DE69513157D1 - Heterofunktionelle mucoadhäsive galenische zusammensetzung - Google Patents

Heterofunktionelle mucoadhäsive galenische zusammensetzung

Info

Publication number
DE69513157D1
DE69513157D1 DE69513157T DE69513157T DE69513157D1 DE 69513157 D1 DE69513157 D1 DE 69513157D1 DE 69513157 T DE69513157 T DE 69513157T DE 69513157 T DE69513157 T DE 69513157T DE 69513157 D1 DE69513157 D1 DE 69513157D1
Authority
DE
Germany
Prior art keywords
pct
layer
mucoad
adhesive
active principle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69513157T
Other languages
English (en)
Inventor
Norbert Emile Bromet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotec Centre SA
Original Assignee
Biotec Centre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotec Centre SA filed Critical Biotec Centre SA
Application granted granted Critical
Publication of DE69513157D1 publication Critical patent/DE69513157D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Materials For Medical Uses (AREA)
DE69513157T 1994-04-01 1995-03-31 Heterofunktionelle mucoadhäsive galenische zusammensetzung Expired - Lifetime DE69513157D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9403895A FR2718020B1 (fr) 1994-04-01 1994-04-01 Composition galénique mucoadhésive hétérofonctionnelle.
PCT/FR1995/000417 WO1995026713A1 (fr) 1994-04-01 1995-03-31 Composition galenique mucoadhesive heterofonctionnelle

Publications (1)

Publication Number Publication Date
DE69513157D1 true DE69513157D1 (de) 1999-12-09

Family

ID=9461682

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69513157T Expired - Lifetime DE69513157D1 (de) 1994-04-01 1995-03-31 Heterofunktionelle mucoadhäsive galenische zusammensetzung

Country Status (8)

Country Link
US (1) US5879710A (de)
EP (1) EP0754033B1 (de)
JP (1) JP4083215B2 (de)
AT (1) ATE186210T1 (de)
CA (1) CA2186863A1 (de)
DE (1) DE69513157D1 (de)
FR (1) FR2718020B1 (de)
WO (1) WO1995026713A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1231900A1 (de) * 1999-11-23 2002-08-21 The Robert Gordon University Zweischichttabletten zur applikation in der mundhöhle enthaltend nicotin
US6458384B2 (en) 2000-02-23 2002-10-01 Impetus Ag Pharmaceutical with predetermined activity profile
IT1318524B1 (it) * 2000-05-17 2003-08-27 Ambros Pharma S R L Composizioni a rilascio controllato contenenti un principio attivo,preferibilmente melatonina, e processo di preparazione delle stesse.
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
US20030194420A1 (en) * 2002-04-11 2003-10-16 Richard Holl Process for loading a drug delivery device
US20050053558A1 (en) * 2003-03-18 2005-03-10 Arthur Zuckerman Sleep inducing toothpaste made with natural herbs and a natural hormone
US8679484B2 (en) 2005-03-02 2014-03-25 Polyrizon Ltd. Method for removal of toxins from mucosal membranes
CN102186461A (zh) * 2008-10-14 2011-09-14 麦克内尔股份公司 多部分口腔内剂型及其用途
US20100124560A1 (en) * 2008-11-14 2010-05-20 Mcneil Ab Multi portion intra-oral dosage form and use thereof
EP2233134A1 (de) 2009-03-27 2010-09-29 McNeil AB Mehrteilige intraorale Darreichungsform mit organoleptischen Eigenschaften
US20100247586A1 (en) * 2009-03-27 2010-09-30 Andreas Hugerth Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties
JP2012527406A (ja) * 2009-05-20 2012-11-08 リングアル コンセグナ ピーティーワイ エルティーディー 口腔内および／または舌下治療用製剤
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
WO2012103411A2 (en) 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
ITMI20110332A1 (it) * 2011-03-03 2012-09-04 Ambros Pharma S R L Formulazioni contenenti melatonina a rilascio pulsatile o sequenziale e procedimento per la loro preparazione
EP2570126B1 (de) 2011-09-16 2014-03-26 Darius Rassoulian Verwendung von Melatonin zur Behandlung akuter Alkoholvergiftung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4470846A (en) * 1981-05-19 1984-09-11 Alcan International Limited Removal of alkali metals and alkaline earth metals from molten aluminum
DE3580384D1 (de) * 1984-04-09 1990-12-13 Toyo Boseki Praeparat mit verzoegerter freigabe zum aufbringen auf die schleimhaeute der mundhoehle.
NL8500724A (nl) * 1985-03-13 1986-10-01 Univ Groningen Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
US4755386A (en) * 1986-01-22 1988-07-05 Schering Corporation Buccal formulation
ES2084709T3 (es) * 1989-11-03 1996-05-16 Riker Laboratories Inc Composicion bioadhesiva y parche.
DE122007000073I1 (de) * 1991-05-09 2008-01-31 Neurim Pharma 1991 Melatonin enthaltene Arzneimittel

Also Published As

Publication number Publication date
EP0754033B1 (de) 1999-11-03
FR2718020A1 (fr) 1995-10-06
US5879710A (en) 1999-03-09
EP0754033A1 (de) 1997-01-22
CA2186863A1 (fr) 1995-10-12
FR2718020B1 (fr) 1996-05-31
JP4083215B2 (ja) 2008-04-30
JPH09510986A (ja) 1997-11-04
WO1995026713A1 (fr) 1995-10-12
ATE186210T1 (de) 1999-11-15

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Legal Events

Date Code Title Description
8332 No legal effect for de