ES2157566T3 - Proceso para fabricar un chicle medicinal de sabor agradable que contenga un complejo de inclusion. - Google Patents

Proceso para fabricar un chicle medicinal de sabor agradable que contenga un complejo de inclusion.

Info

Publication number
ES2157566T3
ES2157566T3 ES97916602T ES97916602T ES2157566T3 ES 2157566 T3 ES2157566 T3 ES 2157566T3 ES 97916602 T ES97916602 T ES 97916602T ES 97916602 T ES97916602 T ES 97916602T ES 2157566 T3 ES2157566 T3 ES 2157566T3
Authority
ES
Spain
Prior art keywords
gum
inclusion complex
active agent
chicle
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97916602T
Other languages
English (en)
Inventor
Emilio Testa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Atp Avant Garde Technologies &
Original Assignee
Atp Avant Garde Technologies &
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24594294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2157566(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Atp Avant Garde Technologies & filed Critical Atp Avant Garde Technologies &
Application granted granted Critical
Publication of ES2157566T3 publication Critical patent/ES2157566T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBE UN PROCESO PARA LA PREPARACION DE GOMA DE MASCAR (CHICLE), MEDICADA, QUE TIENE UN SABOR AGRADABLE, INDEPENDIENTE DE LOS AGENTES ACTIVOS INCORPORADOS A LA MISMA. EL PROCESO SUPONE LA FORMACION DE UN COMPLEJO DE INCLUSION A BASE DE CICLODEXTRINA QUE CONTIENE EL AGENTE O AGENTES ACTIVOS QUE ESTAN LIOFILIZADOS Y MEZCLADOS CON UNA BASE GRANULADA DE GOMA, SIN AÑADIR AGUA NI OTROS DISOLVENTES. EL PROCESO SE DESARROLLA A TEMPERATURA Y HUMEDAD CONTROLADAS, Y LOS COMPONENTES MEZCLADOS SE COMPRIMEN EN FRIO PARA PRODUCIR UN PRODUCTO FINAL DE GOMA DE MASCAR.
ES97916602T 1996-05-03 1997-04-28 Proceso para fabricar un chicle medicinal de sabor agradable que contenga un complejo de inclusion. Expired - Lifetime ES2157566T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/646,744 US5866179A (en) 1996-05-03 1996-05-03 Medicated chewing gum and a process for preparation thereof

Publications (1)

Publication Number Publication Date
ES2157566T3 true ES2157566T3 (es) 2001-08-16

Family

ID=24594294

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97916602T Expired - Lifetime ES2157566T3 (es) 1996-05-03 1997-04-28 Proceso para fabricar un chicle medicinal de sabor agradable que contenga un complejo de inclusion.

Country Status (11)

Country Link
US (1) US5866179A (es)
EP (1) EP0909166B1 (es)
JP (1) JP2001506227A (es)
AT (1) ATE200024T1 (es)
CA (1) CA2196150C (es)
DE (1) DE69704426T2 (es)
DK (1) DK0909166T3 (es)
ES (1) ES2157566T3 (es)
GR (1) GR3036117T3 (es)
PT (1) PT909166E (es)
WO (1) WO1997041843A2 (es)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1011251A3 (fr) 1997-07-03 1999-06-01 Ucb Sa Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine.
IT1298732B1 (it) * 1998-03-13 2000-02-02 Recordati Chem Pharm Composizioni farmaceutiche orali assumibili senza liquidi,contenenti complessi di inclusione
WO2000019977A1 (en) * 1998-10-08 2000-04-13 Biovail Technologies Ltd. Composition and method for medicated chewing gum delivery system
US6531114B1 (en) 1999-04-06 2003-03-11 Wm. Wrigley Jr. Company Sildenafil citrate chewing gum formulations and methods of using the same
US6627234B1 (en) 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
US7163705B2 (en) * 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US6586023B1 (en) 1998-12-15 2003-07-01 Wm. Wrigley Jr. Company Process for controlling release of active agents from a chewing gum coating and product thereof
US6773716B2 (en) 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6426090B1 (en) * 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
US6322806B1 (en) 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center
US20020159956A1 (en) * 1999-04-06 2002-10-31 Ream Ronald L. Over-coated chewing gum formulations
US6355265B1 (en) 1999-04-06 2002-03-12 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US7935362B2 (en) * 1999-04-06 2011-05-03 Wm. Wrigley Jr. Company Over-coated product including consumable center and medicament
US20040220151A1 (en) * 1999-06-28 2004-11-04 Minu, L.L.C. Process for treating tissue and suppressing pain
US20040219110A1 (en) * 1999-06-28 2004-11-04 Minu , L.L.C. Process for removing calculus deposits from the teeth and suppressing pain
US6436429B1 (en) 1999-06-28 2002-08-20 Gholam A. Peyman Process and composition for temporarily suppressing pain
US6663849B1 (en) 2000-09-01 2003-12-16 Wm. Wrigley Jr. Company Antacid chewing gum products coated with high viscosity materials
US6541048B2 (en) 1999-09-02 2003-04-01 Wm. Wrigley Jr. Company Coated chewing gum products containing an acid blocker and process of preparing
US6645535B2 (en) 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
US6569472B1 (en) 2000-09-01 2003-05-27 Wm. Wrigley Jr. Company Coated chewing gum products containing antacid and method of making
US9387168B2 (en) 1999-09-20 2016-07-12 Jack Barreca Chewing gum with tomatidine
US6491540B1 (en) * 1999-09-20 2002-12-10 Jack Barreca Center-filled supplement gum
US9253991B2 (en) 1999-09-20 2016-02-09 Jack Barreca Chewing gum with B vitamins
US6905672B2 (en) * 1999-12-08 2005-06-14 The Procter & Gamble Company Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants
US6350480B1 (en) 1999-12-30 2002-02-26 Wm. Wrigley Jr. Company Chewing gum product including a hydrophilic gum base and method of producing
DE10013712A1 (de) * 2000-03-20 2001-09-27 Nutrinova Gmbh Nikotinsalze mit verbessertem Geschmack, Verfahren zu ihrer Herstellung und ihre Verwendung
US6582717B1 (en) * 2000-04-07 2003-06-24 Massachusetts Institute Of Technology Drug delivery composition and device
US6572900B1 (en) 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
US7115288B2 (en) * 2000-06-09 2006-10-03 Wm. Wrigley Jr. Company Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener
US6444241B1 (en) 2000-08-30 2002-09-03 Wm. Wrigley Jr. Company Caffeine coated chewing gum product and process of making
US6579545B2 (en) 2000-12-22 2003-06-17 Wm. Wrigley Jr. Company Coated chewing gum products containing an antigas agent
GB0107954D0 (en) * 2001-03-29 2001-05-23 Nestle Sa Chewing gum-containing tablet
KR20010069587A (ko) * 2001-04-18 2001-07-25 전창호 껌의 조성물
US20030086999A1 (en) * 2001-09-18 2003-05-08 Norman Gary T. Chewing gum formulation and method of making the same
US7208186B2 (en) * 2001-09-18 2007-04-24 Spi Pharma, Inc. Chewing gum formulation and method of making the same
PL212123B1 (pl) * 2002-01-15 2012-08-31 Ucb Farchim Sa Doustna kompozycja farmaceutyczna
US20050175733A1 (en) * 2002-07-02 2005-08-11 Bitten Thorengaard Compressed resin moderated chewing gum
EA008858B1 (ru) * 2002-07-02 2007-08-31 Гумлинк А/С Прессованная жевательная резинка
KR101109155B1 (ko) * 2002-07-02 2012-06-20 굼링크 에이/에스 수지로 부드럽게 만든 압축 츄잉 검
ES2623143T3 (es) * 2002-07-02 2017-07-10 Fertin Pharma A/S Tableta II de goma de mascar comprimida
GB0216413D0 (en) * 2002-07-15 2002-08-21 Nestle Sa Tabletted chewing gum sweet
US8591967B2 (en) * 2002-09-24 2013-11-26 Gumlink A/S Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer
WO2004028267A1 (en) * 2002-09-24 2004-04-08 Gumlink A/S Chewing gum having improved release of chewing gum ingredients
MXPA05002961A (es) 2002-09-24 2005-06-03 Gumlink As Goma de mascar que comprende al menos dos diferentes polimeros biodegradables.
CA2501059C (en) * 2002-09-24 2011-03-01 Gumlink A/S Degradable chewing gum polymer
ES2344764T3 (es) * 2002-09-24 2010-09-06 Gumlink A/S Chicle de humedad baja.
WO2004040994A1 (en) * 2002-11-06 2004-05-21 Firmenich Sa Gum base composition
US8602774B2 (en) 2002-12-04 2013-12-10 Bryan Wasylucha Process of tooth whitening and apparatus therefor
DE10300187B4 (de) * 2003-01-08 2007-03-29 Cognis Ip Management Gmbh Kaugummizusammensetzung mit pflanzlichen Wirkstoffen
JP2006516394A (ja) * 2003-02-04 2006-07-06 ガムリンク エー/エス 圧縮チューインガムタブレット
DE10312173A1 (de) * 2003-03-19 2004-09-30 Ingo Hornung Kaugummi mit beigemengten Mitteln
EP1474995B1 (en) * 2003-05-06 2012-11-14 Gumlink A/S A method for producing chewing gum granules, a gum composition extruder and granulating system, and a chewing gum product
DK1474993T3 (da) * 2003-05-06 2009-01-12 Gumlink As Fremgangsmåde til fremstilling af tyggegummigranuler og kornprimerede tyggegummiprodukter, og et tyggegummigranuleringssystem
JP2007525146A (ja) * 2003-12-30 2007-09-06 ガムリンク エー/エス 生分解性ポリマーを含み且つ分解性を促進させたチューインガム
CA2549673A1 (en) * 2003-12-30 2005-07-14 Gumlink A/S Compressed biodegradable chewing gum
US20060018842A1 (en) * 2004-06-25 2006-01-26 Gary Blumenthal Composition and method for delivery of phytochemicals
ATE418328T1 (de) 2004-07-06 2009-01-15 Gumlink As Komprimierte kaugummitablette
DK200401195A (da) * 2004-08-06 2004-08-06 Gumlink As Layered chewing gum tablet
WO2006099866A1 (en) * 2005-03-22 2006-09-28 Gumlink A/S Method of cleaning a surface attached with at least one chewing gum lump
AU2005330149B2 (en) * 2005-03-31 2011-02-24 Mitsubishi Chemical Corporation Deterioration preventing agent
EP2028951B1 (en) * 2006-06-16 2011-04-27 Gumlink A/S Chewing gum comprising a hydrophobic enzyme formulation
JP4709730B2 (ja) * 2006-11-15 2011-06-22 新田ゼラチン株式会社 チュアブルタブレット
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
WO2009007770A1 (en) * 2007-07-06 2009-01-15 Gumlink A/S Chewing gum granules for compressed chewing gum
EP2162013B1 (en) * 2007-07-06 2016-04-06 Gumlink A/S Compressed chewing gum comprising an encapsulation delivery system comprising natural resin
DK2178521T3 (da) * 2007-07-11 2014-04-28 Fertin Pharma As Stabilt medicinsk tyggegummi omfattende cyclodextrin-inklusionskompleks
DK2229156T3 (en) * 2007-12-20 2017-02-06 Fertin Pharma As CHEW GUM TABLE AND PROCEDURE FOR DOSING PHARMACEUTICAL ACTIVE INGREDIENTS IN SUCH CHEW GUM TABLE
WO2009080021A1 (en) 2007-12-20 2009-07-02 Fertin Pharma A/S Compressed chewing gum tablet
DK2229158T3 (en) * 2007-12-20 2016-12-12 Fertin Pharma As Compressed chewing gum tablet
EP2282645B1 (en) 2008-05-26 2015-04-15 Fertin Pharma A/S Flavor impregnation of a chewing gum core
US8506936B2 (en) * 2008-11-25 2013-08-13 Watson Laboratories, Inc. Stabilized nicotine chewing gum
EP2373179B1 (en) 2008-12-19 2018-08-01 Fertin Pharma A/S Multi-part kit comprising a chewing gum and further a flavor containing formulation
KR101138851B1 (ko) * 2009-04-27 2012-05-09 김만규 금연 껌 조성물 및 그를 이용한 금연 껌 제조방법
WO2010127353A2 (en) * 2009-05-01 2010-11-04 Basf Corporation Chlorine dioxide based gum and candy
US20110038915A1 (en) * 2009-08-14 2011-02-17 Eduardo Jose Gonzalez Chewing Gum Formula for Enhancing Psycho-Spirituality
US20130101527A1 (en) * 2011-10-14 2013-04-25 Rodolfo R. Llinas Methods, compounds and pharmaceutical compositions for treating neurological disorders
US20150313847A1 (en) * 2012-12-07 2015-11-05 Gumlink A/S Compressed Tablets
EP2808319A1 (en) * 2013-05-31 2014-12-03 Arevipharma GmbH 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex
US9744128B2 (en) 2014-06-05 2017-08-29 Mastix LLC Method for manufacturing medicated chewing gum without cooling
US10765658B2 (en) 2016-06-22 2020-09-08 Mastix LLC Oral compositions delivering therapeutically effective amounts of cannabinoids
JP7137850B2 (ja) * 2017-03-03 2022-09-15 シーティーシー バイオ インク バレニクリンまたはその薬学的に許容可能な塩の包接複合体を含む口腔投与用製剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3262784A (en) * 1963-12-02 1966-07-26 Frank H Fleer Corp Chewing gum product and method of making same
US4068004A (en) * 1976-06-30 1978-01-10 Life Savers, Inc. System and method for cooling of gum base
US4161546A (en) * 1977-08-03 1979-07-17 Standard Oil Company (Indiana) Process for texturizing proteinaceous materials
US4348416A (en) * 1980-08-07 1982-09-07 International Flavors & Fragrances Inc. Flavoring with 1-ethoxy-1-ethanol acetate - acetaldehyde mixtures
CA1240875A (en) * 1984-01-31 1988-08-23 Subraman R. Cherukuri Tableted chewing gum composition and method of preparation
JPH0826345B2 (ja) * 1986-07-10 1996-03-13 株式会社林原生物化学研究所 固状油溶性物質の製造方法
US5370881A (en) * 1987-04-20 1994-12-06 Fuisz Technologies Ltd. Water-soluble delivery systems for hydrophobic liquids
JP2545559B2 (ja) * 1987-05-02 1996-10-23 和也 小山 チューインガム成形における離型方法
US5229148A (en) * 1989-04-19 1993-07-20 Wm. Wrigley Jr. Company Method of combining active ingredients with polyvinyl acetates
JPH07583B2 (ja) * 1990-11-21 1995-01-11 北海道糖業株式会社 水溶性五環性トリテルペン包接化合物及びその製造方法並びにそれを利用した食品、飲料、口腔用組成物
US5165943A (en) * 1991-06-21 1992-11-24 Wm. Wrigley Jr. Company Cooling agent/cyclodextrin complex for improved flavor release
NZ243667A (en) * 1991-08-02 1995-02-24 Kurihara Yoshie Chewing gum containing coated curculin derivative or fruit containing curculin
DE4220735A1 (de) * 1992-06-25 1994-01-13 Puetter Medice Chem Pharm Kaugummizubereitungen
WO1995003709A1 (fr) * 1993-07-30 1995-02-09 Firmenich S.A. Procede d'aromatisation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation

Also Published As

Publication number Publication date
CA2196150C (en) 2003-04-15
US5866179A (en) 1999-02-02
ATE200024T1 (de) 2001-04-15
CA2196150A1 (en) 1997-11-04
DK0909166T3 (da) 2001-08-13
DE69704426T2 (de) 2001-11-15
EP0909166B1 (en) 2001-03-28
PT909166E (pt) 2001-09-28
WO1997041843A3 (en) 1997-12-11
JP2001506227A (ja) 2001-05-15
WO1997041843A2 (en) 1997-11-13
GR3036117T3 (en) 2001-09-28
MX9703317A (es) 1998-06-30
EP0909166A2 (en) 1999-04-21
DE69704426D1 (de) 2001-05-03

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