ES2150890T1 - Sintesis de oligosacaridos. - Google Patents

Sintesis de oligosacaridos.

Info

Publication number
ES2150890T1
ES2150890T1 ES97935368T ES97935368T ES2150890T1 ES 2150890 T1 ES2150890 T1 ES 2150890T1 ES 97935368 T ES97935368 T ES 97935368T ES 97935368 T ES97935368 T ES 97935368T ES 2150890 T1 ES2150890 T1 ES 2150890T1
Authority
ES
Spain
Prior art keywords
synthesis
glycoside
oligosaccharides
solid phase
oligosaccharids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES97935368T
Other languages
English (en)
Other versions
ES2150890T3 (es
Inventor
Istvan Toth
Gyula Dekany
Barry Kellam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alchemia Pty Ltd
Original Assignee
Alchemia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alchemia Pty Ltd filed Critical Alchemia Pty Ltd
Publication of ES2150890T1 publication Critical patent/ES2150890T1/es
Application granted granted Critical
Publication of ES2150890T3 publication Critical patent/ES2150890T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION PROPORCIONA UN SISTEMA DE SINTESIS EN FASE SOLIDA DE OLIGOSACARIDOS, BASADO EN EL DESCUBRIMIENTO DE QUE SE PUEDE EMPLEAR UN GRUPO DE UNION DE 1,3 - DIOXOCICLOALQUILO SUSTITUIDO EN POSICION 2, DE FORMULA GENERAL (I), PARA ENLAZAR GRUPOS SACARIDOS, TANTO DE TIPO O - GLICOSIDO COMO N - GLICOSIDO, A UN SOPORTE POLIMERICO. LA INVENCION PROPORCIONA REACTIVOS, EQUIPAMIENTOS DE REACTIVOS Y PROCEDIMIENTOS DE SINTESIS DE OLIGOSACARIDOS EN FASE SOLIDA.
ES97935368T 1996-08-26 1997-08-26 Sintesis de oligosacaridos. Expired - Lifetime ES2150890T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPO1905A AUPO190596A0 (en) 1996-08-26 1996-08-26 Oligosaccharide synthesis

Publications (2)

Publication Number Publication Date
ES2150890T1 true ES2150890T1 (es) 2000-12-16
ES2150890T3 ES2150890T3 (es) 2003-07-01

Family

ID=3796218

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97935368T Expired - Lifetime ES2150890T3 (es) 1996-08-26 1997-08-26 Sintesis de oligosacaridos.

Country Status (12)

Country Link
US (2) US6573337B1 (es)
EP (1) EP0923528B1 (es)
JP (1) JP2001501174A (es)
CN (1) CN1121375C (es)
AT (1) ATE227258T1 (es)
AU (1) AUPO190596A0 (es)
CA (1) CA2264390A1 (es)
DE (2) DE923528T1 (es)
DK (1) DK0923528T3 (es)
ES (1) ES2150890T3 (es)
HU (1) HUP0000069A3 (es)
WO (1) WO1998008799A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO190596A0 (en) * 1996-08-26 1996-09-19 Alchemia Pty Ltd Oligosaccharide synthesis
AUPO536797A0 (en) * 1997-02-28 1997-03-20 Alchemia Pty Ltd Protected aminosugars
AUPO937597A0 (en) * 1997-09-24 1997-10-16 Alchemia Pty Ltd Protecting and linking groups for organic synthesis
AUPP823099A0 (en) 1999-01-18 1999-02-11 Alchemia Pty Ltd Protecting groups for carbohydrate synthesis
US6476191B1 (en) * 1999-02-05 2002-11-05 Mixture Sciences, Inc. Volatilizable solid phase supports for compound synthesis
US20010051349A1 (en) 2000-02-17 2001-12-13 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
EP1175427B1 (en) 1999-03-05 2010-08-18 Massachusetts Institute Of Technology Linkers for synthesis of oligosaccharides on solid supports
DE60110094T2 (de) * 2000-08-18 2009-10-01 Massachusetts Institute Of Technology, Cambridge Vorrichtung und verfahren zur automatisierten synthese von oligosacchariden
US7723296B2 (en) 2001-01-18 2010-05-25 Genzyme Corporation Methods for introducing mannose-6-phosphate and other oligosaccharides onto glycoproteins and its application thereof
AUPS143402A0 (en) * 2002-03-28 2002-05-09 Alchemia Pty Ltd Anomeric derivatives of monosaccharides
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
CN101631794B (zh) * 2007-01-18 2013-01-02 建新公司 包含氨基氧基基团的寡糖及其轭合物
US8614314B2 (en) 2008-05-30 2013-12-24 Momenta Pharmaceuticals, Inc. Saccharide structures and methods of making and using such structures
CN103432566A (zh) 2008-12-16 2013-12-11 建新公司 寡糖-蛋白缀合物

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1339748A (en) 1970-07-02 1973-12-05 Ici Ltd Pyrimidine derivatives
US4062950A (en) 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
JPS5829281B2 (ja) 1974-06-04 1983-06-22 日本曹達株式会社 バルビツ−ル酸系除草剤
PL103086B1 (pl) 1976-05-06 1979-05-31 Ciba Geigy Ag Srodek owadobojczy
DE2832698A1 (de) 1978-07-26 1980-02-07 Bayer Ag Substituierte 5-phenylcarbamoyl- barbitursaeuren, verfahren zu ihrer herstellung und ihre verwendung als insektizide
US4283444A (en) 1978-09-12 1981-08-11 Ciba-Geigy Corporation Method of protecting keratinous material from attack by insects that feed on keratin by treatment with 5-phenylcarbamoylbarbituric acid compounds
CH654720A5 (de) 1981-09-03 1986-03-14 Ciba Geigy Ag Lagerstabile mottenschutzformulierungen.
CH658770A5 (de) 1982-08-26 1986-12-15 Ciba Geigy Ag Motten- und kaeferschutzmittel.
GB2145087B (en) 1983-08-19 1987-02-04 Ciba Geigy Ag Barbituric acid derivatives
CH657015A5 (de) 1984-06-27 1986-08-15 Ciba Geigy Ag Motten- und kaeferschutzmittel.
US4753940A (en) 1985-02-15 1988-06-28 Ciba-Geigy Corporation Barbituric acid derivatives
PH24423A (en) 1985-02-15 1990-06-25 Ciba Geigy Ag 5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives as anthelmintics
US4742128A (en) 1985-10-15 1988-05-03 Stamicarbon B.V. Process for preparing a polymer alloy, molded product, and reaction injection molded products
US4797147A (en) 1986-06-09 1989-01-10 Stauffer Chemical Company Herbicidal method and composition utilizing certain 5-(2-substituted benzoyl)-barbituric acids
US4938796A (en) 1987-07-06 1990-07-03 Ici Americas Inc. Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor
DE3903404A1 (de) 1989-02-06 1990-08-09 Hoechst Ag Pyrimidintrionderivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als schaedlingsbekaempfungsmittel
US5959109A (en) 1996-05-15 1999-09-28 Neurocrine Biosciences, Inc. Compounds and methods for increasing endogenous levels of corticotropin-releasing factor
AUPO190596A0 (en) * 1996-08-26 1996-09-19 Alchemia Pty Ltd Oligosaccharide synthesis
AUPO536797A0 (en) * 1997-02-28 1997-03-20 Alchemia Pty Ltd Protected aminosugars
BR9810450A (pt) 1997-06-21 2000-09-05 Roche Diagnostics Gmbh Derivados de ácido barbitúrico com atividade antimetastática e antitumor
CN1276788A (zh) 1997-09-24 2000-12-13 阿尔开密亚有限公司 用于有机合成的保护和连接基团
AUPP823099A0 (en) 1999-01-18 1999-02-11 Alchemia Pty Ltd Protecting groups for carbohydrate synthesis

Also Published As

Publication number Publication date
CN1121375C (zh) 2003-09-17
HUP0000069A2 (hu) 2000-05-28
ATE227258T1 (de) 2002-11-15
US6573337B1 (en) 2003-06-03
EP0923528B1 (en) 2002-11-06
EP0923528A4 (en) 2000-07-19
EP0923528A1 (en) 1999-06-23
CN1234790A (zh) 1999-11-10
DE69716931T2 (de) 2003-07-31
HUP0000069A3 (en) 2002-04-29
JP2001501174A (ja) 2001-01-30
DK0923528T3 (da) 2003-03-10
WO1998008799A1 (en) 1998-03-05
CA2264390A1 (en) 1998-03-05
US6723843B2 (en) 2004-04-20
ES2150890T3 (es) 2003-07-01
AUPO190596A0 (en) 1996-09-19
US20030027925A1 (en) 2003-02-06
DE69716931D1 (de) 2002-12-12
DE923528T1 (de) 2001-03-01

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