DK3181682T3 - Reduceret kolonisering af mikrober på slimhinden - Google Patents
Reduceret kolonisering af mikrober på slimhinden Download PDFInfo
- Publication number
- DK3181682T3 DK3181682T3 DK17154984.3T DK17154984T DK3181682T3 DK 3181682 T3 DK3181682 T3 DK 3181682T3 DK 17154984 T DK17154984 T DK 17154984T DK 3181682 T3 DK3181682 T3 DK 3181682T3
- Authority
- DK
- Denmark
- Prior art keywords
- muckins
- microbes
- reduced colonization
- colonization
- reduced
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/01—Methyltransferases (2.1.1)
- C12Y201/01045—Thymidylate synthase (2.1.1.45)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08105458 | 2008-09-29 | ||
| EP09736880.7A EP2344626B1 (en) | 2008-09-29 | 2009-09-29 | Reduced colonization of microbes at the mucosa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3181682T3 true DK3181682T3 (da) | 2021-07-05 |
Family
ID=41348919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17154984.3T DK3181682T3 (da) | 2008-09-29 | 2009-09-29 | Reduceret kolonisering af mikrober på slimhinden |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110150850A1 (da) |
| EP (3) | EP2344626B1 (da) |
| JP (1) | JP2012504116A (da) |
| CA (1) | CA2738781C (da) |
| DK (1) | DK3181682T3 (da) |
| WO (1) | WO2010034844A1 (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3192873A1 (en) * | 2009-09-29 | 2017-07-19 | Intrexon Actobiotics NV | Lactobacillus and streptococcus promoters and uses thereof |
| DK2758513T3 (da) | 2011-09-23 | 2018-07-23 | Intrexon Actobiotics Nv | Modifiecerede grampositive bakterier og anvendelser deraf |
| ES2676707T3 (es) | 2011-09-23 | 2018-07-24 | Intrexon Actobiotics Nv | Bacterias gram positivas modificadas y usos de las mismas |
| WO2015022798A1 (ja) * | 2013-08-13 | 2015-02-19 | 学校法人北里研究所 | 新規テルペノイド化合物およびその製造方法 |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| US9889164B2 (en) | 2014-12-05 | 2018-02-13 | Synlogic, Inc. | Bacteria engineered to treat a disease or disorder |
| US20160206666A1 (en) | 2014-12-22 | 2016-07-21 | Synlogic, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier |
| AU2015370982B2 (en) | 2014-12-23 | 2019-03-21 | Ilya Pharma Ab | Methods for wound healing |
| US11883439B2 (en) | 2015-05-13 | 2024-01-30 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
| US11291693B2 (en) | 2015-06-25 | 2022-04-05 | Synlogic Operating Company, Inc. | Bacteria engineered to treat metabolic diseases |
| US11685925B2 (en) | 2015-10-30 | 2023-06-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| PL3377518T3 (pl) | 2015-11-16 | 2022-09-26 | Synlogic Operating Company, Inc. | Bakterie modyfikowane do celów zmniejszenia hiperfenyloalaninemii |
| EP4302824A3 (en) | 2016-04-20 | 2024-03-20 | The Board of Trustees of the Leland Stanford Junior University | Compositions and methods for nucleic acid expression and protein secretion in bacteroides |
| WO2018112194A1 (en) | 2016-12-15 | 2018-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for modulating growth of a genetically modified gut bacterial cell |
| IL271085B1 (en) | 2017-06-21 | 2024-03-01 | Synlogic Operating Co Inc | Bacteria to treat disorders |
| WO2019061263A1 (en) * | 2017-09-29 | 2019-04-04 | Dupont Nutrition Biosciences Aps | NOVEL STRAIN OF LACTOBACILLUS PLANTARUM AND USES THEREOF |
| GB201718133D0 (en) * | 2017-11-02 | 2017-12-20 | Sporegen Ltd | Modified bacterial spores |
| CN112391305B (zh) * | 2019-08-15 | 2023-01-13 | 上海交通大学 | 唾液链球菌f286及其用途 |
| CN110878267B (zh) * | 2019-11-21 | 2023-01-31 | 中国农业科学院兰州兽医研究所 | 一株唾液乳杆菌及其用途 |
| EP4121525A1 (en) | 2020-03-20 | 2023-01-25 | Synlogic Operating Company, Inc. | Microorganisms engineered to reduce hyperphenylalaninemia |
| WO2021195672A1 (en) * | 2020-03-26 | 2021-09-30 | The Regents Of The University Of California | Detection and treatment of intestinal fibrosis |
| KR102231437B1 (ko) * | 2020-09-21 | 2021-03-24 | 주식회사 보삼바이오산업 | 고병원성 조류 인플루엔자 바이러스 감염의 예방 또는 치료용 조성물의 제조방법 및 그를 이용하여 제조한 고병원성 조류 인플루엔자 바이러스 감염의 예방 또는 치료용 조성물 |
| WO2024074540A2 (en) | 2022-10-06 | 2024-04-11 | Danmarks Tekniske Universitet | Biocontainment strategies for in vivo applications of yeasts |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4006521A1 (de) | 1990-03-02 | 1991-09-05 | Bayer Ag | Zuckerhaltige polymere zur umhuellung und einbettung von arzneistoffen |
| GB9006400D0 (en) | 1990-03-22 | 1990-05-23 | Ciba Geigy Ag | Bacterial vectors |
| IT1270123B (it) | 1994-10-05 | 1997-04-28 | Dompe Spa | Composizioni farmaceutiche contenenti microorganismi ingegnerizzati e loro uso per terapia |
| US5607672A (en) | 1995-06-07 | 1997-03-04 | University Of Florida Research Foundation, Inc. | Replacement therapy for dental caries |
| GB9518323D0 (en) * | 1995-09-07 | 1995-11-08 | Steidler Lothar | Materials and methods relating to the attachment and display of substances on cell surfaces |
| GB9521568D0 (en) * | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
| GB9700939D0 (en) | 1997-01-17 | 1997-03-05 | Microbial Technics Limited | Therapy |
| EP1123314B1 (en) | 1998-10-20 | 2004-02-18 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Use of a cytokine-producing lactococcus strain to treat colitis |
| ATE342983T1 (de) * | 1999-07-05 | 2006-11-15 | Vlaams Interuniv Inst Biotech | Bereitstellung von peptiden mit kleeblattstruktur |
| US7780961B2 (en) * | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| CA2446776C (en) * | 2001-05-03 | 2011-07-12 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Self-containing lactococcus strain |
| EP1513545B1 (en) * | 2002-06-19 | 2008-03-19 | Actogenix N.V. | Methods and means to promote gut absorption |
| WO2004046346A2 (en) | 2002-11-15 | 2004-06-03 | Vib Vzw | Self-containing lactobacillus strain |
| JP2007537741A (ja) * | 2004-05-18 | 2007-12-27 | フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー（ヴェーイーベー・ヴェーゼットウェー） | 自己収容性乳酸桿株 |
| US8759088B2 (en) * | 2007-01-12 | 2014-06-24 | Actogenix N.V. | Lactococcus promoters and uses thereof |
-
2009
- 2009-09-29 EP EP09736880.7A patent/EP2344626B1/en active Active
- 2009-09-29 JP JP2011528366A patent/JP2012504116A/ja active Pending
- 2009-09-29 WO PCT/EP2009/062647 patent/WO2010034844A1/en active Application Filing
- 2009-09-29 EP EP21169279.3A patent/EP3933029A3/en not_active Withdrawn
- 2009-09-29 DK DK17154984.3T patent/DK3181682T3/da active
- 2009-09-29 EP EP17154984.3A patent/EP3181682B1/en active Active
- 2009-09-29 CA CA2738781A patent/CA2738781C/en active Active
- 2009-09-29 US US12/737,929 patent/US20110150850A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2738781C (en) | 2020-06-09 |
| US20110150850A1 (en) | 2011-06-23 |
| EP2344626B1 (en) | 2017-03-29 |
| EP3933029A2 (en) | 2022-01-05 |
| JP2012504116A (ja) | 2012-02-16 |
| CA2738781A1 (en) | 2010-04-01 |
| WO2010034844A1 (en) | 2010-04-01 |
| EP3181682A1 (en) | 2017-06-21 |
| EP3181682B1 (en) | 2021-04-21 |
| EP3933029A3 (en) | 2022-03-23 |
| EP2344626A1 (en) | 2011-07-20 |
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