ES2137511T3 - Compuestos que contienen un aceptor de michael, especialmente derivados de maleimida o acido maleico, directamente o indirectamente conectado a un cromoforo, y su uso en composiciones de proteccion solar de larga duracion. - Google Patents
Compuestos que contienen un aceptor de michael, especialmente derivados de maleimida o acido maleico, directamente o indirectamente conectado a un cromoforo, y su uso en composiciones de proteccion solar de larga duracion.Info
- Publication number
- ES2137511T3 ES2137511T3 ES95918063T ES95918063T ES2137511T3 ES 2137511 T3 ES2137511 T3 ES 2137511T3 ES 95918063 T ES95918063 T ES 95918063T ES 95918063 T ES95918063 T ES 95918063T ES 2137511 T3 ES2137511 T3 ES 2137511T3
- Authority
- ES
- Spain
- Prior art keywords
- michael acceptor
- chromophorus
- maleimide
- directly
- long
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
- C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
- C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/94—Involves covalent bonding to the substrate
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Coloring (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A COMPUESTOS QUE SON UTILES COMO PROTECTORES SOLARES. LOS COMPUESTOS PERSISTEN EN LA PIEL DURANTE MUCHO MAS TIEMPO QUE LOS PROTECTORES SOLARES CONVENCIONALES PORQUE COMPRENDEN UN ACEPTOR DE MICHAEL LIGADO DIRECTA O INDIRECTAMENTE A UN CROMOFORO. EL ACEPTOR DE MICHAEL ES CAPAZ DE SUFRIR UNA REACCION A LA ADICCION CONJUGADA CON GRUPOS TID PRESENTES EN LOS RESIDUOS DE CISTEINA DE QUERATINA Y DE ESTA MANERA EL COMPUESTO ESTA QUIMICAMENTE LIGADO A LA PIEL Y NO SERA ELIMINADO POR LA INMERSION EN EL AGUA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9408994A GB9408994D0 (en) | 1994-05-06 | 1994-05-06 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2137511T3 true ES2137511T3 (es) | 1999-12-16 |
Family
ID=10754654
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95918063T Expired - Lifetime ES2137511T3 (es) | 1994-05-06 | 1995-05-09 | Compuestos que contienen un aceptor de michael, especialmente derivados de maleimida o acido maleico, directamente o indirectamente conectado a un cromoforo, y su uso en composiciones de proteccion solar de larga duracion. |
Country Status (20)
Country | Link |
---|---|
US (1) | US5877204A (es) |
EP (1) | EP0758314B1 (es) |
JP (1) | JPH10502338A (es) |
CN (1) | CN1149866A (es) |
AT (1) | ATE184592T1 (es) |
AU (1) | AU698618B2 (es) |
BR (1) | BR9507624A (es) |
CA (1) | CA2189337A1 (es) |
DE (1) | DE69512229T2 (es) |
DK (1) | DK0758314T3 (es) |
ES (1) | ES2137511T3 (es) |
FI (1) | FI964444A (es) |
GB (1) | GB9408994D0 (es) |
GR (1) | GR3032104T3 (es) |
IL (1) | IL113639A0 (es) |
NO (1) | NO310718B1 (es) |
NZ (1) | NZ285132A (es) |
RU (1) | RU2162838C2 (es) |
WO (1) | WO1995030646A1 (es) |
ZA (1) | ZA953655B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE293951T1 (de) | 1997-12-08 | 2005-05-15 | Univ Arizona State | Langwirkende, chemisch widerstandfähige haut- weichmachende, -feuchthaltemittel und -verstärker |
US7601691B2 (en) * | 1999-05-17 | 2009-10-13 | Conjuchem Biotechnologies Inc. | Anti-obesity agents |
CN1538834A (zh) | 2001-03-07 | 2004-10-20 | 包括功能性烷基化化妆品键合剂的局部组合物 | |
CA2448231A1 (en) | 2001-03-07 | 2002-10-03 | The Procter & Gamble Company | Cosmetic topical composition comprising a functional aromatic derivative bonding agent |
JP2004536039A (ja) | 2001-03-07 | 2004-12-02 | ザ プロクター アンド ギャンブル カンパニー | 環式イミドカーボネートに基づく化粧品結合剤を含む局所用組成物 |
CN1535136A (zh) | 2001-03-07 | 2004-10-06 | 宝洁公司 | 包括官能化的基于酸酐的化妆品键合剂的局部组合物 |
MXPA03008100A (es) | 2001-03-07 | 2003-12-12 | Procter & Gamble | Composicion topica que comprende un agente cosmetico enlazante con base de compuesto ciclico de tres miembros. |
CA2448227A1 (en) | 2001-03-07 | 2002-09-19 | The Procter & Gamble Company | Topical composition comprising a diazonium salt-based cosmetic bonding agent |
MXPA03008104A (es) | 2001-03-07 | 2003-12-12 | Procter & Gamble | Composicion topica que contiene un agente cosmetico enlazante con funcion acilante. |
MXPA03008111A (es) | 2001-03-07 | 2003-12-12 | Procter & Gamble | Composicion topica que comprende un agente cosmetico enlazante basado en aldehido o cetona. |
MXPA03008099A (es) | 2001-03-07 | 2003-12-12 | Procter & Gamble | Composicion topica que comprende un agente enlazante cosmetico de dieno constituido por un 1,2-heteroatomo. |
CN1536983A (zh) | 2001-05-30 | 2004-10-13 | 宝洁公司 | 包括取代的化妆品键合剂的局部组合物 |
US6607737B2 (en) | 2001-05-30 | 2003-08-19 | The Procter & Gamble Company | Topical composition comprising an activated, trans-structured cosmetic bonding agent |
WO2004019858A2 (en) * | 2002-08-30 | 2004-03-11 | Isp Investments Inc. | Natural feel polymers |
DE10358432B4 (de) * | 2003-12-13 | 2005-12-01 | Ziegler Mechanische Werkstatt, Metallgewebe Und Arbeitsschutz Gmbh | Federspanner |
US8591885B2 (en) * | 2004-04-30 | 2013-11-26 | Allergan, Inc. | Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems |
US7022861B1 (en) | 2004-06-10 | 2006-04-04 | Sandia National Laboratories | Thermally cleavable surfactants |
DE102004039281A1 (de) | 2004-08-13 | 2006-02-23 | Merck Patent Gmbh | UV Filter |
DE102005047647A1 (de) | 2005-10-05 | 2007-04-12 | Merck Patent Gmbh | a,a'-Dihydroxyketonderivate und deren Verwendung als UV-Filter |
DE102005058542A1 (de) * | 2005-12-08 | 2007-06-14 | Merck Patent Gmbh | Erythruloseester als UV Filter |
US20090099074A1 (en) * | 2007-01-10 | 2009-04-16 | Conjuchem Biotechnologies Inc. | Modulating food intake |
JP5119767B2 (ja) * | 2007-07-05 | 2013-01-16 | コニカミノルタアドバンストレイヤー株式会社 | 光学フィルム、偏光板、その製造方法及び液晶表示装置 |
US20100158829A1 (en) * | 2008-12-24 | 2010-06-24 | Conopco, Inc., D/B/A Unilever | Method and Composition for Color Modulation |
US10912761B2 (en) | 2012-11-30 | 2021-02-09 | The University Of Chicago | Methods and compositions involving RAD51 inhibitors |
WO2020082296A1 (en) * | 2018-10-25 | 2020-04-30 | Yimin Sun | A sunscreen formulation |
TWI692467B (zh) * | 2018-12-28 | 2020-05-01 | 健裕生技股份有限公司 | 促進心肌再生之化合物、其製法、醫藥品及其用途 |
JP6768868B2 (ja) * | 2019-03-29 | 2020-10-14 | 健裕生技股▲分▼有限公司 | 心筋再生を促進させるための化合物、その調製方法及びこれらの使用 |
US11124472B2 (en) | 2019-04-08 | 2021-09-21 | Genhealth Pharma Co., Ltd. | Myocardial regeneration promoting compounds, preparation method thereof, and pharmaceutical composition |
EP4077279A1 (en) * | 2019-12-19 | 2022-10-26 | Skinosive | Adhesive photoprotective compounds and uses thereof |
JP2020164528A (ja) * | 2020-04-28 | 2020-10-08 | 健裕生技股▲分▼有限公司 | 心筋再生を促進させるための化合物、その調製方法、医薬組成物及びこれらの使用 |
WO2023247598A1 (en) * | 2022-06-22 | 2023-12-28 | Skinosive | Multi-photoprotective compounds and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3322817A (en) * | 1963-03-15 | 1967-05-30 | Nat Starch Chem Corp | Aromatic and aliphatic esters of hydroxy benzophenone derivatives |
US3489739A (en) * | 1966-09-08 | 1970-01-13 | Rohm & Haas | Novel carboalkoxyphenyl acrylates and polymers thereof |
FR1568382A (es) * | 1968-04-09 | 1969-05-23 | ||
US3751449A (en) * | 1969-06-26 | 1973-08-07 | Minnesota Mining & Mfg | Cycloaliphatic and phenylalkyl acrylates and vinyl esters |
FR2278331A1 (fr) * | 1974-01-24 | 1976-02-13 | Roussel Uclaf | Nouveaux acides carboxyliques et leurs derives, leur application comme medicaments et leur procede de preparation |
US4999186A (en) * | 1986-06-27 | 1991-03-12 | The Procter & Gamble Company | Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn |
JP2883107B2 (ja) * | 1989-07-10 | 1999-04-19 | 塩野義製薬株式会社 | 紫外線吸収皮膚保護剤組成物 |
-
1994
- 1994-05-06 GB GB9408994A patent/GB9408994D0/en active Pending
-
1995
- 1995-05-05 ZA ZA953655A patent/ZA953655B/xx unknown
- 1995-05-07 IL IL11363995A patent/IL113639A0/xx unknown
- 1995-05-09 NZ NZ285132A patent/NZ285132A/xx unknown
- 1995-05-09 AT AT95918063T patent/ATE184592T1/de not_active IP Right Cessation
- 1995-05-09 DK DK95918063T patent/DK0758314T3/da active
- 1995-05-09 CA CA002189337A patent/CA2189337A1/en not_active Abandoned
- 1995-05-09 AU AU24136/95A patent/AU698618B2/en not_active Ceased
- 1995-05-09 DE DE69512229T patent/DE69512229T2/de not_active Expired - Fee Related
- 1995-05-09 BR BR9507624A patent/BR9507624A/pt not_active Application Discontinuation
- 1995-05-09 ES ES95918063T patent/ES2137511T3/es not_active Expired - Lifetime
- 1995-05-09 EP EP95918063A patent/EP0758314B1/en not_active Expired - Lifetime
- 1995-05-09 JP JP7528784A patent/JPH10502338A/ja active Pending
- 1995-05-09 CN CN95193471A patent/CN1149866A/zh active Pending
- 1995-05-09 WO PCT/GB1995/001035 patent/WO1995030646A1/en active IP Right Grant
- 1995-05-09 RU RU96123294/04A patent/RU2162838C2/ru not_active IP Right Cessation
-
1996
- 1996-11-05 FI FI964444A patent/FI964444A/fi unknown
- 1996-11-05 NO NO19964675A patent/NO310718B1/no not_active IP Right Cessation
- 1996-11-05 US US08/755,757 patent/US5877204A/en not_active Expired - Fee Related
-
1999
- 1999-12-10 GR GR990403194T patent/GR3032104T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO1995030646A1 (en) | 1995-11-16 |
FI964444A0 (fi) | 1996-11-05 |
DK0758314T3 (da) | 2000-03-27 |
BR9507624A (pt) | 1997-10-07 |
DE69512229D1 (de) | 1999-10-21 |
GB9408994D0 (en) | 1994-06-22 |
EP0758314A1 (en) | 1997-02-19 |
NZ285132A (en) | 1999-06-29 |
JPH10502338A (ja) | 1998-03-03 |
GR3032104T3 (en) | 2000-03-31 |
NO310718B1 (no) | 2001-08-20 |
RU2162838C2 (ru) | 2001-02-10 |
AU2413695A (en) | 1995-11-29 |
US5877204A (en) | 1999-03-02 |
CA2189337A1 (en) | 1995-11-16 |
IL113639A0 (en) | 1995-08-31 |
ATE184592T1 (de) | 1999-10-15 |
EP0758314B1 (en) | 1999-09-15 |
CN1149866A (zh) | 1997-05-14 |
AU698618B2 (en) | 1998-11-05 |
NO964675L (no) | 1997-01-06 |
ZA953655B (en) | 1996-11-05 |
FI964444A (fi) | 1997-01-03 |
NO964675D0 (no) | 1996-11-05 |
DE69512229T2 (de) | 2000-04-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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