ES2123510T3 - Uso de la 2-fenil-1,2-benciisoselenazol-3(2h)-ona. - Google Patents

Uso de la 2-fenil-1,2-benciisoselenazol-3(2h)-ona.

Info

Publication number
ES2123510T3
ES2123510T3 ES91914052T ES91914052T ES2123510T3 ES 2123510 T3 ES2123510 T3 ES 2123510T3 ES 91914052 T ES91914052 T ES 91914052T ES 91914052 T ES91914052 T ES 91914052T ES 2123510 T3 ES2123510 T3 ES 2123510T3
Authority
ES
Spain
Prior art keywords
phenyl
benzyzoselenazol
benzisoselenazol
ebselen
cisplatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91914052T
Other languages
English (en)
Inventor
Glenn S Baldew
N P E Vermeulen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Rhone Poulenc Rorer GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer GmbH filed Critical Rhone Poulenc Rorer GmbH
Application granted granted Critical
Publication of ES2123510T3 publication Critical patent/ES2123510T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA 2-FENIL-1,2-BENCISOSELENAZOL-3(2H)-ONA (EBSELENO) ES CAPAZ DE REDUCIR LA NEFROTOXICIDAD CISPLATIN-INDUCIDA Y LA NEUROTOXICIDAD DURANTE EL TRATAMIENTO CITOSTATICO.
ES91914052T 1990-08-06 1991-07-31 Uso de la 2-fenil-1,2-benciisoselenazol-3(2h)-ona. Expired - Lifetime ES2123510T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4024885A DE4024885C2 (de) 1990-08-06 1990-08-06 Verwendung von 2-Phenyl-1,2-benzisoselenazol-3(2H)-on

Publications (1)

Publication Number Publication Date
ES2123510T3 true ES2123510T3 (es) 1999-01-16

Family

ID=6411708

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91914052T Expired - Lifetime ES2123510T3 (es) 1990-08-06 1991-07-31 Uso de la 2-fenil-1,2-benciisoselenazol-3(2h)-ona.

Country Status (8)

Country Link
EP (1) EP0542807B1 (es)
JP (1) JP3084062B2 (es)
AT (1) ATE171621T1 (es)
CA (1) CA2088760C (es)
DE (2) DE4024885C2 (es)
DK (1) DK0542807T3 (es)
ES (1) ES2123510T3 (es)
WO (1) WO1992002221A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2553434B2 (ja) * 1992-04-28 1996-11-13 第一製薬株式会社 粒状製剤
ATE190487T1 (de) 1993-10-27 2000-04-15 Daiichi Seiyaku Co Granuläre zubereitung
ES2177849T3 (es) * 1996-08-27 2002-12-16 Nattermann A & Cie Preparado farmaceutico, que contiene 2-fenil-1,2-benzoisoselenazol-3(2h)-ona, para el tratamiento de la enfermedad de alzheimer.
DE19825746A1 (de) 1998-06-09 1999-12-16 Biosyn Arzneimittel Gmbh Kombination von Selen-haltigen Verbindungen mit Zytostatika
CN1166651C (zh) * 2001-06-08 2004-09-15 北京大学药学院 具有抗炎和抗肿瘤作用r-双或糖苯丙异硒唑取代化合物
CN1589149A (zh) * 2001-09-24 2005-03-02 托斯克公司 减低毒性的顺铂制剂及其使用方法
CA2466869C (en) * 2001-11-29 2010-01-19 Sound Pharmaceuticals Incorporated Methods and compositions for ameliorating the undesirable effects of chemotherapy
ES2497716T3 (es) 2002-01-04 2014-09-23 Sound Pharmaceuticals Incorporated Composiciones para utilizar en métodos destinados a tratar la pérdida auditiva
AU2006220626A1 (en) * 2005-03-08 2006-09-14 Sound Pharmaceuticals Incorporated Methods and compositions for treating cancer
GB201102248D0 (en) 2011-02-09 2011-03-23 Isis Innovation Treatment of bipolar disorder

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027073C2 (de) * 1980-07-17 1985-03-07 A. Nattermann & Cie GmbH, 5000 Köln Pharmazeutische Präparate, enthaltend 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
DE3616923A1 (de) * 1986-05-20 1987-11-26 Nattermann A & Cie Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on
DE3638124C2 (de) * 1986-11-08 1996-09-05 Nattermann A & Cie Neue pharmazeutische Verwendung von Ebselen
DE3821392A1 (de) * 1988-06-24 1989-12-28 Nattermann A & Cie Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on (ebselen)

Also Published As

Publication number Publication date
DE4024885C2 (de) 2002-07-18
WO1992002221A1 (en) 1992-02-20
DK0542807T3 (da) 1999-06-21
EP0542807B1 (en) 1998-09-30
EP0542807A1 (en) 1993-05-26
JPH05509309A (ja) 1993-12-22
ATE171621T1 (de) 1998-10-15
DE69130292T2 (de) 1999-04-08
CA2088760A1 (en) 1993-02-01
JP3084062B2 (ja) 2000-09-04
DE69130292D1 (de) 1998-11-05
CA2088760C (en) 2002-05-07
DE4024885A1 (de) 1992-02-13

Similar Documents

Publication Publication Date Title
DE69510940T2 (de) Pyrazolo und pyrrolopyridine
SE9101815L (sv) Behandling av sjukdom foerbunden med hiv-infektioner
DK261490D0 (da) New pharmaceutical compound
ES2123510T3 (es) Uso de la 2-fenil-1,2-benciisoselenazol-3(2h)-ona.
DK278788A (da) Ostomikobling
IT1264965B1 (it) Uso di alfa 1-bloccanti nel trattamento della eiaculazione precoce
DE69114160T2 (de) Herstellungsverfahren eines ausgerichteten und strukturierten Körpers.
ES2128335T3 (es) Derivados de imidazo(1,2-c)quinazolina como antihipertensivos y antidisuricos.
NZ336804A (en) Use of pramipexole in the treatment of restless legs syndrome
DE69015344D1 (de) Phosphatzusammensetzungen, gesinterter Körper davon und Herstellung dieses gesinterten Körpers.
ES2052859T3 (es) Procedimiento para producir soluciones parenterales estables de 2-fenil-1,2-benzo-isoselenazol-3(2h)-ona.
DE59106803D1 (de) Substituierte Pyrido-oxazine.
DE68918562T2 (de) Menschliche myeloperoxidase und therapeutische verwendung.
EP0270841A3 (de) 2-Methyl-3-(p-methyl-phenyl)-propionitril, dessen Herstellung und Verwendung als Riechstoff
GR3001850T3 (en) Expellants of phytopathogenic microbes
BG97851A (en) Hard dosed forms of almocalante and method for obtaining them
ES8706665A1 (es) Procedimiento de preparar nuevas sales de acidos carboxilicos, terapeuticamente utiles
ZA9610073B (en) Method of using beta-interferons to treat restenosis
ES8106156A1 (es) Un procedimiento para la preparacion de derivados de oxadia-zolotriazona
SU1016983A1 (ru) 3-Замещенные 6,8-диметилпиримидо-[5,4-е] [1,2,4]-триазин-5,7-диона, проявляющие противовоспалительную и противомикробную активность
JPS51148026A (en) Deodorizers
SU1095491A1 (ru) Средство дл лечени кардиалгий и легких форм ишемической болезни сердца "мебикар
MD346G2 (ro) Picoliden-4-izonicotinoilhidrazona dihidrată cu activitate tuberculostatică
IT8322221A0 (it) Impiego della fenpiramina quale farmaco antiaggregante piastrinico, vasodilatatore, antitrombotico e antianginoso.
NO904976D0 (no) Belagt slipekorn og anvendelse av dette.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 542807

Country of ref document: ES