ES2125864T3 - Vectores bacterianos. - Google Patents

Vectores bacterianos.

Info

Publication number
ES2125864T3
ES2125864T3 ES91810167T ES91810167T ES2125864T3 ES 2125864 T3 ES2125864 T3 ES 2125864T3 ES 91810167 T ES91810167 T ES 91810167T ES 91810167 T ES91810167 T ES 91810167T ES 2125864 T3 ES2125864 T3 ES 2125864T3
Authority
ES
Spain
Prior art keywords
new
spec
lactococcus
production
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91810167T
Other languages
English (en)
Spanish (es)
Inventor
Bruno Dr Suri
Albert Dr Schmitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Nestle SA
Original Assignee
Societe des Produits Nestle SA
Nestle SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe des Produits Nestle SA, Nestle SA filed Critical Societe des Produits Nestle SA
Application granted granted Critical
Publication of ES2125864T3 publication Critical patent/ES2125864T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
ES91810167T 1990-03-22 1991-03-13 Vectores bacterianos. Expired - Lifetime ES2125864T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909006400A GB9006400D0 (en) 1990-03-22 1990-03-22 Bacterial vectors

Publications (1)

Publication Number Publication Date
ES2125864T3 true ES2125864T3 (es) 1999-03-16

Family

ID=10673033

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91810167T Expired - Lifetime ES2125864T3 (es) 1990-03-22 1991-03-13 Vectores bacterianos.

Country Status (22)

Country Link
US (1) US5559007A (cg-RX-API-DMAC10.html)
EP (1) EP0449770B1 (cg-RX-API-DMAC10.html)
JP (1) JPH04211384A (cg-RX-API-DMAC10.html)
KR (1) KR910016930A (cg-RX-API-DMAC10.html)
AR (1) AR245504A1 (cg-RX-API-DMAC10.html)
AT (1) ATE174055T1 (cg-RX-API-DMAC10.html)
AU (1) AU643511B2 (cg-RX-API-DMAC10.html)
BR (1) BR9101137A (cg-RX-API-DMAC10.html)
CA (1) CA2038706A1 (cg-RX-API-DMAC10.html)
DE (1) DE69130544T2 (cg-RX-API-DMAC10.html)
DK (1) DK0449770T3 (cg-RX-API-DMAC10.html)
ES (1) ES2125864T3 (cg-RX-API-DMAC10.html)
FI (1) FI911367A7 (cg-RX-API-DMAC10.html)
GB (1) GB9006400D0 (cg-RX-API-DMAC10.html)
HU (1) HUT57263A (cg-RX-API-DMAC10.html)
IE (1) IE910948A1 (cg-RX-API-DMAC10.html)
MX (1) MX25027A (cg-RX-API-DMAC10.html)
NO (1) NO911138L (cg-RX-API-DMAC10.html)
NZ (1) NZ237506A (cg-RX-API-DMAC10.html)
PT (1) PT97081B (cg-RX-API-DMAC10.html)
TW (1) TW213488B (cg-RX-API-DMAC10.html)
ZA (1) ZA912114B (cg-RX-API-DMAC10.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286361A (en) * 1992-10-19 1994-02-15 Regents Of The University Of California Magnetically attached sputter targets
AU2149495A (en) * 1995-04-11 1996-10-30 Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno Method for the construction of vectors for lactic acid bacte ria like lactobacillus such that the bacteria can efficientl y express, secrete and display proteins at the surface
GB9521568D0 (en) * 1995-10-20 1995-12-20 Lynxvale Ltd Delivery of biologically active polypeptides
PT925364E (pt) * 1996-09-06 2003-03-31 Bioteknologisk Inst Sistema de expressao regulavel de bacterias de acido lactico
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
WO2004001020A2 (en) 2002-06-19 2003-12-31 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Methods and means to promote gut absorption
CA2506031A1 (en) * 2002-11-15 2004-06-03 Vib Vzw Self-containing lactobacillus strain comprising a thya mutation and therapeutic applications thereof
EP3097924B1 (en) 2005-11-29 2020-01-08 Intrexon Actobiotics NV Induction of mucosal tolerance to gliadin
CA2675115C (en) 2007-01-12 2014-12-09 Actogenix N.V. Lactococcus promoters and uses thereof
CN103933563B (zh) 2007-01-25 2016-09-28 英特瑞克斯顿阿克图比奥帝克斯有限公司 使用遗传修饰的乳杆菌通过抗原的粘膜递送治疗免疫疾病
JP5126879B2 (ja) * 2007-07-13 2013-01-23 独立行政法人海洋研究開発機構 新規ｄｎａ断片およびそれを含む組換えベクター、それらによって形質転換された形質転換体、ならびにそれらの利用
DK3181682T3 (da) 2008-09-29 2021-07-05 Intrexon Actobiotics Nv Reduceret kolonisering af mikrober på slimhinden
US9574169B2 (en) 2009-04-30 2017-02-21 Intrexon Actobiotics Nv Cryoprotectants for freeze drying of lactic acid bacteria
EP2275527A1 (en) 2009-07-17 2011-01-19 ActoGeniX NV Animal component-free culture medium for bacterial fermentation
US20120183503A1 (en) 2009-09-29 2012-07-19 Actogenix N.V. Lactobacillus and streptococcus promoters and uses thereof
US20130164380A1 (en) 2010-06-17 2013-06-27 Actogenix Nv Compositions and methods for treating inflammatory conditions
JP6175428B2 (ja) 2011-06-01 2017-08-02 イントレクソン・アクトバイオテイクス・エヌブイＩｎｔｒｅｘｏｎ Ａｃｔｏｂｉｏｔｉｃｓ ＮＶ 細菌のポリシストロン性発現系
KR102028771B1 (ko) 2011-09-23 2019-10-04 인트랙슨 액토바이오틱스 엔.브이. 변형된 그람 양성 박테리아 및 그 사용 방법
JP6117212B2 (ja) 2011-09-23 2017-04-19 イントレクソン・アクトバイオテイクス・エヌブイＩｎｔｒｅｘｏｎ Ａｃｔｏｂｉｏｔｉｃｓ ＮＶ 改変されたグラム陽性菌及びその使用
EP3919065B9 (en) 2016-01-14 2024-01-24 Intrexon Actobiotics NV Compositions and methods for the treatment of type 1 diabetes
CN110637089B (zh) * 2017-03-22 2024-08-02 新加坡科技研究局 蛋白质表达构建体及其方法
CN116144690A (zh) * 2022-08-23 2023-05-23 江西省科学院微生物研究所(江西省流域生态研究所) 一种大肠杆菌与乳酸菌的穿梭载体pDXA及构建方法与应用
WO2025233675A1 (en) 2024-05-10 2025-11-13 Institut Pasteur Use of talosaminidase to regulate populations of archaeal methanogens in industrial, agricultural and medical settings
WO2025253171A1 (en) 2024-06-04 2025-12-11 Institut Pasteur Characterization of viruses associated with the zoonotic fish-borne oncogenic liver flukes and applications thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8400687A (nl) 1984-03-02 1985-10-01 Unilever Nv Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit.
EP0168342B1 (de) 1984-06-14 1991-07-03 Ciba-Geigy Ag Verfahren zur Herstellung von Thrombin-Inhibitoren
NL8503316A (nl) * 1985-11-29 1987-06-16 Stichting Nl I Zuivelonderzoek Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen.
EP0316677A3 (en) 1987-11-13 1990-04-25 Miles Inc. Method for cloning in lactic acid bacteria
NL9000753A (nl) * 1990-03-30 1991-10-16 Nl Zuivelonderzoek Inst Dna-fragment, ten minste coderend voor een deel van het extracellulaire eiwit met een schijnbaar molecuulgewicht van 60 kda van lactococcus lactis stammen zoals de lactococcus lactis ssp. lactis stam mg1363, combinaties hiervan met voor homologe of heterologe eiwitten coderende dna-sequenties alsmede de hiermee verkregen homologe en heterologe eiwitten.

Also Published As

Publication number Publication date
KR910016930A (ko) 1991-11-05
DE69130544D1 (de) 1999-01-14
FI911367A0 (fi) 1991-03-20
DK0449770T3 (da) 1999-06-23
EP0449770A2 (en) 1991-10-02
MX25027A (es) 1993-12-01
PT97081A (pt) 1991-11-29
ATE174055T1 (de) 1998-12-15
DE69130544T2 (de) 1999-04-29
IE910948A1 (en) 1991-09-25
BR9101137A (pt) 1991-11-05
NO911138D0 (no) 1991-03-21
ZA912114B (en) 1992-01-29
AU7355891A (en) 1991-10-03
CA2038706A1 (en) 1991-09-23
TW213488B (cg-RX-API-DMAC10.html) 1993-09-21
HUT57263A (en) 1991-11-28
AR245504A1 (es) 1994-01-31
JPH04211384A (ja) 1992-08-03
AU643511B2 (en) 1993-11-18
EP0449770A3 (en) 1992-07-01
FI911367L (fi) 1991-09-23
EP0449770B1 (en) 1998-12-02
PT97081B (pt) 1998-07-31
US5559007A (en) 1996-09-24
GB9006400D0 (en) 1990-05-23
FI911367A7 (fi) 1991-09-23
NZ237506A (en) 1992-12-23
NO911138L (no) 1991-09-23
HU910958D0 (en) 1991-10-28

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