NO970030L - Isolert nukleinsyresekvens som koder for et tumor-rejeksjonsantigen presentert av HLA-A2 - Google Patents
Isolert nukleinsyresekvens som koder for et tumor-rejeksjonsantigen presentert av HLA-A2Info
- Publication number
- NO970030L NO970030L NO970030A NO970030A NO970030L NO 970030 L NO970030 L NO 970030L NO 970030 A NO970030 A NO 970030A NO 970030 A NO970030 A NO 970030A NO 970030 L NO970030 L NO 970030L
- Authority
- NO
- Norway
- Prior art keywords
- hla
- nucleic acid
- tumor rejection
- acid sequence
- sequence encoding
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 102000025850 HLA-A2 Antigen Human genes 0.000 title abstract 2
- 108010074032 HLA-A2 Antigen Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical group 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 239000002243 precursor Substances 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Foreliggende oppfinnelse beskriver nukleinsyremole- kyler som koder for en antigenrejeksjonsforløper. Nærmere bestemt beskrives at tumorrejeksjonsantigenforløperen, eller "TRAP"en, bearbeides til minst ett tumorrejeksjons- antigen som presenteres av HLA-A2-molekyler. Konsekvenser av oppfinnelsen er også angitt.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27235194A | 1994-07-08 | 1994-07-08 | |
US08/370,319 US5856091A (en) | 1993-03-18 | 1995-01-10 | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
PCT/US1995/008153 WO1996001557A1 (en) | 1994-07-08 | 1995-06-27 | Isolated nucleic acid sequence coding for a tumor rejection antigen presented by hla-a2 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO970030D0 NO970030D0 (no) | 1997-01-06 |
NO970030L true NO970030L (no) | 1997-01-06 |
Family
ID=26955454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO970030A NO970030L (no) | 1994-07-08 | 1997-01-06 | Isolert nukleinsyresekvens som koder for et tumor-rejeksjonsantigen presentert av HLA-A2 |
Country Status (10)
Country | Link |
---|---|
US (2) | US5856091A (no) |
EP (1) | EP0772626A4 (no) |
JP (1) | JPH10503928A (no) |
CN (1) | CN1152251A (no) |
AU (1) | AU696738B2 (no) |
CA (1) | CA2194451A1 (no) |
FI (1) | FI970071A0 (no) |
NO (1) | NO970030L (no) |
NZ (1) | NZ289616A (no) |
WO (1) | WO1996001557A1 (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5856091A (en) * | 1993-03-18 | 1999-01-05 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US6013481A (en) * | 1993-07-22 | 2000-01-11 | Ludwig Institute For Cancer Research | Isolated, nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof |
JPH10505481A (ja) | 1994-04-22 | 1998-06-02 | アメリカ合衆国 | メラノーマ抗原 |
US5874560A (en) | 1994-04-22 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Melanoma antigens and their use in diagnostic and therapeutic methods |
US5821122A (en) * | 1995-06-07 | 1998-10-13 | Inserm (Institute Nat'l De La Sante Et De La Recherche . .) | Isolated nucleic acid molecules, peptides which form complexes with MHC molecule HLA-A2 and uses thereof |
US5674749A (en) * | 1996-03-26 | 1997-10-07 | Ludwig Institute For Cancer Research | Monoclonal antibodies which bind to tumor rejection antigen precursor melan-A, and uses thereof |
NZ333149A (en) * | 1996-06-25 | 2000-06-23 | Ludwig Inst Cancer Res | Brain glycogen phosphorylase tumour rejection antigen precursors including antibodies to and nucleic acids coding them also methods and products for diagnosing and treating conditions characterised by expression of a BGPTR antigen or precursor thereof |
US6080399A (en) * | 1998-04-23 | 2000-06-27 | Arch Development Corporation | Vaccine adjuvants for immunotherapy of melanoma |
WO2008039818A2 (en) | 2006-09-26 | 2008-04-03 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Modified t cell receptors and related materials and methods |
EP3511425A1 (en) * | 2012-07-12 | 2019-07-17 | Persimmune, Inc. | Personalized cancer vaccines and adoptive immune cell therapies |
WO2016010975A2 (en) * | 2014-07-15 | 2016-01-21 | Illumina, Inc. | Biochemically activated electronic device |
US10987045B2 (en) | 2015-09-14 | 2021-04-27 | Biosense Webster (Israel) Ltd. | Basket catheter with individual spine control |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3297893A (en) | 1963-09-19 | 1967-01-10 | Litz Co | Brush mechanisms |
US5487974A (en) * | 1992-12-22 | 1996-01-30 | Ludwig Institute For Cancer-Research | Method for detecting complexes containing human leukocyte antigen A2 (HLA-A2) molecules and a tyrosinase drived peptide on abnormal cells |
US5620886A (en) | 1993-03-18 | 1997-04-15 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US5856091A (en) * | 1993-03-18 | 1999-01-05 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US5874560A (en) * | 1994-04-22 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Melanoma antigens and their use in diagnostic and therapeutic methods |
-
1995
- 1995-01-10 US US08/370,319 patent/US5856091A/en not_active Expired - Lifetime
- 1995-06-27 WO PCT/US1995/008153 patent/WO1996001557A1/en not_active Application Discontinuation
- 1995-06-27 EP EP95925356A patent/EP0772626A4/en not_active Withdrawn
- 1995-06-27 AU AU29517/95A patent/AU696738B2/en not_active Ceased
- 1995-06-27 NZ NZ289616A patent/NZ289616A/en unknown
- 1995-06-27 CA CA002194451A patent/CA2194451A1/en not_active Abandoned
- 1995-06-27 CN CN95194017A patent/CN1152251A/zh active Pending
- 1995-06-27 JP JP8504333A patent/JPH10503928A/ja active Pending
-
1997
- 1997-01-06 NO NO970030A patent/NO970030L/no not_active Application Discontinuation
- 1997-01-07 FI FI970071A patent/FI970071A0/fi unknown
-
1999
- 1999-01-04 US US09/224,834 patent/US6201111B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0772626A1 (en) | 1997-05-14 |
FI970071A (fi) | 1997-01-07 |
FI970071A0 (fi) | 1997-01-07 |
US6201111B1 (en) | 2001-03-13 |
NO970030D0 (no) | 1997-01-06 |
NZ289616A (en) | 1997-12-19 |
EP0772626A4 (en) | 1997-09-10 |
WO1996001557A1 (en) | 1996-01-25 |
AU2951795A (en) | 1996-02-09 |
CN1152251A (zh) | 1997-06-18 |
CA2194451A1 (en) | 1996-01-25 |
US5856091A (en) | 1999-01-05 |
JPH10503928A (ja) | 1998-04-14 |
AU696738B2 (en) | 1998-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |