CA2331671A1 - Effervescent preparations - Google Patents

Effervescent preparations Download PDF

Info

Publication number
CA2331671A1
CA2331671A1 CA002331671A CA2331671A CA2331671A1 CA 2331671 A1 CA2331671 A1 CA 2331671A1 CA 002331671 A CA002331671 A CA 002331671A CA 2331671 A CA2331671 A CA 2331671A CA 2331671 A1 CA2331671 A1 CA 2331671A1
Authority
CA
Canada
Prior art keywords
effervescent preparations
sugar
preparations
medicament
effervescent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002331671A
Other languages
French (fr)
Other versions
CA2331671C (en
Inventor
Reinhard Walter
Petra Ohage-Spitzlei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Intellectual Property GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2331671A1 publication Critical patent/CA2331671A1/en
Application granted granted Critical
Publication of CA2331671C publication Critical patent/CA2331671C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Abstract

Medicament-containing effervescent preparations are particularly stable on storage when they contain fusible sugar, sugar alcohol and/or sugar substitute.
CA002331671A 1998-05-15 1999-05-03 Effervescent preparations Expired - Lifetime CA2331671C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19822036.7 1998-05-15
DE19822036A DE19822036A1 (en) 1998-05-15 1998-05-15 Effervescent pharmaceutical composition with improved stability
PCT/EP1999/002969 WO1999059553A1 (en) 1998-05-15 1999-05-03 Effervescent preparations

Publications (2)

Publication Number Publication Date
CA2331671A1 true CA2331671A1 (en) 1999-11-25
CA2331671C CA2331671C (en) 2008-01-08

Family

ID=7868010

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002331671A Expired - Lifetime CA2331671C (en) 1998-05-15 1999-05-03 Effervescent preparations

Country Status (30)

Country Link
EP (1) EP1077684B1 (en)
JP (1) JP4452403B2 (en)
KR (1) KR100629817B1 (en)
AR (1) AR016473A1 (en)
AT (1) ATE246494T1 (en)
AU (1) AU3929799A (en)
BR (1) BR9910454A (en)
CA (1) CA2331671C (en)
CO (1) CO4830457A1 (en)
CZ (1) CZ300778B6 (en)
DE (2) DE19822036A1 (en)
DK (1) DK1077684T3 (en)
EE (1) EE04701B1 (en)
ES (1) ES2203134T3 (en)
GT (1) GT199900062A (en)
HN (1) HN1999000067A (en)
HR (1) HRP20000781B1 (en)
HU (1) HU224034B1 (en)
ID (1) ID27441A (en)
IL (1) IL139240A (en)
NO (1) NO20005722L (en)
PA (1) PA8472001A1 (en)
PE (1) PE20000465A1 (en)
PL (1) PL194347B1 (en)
PT (1) PT1077684E (en)
SI (1) SI1077684T1 (en)
SK (1) SK284621B6 (en)
TR (1) TR200003357T2 (en)
UY (1) UY25510A1 (en)
WO (1) WO1999059553A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001254826B2 (en) * 2000-04-20 2006-03-16 Ethypharm Effervescent granules and methods for their preparation
US20180360737A1 (en) * 2015-12-12 2018-12-20 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
US11576855B2 (en) 2014-09-17 2023-02-14 Steerlife India Private Limited Effervescent composition and method of making it

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU777234B2 (en) * 1999-02-11 2004-10-07 Hexal Ag Pharmaceutical effervescent formulation containing metamizol
FR2823668B1 (en) * 2001-04-20 2004-02-27 Ethypharm Lab Prod Ethiques ORODISPERSIBLE EFFERVESCENT TABLETS
EA010751B1 (en) * 2005-02-03 2008-10-30 Никомед Фарма Ас Melt granulation of a composition containing a calcium-containing compound
GR1007299B (en) * 2010-03-24 2011-06-06 Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε, Original effervescent hydrochloric metformin composition in the form of tablets
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2017011326A1 (en) * 2015-07-10 2017-01-19 Sanjay Gupta Nasal foam via cribriform plate for medication delivery to the brain and/or body and for nasal moisturization and hygiene
JP2018183067A (en) * 2017-04-24 2018-11-22 株式会社松原製餡所 Expandable additive and bean jam food product

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004036A (en) * 1966-05-31 1977-01-18 Alberto Culver Company Effervescent molded triturate tablets
US3653914A (en) * 1970-03-20 1972-04-04 Alberto Culver Co Production of tablets
DE69102900T3 (en) * 1990-02-14 1998-04-09 Takeda Chemical Industries Ltd Shower mix, its production and use.
RU2096955C1 (en) * 1991-03-01 1997-11-27 Е.И.Дюпон Де Немур Энд Компани Water-dispersable granulated pesticide composition prepared by extrusion method and a method of its preparing
MX9300110A (en) * 1992-01-13 1994-07-29 Gerhard Gergely PHARMACEUTICAL PREPARATION IN THE FORM OF AN EFFERVESCENCE OR DISINTEGRATION TABLET OR OF AN INSTANT-TYPE GRANULATE AND PROCEDURE FOR ITS PREPARATION.
HU217125B (en) * 1993-03-10 1999-11-29 Béres Rt. Sugar- and sodium-free effervescens tablets and granules and process for producing them
CZ285475B6 (en) * 1993-09-09 1999-08-11 Gerhard Gergely Granulate for preparing effervescent pharmaceutical preparation and process for producing thereof
GB2307857B (en) * 1995-12-04 1999-01-27 Euro Celtique Sa An effervescent formulation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001254826B2 (en) * 2000-04-20 2006-03-16 Ethypharm Effervescent granules and methods for their preparation
CN100337613C (en) * 2000-04-20 2007-09-19 爱的发 Effervescence particles and preparing method thereof
US11576855B2 (en) 2014-09-17 2023-02-14 Steerlife India Private Limited Effervescent composition and method of making it
US20180360737A1 (en) * 2015-12-12 2018-12-20 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof

Also Published As

Publication number Publication date
HUP0101822A3 (en) 2002-12-28
PA8472001A1 (en) 2000-09-29
ID27441A (en) 2001-04-12
HRP20000781A2 (en) 2001-06-30
EP1077684A1 (en) 2001-02-28
SK284621B6 (en) 2005-07-01
SK17062000A3 (en) 2001-04-09
PL344140A1 (en) 2001-10-08
EP1077684B1 (en) 2003-08-06
PL194347B1 (en) 2007-05-31
WO1999059553A1 (en) 1999-11-25
NO20005722D0 (en) 2000-11-13
PE20000465A1 (en) 2000-07-07
HU224034B1 (en) 2005-05-30
BR9910454A (en) 2001-01-02
HN1999000067A (en) 1999-09-29
SI1077684T1 (en) 2003-12-31
JP4452403B2 (en) 2010-04-21
NO20005722L (en) 2001-01-15
HRP20000781B1 (en) 2010-06-30
DE19822036A1 (en) 1999-11-18
GT199900062A (en) 2000-10-20
DE59906519D1 (en) 2003-09-11
AR016473A1 (en) 2001-07-04
HUP0101822A2 (en) 2002-03-28
CZ300778B6 (en) 2009-08-12
IL139240A0 (en) 2001-11-25
ATE246494T1 (en) 2003-08-15
JP2002515422A (en) 2002-05-28
ES2203134T3 (en) 2004-04-01
AU3929799A (en) 1999-12-06
IL139240A (en) 2005-08-31
EE200000650A (en) 2002-04-15
DK1077684T3 (en) 2003-11-17
EE04701B1 (en) 2006-10-16
UY25510A1 (en) 1999-12-13
CZ20004171A3 (en) 2001-03-14
CA2331671C (en) 2008-01-08
KR100629817B1 (en) 2006-09-29
TR200003357T2 (en) 2001-05-21
PT1077684E (en) 2003-12-31
KR20010043600A (en) 2001-05-25
CO4830457A1 (en) 1999-08-30

Similar Documents

Publication Publication Date Title
CA2161004A1 (en) Active ingredient patch
CA2180816A1 (en) 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
CA2193337A1 (en) 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients
AU5932198A (en) Polyesteramide, its preparation and surgical devices fabricated therefrom
AU1393000A (en) 1,4-diazabicyclo(3.2.2)nonane derivatives, their preparation and therapeutic application
AU2034395A (en) Composition consisting of a dendrimer and an active substance occluded in the dendrimer, a process for the preparation of such a composition and a process for releasing the active substance
ZA979585B (en) Pesticidal methods, compositions and devices.
EP0645136A3 (en) Physiologically active substance-prolonged releasing-type pharmaceutical preparation.
AU5651696A (en) Substituted 1-phenyl-3-pyrazolecarboxamides active on nurotensin receptors, their preparation and pharmaceutical compositions containing them
AU4679297A (en) 3-hydroxypyridine-2-carboxamidoesters, their preparation and their use as pharmaceuticals
AU8541598A (en) Pharmaceutical composition containing polyphenols from grapes, in particular resveratrol, and yeast extracts
AU3480297A (en) Modified mcm-56, its preparation and use
ZA968304B (en) Noval amino acid derivatives, their preparation and use.
ZA200007415B (en) Amino acid derivatives and drugs containing the same as the active ingredient.
AU6408898A (en) Antimicrobial compositions, their preparation and use
CA2331671A1 (en) Effervescent preparations
ZA9711169B (en) Pyrrole derivatives, their preparation and pharmaceutical compositions containing them.
AU2178597A (en) Pyrazoles and agricultural chemicals containing them as active ingredients
AU4330796A (en) Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz(b,f)oxepines
IL121969A0 (en) 10,13,15-trioxatricyclo[9.2.1.1.9.6]-pentadecanone derivatives their preparation and pharmaceutical compositions containing them
AU2002333373A1 (en) Combined preparations, containing 1,4-benzothiepine-1,1-dioxide derivatives and other active substances, and the use thereof
AU4806497A (en) Glyoxylic compound comprising one or more active ingredient
AU1650501A (en) 1,3,4-oxadiazoline derivatives and drugs containing these derivatives as the active ingredient
AU2651297A (en) Indolyl-substituted uracil derivatives and herbicides comprising them as active ingredients
AU3266197A (en) Transdermic systems containing 2 active ingredients in separate compartments, their preparation process and their use as medicaments

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20190503