DK0476059T3 - Fremgangsmåder til forøgelse af modificeringshastigheden for metastabile bindinger - Google Patents

Fremgangsmåder til forøgelse af modificeringshastigheden for metastabile bindinger

Info

Publication number
DK0476059T3
DK0476059T3 DK90910051.3T DK90910051T DK0476059T3 DK 0476059 T3 DK0476059 T3 DK 0476059T3 DK 90910051 T DK90910051 T DK 90910051T DK 0476059 T3 DK0476059 T3 DK 0476059T3
Authority
DK
Denmark
Prior art keywords
rate
modification
increasing
methods
metastable
Prior art date
Application number
DK90910051.3T
Other languages
English (en)
Inventor
Paul M Booth
Michael J Powell
Anthony R Rees
Wonpyo Hong
Richard Titmas
Richard Massey
Original Assignee
Igen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Igen Inc filed Critical Igen Inc
Application granted granted Critical
Publication of DK0476059T3 publication Critical patent/DK0476059T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DK90910051.3T 1989-06-08 1990-06-07 Fremgangsmåder til forøgelse af modificeringshastigheden for metastabile bindinger DK0476059T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36407789A 1989-06-08 1989-06-08

Publications (1)

Publication Number Publication Date
DK0476059T3 true DK0476059T3 (da) 1996-07-29

Family

ID=23432905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90910051.3T DK0476059T3 (da) 1989-06-08 1990-06-07 Fremgangsmåder til forøgelse af modificeringshastigheden for metastabile bindinger

Country Status (10)

Country Link
EP (1) EP0476059B1 (da)
JP (2) JPH05503284A (da)
AT (1) ATE135013T1 (da)
AU (2) AU652342B2 (da)
CA (1) CA2018453A1 (da)
DE (1) DE69025761T2 (da)
DK (1) DK0476059T3 (da)
IL (1) IL94666A (da)
WO (1) WO1990015074A1 (da)
ZA (1) ZA904457B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236825A (en) * 1989-01-17 1993-08-17 Scripps Clinic And Research Foundation Polyvalent metal ion-containing antibody combining site catalysts
US5318897A (en) * 1989-04-25 1994-06-07 Igen, Inc. Monoclonal antibody and antibody components elicited to a polypeptide antigen ground state
US6235714B1 (en) * 1998-03-23 2001-05-22 Sudhir Paul Methods for identifying inducers and inhibitors of proteolytic antibodies, compositions and their uses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079152A (en) * 1987-05-28 1992-01-07 Scripps Clinic And Research Foundation Antibody combining sites that exhibit stereoselective synthase activity, and methods using the same
US4900674A (en) * 1987-05-28 1990-02-13 Scripps Clinic And Research Foundation Antibody combining sites that exhibit amide or ester synthase activity
ZA893284B (en) * 1988-05-04 1990-03-28 Igen Inc Peptide analogs and their use as haptens to elicit catalytic antibodies

Also Published As

Publication number Publication date
EP0476059B1 (en) 1996-03-06
DE69025761D1 (de) 1996-04-11
ZA904457B (en) 1992-02-26
AU652342B2 (en) 1994-08-25
AU5842490A (en) 1991-01-07
AU7903594A (en) 1995-03-30
CA2018453A1 (en) 1990-12-08
IL94666A (en) 1997-02-18
DE69025761T2 (de) 1996-07-18
ATE135013T1 (de) 1996-03-15
AU669310B2 (en) 1996-05-30
WO1990015074A1 (en) 1990-12-13
EP0476059A1 (en) 1992-03-25
EP0476059A4 (en) 1992-06-03
JPH05503284A (ja) 1993-06-03
JPH1180195A (ja) 1999-03-26

Similar Documents

Publication Publication Date Title
DK0970126T3 (da) Hidtil ukendt fremgangsmåde til fremstillingen af anti-humant antigen-receptorer og anvendelser deraf
DK0699755T3 (da) Fremgangsmåde til opnåelse af modificerede immunglobuliner med reduceret immunogenicitet af variable domæner i et murint antistof, præparater der indeholder disse
ATE109795T1 (de) Htlv-iii umhüllende peptiden.
DK0460076T3 (da) Genetisk manipulerede immunoglobuliner
NO961115L (no) Humane metabotrope glutamatreseptorsubtyper (HMR4, HMR6, HMR7) og relaterte DNA forbindelser
DK0620854T3 (da) Ekspression og oprensning af rekombinant opløselig vævsfaktor
DK121683D0 (da) Fremgangsmade til fremstilling af immunoenzymatiske konjugater
ES2129487T3 (es) Peptidos sinteticos, anticuerpos dirigidos contra ellos y su utilizacion.
WO1995021922A3 (en) Non-a, non-b, non-c, non-d, non-e hepatitis reagents and methods for their use
GR3018371T3 (en) Method for identifying or determining proteins and applications therefor.
DK0476059T3 (da) Fremgangsmåder til forøgelse af modificeringshastigheden for metastabile bindinger
ES8606411A1 (es) Procedimiento para la determinacion de fibrina
DK0744027T3 (da) Anvendelse af fremgangsmåder til identifikation af hydrofile signaloligopeptider
DK0728015T3 (da) Kombinatoriske polypeptidantigener
DK0994187T3 (da) Renin-aktivt stof omfattende humant prorenin og antistoffer mod prorenin-profragmentet
ATE69056T1 (de) Tgf-polypeptide, davon derivierte antigene oligopeptide, davon erhaltene antikoerper.