ES2113101T3 - Metodo para purificar polipeptidos hidrofobos. - Google Patents

Metodo para purificar polipeptidos hidrofobos.

Info

Publication number
ES2113101T3
ES2113101T3 ES94914582T ES94914582T ES2113101T3 ES 2113101 T3 ES2113101 T3 ES 2113101T3 ES 94914582 T ES94914582 T ES 94914582T ES 94914582 T ES94914582 T ES 94914582T ES 2113101 T3 ES2113101 T3 ES 2113101T3
Authority
ES
Spain
Prior art keywords
purifying
vure
hydrophobic
hydrophobic polypeptides
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94914582T
Other languages
English (en)
Inventor
Tsunetomo Takei
Toshimitsu Aiba
Kaoru Sakai
Tetsuro Fujiwara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokyo Tanabe Co Ltd
Original Assignee
Tokyo Tanabe Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Tanabe Co Ltd filed Critical Tokyo Tanabe Co Ltd
Application granted granted Critical
Publication of ES2113101T3 publication Critical patent/ES2113101T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)

Abstract

UN METODO PARA PURIFICAR UN POLIPEPTIDO HIDROFOBICO POR CROMATOGRAFIA LIQUIDA DE ELEVADAS CARACTERISTICAS USANDO UNA FASE MOVIL QUE COMPRENDE UNA MEZCLA DE DISOLVENTE EN DONDE EL CONTENIDO DE ACIDO TRIFLUOROACETICO ES 3-10% (V/V) Y UN MATERIAL DE EMPAQUETADO QUE COMPRENDE ALCOHOL DE POLIVINILO. ESTE METODO ES USADO PORQUE UN SURFACTANTE DE PULMON PREPARADO DEL POLIPEPTIDO HIDROFOBICO PURIFICADO POR ESTE METODO TIENE UNA ACTIVIDAD SUPERFICIAL SUPERIOR A LA DE LOS POLIPEPTIDOS HIDROFOBICOS PURIFICADOS POR METODOS CONVENCIONALES.
ES94914582T 1993-04-30 1994-04-28 Metodo para purificar polipeptidos hidrofobos. Expired - Lifetime ES2113101T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10395793 1993-04-30

Publications (1)

Publication Number Publication Date
ES2113101T3 true ES2113101T3 (es) 1998-04-16

Family

ID=14367885

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94914582T Expired - Lifetime ES2113101T3 (es) 1993-04-30 1994-04-28 Metodo para purificar polipeptidos hidrofobos.

Country Status (11)

Country Link
US (1) US5648457A (es)
EP (1) EP0652227B1 (es)
KR (1) KR950701934A (es)
AT (1) ATE163426T1 (es)
AU (1) AU667438B2 (es)
CA (1) CA2136734A1 (es)
DE (1) DE69408631T2 (es)
DK (1) DK0652227T3 (es)
ES (1) ES2113101T3 (es)
GR (1) GR3026525T3 (es)
WO (1) WO1994025480A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2576895A (en) * 1994-12-07 1996-06-26 Tokyo Tanabe Company Limited Intermediate for producing surfactant peptide
ATE301674T1 (de) * 1996-05-15 2005-08-15 Altana Pharma Ag Verfahren zur trennung und bestimmung von hydrophoben proteinen durch dünnschichtchromatographie
EP1294403A2 (en) * 2000-06-14 2003-03-26 Corixa Corporation Tripeptide prodrug compounds
US6902734B2 (en) * 2000-08-07 2005-06-07 Centocor, Inc. Anti-IL-12 antibodies and compositions thereof
US6465432B1 (en) 2000-08-28 2002-10-15 Kraft Food Holdings, Inc. Isolated antioxidant peptides form casein and methods for preparing, isolating, and identifying antioxidant peptides
CN109053859B (zh) * 2018-08-09 2022-04-05 吉尔生化（上海）有限公司 一种针对中性疏水性多肽的纯化方法
CN111116702A (zh) * 2019-12-12 2020-05-08 河北博海生物工程开发有限公司 一种多肽提取组合物及试剂盒

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63501792A (ja) * 1985-09-26 1988-07-21 ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド 肺性界面活性蛋白質
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト，ジエフリー　エイ． 肺胞疎水性界面活性物質関連タンパク質
US4894330A (en) * 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
JPH01121299A (ja) * 1987-11-05 1989-05-12 Teijin Ltd ヒト肺サーファクタントアポ蛋白質
JP2615215B2 (ja) * 1989-08-22 1997-05-28 富士通株式会社 画像データ圧縮方式
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
JPH05294996A (ja) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤

Also Published As

Publication number Publication date
DE69408631T2 (de) 1998-07-02
EP0652227A4 (en) 1995-10-25
ATE163426T1 (de) 1998-03-15
EP0652227B1 (en) 1998-02-25
CA2136734A1 (en) 1994-11-10
GR3026525T3 (en) 1998-07-31
EP0652227A1 (en) 1995-05-10
KR950701934A (ko) 1995-05-17
AU6689494A (en) 1994-11-21
WO1994025480A1 (en) 1994-11-10
AU667438B2 (en) 1996-03-21
DK0652227T3 (da) 1998-12-21
US5648457A (en) 1997-07-15
DE69408631D1 (de) 1998-04-02

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