ATE183398T1 - Eine cyclosporin enthaltende zubereitung und ein verfahren für ihre herstellung - Google Patents

Eine cyclosporin enthaltende zubereitung und ein verfahren für ihre herstellung

Info

Publication number
ATE183398T1
ATE183398T1 AT95920275T AT95920275T ATE183398T1 AT E183398 T1 ATE183398 T1 AT E183398T1 AT 95920275 T AT95920275 T AT 95920275T AT 95920275 T AT95920275 T AT 95920275T AT E183398 T1 ATE183398 T1 AT E183398T1
Authority
AT
Austria
Prior art keywords
pct
production
preparation containing
containing cyclosporin
sec
Prior art date
Application number
AT95920275T
Other languages
English (en)
Inventor
Hyun Soo Kim
Jae Yoon Choi
Hye Weon Lee
Young Keun Park
Sung Wook Choi
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Application granted granted Critical
Publication of ATE183398T1 publication Critical patent/ATE183398T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
AT95920275T 1994-06-01 1995-05-19 Eine cyclosporin enthaltende zubereitung und ein verfahren für ihre herstellung ATE183398T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR19940012288 1994-06-01

Publications (1)

Publication Number Publication Date
ATE183398T1 true ATE183398T1 (de) 1999-09-15

Family

ID=19384450

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95920275T ATE183398T1 (de) 1994-06-01 1995-05-19 Eine cyclosporin enthaltende zubereitung und ein verfahren für ihre herstellung

Country Status (13)

Country Link
US (1) US5739105A (de)
EP (1) EP0756489B1 (de)
JP (1) JP2936209B2 (de)
KR (1) KR0163212B1 (de)
CN (1) CN1148224C (de)
AT (1) ATE183398T1 (de)
AU (1) AU2577295A (de)
DE (1) DE69511539T2 (de)
DK (1) DK0756489T3 (de)
ES (1) ES2137516T3 (de)
GR (1) GR3031568T3 (de)
RU (1) RU2119351C1 (de)
WO (1) WO1995032726A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618952D0 (en) * 1996-09-11 1996-10-23 Sandoz Ltd Process
KR100241652B1 (ko) * 1997-07-07 2000-03-02 김충섭 이푸리플라본의 경구 투여용 제제의 제조 방법
AU748334B2 (en) 1997-10-16 2002-05-30 Board Of Regents, The University Of Texas System Models and treatments for cardiac hypertrophy in relation with NF-AT3 function
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
DE19859910C2 (de) * 1998-12-23 2001-03-22 Ratiopharm Gmbh Orales Arzneimittel
WO2000040219A1 (en) 1998-12-30 2000-07-13 Dexcel Ltd. Dispersible concentrate for the delivery of cyclosporin
EP1058539A1 (de) * 1999-01-06 2000-12-13 Korea Research Institute Of Chemical Technology Methode zur herstellung eines pharmazeutisch aktiven bestandteils beinhaltend einen wasserunlöslichen wirkstoff sowie eine pharmazeutische zusammensetzung zur oralen verabreichung die diesen bestandteil enthält
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
ATE250924T1 (de) * 2000-04-07 2003-10-15 Medidom Lab Cyklosporin, hyaluronsäure und polysorbate enthaltenes augenarzneimittel
GB0008785D0 (en) * 2000-04-10 2000-05-31 Novartis Ag Organic compounds
RU2207870C2 (ru) * 2000-11-10 2003-07-10 Панацея Биотек Лимитед Фармацевтическая композиция, включающая циклоспорин в качестве активного ингредиента
PT1435910E (pt) * 2001-10-19 2009-09-07 Isotechnika Inc Novos pré-concentrados de microemulsão de análogos da ciclosporina
US6979672B2 (en) * 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
SI1802650T1 (sl) * 2004-10-01 2012-03-30 Scynexis Inc Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c
ES2314354T3 (es) * 2004-11-09 2009-03-16 Novagali Pharma S.A. Emulsion de tipo aceite en agua con baja concentracion de agente cationico y potencial zeta positivo.
US7151085B2 (en) * 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
CA2595895C (en) 2005-02-02 2016-06-14 Ossur Hf Sensing systems and methods for monitoring gait dynamics
GB0921528D0 (en) 2009-12-09 2010-01-27 Mast Carbon Internat Ltd Carbon and its use in blood cleansing applications
JP6200698B2 (ja) * 2013-06-18 2017-09-20 ニュートリー株式会社 嚥下造影検査食
US20230301910A1 (en) * 2020-11-09 2023-09-28 Scai Therapeutics Co., Ltd. Solid material and dispersion composition containing same
EP4241761A4 (de) * 2020-11-09 2024-09-25 Scai Therapeutics Co., Ltd. Festes cyclosporin a und dispersionszusammensetzung damit

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI65914C (fi) * 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
GB8903804D0 (en) * 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
JP2577049B2 (ja) * 1987-06-04 1997-01-29 三共株式会社 シクロスポリン製剤
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
GB8807505D0 (en) * 1988-03-29 1988-05-05 Glaxo Group Ltd Pharmaceutical combinations
CZ278863B6 (en) * 1992-09-07 1994-07-13 Galena Medicinal preparations with n-methylated cyclic undecapeptides

Also Published As

Publication number Publication date
JP2936209B2 (ja) 1999-08-23
EP0756489B1 (de) 1999-08-18
ES2137516T3 (es) 1999-12-16
US5739105A (en) 1998-04-14
CN1148224C (zh) 2004-05-05
JPH09510733A (ja) 1997-10-28
DE69511539T2 (de) 2000-03-30
KR960000247A (ko) 1996-01-25
AU2577295A (en) 1995-12-21
KR0163212B1 (ko) 1998-12-01
DE69511539D1 (de) 1999-09-23
RU2119351C1 (ru) 1998-09-27
WO1995032726A1 (en) 1995-12-07
GR3031568T3 (en) 2000-01-31
DK0756489T3 (da) 1999-12-06
CN1149834A (zh) 1997-05-14
EP0756489A1 (de) 1997-02-05

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