ES2064071T3 - Antigeno viral de hepatitis delta, procedimiento para su purificacion y su utilizacion. - Google Patents
Antigeno viral de hepatitis delta, procedimiento para su purificacion y su utilizacion.Info
- Publication number
- ES2064071T3 ES2064071T3 ES91830479T ES91830479T ES2064071T3 ES 2064071 T3 ES2064071 T3 ES 2064071T3 ES 91830479 T ES91830479 T ES 91830479T ES 91830479 T ES91830479 T ES 91830479T ES 2064071 T3 ES2064071 T3 ES 2064071T3
- Authority
- ES
- Spain
- Prior art keywords
- purification
- procedure
- viral antigen
- hepatitis delta
- hdag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 208000005331 Hepatitis D Diseases 0.000 title 1
- 208000037262 Hepatitis delta Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 208000029570 hepatitis D virus infection Diseases 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/28011—Hepeviridae
- C12N2770/28111—Hepevirus, e.g. hepatitis E virus
- C12N2770/28122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
SE DESCRIBE UN COMPUESTO QUE COMPRENDE POLIPEPTIDOS RECOMBINADOS DE TIPO HDAG Y PARECIDOS AL HDAG, CON UNA ANTIGENICIDAD COMPARABLE CON LA MOLECULA NATURAL EXPRESADA EN LAS CELULAS INFECTADAS DE HDV DEL HIGADO HUMANO. SE DESCRIBE TAMBIEN EL PROCESO PARA LA PURIFICACION DE DICHAS MOLECULAS Y LAS PRUEBAS DE INMUNIDAD PARA EL USO DE LAS MISMAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT67865A IT1241003B (it) | 1990-11-05 | 1990-11-05 | Procedimento per la purificazione di un polipeptide ricombinante hdag equivalente, polipeptide hdag equivalente e saggi immunologici che lo utilizzano |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2064071T3 true ES2064071T3 (es) | 1995-01-16 |
Family
ID=11305904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91830479T Expired - Lifetime ES2064071T3 (es) | 1990-11-05 | 1991-11-04 | Antigeno viral de hepatitis delta, procedimiento para su purificacion y su utilizacion. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0485347B1 (es) |
AT (1) | ATE111488T1 (es) |
DE (1) | DE69104012T2 (es) |
ES (1) | ES2064071T3 (es) |
HK (1) | HK1004267A1 (es) |
IT (1) | IT1241003B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1255660B (it) * | 1992-06-08 | 1995-11-09 | Sorin Biomedica Spa | Composizioni stabilizzate di hdag. |
US5445932A (en) * | 1992-11-17 | 1995-08-29 | The United States Of America As Represented By The Department Of Health And Human Services | Method for detection of a new marker associated with hepatitis delta virus infection |
US6844171B1 (en) * | 1998-07-02 | 2005-01-18 | President And Fellows Of Harvard College | Oligomerization of hepatitis delta antigen |
WO2008135274A2 (de) * | 2007-05-08 | 2008-11-13 | F. Hoffmann-La-Roche Ag | Verfahren zum nachweis spezifischer antikörper der immunglobulinklasse g |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE70308T1 (de) * | 1984-09-12 | 1991-12-15 | Chiron Corp | Hybridpartikel-immunogene. |
CA1338800C (en) * | 1986-06-17 | 1996-12-17 | Michael Houghton | Hepatitis delta and diagnostics and vaccines |
-
1990
- 1990-11-05 IT IT67865A patent/IT1241003B/it active IP Right Grant
-
1991
- 1991-11-04 EP EP91830479A patent/EP0485347B1/en not_active Expired - Lifetime
- 1991-11-04 ES ES91830479T patent/ES2064071T3/es not_active Expired - Lifetime
- 1991-11-04 DE DE69104012T patent/DE69104012T2/de not_active Expired - Fee Related
- 1991-11-04 AT AT91830479T patent/ATE111488T1/de active
-
1998
- 1998-04-23 HK HK98103386A patent/HK1004267A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0485347A3 (en) | 1992-07-29 |
DE69104012T2 (de) | 1995-05-11 |
IT9067865A1 (it) | 1992-05-05 |
IT1241003B (it) | 1993-12-27 |
HK1004267A1 (en) | 1998-11-20 |
IT9067865A0 (it) | 1990-11-05 |
ATE111488T1 (de) | 1994-09-15 |
EP0485347B1 (en) | 1994-09-14 |
DE69104012D1 (de) | 1994-10-20 |
EP0485347A2 (en) | 1992-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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