HRP20000781B1 - Effervescent preparations - Google Patents

Effervescent preparations

Info

Publication number
HRP20000781B1
HRP20000781B1 HR20000781A HRP20000781A HRP20000781B1 HR P20000781 B1 HRP20000781 B1 HR P20000781B1 HR 20000781 A HR20000781 A HR 20000781A HR P20000781 A HRP20000781 A HR P20000781A HR P20000781 B1 HRP20000781 B1 HR P20000781B1
Authority
HR
Croatia
Prior art keywords
sugar
effervescent
effervescent preparations
components
effervescent composition
Prior art date
Application number
HR20000781A
Other languages
Croatian (hr)
Inventor
Walter Reinhard
Ohage Petra
Original Assignee
Bayer Schering Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Aktiengesellschaft filed Critical Bayer Schering Pharma Aktiengesellschaft
Publication of HRP20000781A2 publication Critical patent/HRP20000781A2/en
Publication of HRP20000781B1 publication Critical patent/HRP20000781B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Abstract

Postupak za proizvodnju lijeka koji sadrži šumeće pripravke izA. šumećeg sastava koji sadrži (i) davatelja CO2 i (ii) kiselu komponentu, B. farmaceutske djelotvorne tvari iC. pomoćne tvari, naznačen time, dase barem jedna od obje komponente A(i), A(ii) i u danom slučaju dodatne komponente šumećeg pripravka dispergiraju u rastaljenom C) šećeru i/ili šećernom alkoholu i/ili šećernom nadomjestku, te se nastala smjesa u danom slučaju tabletira. Patent sadrži još 6 patentnih zahtjeva.A process for the manufacture of a medicament containing effervescent preparations ofA. effervescent composition containing (i) a CO2 donor and (ii) an acidic component, B. a pharmaceutically active substance iC. excipients, characterized in that at least one of the two components A (i), A (ii) and optionally the additional components of the effervescent composition are dispersed in molten C) sugar and / or sugar alcohol and / or sugar substitute, and the resulting mixture in given the tablet. The patent contains 6 more patent claims.

HR20000781A 1998-05-15 2000-11-15 Effervescent preparations HRP20000781B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19822036A DE19822036A1 (en) 1998-05-15 1998-05-15 Effervescent pharmaceutical composition with improved stability
PCT/EP1999/002969 WO1999059553A1 (en) 1998-05-15 1999-05-03 Effervescent preparations

Publications (2)

Publication Number Publication Date
HRP20000781A2 HRP20000781A2 (en) 2001-06-30
HRP20000781B1 true HRP20000781B1 (en) 2010-06-30

Family

ID=7868010

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000781A HRP20000781B1 (en) 1998-05-15 2000-11-15 Effervescent preparations

Country Status (30)

Country Link
EP (1) EP1077684B1 (en)
JP (1) JP4452403B2 (en)
KR (1) KR100629817B1 (en)
AR (1) AR016473A1 (en)
AT (1) ATE246494T1 (en)
AU (1) AU3929799A (en)
BR (1) BR9910454A (en)
CA (1) CA2331671C (en)
CO (1) CO4830457A1 (en)
CZ (1) CZ300778B6 (en)
DE (2) DE19822036A1 (en)
DK (1) DK1077684T3 (en)
EE (1) EE04701B1 (en)
ES (1) ES2203134T3 (en)
GT (1) GT199900062A (en)
HN (1) HN1999000067A (en)
HR (1) HRP20000781B1 (en)
HU (1) HU224034B1 (en)
ID (1) ID27441A (en)
IL (1) IL139240A (en)
NO (1) NO20005722L (en)
PA (1) PA8472001A1 (en)
PE (1) PE20000465A1 (en)
PL (1) PL194347B1 (en)
PT (1) PT1077684E (en)
SI (1) SI1077684T1 (en)
SK (1) SK284621B6 (en)
TR (1) TR200003357T2 (en)
UY (1) UY25510A1 (en)
WO (1) WO1999059553A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649186B1 (en) * 1996-09-20 2003-11-18 Ethypharm Effervescent granules and methods for their preparation
ES2215025T3 (en) * 1999-02-11 2004-10-01 Hexal Ag EFERVESCENT PHARMACEUTICAL FORMULATION, CONTAINING METAMIZOL.
FR2823668B1 (en) * 2001-04-20 2004-02-27 Ethypharm Lab Prod Ethiques ORODISPERSIBLE EFFERVESCENT TABLETS
US8846088B2 (en) 2005-02-03 2014-09-30 Takeda Nycomed As Melt granulation of a composition containing a calcium-containing compound
GR1007299B (en) * 2010-03-24 2011-06-06 Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε, Original effervescent hydrochloric metformin composition in the form of tablets
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
AU2015316552C1 (en) 2014-09-17 2018-08-23 Steerlife India Private Limited Effervescent composition and method of making it
US11559483B2 (en) * 2015-07-10 2023-01-24 Sanjay Gupta Nasal foam via cribriform plate for medication delivery to the brain and/or body and for nasal moisturization and hygiene
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
JP2018183067A (en) * 2017-04-24 2018-11-22 株式会社松原製餡所 Expandable additive and bean jam food product

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3653914A (en) * 1970-03-20 1972-04-04 Alberto Culver Co Production of tablets
US4004036A (en) * 1966-05-31 1977-01-18 Alberto Culver Company Effervescent molded triturate tablets
GB2307857A (en) * 1995-12-04 1997-06-11 Euro Celtique Sa An effervescent tablet containing tramadol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE108649T1 (en) * 1990-02-14 1994-08-15 Takeda Chemical Industries Ltd SHOWER MIX, ITS PRODUCTION AND USE.
RU2096955C1 (en) * 1991-03-01 1997-11-27 Е.И.Дюпон Де Немур Энд Компани Water-dispersable granulated pesticide composition prepared by extrusion method and a method of its preparing
MX9300110A (en) * 1992-01-13 1994-07-29 Gerhard Gergely PHARMACEUTICAL PREPARATION IN THE FORM OF AN EFFERVESCENCE OR DISINTEGRATION TABLET OR OF AN INSTANT-TYPE GRANULATE AND PROCEDURE FOR ITS PREPARATION.
HU217125B (en) * 1993-03-10 1999-11-29 Béres Rt. Sugar- and sodium-free effervescens tablets and granules and process for producing them
WO1995007070A1 (en) * 1993-09-09 1995-03-16 Gerhard Gergely Effervescent granulated material and method for its preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004036A (en) * 1966-05-31 1977-01-18 Alberto Culver Company Effervescent molded triturate tablets
US3653914A (en) * 1970-03-20 1972-04-04 Alberto Culver Co Production of tablets
GB2307857A (en) * 1995-12-04 1997-06-11 Euro Celtique Sa An effervescent tablet containing tramadol

Also Published As

Publication number Publication date
DE59906519D1 (en) 2003-09-11
PE20000465A1 (en) 2000-07-07
HUP0101822A3 (en) 2002-12-28
TR200003357T2 (en) 2001-05-21
HU224034B1 (en) 2005-05-30
CA2331671A1 (en) 1999-11-25
KR20010043600A (en) 2001-05-25
AU3929799A (en) 1999-12-06
PA8472001A1 (en) 2000-09-29
CZ300778B6 (en) 2009-08-12
ES2203134T3 (en) 2004-04-01
SI1077684T1 (en) 2003-12-31
WO1999059553A1 (en) 1999-11-25
SK17062000A3 (en) 2001-04-09
CZ20004171A3 (en) 2001-03-14
PL344140A1 (en) 2001-10-08
SK284621B6 (en) 2005-07-01
JP2002515422A (en) 2002-05-28
HRP20000781A2 (en) 2001-06-30
EE04701B1 (en) 2006-10-16
DK1077684T3 (en) 2003-11-17
IL139240A (en) 2005-08-31
GT199900062A (en) 2000-10-20
AR016473A1 (en) 2001-07-04
ATE246494T1 (en) 2003-08-15
CA2331671C (en) 2008-01-08
IL139240A0 (en) 2001-11-25
JP4452403B2 (en) 2010-04-21
NO20005722L (en) 2001-01-15
PL194347B1 (en) 2007-05-31
PT1077684E (en) 2003-12-31
BR9910454A (en) 2001-01-02
NO20005722D0 (en) 2000-11-13
EP1077684A1 (en) 2001-02-28
UY25510A1 (en) 1999-12-13
HN1999000067A (en) 1999-09-29
EP1077684B1 (en) 2003-08-06
DE19822036A1 (en) 1999-11-18
HUP0101822A2 (en) 2002-03-28
KR100629817B1 (en) 2006-09-29
EE200000650A (en) 2002-04-15
ID27441A (en) 2001-04-12
CO4830457A1 (en) 1999-08-30

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Owner name: BAYER HEALTHCARE AG, DE

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Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE

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Owner name: BAYER PHARMA AG, DE

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Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

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