ES2160834T3 - Derivado de fenil pirimidina opticamente activo como agente analgesico. - Google Patents
Derivado de fenil pirimidina opticamente activo como agente analgesico.Info
- Publication number
- ES2160834T3 ES2160834T3 ES96931006T ES96931006T ES2160834T3 ES 2160834 T3 ES2160834 T3 ES 2160834T3 ES 96931006 T ES96931006 T ES 96931006T ES 96931006 T ES96931006 T ES 96931006T ES 2160834 T3 ES2160834 T3 ES 2160834T3
- Authority
- ES
- Spain
- Prior art keywords
- pirimidine
- phenyl
- derivative
- optically active
- analgesic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Abstract
UNA PIRIMIDINA DE FORMULA (I) Y LAS SALES DE ADICION ACIDAS FARMACEUTICAMENTE ACEPTABLES DE LA MISMA SON UTILES COMO ANALGESICOS, ANTICONVULSIONANTES, O EN EL TRATAMIENTO DEL SINDROME DE INTESTINO IRRITABLE O TRASTORNO BIPOLAR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9518027.9A GB9518027D0 (en) | 1995-09-05 | 1995-09-05 | Pharmacologically active compound |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2160834T3 true ES2160834T3 (es) | 2001-11-16 |
Family
ID=10780172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96931006T Expired - Lifetime ES2160834T3 (es) | 1995-09-05 | 1996-09-03 | Derivado de fenil pirimidina opticamente activo como agente analgesico. |
Country Status (32)
Country | Link |
---|---|
US (1) | US6124308A (es) |
EP (1) | EP0879230B1 (es) |
JP (1) | JPH11512108A (es) |
KR (1) | KR19990044397A (es) |
CN (1) | CN1200729A (es) |
AP (1) | AP640A (es) |
AR (1) | AR004192A1 (es) |
AT (1) | ATE203523T1 (es) |
AU (1) | AU710091B2 (es) |
BG (1) | BG65102B1 (es) |
BR (1) | BR9610388A (es) |
CA (1) | CA2230362A1 (es) |
CO (1) | CO4750651A1 (es) |
CZ (1) | CZ65598A3 (es) |
DE (1) | DE69614150T2 (es) |
EA (1) | EA000695B1 (es) |
ES (1) | ES2160834T3 (es) |
GB (1) | GB9518027D0 (es) |
HR (1) | HRP960399A2 (es) |
HU (1) | HUP9901260A3 (es) |
ID (1) | ID17274A (es) |
IL (1) | IL123414A0 (es) |
IS (1) | IS4673A (es) |
NO (1) | NO980923L (es) |
NZ (1) | NZ318390A (es) |
PL (1) | PL325329A1 (es) |
SK (1) | SK28598A3 (es) |
TR (1) | TR199800386T1 (es) |
TW (1) | TW367326B (es) |
WO (1) | WO1997009317A2 (es) |
YU (1) | YU49796A (es) |
ZA (1) | ZA967466B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR016212A1 (es) * | 1998-04-28 | 2001-06-20 | Astra Ab | Uso de compuestos farmaceuticos que tienen una actividad antagonista de nmda para preparar un medicamento para el tratamiento del sindrome de intestino irritable (ibs), y composiciones farmaceuticas |
US6420354B1 (en) | 1998-06-08 | 2002-07-16 | Advanced Medicine, Inc. | Sodium channel drugs and uses |
AU4550699A (en) * | 1998-06-08 | 1999-12-30 | Advanced Medicine, Inc. | Multibinding agents that modulate the 5-ht transporter |
GB9907965D0 (en) * | 1999-04-09 | 1999-06-02 | Glaxo Group Ltd | Medical use |
US6479498B1 (en) | 1999-06-04 | 2002-11-12 | Theravance, Inc. | Sodium channel drugs and uses |
CA2416819C (en) * | 2000-07-21 | 2011-03-22 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
EP1390355A4 (en) | 2001-02-27 | 2005-02-23 | Teva Pharma | NEW CRYSTALLINE FORMS OF LAMOTRIGIN AND METHOD FOR THE PRODUCTION THEREOF |
EP2266590A3 (en) | 2002-02-22 | 2011-04-20 | Shire LLC | Active agent delivery sytems and methods for protecting and administering active agents |
US20050238724A1 (en) * | 2002-04-23 | 2005-10-27 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing lamotrigine particles of defined morphology |
CA2514574A1 (en) * | 2003-01-30 | 2004-08-12 | Dynogen Pharmaceuticals, Inc. | Use of sodium channel modulators for treating gastrointestinal tract disorders |
GB0603087D0 (en) * | 2006-02-15 | 2006-03-29 | Glaxo Group Ltd | Novel use |
EP2129381A1 (en) | 2007-01-24 | 2009-12-09 | Glaxo Group Limited | Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1 |
GB201111712D0 (en) | 2011-07-08 | 2011-08-24 | Gosforth Ct Holdings Pty Ltd | Pharmaceutical compositions |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK153787C (da) * | 1979-06-01 | 1989-01-16 | Wellcome Found | Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved |
FI895821A0 (fi) * | 1988-12-07 | 1989-12-05 | Wellcome Found | Farmaceutiskt aktiva cns foereningar. |
-
1995
- 1995-09-05 GB GBGB9518027.9A patent/GB9518027D0/en active Pending
-
1996
- 1996-09-03 PL PL96325329A patent/PL325329A1/xx unknown
- 1996-09-03 NZ NZ318390A patent/NZ318390A/xx unknown
- 1996-09-03 CN CN96197823A patent/CN1200729A/zh active Pending
- 1996-09-03 DE DE69614150T patent/DE69614150T2/de not_active Expired - Lifetime
- 1996-09-03 US US09/029,162 patent/US6124308A/en not_active Expired - Fee Related
- 1996-09-03 AU AU69865/96A patent/AU710091B2/en not_active Ceased
- 1996-09-03 HU HU9901260A patent/HUP9901260A3/hu unknown
- 1996-09-03 EP EP96931006A patent/EP0879230B1/en not_active Expired - Lifetime
- 1996-09-03 TR TR1998/00386T patent/TR199800386T1/xx unknown
- 1996-09-03 EA EA199800189A patent/EA000695B1/ru not_active IP Right Cessation
- 1996-09-03 WO PCT/EP1996/003856 patent/WO1997009317A2/en not_active Application Discontinuation
- 1996-09-03 JP JP9510854A patent/JPH11512108A/ja not_active Ceased
- 1996-09-03 ID IDP962513A patent/ID17274A/id unknown
- 1996-09-03 IL IL12341496A patent/IL123414A0/xx unknown
- 1996-09-03 SK SK285-98A patent/SK28598A3/sk unknown
- 1996-09-03 CZ CZ98655A patent/CZ65598A3/cs unknown
- 1996-09-03 ES ES96931006T patent/ES2160834T3/es not_active Expired - Lifetime
- 1996-09-03 KR KR1019980701641A patent/KR19990044397A/ko not_active Application Discontinuation
- 1996-09-03 CA CA002230362A patent/CA2230362A1/en not_active Abandoned
- 1996-09-03 AT AT96931006T patent/ATE203523T1/de not_active IP Right Cessation
- 1996-09-03 BR BR9610388A patent/BR9610388A/pt not_active Application Discontinuation
- 1996-09-03 HR HR9518027.9A patent/HRP960399A2/hr not_active Application Discontinuation
- 1996-09-03 CO CO96046885A patent/CO4750651A1/es unknown
- 1996-09-04 YU YU49796A patent/YU49796A/sh unknown
- 1996-09-04 ZA ZA9607466A patent/ZA967466B/xx unknown
- 1996-09-04 AR ARP960104220A patent/AR004192A1/es unknown
- 1996-09-05 TW TW085110879A patent/TW367326B/zh active
- 1996-09-06 AP APAP/P/1996/000857A patent/AP640A/en active
-
1998
- 1998-02-23 IS IS4673A patent/IS4673A/is unknown
- 1998-03-04 NO NO980923A patent/NO980923L/no not_active Application Discontinuation
- 1998-03-23 BG BG102342A patent/BG65102B1/bg unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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