6 (es)
DE (1) DE69428289T2 (es)
ES (1) ES2164757T3 (es)
HU (1) HU219814B (es)
NZ (1) NZ277681A (es)
OA (1) OA10457A (es)
PL (1) PL177505B1 (es)
RU (1) RU2147431C1 (es)
WO (1) WO1995015157A1 (es)
ZA (1) ZA942302B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733568A (en) * 1993-12-03 1998-03-31 Lafor Laboratories Limited Micro-encapsulated lactobacilli for medical applications
US6093394A (en) * 1997-04-11 2000-07-25 Gynelogix, Inc. Vaginal lactobacillus medicant
DK0956858T3 (da) * 1998-04-30 2002-01-28 Vesely Renata Maria Cavaliere Farmaceutiske præparater indeholdende lactobacilli til behandling af vaginale infektioner
EP1082964A1 (en) * 1998-06-05 2001-03-14 Wakamoto Pharmaceutical Co., Ltd. Lactic acid bacterium-containing compositions, drugs and foods
US20030229335A1 (en) * 2002-04-30 2003-12-11 Payne Richard Grady Apparatus and method for delivery of constrained beneficial bacteria to the vaginal tract
CN100421635C (zh) * 2003-01-09 2008-10-01 宏亿生技股份有限公司 涂覆含乳酸菌组成物的保险套
JP2004345999A (ja) * 2003-05-21 2004-12-09 Taiko Pharmaceutical Co Ltd 菌体製剤組成物
US20100310475A1 (en) * 2007-06-18 2010-12-09 Dolhay Klinika Egeszsegugyi Kft. Biocide Capsules, Preparation Comprising them and Sanitary Pad Comprising the Preparation
FR2992861B1 (fr) 2012-07-09 2014-10-17 Probionov Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles
RU2570622C2 (ru) * 2013-10-24 2015-12-10 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" ШТАММ Lactobacillus rhamnosus, ОБЛАДАЮЩИЙ АНТИБАКТЕРИАЛЬНОЙ И АНТИГРИБКОВОЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ПАТОГЕННОЙ И УСЛОВНО-ПАТОГЕННОЙ ВАГИНАЛЬНОЙ МИКРОФЛОРЫ
CN103720640B (zh) * 2013-12-31 2016-01-13 哈尔滨欧替药业有限公司 聚维酮碘阴道膨胀栓及其制备方法和检测方法
CN116869621B (zh) * 2023-09-06 2023-11-10 山东百多安医疗器械股份有限公司 一种带分段涂层痔疮套扎器

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761193B (en) * 1975-03-19 1977-02-23 Procter & Gamble Controlled release articles
CH637297A5 (fr) * 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
DK242083D0 (da) * 1983-05-27 1983-05-27 Hansens Chr Bio Syst Vaginalkapsler
NL8600250A (nl) * 1986-02-01 1987-09-01 Fundatech Sa Vaginaal anticonceptiemiddel.
JPS63104924A (ja) * 1986-10-20 1988-05-10 Kanebo Ltd 膣坐剤
IT1227154B (it) * 1988-08-05 1991-03-19 A Tosi Farmaceutici S R L Nova Composizioni farmaceutiche per uso ginecologico a base di lattobacilli
GB2261372A (en) * 1991-11-15 1993-05-19 Gregor Reid Lactobacillus and skim milk compositions for prevention of urogenital infection
RU2102977C1 (ru) * 1996-09-30 1998-01-27 Открытое акционерное общество "Нижегородский химико-фармацевтический завод" Суппозитории ректальные и вагинальные, обладающие антимикробным, антивирусным и противовоспалительным действием, и способ их получения

Also Published As

Publication number Publication date
ATE205388T1 (de) 2001-09-15
AU1299695A (en) 1995-06-19
CA2176474C (en) 2001-08-21
AU679310B2 (en) 1997-06-26
CN1084612C (zh) 2002-05-15
DE69428289T2 (de) 2002-06-27
NZ277681A (en) 1997-03-24
CZ286831B6 (en) 2000-07-12
CZ160296A3 (en) 1996-09-11
EP0732916B1 (en) 2001-09-12
DE69428289D1 (de) 2001-10-18
OA10457A (en) 2002-03-27
ZA942302B (en) 1995-09-29
EP0732916A4 (en) 1997-09-17
HU9601507D0 (en) 1996-07-29
CA2176474A1 (en) 1995-06-08
PL177505B1 (pl) 1999-11-30
RU2147431C1 (ru) 2000-04-20
WO1995015157A1 (en) 1995-06-08
PL314804A1 (en) 1996-09-30
JPH09506099A (ja) 1997-06-17
EP0732916A1 (en) 1996-09-25
HUT74968A (en) 1997-03-28
BR9408238A (pt) 1997-08-26
HU219814B (hu) 2001-08-28
CN1126071A (zh) 1996-07-10

Similar Documents

Publication Publication Date Title
ES2164757T3 (es) Supositorio vaginal virucida, bactericida y espermicida.
US5227161A (en) Method to clean and disinfect pathogens on the epidermis by applying a composition containing peroxidase, iodide compound and surfactant
AR024874A1 (es) Composiciones bactericidas
US5370815A (en) Viscous epidermal cleaner and disinfectant
TW325405B (en) Pharmaceutical composition as a vaginal passary or suppository comprising antimicrobial agent and micro encapsulated bacteria
US5616347A (en) Chlorine dioxide skin medicating compositions for preventing irritation
CO4440476A1 (es) Composicion sinergistica que comprende una combinacion plaguicida de ingredientes activos .
PE20030096A1 (es) Concentrados en suspension de base oleaginosa
CA2260832A1 (en) Use of a combination of surfactants, chelating agents and essential oils for effective disinfection
EP1100454A4 (en) PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING SKIN STATE
AR012241A1 (es) Composicion de depuracion antimicrobiana mantenible y metodos para proporcionar efectividad residual y para tratar acne.
PL200322B1 (pl) Kompozycja dezynfekująca
ATE401065T1 (de) Orale zubereitungen, die wirtsantwortmodulierenden wirkstoffe enthalten
TW430560B (en) Detergent composition
WO1996018300A3 (en) Adherent disinfecting compositions and methods relating thereto
EP0175338A3 (en) Disinfectants and antiseptics
AR037047A1 (es) Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales
DE60013889D1 (de) Waschmittelzusammensetzungen
EP0737421A4 (en) BACTERICIDE COMPOSITION
Lau et al. Prophylaxis of post-appendicectomy sepsis by metronidazole and ampicillin: a randomized, prospective and double-blind trial
FI97855B (fi) Ei-kontaminoiva antimikrobinen ainekoostumus
BR9811706A (pt) Composições antimicrobianas brandas sem-remoção
UY24638A1 (es) Composición plaguicida de carbaryl y fipronil
TH18740EX (th) ยาเหน็บช่องคลอดที่ฆ่าไวรัสแบคทีเรียและสเปอร์ม
AR027550A1 (es) Una composicion fungicida y el metodo para controlar el crecimiento de hongos con dicha composicion

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 732916

Country of ref document: ES