ES2149913T3 - Antigenos de toxoplasma gondii, su preparacion y su utilizacion. - Google Patents

Antigenos de toxoplasma gondii, su preparacion y su utilizacion.

Info

Publication number
ES2149913T3
ES2149913T3 ES95117643T ES95117643T ES2149913T3 ES 2149913 T3 ES2149913 T3 ES 2149913T3 ES 95117643 T ES95117643 T ES 95117643T ES 95117643 T ES95117643 T ES 95117643T ES 2149913 T3 ES2149913 T3 ES 2149913T3
Authority
ES
Spain
Prior art keywords
antigens
toxoplasma gondii
preparation
gondii
cadn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95117643T
Other languages
English (en)
Inventor
Stefan Dr Knapp
Robert Dr Ziegelmaier
Hans Dr Kupper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Application granted granted Critical
Publication of ES2149913T3 publication Critical patent/ES2149913T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/45—Toxoplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE LA IDENTIFICACION Y OBTENCION POR TECNOLOGIA GENETICA DE ANTIGENOS DE TOXOPLASMA GONDII. DE ESTE GERMEN SE OBTUVO UN BANCO DE GENES DE EXPRESION DE CADN. CLONES RECOMBINANTES, QUE SON DE INTERES PARA EL DIAGNOSTICO, SE IDENTIFICARON Y AISLARON CON UN SUERO DE CONEJO DE ELEVADA VALORACION ANTI-TOXOPLASMA GONDII.
ES95117643T 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion. Expired - Lifetime ES2149913T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3940598A DE3940598A1 (de) 1989-12-08 1989-12-08 Toxoplasma gondii-antigene, ihre herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ES2149913T3 true ES2149913T3 (es) 2000-11-16

Family

ID=6395070

Family Applications (4)

Application Number Title Priority Date Filing Date
ES95117643T Expired - Lifetime ES2149913T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES95117644T Expired - Lifetime ES2152357T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES90123152T Expired - Lifetime ES2092483T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES95117642T Expired - Lifetime ES2161817T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES95117644T Expired - Lifetime ES2152357T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES90123152T Expired - Lifetime ES2092483T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES95117642T Expired - Lifetime ES2161817T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.

Country Status (13)

Country Link
US (3) US6022546A (es)
EP (4) EP0751147B1 (es)
JP (4) JP3085972B2 (es)
KR (2) KR100215607B1 (es)
AT (4) ATE196162T1 (es)
AU (1) AU629074B2 (es)
CA (1) CA2031811C (es)
DE (5) DE3940598A1 (es)
DK (1) DK0431541T3 (es)
ES (4) ES2149913T3 (es)
GR (1) GR3020819T3 (es)
IE (1) IE75375B1 (es)
PT (1) PT96097B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542843A4 (en) * 1990-08-10 1994-07-06 Univ Southern Australia Cloning and expression of toxoplasma antigens and use of recombinant antigens
GB9027728D0 (en) * 1990-12-20 1991-02-13 Smithkline Beecham Biolog Novel protein
FR2692282B1 (fr) * 1992-06-15 1995-07-13 Pasteur Institut Clonage du gene codant pour la proteine gp28.5 de t. gondii; fragments peptidiques issus de ladite proteine et leurs applications.
AU6172194A (en) * 1993-02-08 1994-08-29 Paravax, Inc. Defective sindbis virus vectors that express (toxoplasma gondii) p30 antigens
ZA958366B (en) * 1994-10-06 1996-04-24 Akzo Nobel Nv New toxoplasma gondii antigens
JP2000506376A (ja) * 1996-01-26 2000-05-30 イノジェネティックス・ナムローゼ・フェンノートシャップ トキソプラズマ・ゴンジイ抗原Ｔｇ２０
EP0953641A3 (en) * 1998-03-26 2002-03-13 Pfizer Products Inc. Polynucleotide molecules encoding neospora proteins
AU2006202355B2 (en) * 1998-05-01 2009-08-20 Glaxosmithkline Biologicals Sa Neisseria meningitidis antigens and compositions
EP1082343A2 (en) * 1998-05-28 2001-03-14 Abbott Laboratories Toxoplasma gondii antigens, p35, and uses thereof
US6329157B1 (en) 1998-05-28 2001-12-11 Abbott Laboratories Antigen cocktails and uses thereof
AU4825699A (en) * 1998-06-19 2000-01-05 Genzyme Corporation Identification and use of differentially expressed genes and polynucleotide sequences
AU2003219541A1 (en) * 2002-03-21 2003-10-08 Kenton S.R.L. Antigen fragments for the diagnosis of toxoplasma gondii
US7094879B2 (en) 2002-10-02 2006-08-22 Abbott Laboratories Genetically engineered P30 antigen, improved antigen cocktail, and uses thereof
JP4292847B2 (ja) 2003-03-31 2009-07-08 マツダ株式会社 車両のリアバンパー構造
KR20080003330A (ko) 2005-03-08 2008-01-07 켄톤 에스.알.엘. 톡소포자충의 키메릭 재조합 항원
US7432046B2 (en) 2005-11-02 2008-10-07 Abbott Laboratories Methods for the determination of antibody IgG avidity
WO2008051285A2 (en) 2006-04-01 2008-05-02 Medical Service Consultation International, Llc Methods and compositions for detecting fungi and mycotoxins
US20100068718A1 (en) 2008-08-22 2010-03-18 Hooper Dennis G Methods and Compositions for Identifying Yeast
CN103517714A (zh) * 2010-12-23 2014-01-15 英珀特疗法有限公司 用于刚地弓形虫感染和弓形体病的诊断和治疗的方法和蛋白抗原组合物
CN102313811A (zh) * 2011-09-19 2012-01-11 厦门市仙岳医院 弓形虫IgG抗体胶体金免疫层析检测试剂条及制备方法
CN102305861B (zh) * 2011-09-19 2014-06-18 厦门大学附属中山医院 弓形虫IgM与IgG抗体联合检测试剂条及其制备方法
CN103235119B (zh) * 2013-04-11 2015-09-16 南京农业大学 一种用于弓形虫感染的诊断抗原的应用
KR101682406B1 (ko) * 2016-08-12 2016-12-05 신영기술개발(주) 교량 선배수관 시공방법
CN111116726A (zh) * 2020-01-14 2020-05-08 中国农业科学院北京畜牧兽医研究所 用于检测弓形虫的重组蛋白及其编码基因
CN111265659A (zh) * 2020-02-28 2020-06-12 南京农业大学 一种刚地弓形虫纳米材料亚单位疫苗及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2618680B1 (fr) * 1987-07-31 1990-05-11 Pasteur Institut Antigenes d'excretion-secretion specifiques de toxoplasma gondii, leurs produits d'expression, leur procede d'obtention et leurs applications diagnostiques et prophylactiques
FR2625099B1 (fr) * 1987-12-24 1991-06-14 Transgene Sa Proteines et leur procede de preparation, sequences d'adn, anticorps et leur application, poxvirus, cellules transformees ou infectees et compositions pharmaceutiques utiles dans la prevention de la toxoplasmose
US4877726A (en) * 1988-03-02 1989-10-31 Research Institute Of Palo Alto Medical Foundation Method for the detection of acute-phase toxoplasma infection
DE68926658T2 (de) * 1988-03-09 1996-11-28 Univ Leland Stanford Junior Diagnostische gene zum nachweis von toxoplasmose
US5429922A (en) * 1988-03-09 1995-07-04 The Board Of Trustees Of The Leland Stanford Junior University Composition and method for distinguishing virulent and non-virulent toxoplasma infections

Also Published As

Publication number Publication date
DE59010925D1 (de) 2001-11-08
PT96097A (pt) 1991-09-30
KR100215606B1 (en) 1999-08-16
PT96097B (pt) 1998-02-27
EP0748815B1 (de) 2001-10-04
US6419925B1 (en) 2002-07-16
ATE196162T1 (de) 2000-09-15
DE59010913D1 (de) 2000-10-12
DE59010450D1 (de) 1996-09-19
ATE197068T1 (de) 2000-11-15
JP3366628B2 (ja) 2003-01-14
JP3085972B2 (ja) 2000-09-11
US6022546A (en) 2000-02-08
KR910012244A (ko) 1991-08-07
IE904426A1 (en) 1991-06-19
AU6781990A (en) 1991-06-13
EP0751147B1 (de) 2000-09-06
EP0431541A3 (en) 1992-04-22
ATE141289T1 (de) 1996-08-15
US6326008B1 (en) 2001-12-04
JP3245143B2 (ja) 2002-01-07
AU629074B2 (en) 1992-09-24
CA2031811A1 (en) 1991-06-09
EP0748815A1 (de) 1996-12-18
GR3020819T3 (en) 1996-11-30
ATE206435T1 (de) 2001-10-15
KR100215607B1 (ko) 1999-08-16
ES2152357T3 (es) 2001-02-01
EP0431541B1 (de) 1996-08-14
DE59010915D1 (de) 2000-11-23
IE75375B1 (en) 1997-09-10
ES2161817T3 (es) 2001-12-16
EP0431541A2 (de) 1991-06-12
JP2002010793A (ja) 2002-01-15
JP2002010794A (ja) 2002-01-15
JP2000308495A (ja) 2000-11-07
DK0431541T3 (da) 1997-01-06
JPH03197497A (ja) 1991-08-28
DE3940598A1 (de) 1991-06-13
EP0751147A1 (de) 1997-01-02
EP0748816B1 (de) 2000-10-18
JP3390749B2 (ja) 2003-03-31
EP0748816A1 (de) 1996-12-18
ES2092483T3 (es) 1996-12-01
CA2031811C (en) 2003-05-06

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