ES2137516T3 - Composicion a base de ciclosporina y su procedimiento de fabricacion. - Google Patents
Composicion a base de ciclosporina y su procedimiento de fabricacion.Info
- Publication number
- ES2137516T3 ES2137516T3 ES95920275T ES95920275T ES2137516T3 ES 2137516 T3 ES2137516 T3 ES 2137516T3 ES 95920275 T ES95920275 T ES 95920275T ES 95920275 T ES95920275 T ES 95920275T ES 2137516 T3 ES2137516 T3 ES 2137516T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- cyclosporine
- manufacturing procedure
- composition based
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Abstract
SE REIVINDICA UN COMPUESTO QUE CONTIENE DE UN 1.0% A UN 40% EN PESO DE CICLOSPORINA A, DE UN 0.1% A UN 30% EN PESO DE UN EMULSIONANTE Y DE UN 5% A UN 8O% EN PESO DE UNA DEXTRINA POROSA, SOBRE LA BASE DEL PESO TOTAL DEL COMPUESTO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR19940012288 | 1994-06-01 | ||
PCT/KR1995/000059 WO1995032726A1 (en) | 1994-06-01 | 1995-05-19 | Cyclosporin containing composition and process for the preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2137516T3 true ES2137516T3 (es) | 1999-12-16 |
Family
ID=19384450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95920275T Expired - Lifetime ES2137516T3 (es) | 1994-06-01 | 1995-05-19 | Composicion a base de ciclosporina y su procedimiento de fabricacion. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5739105A (es) |
EP (1) | EP0756489B1 (es) |
JP (1) | JP2936209B2 (es) |
KR (1) | KR0163212B1 (es) |
CN (1) | CN1148224C (es) |
AT (1) | ATE183398T1 (es) |
AU (1) | AU2577295A (es) |
DE (1) | DE69511539T2 (es) |
DK (1) | DK0756489T3 (es) |
ES (1) | ES2137516T3 (es) |
GR (1) | GR3031568T3 (es) |
RU (1) | RU2119351C1 (es) |
WO (1) | WO1995032726A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9618952D0 (en) * | 1996-09-11 | 1996-10-23 | Sandoz Ltd | Process |
KR100241652B1 (ko) * | 1997-07-07 | 2000-03-02 | 김충섭 | 이푸리플라본의 경구 투여용 제제의 제조 방법 |
AU748334B2 (en) | 1997-10-16 | 2002-05-30 | Board Of Regents, The University Of Texas System | Models and treatments for cardiac hypertrophy in relation with NF-AT3 function |
TW581681B (en) * | 1998-02-20 | 2004-04-01 | Nektar Therapeutics | Liquid crystal forms of cyclosporin |
US7026290B1 (en) | 1998-12-30 | 2006-04-11 | Dexcel Ltd. | Dispersible concentrate for the delivery of cyclosprin |
EP1058539A1 (en) * | 1999-01-06 | 2000-12-13 | Korea Research Institute Of Chemical Technology | Method of preparing pharmaceutical active ingredient comprising water-insoluble drug and pharmaceutical composition for oral administration comprising the same |
US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
DK1142566T3 (da) * | 2000-04-07 | 2004-02-09 | Medidom Lab | Oftalmologiske formuleringer på basis af ciclosporin, hyaluronsyre og polysorbat |
GB0008785D0 (en) * | 2000-04-10 | 2000-05-31 | Novartis Ag | Organic compounds |
AR036852A1 (es) * | 2001-10-19 | 2004-10-06 | Isotechnika Inc | Preconcentrado de una microemulsion de analogos de ciclosporina, su metodo de preparacion y metodos para producir inmunosupresion |
US6979672B2 (en) * | 2002-12-20 | 2005-12-27 | Polichem, S.A. | Cyclosporin-based pharmaceutical compositions |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
ATE412400T1 (de) * | 2004-11-09 | 2008-11-15 | Novagali Pharma Sa | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
US7151085B2 (en) | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
EP1843724B1 (en) | 2005-02-02 | 2018-07-25 | Össur hf | Sensing systems and methods for monitoring gait dynamics |
GB0921528D0 (en) | 2009-12-09 | 2010-01-27 | Mast Carbon Internat Ltd | Carbon and its use in blood cleansing applications |
JP6200698B2 (ja) * | 2013-06-18 | 2017-09-20 | ニュートリー株式会社 | 嚥下造影検査食 |
EP4241760A1 (en) * | 2020-11-09 | 2023-09-13 | Scai Therapeutics Co., Ltd. | Solid material and dispersion composition containing same |
WO2022098122A1 (ko) * | 2020-11-09 | 2022-05-12 | 주식회사 스카이테라퓨틱스 | 고상의 사이클로스포린 a 및 이를 포함하는 분산 조성물 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8807505D0 (en) * | 1988-03-29 | 1988-05-05 | Glaxo Group Ltd | Pharmaceutical combinations |
-
1995
- 1995-05-19 EP EP95920275A patent/EP0756489B1/en not_active Expired - Lifetime
- 1995-05-19 ES ES95920275T patent/ES2137516T3/es not_active Expired - Lifetime
- 1995-05-19 WO PCT/KR1995/000059 patent/WO1995032726A1/en active IP Right Grant
- 1995-05-19 DK DK95920275T patent/DK0756489T3/da active
- 1995-05-19 JP JP8500680A patent/JP2936209B2/ja not_active Expired - Lifetime
- 1995-05-19 RU RU96120199A patent/RU2119351C1/ru not_active IP Right Cessation
- 1995-05-19 CN CNB951933647A patent/CN1148224C/zh not_active Expired - Fee Related
- 1995-05-19 AU AU25772/95A patent/AU2577295A/en not_active Abandoned
- 1995-05-19 AT AT95920275T patent/ATE183398T1/de not_active IP Right Cessation
- 1995-05-19 DE DE69511539T patent/DE69511539T2/de not_active Expired - Fee Related
- 1995-05-19 US US08/732,377 patent/US5739105A/en not_active Expired - Fee Related
- 1995-05-30 KR KR1019950013737A patent/KR0163212B1/ko not_active IP Right Cessation
-
1999
- 1999-10-20 GR GR990402665T patent/GR3031568T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE183398T1 (de) | 1999-09-15 |
RU2119351C1 (ru) | 1998-09-27 |
KR960000247A (ko) | 1996-01-25 |
EP0756489B1 (en) | 1999-08-18 |
CN1148224C (zh) | 2004-05-05 |
GR3031568T3 (en) | 2000-01-31 |
WO1995032726A1 (en) | 1995-12-07 |
EP0756489A1 (en) | 1997-02-05 |
JP2936209B2 (ja) | 1999-08-23 |
CN1149834A (zh) | 1997-05-14 |
DK0756489T3 (da) | 1999-12-06 |
US5739105A (en) | 1998-04-14 |
AU2577295A (en) | 1995-12-21 |
KR0163212B1 (ko) | 1998-12-01 |
JPH09510733A (ja) | 1997-10-28 |
DE69511539T2 (de) | 2000-03-30 |
DE69511539D1 (de) | 1999-09-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2137516T3 (es) | Composicion a base de ciclosporina y su procedimiento de fabricacion. | |
RS49611B (sr) | Ziprasidon formulacije | |
WO2001045647A3 (de) | Tablettierung verdickender systeme | |
BG106030A (en) | Pharmaceutical composition | |
DK0695171T3 (da) | Lyosfærer indeholdende gonadotropin | |
DK1091975T3 (da) | Ny cyclosporin med forbedret aktivitetsprofil | |
SE9604793D0 (sv) | New polymorphs | |
DK0775018T4 (da) | Fremgangsmåde til fremstilling af katalysatorer af cobalt på aluminiumoxid | |
TR200001012T2 (tr) | Yeni ariloksi-alkil-dialkilaminler. | |
ATE204297T1 (de) | Peptidanaloge des lh-rh, ihre verwendungen und die sie enthaltenden pharmazeutischen zusammensetzungen | |
AU5186799A (en) | Peptides of il-2 and derivatives thereof and their use as therapeutic agents | |
BG103714A (en) | Pararacetamol-containing tablet | |
DK1131057T3 (da) | Polstrende voksperler til fremstilling af faste, formede genstande | |
HK1043809A1 (en) | Pharmaceutical composition for treating papillomavirus tumours and infection. | |
CA2185541A1 (en) | Cytotoxic t-cell epitopes | |
DE69513157D1 (de) | Heterofunktionelle mucoadhäsive galenische zusammensetzung | |
ZA961364B (en) | 1-Aryl-2-acylamino-ethane compounds | |
WO2001078682A3 (en) | Sustained release drug compositions | |
CA2174707A1 (en) | Chromone derivatives as nk1 and substance p antagonists | |
FR2693746B1 (fr) | Compositions a base de cire et contenant des agents tensio-actifs amphoteres, leur preparation et leur utilisation comme agents de finissage. | |
BR0207066A (pt) | Derivados do 2h-1-benzopirano - processos para sua preparação e composições farmacêuticas a partir deles | |
BR0012751A (pt) | Benzofuranos serotonérgicos | |
MX9604762A (es) | Nuevas sulfonamidas y procedimiento para su preparacion. | |
HRP20000400B1 (en) | Transmucosal formulations of levosimendal | |
ATE251457T1 (de) | Substituierte 1,2,3,4-tetrahydro-2- dibenzofuranamine und 2- aminocyclohepta(b)benzofurane |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 756489 Country of ref document: ES |