ATE135013T1 - Verfahren zur erhöhung der rate der modifikation metastabiler bindungen - Google Patents
Verfahren zur erhöhung der rate der modifikation metastabiler bindungenInfo
- Publication number
- ATE135013T1 ATE135013T1 AT90910051T AT90910051T ATE135013T1 AT E135013 T1 ATE135013 T1 AT E135013T1 AT 90910051 T AT90910051 T AT 90910051T AT 90910051 T AT90910051 T AT 90910051T AT E135013 T1 ATE135013 T1 AT E135013T1
- Authority
- AT
- Austria
- Prior art keywords
- rate
- meta
- modification
- increase
- stable bonds
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36407789A | 1989-06-08 | 1989-06-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE135013T1 true ATE135013T1 (de) | 1996-03-15 |
Family
ID=23432905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90910051T ATE135013T1 (de) | 1989-06-08 | 1990-06-07 | Verfahren zur erhöhung der rate der modifikation metastabiler bindungen |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0476059B1 (de) |
JP (2) | JPH05503284A (de) |
AT (1) | ATE135013T1 (de) |
AU (2) | AU652342B2 (de) |
CA (1) | CA2018453A1 (de) |
DE (1) | DE69025761T2 (de) |
DK (1) | DK0476059T3 (de) |
IL (1) | IL94666A (de) |
WO (1) | WO1990015074A1 (de) |
ZA (1) | ZA904457B (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5236825A (en) * | 1989-01-17 | 1993-08-17 | Scripps Clinic And Research Foundation | Polyvalent metal ion-containing antibody combining site catalysts |
US5318897A (en) * | 1989-04-25 | 1994-06-07 | Igen, Inc. | Monoclonal antibody and antibody components elicited to a polypeptide antigen ground state |
US6235714B1 (en) * | 1998-03-23 | 2001-05-22 | Sudhir Paul | Methods for identifying inducers and inhibitors of proteolytic antibodies, compositions and their uses |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5079152A (en) * | 1987-05-28 | 1992-01-07 | Scripps Clinic And Research Foundation | Antibody combining sites that exhibit stereoselective synthase activity, and methods using the same |
US4900674A (en) * | 1987-05-28 | 1990-02-13 | Scripps Clinic And Research Foundation | Antibody combining sites that exhibit amide or ester synthase activity |
ZA893284B (en) * | 1988-05-04 | 1990-03-28 | Igen Inc | Peptide analogs and their use as haptens to elicit catalytic antibodies |
-
1990
- 1990-06-07 WO PCT/US1990/003226 patent/WO1990015074A1/en active IP Right Grant
- 1990-06-07 IL IL9466690A patent/IL94666A/xx not_active IP Right Cessation
- 1990-06-07 DE DE69025761T patent/DE69025761T2/de not_active Expired - Fee Related
- 1990-06-07 EP EP90910051A patent/EP0476059B1/de not_active Expired - Lifetime
- 1990-06-07 CA CA002018453A patent/CA2018453A1/en not_active Abandoned
- 1990-06-07 JP JP2509096A patent/JPH05503284A/ja active Pending
- 1990-06-07 DK DK90910051.3T patent/DK0476059T3/da active
- 1990-06-07 AT AT90910051T patent/ATE135013T1/de not_active IP Right Cessation
- 1990-06-07 AU AU58424/90A patent/AU652342B2/en not_active Ceased
- 1990-06-08 ZA ZA904457A patent/ZA904457B/xx unknown
-
1994
- 1994-11-25 AU AU79035/94A patent/AU669310B2/en not_active Expired - Fee Related
-
1998
- 1998-06-24 JP JP10177601A patent/JPH1180195A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0476059A1 (de) | 1992-03-25 |
EP0476059B1 (de) | 1996-03-06 |
ZA904457B (en) | 1992-02-26 |
WO1990015074A1 (en) | 1990-12-13 |
DK0476059T3 (da) | 1996-07-29 |
JPH05503284A (ja) | 1993-06-03 |
DE69025761D1 (de) | 1996-04-11 |
AU5842490A (en) | 1991-01-07 |
JPH1180195A (ja) | 1999-03-26 |
CA2018453A1 (en) | 1990-12-08 |
DE69025761T2 (de) | 1996-07-18 |
AU7903594A (en) | 1995-03-30 |
AU669310B2 (en) | 1996-05-30 |
IL94666A (en) | 1997-02-18 |
AU652342B2 (en) | 1994-08-25 |
EP0476059A4 (en) | 1992-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EEIH | Change in the person of patent owner | ||
REN | Ceased due to non-payment of the annual fee |