ES2092483T3 - Antigenos de toxoplasma gondii, su preparacion y su utilizacion. - Google Patents

Antigenos de toxoplasma gondii, su preparacion y su utilizacion.

Info

Publication number
ES2092483T3
ES2092483T3 ES90123152T ES90123152T ES2092483T3 ES 2092483 T3 ES2092483 T3 ES 2092483T3 ES 90123152 T ES90123152 T ES 90123152T ES 90123152 T ES90123152 T ES 90123152T ES 2092483 T3 ES2092483 T3 ES 2092483T3
Authority
ES
Spain
Prior art keywords
antigens
preparation
gondii
toxoplasma gondii
toxone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90123152T
Other languages
English (en)
Inventor
Stefan Dr Knapp
Robert Dr Ziegelmaier
Hans Dr Kupper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2092483T3 publication Critical patent/ES2092483T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/45—Toxoplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE LA IDENTIFICACION Y ELABORACION POR TECNOLOGIA GEN DE PLASMAS DE TOXONA GONDII-ANTIGENO. DE ESTE GERMEN SE ELABORA UN CDNA-BANCO DE EXPRESION. RECOMBINACIONES DE CLONO, QUE SON DE INTERES DIAGNOSTICO SE IDENTIFICAN Y SE AISLAN CON UN ALTO INDICE LOS ANTIPLASMAS DE TOXONA GONDII-SUERO DE CONEJO.
ES90123152T 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion. Expired - Lifetime ES2092483T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3940598A DE3940598A1 (de) 1989-12-08 1989-12-08 Toxoplasma gondii-antigene, ihre herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ES2092483T3 true ES2092483T3 (es) 1996-12-01

Family

ID=6395070

Family Applications (4)

Application Number Title Priority Date Filing Date
ES95117643T Expired - Lifetime ES2149913T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES95117642T Expired - Lifetime ES2161817T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES90123152T Expired - Lifetime ES2092483T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES95117644T Expired - Lifetime ES2152357T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES95117643T Expired - Lifetime ES2149913T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.
ES95117642T Expired - Lifetime ES2161817T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES95117644T Expired - Lifetime ES2152357T3 (es) 1989-12-08 1990-12-04 Antigenos de toxoplasma gondii, su preparacion y su utilizacion.

Country Status (13)

Country Link
US (3) US6022546A (es)
EP (4) EP0431541B1 (es)
JP (4) JP3085972B2 (es)
KR (2) KR100215607B1 (es)
AT (4) ATE206435T1 (es)
AU (1) AU629074B2 (es)
CA (1) CA2031811C (es)
DE (5) DE3940598A1 (es)
DK (1) DK0431541T3 (es)
ES (4) ES2149913T3 (es)
GR (1) GR3020819T3 (es)
IE (1) IE75375B1 (es)
PT (1) PT96097B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542843A4 (en) * 1990-08-10 1994-07-06 Univ Southern Australia Cloning and expression of toxoplasma antigens and use of recombinant antigens
GB9027728D0 (en) * 1990-12-20 1991-02-13 Smithkline Beecham Biolog Novel protein
FR2692282B1 (fr) * 1992-06-15 1995-07-13 Pasteur Institut Clonage du gene codant pour la proteine gp28.5 de t. gondii; fragments peptidiques issus de ladite proteine et leurs applications.
AU6172194A (en) * 1993-02-08 1994-08-29 Paravax, Inc. Defective sindbis virus vectors that express (toxoplasma gondii) p30 antigens
ZA958366B (en) * 1994-10-06 1996-04-24 Akzo Nobel Nv New toxoplasma gondii antigens
US6172192B1 (en) 1996-01-26 2001-01-09 Innogenetics N.V. Toxoplasma gondii antigen Tg20
EP0953641A3 (en) * 1998-03-26 2002-03-13 Pfizer Products Inc. Polynucleotide molecules encoding neospora proteins
AU2006202355B2 (en) * 1998-05-01 2009-08-20 Glaxosmithkline Biologicals Sa Neisseria meningitidis antigens and compositions
WO1999061906A2 (en) * 1998-05-28 1999-12-02 Abbott Laboratories Toxoplasma gondii antigens, p35, and uses thereof
US6329157B1 (en) 1998-05-28 2001-12-11 Abbott Laboratories Antigen cocktails and uses thereof
AU4825699A (en) * 1998-06-19 2000-01-05 Genzyme Corporation Identification and use of differentially expressed genes and polynucleotide sequences
US7176286B2 (en) * 2002-03-21 2007-02-13 Kenton S.R.L. Antigen fragments for the diagnosis of Toxoplasma gondii
US7094879B2 (en) 2002-10-02 2006-08-22 Abbott Laboratories Genetically engineered P30 antigen, improved antigen cocktail, and uses thereof
JP4292847B2 (ja) 2003-03-31 2009-07-08 マツダ株式会社 車両のリアバンパー構造
CN101137674A (zh) 2005-03-08 2008-03-05 肯顿有限公司 刚地弓形虫的嵌合重组抗原
US7432046B2 (en) 2005-11-02 2008-10-07 Abbott Laboratories Methods for the determination of antibody IgG avidity
WO2008051285A2 (en) 2006-04-01 2008-05-02 Medical Service Consultation International, Llc Methods and compositions for detecting fungi and mycotoxins
US20100068718A1 (en) 2008-08-22 2010-03-18 Hooper Dennis G Methods and Compositions for Identifying Yeast
EP2654782A4 (en) * 2010-12-23 2015-03-25 Immport Therapeutics Inc PROCESSES AND COMPOSITIONS FROM PROTEIN ANTIGEN FOR THE DIAGNOSIS AND TREATMENT OF TOXOPLASMA GONDII INFECTIONS AND TOXOPLASMOSIS
CN102313811A (zh) * 2011-09-19 2012-01-11 厦门市仙岳医院 弓形虫IgG抗体胶体金免疫层析检测试剂条及制备方法
CN102305861B (zh) * 2011-09-19 2014-06-18 厦门大学附属中山医院 弓形虫IgM与IgG抗体联合检测试剂条及其制备方法
CN103235119B (zh) * 2013-04-11 2015-09-16 南京农业大学 一种用于弓形虫感染的诊断抗原的应用
KR101682406B1 (ko) * 2016-08-12 2016-12-05 신영기술개발(주) 교량 선배수관 시공방법
CN111116726A (zh) * 2020-01-14 2020-05-08 中国农业科学院北京畜牧兽医研究所 用于检测弓形虫的重组蛋白及其编码基因
CN111265659A (zh) * 2020-02-28 2020-06-12 南京农业大学 一种刚地弓形虫纳米材料亚单位疫苗及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2618680B1 (fr) * 1987-07-31 1990-05-11 Pasteur Institut Antigenes d'excretion-secretion specifiques de toxoplasma gondii, leurs produits d'expression, leur procede d'obtention et leurs applications diagnostiques et prophylactiques
FR2625099B1 (fr) * 1987-12-24 1991-06-14 Transgene Sa Proteines et leur procede de preparation, sequences d'adn, anticorps et leur application, poxvirus, cellules transformees ou infectees et compositions pharmaceutiques utiles dans la prevention de la toxoplasmose
US4877726A (en) * 1988-03-02 1989-10-31 Research Institute Of Palo Alto Medical Foundation Method for the detection of acute-phase toxoplasma infection
DE68926658T2 (de) * 1988-03-09 1996-11-28 Univ Leland Stanford Junior Diagnostische gene zum nachweis von toxoplasmose
US5429922A (en) * 1988-03-09 1995-07-04 The Board Of Trustees Of The Leland Stanford Junior University Composition and method for distinguishing virulent and non-virulent toxoplasma infections

Also Published As

Publication number Publication date
JP2002010793A (ja) 2002-01-15
JP3085972B2 (ja) 2000-09-11
EP0431541A2 (de) 1991-06-12
DE3940598A1 (de) 1991-06-13
ES2149913T3 (es) 2000-11-16
ES2152357T3 (es) 2001-02-01
JP2000308495A (ja) 2000-11-07
EP0748815A1 (de) 1996-12-18
US6419925B1 (en) 2002-07-16
JP3366628B2 (ja) 2003-01-14
EP0751147A1 (de) 1997-01-02
DE59010450D1 (de) 1996-09-19
DK0431541T3 (da) 1997-01-06
ATE197068T1 (de) 2000-11-15
KR100215607B1 (ko) 1999-08-16
PT96097B (pt) 1998-02-27
GR3020819T3 (en) 1996-11-30
US6326008B1 (en) 2001-12-04
ATE206435T1 (de) 2001-10-15
JP2002010794A (ja) 2002-01-15
ES2161817T3 (es) 2001-12-16
EP0751147B1 (de) 2000-09-06
AU629074B2 (en) 1992-09-24
IE904426A1 (en) 1991-06-19
DE59010925D1 (de) 2001-11-08
DE59010915D1 (de) 2000-11-23
JP3245143B2 (ja) 2002-01-07
KR910012244A (ko) 1991-08-07
US6022546A (en) 2000-02-08
JPH03197497A (ja) 1991-08-28
ATE196162T1 (de) 2000-09-15
KR100215606B1 (en) 1999-08-16
EP0748816B1 (de) 2000-10-18
AU6781990A (en) 1991-06-13
EP0431541B1 (de) 1996-08-14
EP0431541A3 (en) 1992-04-22
EP0748815B1 (de) 2001-10-04
IE75375B1 (en) 1997-09-10
EP0748816A1 (de) 1996-12-18
CA2031811C (en) 2003-05-06
JP3390749B2 (ja) 2003-03-31
PT96097A (pt) 1991-09-30
DE59010913D1 (de) 2000-10-12
CA2031811A1 (en) 1991-06-09
ATE141289T1 (de) 1996-08-15

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