ES2099287T3 - Procedimiento de separacion de un peptido de una resina. - Google Patents
Procedimiento de separacion de un peptido de una resina.Info
- Publication number
- ES2099287T3 ES2099287T3 ES92922787T ES92922787T ES2099287T3 ES 2099287 T3 ES2099287 T3 ES 2099287T3 ES 92922787 T ES92922787 T ES 92922787T ES 92922787 T ES92922787 T ES 92922787T ES 2099287 T3 ES2099287 T3 ES 2099287T3
- Authority
- ES
- Spain
- Prior art keywords
- resin
- peptide
- hydrogen fluoride
- mixture
- separation procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
Abstract
EN LA SINTESIS DE UN PEPTIDO EN FASE SOLIDA, EL PEPTIDO DE ENLACE RESINA SE TRATA CON FLUORURO DE HIDROGENO PARA DISOCIAR EL PEPTIDO DE LA RESINA Y FORMAR UNA PRIMERA MEZCLA DE PEPTIDO, FLUORURO DE HIDROGENO Y RESINA. LA RESINA SE ELIMINA DE LA PRIMERA MEZCLA PARA OFRECER UNA SEGUNDA MEZCLA LIBRE DE RESINA QUE INCLUYE EL POLIPEPTIDO Y EL FLUORURO DE HIDROGENO. EL POLIPEPTIDO DE LA SEGUNDA MEZCLA SE SEPARA ENTONCES DEL FLUORURO DE HIDROGENO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/684,286 US5200507A (en) | 1991-04-12 | 1991-04-12 | Method of separating a peptide from a resin |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2099287T3 true ES2099287T3 (es) | 1997-05-16 |
Family
ID=24747442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92922787T Expired - Lifetime ES2099287T3 (es) | 1991-04-12 | 1992-03-13 | Procedimiento de separacion de un peptido de una resina. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5200507A (es) |
EP (1) | EP0579789B1 (es) |
JP (1) | JP3092941B2 (es) |
AT (1) | ATE147402T1 (es) |
AU (1) | AU660685B2 (es) |
CA (1) | CA2108170C (es) |
DE (1) | DE69216599T2 (es) |
ES (1) | ES2099287T3 (es) |
WO (1) | WO1992018525A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU5866496A (en) * | 1995-06-07 | 1996-12-30 | Immulogic Pharmaceutical Corporation | Process for cleavage of blocked peptide resins using liquid hydrogen fluoride |
US20030220258A1 (en) * | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of ischemic events |
EP1300418A1 (en) * | 2001-10-04 | 2003-04-09 | Erasmus Universiteit Rotterdam | Gene regulation by oligopeptides |
US7358330B2 (en) * | 2001-03-29 | 2008-04-15 | Biotempt B.V. | Immunoregulatory compositions |
US7786084B2 (en) * | 2001-12-21 | 2010-08-31 | Biotempt B.V. | Treatment of burns |
US7517529B2 (en) * | 2003-04-08 | 2009-04-14 | Biotempt B.V. | Treatment of type I diabetes |
EP1864692A1 (en) * | 2006-06-07 | 2007-12-12 | Biotempt B.V. | Use of peptides for the control of radiation injury |
AU2008215193B2 (en) * | 2007-02-12 | 2014-01-16 | Biotempt B.V. | Treatment of trauma hemorrhage with short oligopeptides |
US20120094910A1 (en) | 2009-04-06 | 2012-04-19 | Ananda Kuppanna | Improved process for the preparation of desmopressin or its pharmaceutically acceptable salts |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4130514A (en) * | 1978-02-10 | 1978-12-19 | Armour Pharmaceutical Company | Synthesis of peptides |
EP0246795A3 (en) * | 1986-05-20 | 1990-04-04 | Advanced Peptide Development Limited | Synthetic natriuretic peptides |
JP2815362B2 (ja) * | 1988-02-29 | 1998-10-27 | 中外製薬株式会社 | ベンズヒドリルアミン誘導体及びその製法 |
-
1991
- 1991-04-12 US US07/684,286 patent/US5200507A/en not_active Expired - Lifetime
-
1992
- 1992-03-13 AT AT92922787T patent/ATE147402T1/de not_active IP Right Cessation
- 1992-03-13 WO PCT/US1992/001978 patent/WO1992018525A1/en active IP Right Grant
- 1992-03-13 JP JP04510193A patent/JP3092941B2/ja not_active Expired - Fee Related
- 1992-03-13 DE DE69216599T patent/DE69216599T2/de not_active Expired - Lifetime
- 1992-03-13 EP EP92922787A patent/EP0579789B1/en not_active Expired - Lifetime
- 1992-03-13 AU AU18816/92A patent/AU660685B2/en not_active Ceased
- 1992-03-13 ES ES92922787T patent/ES2099287T3/es not_active Expired - Lifetime
- 1992-03-13 CA CA002108170A patent/CA2108170C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU1881692A (en) | 1992-11-17 |
CA2108170C (en) | 2002-08-13 |
WO1992018525A1 (en) | 1992-10-29 |
JP3092941B2 (ja) | 2000-09-25 |
EP0579789A1 (en) | 1994-01-26 |
ATE147402T1 (de) | 1997-01-15 |
EP0579789B1 (en) | 1997-01-08 |
US5200507A (en) | 1993-04-06 |
DE69216599T2 (de) | 1997-07-10 |
DE69216599D1 (de) | 1997-02-20 |
AU660685B2 (en) | 1995-07-06 |
CA2108170A1 (en) | 1992-10-13 |
JPH06506691A (ja) | 1994-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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