ES2157566T3 - Proceso para fabricar un chicle medicinal de sabor agradable que contenga un complejo de inclusion. - Google Patents
Proceso para fabricar un chicle medicinal de sabor agradable que contenga un complejo de inclusion.Info
- Publication number
- ES2157566T3 ES2157566T3 ES97916602T ES97916602T ES2157566T3 ES 2157566 T3 ES2157566 T3 ES 2157566T3 ES 97916602 T ES97916602 T ES 97916602T ES 97916602 T ES97916602 T ES 97916602T ES 2157566 T3 ES2157566 T3 ES 2157566T3
- Authority
- ES
- Spain
- Prior art keywords
- gum
- inclusion complex
- active agent
- chicle
- manufacturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Confectionery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE DESCRIBE UN PROCESO PARA LA PREPARACION DE GOMA DE MASCAR (CHICLE), MEDICADA, QUE TIENE UN SABOR AGRADABLE, INDEPENDIENTE DE LOS AGENTES ACTIVOS INCORPORADOS A LA MISMA. EL PROCESO SUPONE LA FORMACION DE UN COMPLEJO DE INCLUSION A BASE DE CICLODEXTRINA QUE CONTIENE EL AGENTE O AGENTES ACTIVOS QUE ESTAN LIOFILIZADOS Y MEZCLADOS CON UNA BASE GRANULADA DE GOMA, SIN AÑADIR AGUA NI OTROS DISOLVENTES. EL PROCESO SE DESARROLLA A TEMPERATURA Y HUMEDAD CONTROLADAS, Y LOS COMPONENTES MEZCLADOS SE COMPRIMEN EN FRIO PARA PRODUCIR UN PRODUCTO FINAL DE GOMA DE MASCAR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/646,744 US5866179A (en) | 1996-05-03 | 1996-05-03 | Medicated chewing gum and a process for preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2157566T3 true ES2157566T3 (es) | 2001-08-16 |
Family
ID=24594294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97916602T Expired - Lifetime ES2157566T3 (es) | 1996-05-03 | 1997-04-28 | Proceso para fabricar un chicle medicinal de sabor agradable que contenga un complejo de inclusion. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5866179A (es) |
EP (1) | EP0909166B1 (es) |
JP (1) | JP2001506227A (es) |
AT (1) | ATE200024T1 (es) |
CA (1) | CA2196150C (es) |
DE (1) | DE69704426T2 (es) |
DK (1) | DK0909166T3 (es) |
ES (1) | ES2157566T3 (es) |
GR (1) | GR3036117T3 (es) |
PT (1) | PT909166E (es) |
WO (1) | WO1997041843A2 (es) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE1011251A3 (fr) | 1997-07-03 | 1999-06-01 | Ucb Sa | Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine. |
IT1298732B1 (it) * | 1998-03-13 | 2000-02-02 | Recordati Chem Pharm | Composizioni farmaceutiche orali assumibili senza liquidi,contenenti complessi di inclusione |
WO2000019977A1 (en) * | 1998-10-08 | 2000-04-13 | Biovail Technologies Ltd. | Composition and method for medicated chewing gum delivery system |
US6531114B1 (en) | 1999-04-06 | 2003-03-11 | Wm. Wrigley Jr. Company | Sildenafil citrate chewing gum formulations and methods of using the same |
US6627234B1 (en) | 1998-12-15 | 2003-09-30 | Wm. Wrigley Jr. Company | Method of producing active agent coated chewing gum products |
US7163705B2 (en) * | 1998-12-15 | 2007-01-16 | Wm. Wrigley Jr. Company | Coated chewing gum product and method of making |
US6586023B1 (en) | 1998-12-15 | 2003-07-01 | Wm. Wrigley Jr. Company | Process for controlling release of active agents from a chewing gum coating and product thereof |
US6773716B2 (en) | 1999-04-06 | 2004-08-10 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US6426090B1 (en) * | 1999-04-06 | 2002-07-30 | Wm. Wrigley Jr. Company | Over-coated product including tableted center and medicament |
US6322806B1 (en) | 1999-04-06 | 2001-11-27 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations including tableted center |
US20020159956A1 (en) * | 1999-04-06 | 2002-10-31 | Ream Ronald L. | Over-coated chewing gum formulations |
US6355265B1 (en) | 1999-04-06 | 2002-03-12 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US7935362B2 (en) * | 1999-04-06 | 2011-05-03 | Wm. Wrigley Jr. Company | Over-coated product including consumable center and medicament |
US20040220151A1 (en) * | 1999-06-28 | 2004-11-04 | Minu, L.L.C. | Process for treating tissue and suppressing pain |
US20040219110A1 (en) * | 1999-06-28 | 2004-11-04 | Minu , L.L.C. | Process for removing calculus deposits from the teeth and suppressing pain |
US6436429B1 (en) | 1999-06-28 | 2002-08-20 | Gholam A. Peyman | Process and composition for temporarily suppressing pain |
US6663849B1 (en) | 2000-09-01 | 2003-12-16 | Wm. Wrigley Jr. Company | Antacid chewing gum products coated with high viscosity materials |
US6541048B2 (en) | 1999-09-02 | 2003-04-01 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an acid blocker and process of preparing |
US6645535B2 (en) | 1999-09-02 | 2003-11-11 | Wm. Wrigley Jr. Company | Method of making coated chewing gum products containing various antacids |
US6569472B1 (en) | 2000-09-01 | 2003-05-27 | Wm. Wrigley Jr. Company | Coated chewing gum products containing antacid and method of making |
US9387168B2 (en) | 1999-09-20 | 2016-07-12 | Jack Barreca | Chewing gum with tomatidine |
US6491540B1 (en) * | 1999-09-20 | 2002-12-10 | Jack Barreca | Center-filled supplement gum |
US9253991B2 (en) | 1999-09-20 | 2016-02-09 | Jack Barreca | Chewing gum with B vitamins |
US6905672B2 (en) * | 1999-12-08 | 2005-06-14 | The Procter & Gamble Company | Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants |
US6350480B1 (en) | 1999-12-30 | 2002-02-26 | Wm. Wrigley Jr. Company | Chewing gum product including a hydrophilic gum base and method of producing |
DE10013712A1 (de) * | 2000-03-20 | 2001-09-27 | Nutrinova Gmbh | Nikotinsalze mit verbessertem Geschmack, Verfahren zu ihrer Herstellung und ihre Verwendung |
US6582717B1 (en) * | 2000-04-07 | 2003-06-24 | Massachusetts Institute Of Technology | Drug delivery composition and device |
US6572900B1 (en) | 2000-06-09 | 2003-06-03 | Wm. Wrigley, Jr. Company | Method for making coated chewing gum products including a high-intensity sweetener |
US7115288B2 (en) * | 2000-06-09 | 2006-10-03 | Wm. Wrigley Jr. Company | Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener |
US6444241B1 (en) | 2000-08-30 | 2002-09-03 | Wm. Wrigley Jr. Company | Caffeine coated chewing gum product and process of making |
US6579545B2 (en) | 2000-12-22 | 2003-06-17 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an antigas agent |
GB0107954D0 (en) * | 2001-03-29 | 2001-05-23 | Nestle Sa | Chewing gum-containing tablet |
KR20010069587A (ko) * | 2001-04-18 | 2001-07-25 | 전창호 | 껌의 조성물 |
US20030086999A1 (en) * | 2001-09-18 | 2003-05-08 | Norman Gary T. | Chewing gum formulation and method of making the same |
US7208186B2 (en) * | 2001-09-18 | 2007-04-24 | Spi Pharma, Inc. | Chewing gum formulation and method of making the same |
PL212123B1 (pl) * | 2002-01-15 | 2012-08-31 | Ucb Farchim Sa | Doustna kompozycja farmaceutyczna |
US20050175733A1 (en) * | 2002-07-02 | 2005-08-11 | Bitten Thorengaard | Compressed resin moderated chewing gum |
EA008858B1 (ru) * | 2002-07-02 | 2007-08-31 | Гумлинк А/С | Прессованная жевательная резинка |
KR101109155B1 (ko) * | 2002-07-02 | 2012-06-20 | 굼링크 에이/에스 | 수지로 부드럽게 만든 압축 츄잉 검 |
ES2623143T3 (es) * | 2002-07-02 | 2017-07-10 | Fertin Pharma A/S | Tableta II de goma de mascar comprimida |
GB0216413D0 (en) * | 2002-07-15 | 2002-08-21 | Nestle Sa | Tabletted chewing gum sweet |
US8591967B2 (en) * | 2002-09-24 | 2013-11-26 | Gumlink A/S | Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer |
WO2004028267A1 (en) * | 2002-09-24 | 2004-04-08 | Gumlink A/S | Chewing gum having improved release of chewing gum ingredients |
MXPA05002961A (es) | 2002-09-24 | 2005-06-03 | Gumlink As | Goma de mascar que comprende al menos dos diferentes polimeros biodegradables. |
CA2501059C (en) * | 2002-09-24 | 2011-03-01 | Gumlink A/S | Degradable chewing gum polymer |
ES2344764T3 (es) * | 2002-09-24 | 2010-09-06 | Gumlink A/S | Chicle de humedad baja. |
WO2004040994A1 (en) * | 2002-11-06 | 2004-05-21 | Firmenich Sa | Gum base composition |
US8602774B2 (en) | 2002-12-04 | 2013-12-10 | Bryan Wasylucha | Process of tooth whitening and apparatus therefor |
DE10300187B4 (de) * | 2003-01-08 | 2007-03-29 | Cognis Ip Management Gmbh | Kaugummizusammensetzung mit pflanzlichen Wirkstoffen |
JP2006516394A (ja) * | 2003-02-04 | 2006-07-06 | ガムリンク エー/エス | 圧縮チューインガムタブレット |
DE10312173A1 (de) * | 2003-03-19 | 2004-09-30 | Ingo Hornung | Kaugummi mit beigemengten Mitteln |
EP1474995B1 (en) * | 2003-05-06 | 2012-11-14 | Gumlink A/S | A method for producing chewing gum granules, a gum composition extruder and granulating system, and a chewing gum product |
DK1474993T3 (da) * | 2003-05-06 | 2009-01-12 | Gumlink As | Fremgangsmåde til fremstilling af tyggegummigranuler og kornprimerede tyggegummiprodukter, og et tyggegummigranuleringssystem |
JP2007525146A (ja) * | 2003-12-30 | 2007-09-06 | ガムリンク エー/エス | 生分解性ポリマーを含み且つ分解性を促進させたチューインガム |
CA2549673A1 (en) * | 2003-12-30 | 2005-07-14 | Gumlink A/S | Compressed biodegradable chewing gum |
US20060018842A1 (en) * | 2004-06-25 | 2006-01-26 | Gary Blumenthal | Composition and method for delivery of phytochemicals |
ATE418328T1 (de) | 2004-07-06 | 2009-01-15 | Gumlink As | Komprimierte kaugummitablette |
DK200401195A (da) * | 2004-08-06 | 2004-08-06 | Gumlink As | Layered chewing gum tablet |
WO2006099866A1 (en) * | 2005-03-22 | 2006-09-28 | Gumlink A/S | Method of cleaning a surface attached with at least one chewing gum lump |
AU2005330149B2 (en) * | 2005-03-31 | 2011-02-24 | Mitsubishi Chemical Corporation | Deterioration preventing agent |
EP2028951B1 (en) * | 2006-06-16 | 2011-04-27 | Gumlink A/S | Chewing gum comprising a hydrophobic enzyme formulation |
JP4709730B2 (ja) * | 2006-11-15 | 2011-06-22 | 新田ゼラチン株式会社 | チュアブルタブレット |
US20080286340A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered nicotine containing products |
WO2009007770A1 (en) * | 2007-07-06 | 2009-01-15 | Gumlink A/S | Chewing gum granules for compressed chewing gum |
EP2162013B1 (en) * | 2007-07-06 | 2016-04-06 | Gumlink A/S | Compressed chewing gum comprising an encapsulation delivery system comprising natural resin |
DK2178521T3 (da) * | 2007-07-11 | 2014-04-28 | Fertin Pharma As | Stabilt medicinsk tyggegummi omfattende cyclodextrin-inklusionskompleks |
DK2229156T3 (en) * | 2007-12-20 | 2017-02-06 | Fertin Pharma As | CHEW GUM TABLE AND PROCEDURE FOR DOSING PHARMACEUTICAL ACTIVE INGREDIENTS IN SUCH CHEW GUM TABLE |
WO2009080021A1 (en) | 2007-12-20 | 2009-07-02 | Fertin Pharma A/S | Compressed chewing gum tablet |
DK2229158T3 (en) * | 2007-12-20 | 2016-12-12 | Fertin Pharma As | Compressed chewing gum tablet |
EP2282645B1 (en) | 2008-05-26 | 2015-04-15 | Fertin Pharma A/S | Flavor impregnation of a chewing gum core |
US8506936B2 (en) * | 2008-11-25 | 2013-08-13 | Watson Laboratories, Inc. | Stabilized nicotine chewing gum |
EP2373179B1 (en) | 2008-12-19 | 2018-08-01 | Fertin Pharma A/S | Multi-part kit comprising a chewing gum and further a flavor containing formulation |
KR101138851B1 (ko) * | 2009-04-27 | 2012-05-09 | 김만규 | 금연 껌 조성물 및 그를 이용한 금연 껌 제조방법 |
WO2010127353A2 (en) * | 2009-05-01 | 2010-11-04 | Basf Corporation | Chlorine dioxide based gum and candy |
US20110038915A1 (en) * | 2009-08-14 | 2011-02-17 | Eduardo Jose Gonzalez | Chewing Gum Formula for Enhancing Psycho-Spirituality |
US20130101527A1 (en) * | 2011-10-14 | 2013-04-25 | Rodolfo R. Llinas | Methods, compounds and pharmaceutical compositions for treating neurological disorders |
US20150313847A1 (en) * | 2012-12-07 | 2015-11-05 | Gumlink A/S | Compressed Tablets |
EP2808319A1 (en) * | 2013-05-31 | 2014-12-03 | Arevipharma GmbH | 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex |
US9744128B2 (en) | 2014-06-05 | 2017-08-29 | Mastix LLC | Method for manufacturing medicated chewing gum without cooling |
US10765658B2 (en) | 2016-06-22 | 2020-09-08 | Mastix LLC | Oral compositions delivering therapeutically effective amounts of cannabinoids |
JP7137850B2 (ja) * | 2017-03-03 | 2022-09-15 | シーティーシー バイオ インク | バレニクリンまたはその薬学的に許容可能な塩の包接複合体を含む口腔投与用製剤 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3262784A (en) * | 1963-12-02 | 1966-07-26 | Frank H Fleer Corp | Chewing gum product and method of making same |
US4068004A (en) * | 1976-06-30 | 1978-01-10 | Life Savers, Inc. | System and method for cooling of gum base |
US4161546A (en) * | 1977-08-03 | 1979-07-17 | Standard Oil Company (Indiana) | Process for texturizing proteinaceous materials |
US4348416A (en) * | 1980-08-07 | 1982-09-07 | International Flavors & Fragrances Inc. | Flavoring with 1-ethoxy-1-ethanol acetate - acetaldehyde mixtures |
CA1240875A (en) * | 1984-01-31 | 1988-08-23 | Subraman R. Cherukuri | Tableted chewing gum composition and method of preparation |
JPH0826345B2 (ja) * | 1986-07-10 | 1996-03-13 | 株式会社林原生物化学研究所 | 固状油溶性物質の製造方法 |
US5370881A (en) * | 1987-04-20 | 1994-12-06 | Fuisz Technologies Ltd. | Water-soluble delivery systems for hydrophobic liquids |
JP2545559B2 (ja) * | 1987-05-02 | 1996-10-23 | 和也 小山 | チューインガム成形における離型方法 |
US5229148A (en) * | 1989-04-19 | 1993-07-20 | Wm. Wrigley Jr. Company | Method of combining active ingredients with polyvinyl acetates |
JPH07583B2 (ja) * | 1990-11-21 | 1995-01-11 | 北海道糖業株式会社 | 水溶性五環性トリテルペン包接化合物及びその製造方法並びにそれを利用した食品、飲料、口腔用組成物 |
US5165943A (en) * | 1991-06-21 | 1992-11-24 | Wm. Wrigley Jr. Company | Cooling agent/cyclodextrin complex for improved flavor release |
NZ243667A (en) * | 1991-08-02 | 1995-02-24 | Kurihara Yoshie | Chewing gum containing coated curculin derivative or fruit containing curculin |
DE4220735A1 (de) * | 1992-06-25 | 1994-01-13 | Puetter Medice Chem Pharm | Kaugummizubereitungen |
WO1995003709A1 (fr) * | 1993-07-30 | 1995-02-09 | Firmenich S.A. | Procede d'aromatisation |
US5362496A (en) * | 1993-08-04 | 1994-11-08 | Pharmetrix Corporation | Method and therapeutic system for smoking cessation |
-
1996
- 1996-05-03 US US08/646,744 patent/US5866179A/en not_active Expired - Lifetime
-
1997
- 1997-01-28 CA CA002196150A patent/CA2196150C/en not_active Expired - Fee Related
- 1997-04-28 AT AT97916602T patent/ATE200024T1/de not_active IP Right Cessation
- 1997-04-28 JP JP53967997A patent/JP2001506227A/ja not_active Ceased
- 1997-04-28 PT PT97916602T patent/PT909166E/pt unknown
- 1997-04-28 DE DE69704426T patent/DE69704426T2/de not_active Expired - Fee Related
- 1997-04-28 DK DK97916602T patent/DK0909166T3/da active
- 1997-04-28 ES ES97916602T patent/ES2157566T3/es not_active Expired - Lifetime
- 1997-04-28 EP EP97916602A patent/EP0909166B1/en not_active Revoked
- 1997-04-28 WO PCT/IB1997/000449 patent/WO1997041843A2/en not_active Application Discontinuation
-
2001
- 2001-06-26 GR GR20010400970T patent/GR3036117T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2196150C (en) | 2003-04-15 |
US5866179A (en) | 1999-02-02 |
ATE200024T1 (de) | 2001-04-15 |
CA2196150A1 (en) | 1997-11-04 |
DK0909166T3 (da) | 2001-08-13 |
DE69704426T2 (de) | 2001-11-15 |
EP0909166B1 (en) | 2001-03-28 |
PT909166E (pt) | 2001-09-28 |
WO1997041843A3 (en) | 1997-12-11 |
JP2001506227A (ja) | 2001-05-15 |
WO1997041843A2 (en) | 1997-11-13 |
GR3036117T3 (en) | 2001-09-28 |
MX9703317A (es) | 1998-06-30 |
EP0909166A2 (en) | 1999-04-21 |
DE69704426D1 (de) | 2001-05-03 |
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