ES2149083B1 - Nueva formulacion para inhalacion. - Google Patents
Nueva formulacion para inhalacion.Info
- Publication number
- ES2149083B1 ES2149083B1 ES009800080A ES9800080A ES2149083B1 ES 2149083 B1 ES2149083 B1 ES 2149083B1 ES 009800080 A ES009800080 A ES 009800080A ES 9800080 A ES9800080 A ES 9800080A ES 2149083 B1 ES2149083 B1 ES 2149083B1
- Authority
- ES
- Spain
- Prior art keywords
- inhalation
- new formulation
- formulation
- casting
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 3
- 238000005266 casting Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229960005105 terbutaline sulfate Drugs 0.000 abstract 1
- KFVSLSTULZVNPG-UHFFFAOYSA-N terbutaline sulfate Chemical compound [O-]S([O-])(=O)=O.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1 KFVSLSTULZVNPG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Nueva formulación para inhalación de una composición de polvo seco que comprende sulfato de terbutalina y una sustancia portadora, ambos de los cuales están en forma finamente dividida, en donde la formulación tiene una densidad aparente determinada por colada de 0,28 a 0,38 g/ml, es útil en el tratamiento de trastornos respiratorios.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9700136A SE9700136D0 (sv) | 1997-01-20 | 1997-01-20 | New formulation |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2149083A1 ES2149083A1 (es) | 2000-10-16 |
ES2149083B1 true ES2149083B1 (es) | 2001-05-16 |
Family
ID=20405456
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98901619T Expired - Lifetime ES2217535T3 (es) | 1997-01-20 | 1998-01-13 | Nueva formulacion para inhalacion, con una densidad aparente de 0,28 a 0,38 g/ml determinada por colada, que comprende sulfato de terbutalina, un procedimiento para preparar la formulacion, y el uso de la misma. |
ES009800080A Expired - Fee Related ES2149083B1 (es) | 1997-01-20 | 1998-01-16 | Nueva formulacion para inhalacion. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98901619T Expired - Lifetime ES2217535T3 (es) | 1997-01-20 | 1998-01-13 | Nueva formulacion para inhalacion, con una densidad aparente de 0,28 a 0,38 g/ml determinada por colada, que comprende sulfato de terbutalina, un procedimiento para preparar la formulacion, y el uso de la misma. |
Country Status (30)
Country | Link |
---|---|
EP (1) | EP1014955B1 (es) |
JP (1) | JP2001509812A (es) |
KR (1) | KR100528415B1 (es) |
CN (1) | CN1195507C (es) |
AT (1) | ATE263552T1 (es) |
AU (1) | AU728768B2 (es) |
BE (1) | BE1012009A5 (es) |
BR (1) | BR9806893A (es) |
CA (1) | CA2277891C (es) |
CZ (1) | CZ295665B6 (es) |
DE (1) | DE69823045T2 (es) |
EE (1) | EE03950B1 (es) |
ES (2) | ES2217535T3 (es) |
FR (1) | FR2759905B1 (es) |
GR (1) | GR980100023A (es) |
HU (1) | HUP0000755A3 (es) |
ID (1) | ID21929A (es) |
IE (1) | IE980026A1 (es) |
IL (1) | IL130839A (es) |
IS (1) | IS2072B (es) |
NL (1) | NL1008020C2 (es) |
NO (1) | NO993540L (es) |
NZ (1) | NZ336595A (es) |
PL (1) | PL189551B1 (es) |
RU (1) | RU2180562C2 (es) |
SE (1) | SE9700136D0 (es) |
SK (1) | SK283943B6 (es) |
TR (1) | TR199901689T2 (es) |
UA (1) | UA57765C2 (es) |
WO (1) | WO1998031353A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI991582A1 (it) | 1999-07-16 | 2001-01-16 | Chiesi Farma Spa | Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala |
JP2001151673A (ja) * | 1999-09-06 | 2001-06-05 | Nikken Chem Co Ltd | 吸入用粉末製剤の製造方法 |
GB0009469D0 (en) | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
PE20011227A1 (es) | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
GB0012261D0 (en) * | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel process |
SE0200657D0 (sv) * | 2002-03-04 | 2002-03-04 | Astrazeneca Ab | Novel Formulation |
GB0219511D0 (en) | 2002-08-21 | 2002-10-02 | Norton Healthcare Ltd | Method of preparing dry powder inhalation compositions |
NZ538965A (en) | 2002-08-21 | 2006-11-30 | Norton Healthcare Ltd | Dry powder inhalation compositions |
DE102007049931A1 (de) | 2007-10-18 | 2009-04-23 | Pharmatech Gmbh | Vorrichtung und Verfahren zur kontinuierlichen Herstellung von sphärischen Pulveragglomeraten |
EP2255807A1 (en) | 2009-05-26 | 2010-12-01 | Sanofi-Aventis | Method of treating sleep disorders using the combination of eplivanserin and zolpidem |
US20110262502A1 (en) * | 2010-02-08 | 2011-10-27 | Prairie Pharmaceuticals LLC | Pulmonary delivery of 17-hydroxyprogesterone caproate (17-hpc) |
GB201305825D0 (en) | 2013-03-28 | 2013-05-15 | Vectura Ltd | New use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0072046B1 (en) * | 1981-07-24 | 1986-01-15 | FISONS plc | Inhalation drugs, methods for their production and pharmaceutical formulations containing them |
ATE17441T1 (de) * | 1981-07-24 | 1986-02-15 | Fisons Plc | Inhalierbare arzneimittel, verfahren zu deren herstellung und pharmazeutische formulierungen diese enthaltend. |
WO1995009615A1 (en) * | 1993-10-01 | 1995-04-13 | Astra Aktiebolag | Process i |
SE9603669D0 (sv) * | 1996-10-08 | 1996-10-08 | Astra Ab | New combination |
-
1997
- 1997-01-20 SE SE9700136A patent/SE9700136D0/xx unknown
-
1998
- 1998-01-13 UA UA99074045A patent/UA57765C2/uk unknown
- 1998-01-13 EE EEP199900293A patent/EE03950B1/xx not_active IP Right Cessation
- 1998-01-13 ES ES98901619T patent/ES2217535T3/es not_active Expired - Lifetime
- 1998-01-13 BR BR9806893-8A patent/BR9806893A/pt not_active Application Discontinuation
- 1998-01-13 RU RU99118586/14A patent/RU2180562C2/ru not_active IP Right Cessation
- 1998-01-13 AU AU57860/98A patent/AU728768B2/en not_active Ceased
- 1998-01-13 NL NL1008020A patent/NL1008020C2/nl not_active IP Right Cessation
- 1998-01-13 SK SK960-99A patent/SK283943B6/sk unknown
- 1998-01-13 NZ NZ336595A patent/NZ336595A/xx unknown
- 1998-01-13 JP JP53421998A patent/JP2001509812A/ja not_active Ceased
- 1998-01-13 AT AT98901619T patent/ATE263552T1/de not_active IP Right Cessation
- 1998-01-13 TR TR1999/01689T patent/TR199901689T2/xx unknown
- 1998-01-13 WO PCT/SE1998/000041 patent/WO1998031353A1/en active IP Right Grant
- 1998-01-13 DE DE69823045T patent/DE69823045T2/de not_active Expired - Fee Related
- 1998-01-13 KR KR10-1999-7006415A patent/KR100528415B1/ko not_active IP Right Cessation
- 1998-01-13 CN CNB988019019A patent/CN1195507C/zh not_active Expired - Fee Related
- 1998-01-13 CZ CZ19992558A patent/CZ295665B6/cs not_active IP Right Cessation
- 1998-01-13 CA CA002277891A patent/CA2277891C/en not_active Expired - Fee Related
- 1998-01-13 IL IL13083998A patent/IL130839A/en not_active IP Right Cessation
- 1998-01-13 PL PL98334526A patent/PL189551B1/pl not_active IP Right Cessation
- 1998-01-13 EP EP98901619A patent/EP1014955B1/en not_active Expired - Lifetime
- 1998-01-13 HU HU0000755A patent/HUP0000755A3/hu unknown
- 1998-01-14 GR GR980100023A patent/GR980100023A/el not_active IP Right Cessation
- 1998-01-15 BE BE9800030A patent/BE1012009A5/fr active
- 1998-01-16 FR FR9800460A patent/FR2759905B1/fr not_active Expired - Fee Related
- 1998-01-16 IE IE980026A patent/IE980026A1/en not_active Application Discontinuation
- 1998-01-16 ES ES009800080A patent/ES2149083B1/es not_active Expired - Fee Related
- 1998-01-30 ID IDW990662A patent/ID21929A/id unknown
-
1999
- 1999-07-06 IS IS5107A patent/IS2072B/is unknown
- 1999-07-19 NO NO993540A patent/NO993540L/no not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2149082B1 (es) | Nueva formulacion para inhalacion. | |
ES2148059B1 (es) | Nueva formulacion para inhalacion. | |
SE9700135D0 (sv) | New formulation | |
ES2149083B1 (es) | Nueva formulacion para inhalacion. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 20001016 Kind code of ref document: A1 Effective date: 20001016 |
|
FD1A | Patent lapsed |
Effective date: 20101018 |