ES2003075A4 - Sintesis de peptidos en fase solida. - Google Patents
Sintesis de peptidos en fase solida.Info
- Publication number
- ES2003075A4 ES2003075A4 ES87870196T ES87870196T ES2003075A4 ES 2003075 A4 ES2003075 A4 ES 2003075A4 ES 87870196 T ES87870196 T ES 87870196T ES 87870196 T ES87870196 T ES 87870196T ES 2003075 A4 ES2003075 A4 ES 2003075A4
- Authority
- ES
- Spain
- Prior art keywords
- solid phase
- resin
- synthesis
- peptides
- union
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/34—Introducing sulfur atoms or sulfur-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/04—Reduction, e.g. hydrogenation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Abstract
UNA RESINA Y UN METODO PARA UTILIZAR LA RESINA PARA SINTESIS DE PEPTIDOS EN FASE SOLIDA. LA RESINA TIENE UNA UNION SULFOXIDO, QUE ES ESTABLE EN CONDICIONES DE ACIDO FUERTE. LA UNION SULFOXIDO PUEDE REDUCIRSE A UNION SULFURO, QUE PERMITE LA RUPTURA DEL PEPTIDO DE LA RESINA EN CONDICIONES ACIDAS SUAVES.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/946,558 US4764595A (en) | 1986-12-24 | 1986-12-24 | Resin support for solid phase peptide synthesis |
US06/947,651 US4801665A (en) | 1986-12-30 | 1986-12-30 | Resin method for making sulfoxide for solid phase peptide synthesis |
US07/031,823 US4764594A (en) | 1987-03-30 | 1987-03-30 | Resin support for solid phase peptide synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2003075A4 true ES2003075A4 (es) | 1988-10-16 |
Family
ID=27363965
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87870195T Pending ES2003862A4 (es) | 1986-12-24 | 1987-12-22 | Resina soporte para la sintesis de peptidos en fase solida. |
ES87870197T Pending ES2003864A4 (es) | 1986-12-24 | 1987-12-22 | Resina soporte para la sintesis de peptidos en fase solida. |
ES87870196T Pending ES2003075A4 (es) | 1986-12-24 | 1987-12-22 | Sintesis de peptidos en fase solida. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87870195T Pending ES2003862A4 (es) | 1986-12-24 | 1987-12-22 | Resina soporte para la sintesis de peptidos en fase solida. |
ES87870197T Pending ES2003864A4 (es) | 1986-12-24 | 1987-12-22 | Resina soporte para la sintesis de peptidos en fase solida. |
Country Status (2)
Country | Link |
---|---|
EP (3) | EP0274999A3 (es) |
ES (3) | ES2003862A4 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0372496A (ja) * | 1989-05-26 | 1991-03-27 | Applied Immune Sci Inc | 固相多重ペプチド合成 |
US5286789A (en) * | 1989-05-26 | 1994-02-15 | Applied Immune Sciences, Inc. | Solid phase multiple peptide synthesis |
CS103091A3 (en) * | 1991-04-12 | 1992-10-14 | Ustav Organicke Chemie A Bioch | Protected substituted benzhydrylamines as shoulders for the synthesis ofpeptides on solid phase, process of their preparation and use |
FR2688788B1 (fr) * | 1992-03-17 | 1994-05-13 | Bio Merieux | Composes hydrosolubles derives d'un homopolymere ou copolymere de l'anhydride maleique, et applications desdits composes au support de molecules biologiques. |
US5635598A (en) * | 1993-06-21 | 1997-06-03 | Selectide Corporation | Selectively cleavabe linners based on iminodiacetic acid esters for solid phase peptide synthesis |
US5798035A (en) * | 1996-10-03 | 1998-08-25 | Pharmacopeia, Inc. | High throughput solid phase chemical synthesis utilizing thin cylindrical reaction vessels useable for biological assay |
FR2767137A1 (fr) * | 1997-08-07 | 1999-02-12 | Bio Merieux | Compose chimique complexe, synthese et applications diverses dudit compose |
GB9717173D0 (en) * | 1997-08-13 | 1997-10-22 | Akzo Nobel Nv | Solid phase supports |
CA2222833A1 (en) * | 1997-11-28 | 1999-05-28 | Brent R. Stranix | Functional polymers bearing non-metal oxyacid derivatives on dimethylene spacers |
WO2000026262A2 (en) * | 1998-11-05 | 2000-05-11 | Mitokor | Functionalized polymeric substrates for binding molecular moieties |
JP2004513191A (ja) * | 2001-01-04 | 2004-04-30 | カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ | ペプチドおよび小分子有機合成用の新しいリンカーに基づく固相支持体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD88780A (es) * | ||||
NL239215A (es) * | 1958-05-19 | |||
US4507230A (en) * | 1982-05-12 | 1985-03-26 | Research Corporation | Peptide synthesis reagents and method of use |
US4575541A (en) * | 1984-05-24 | 1986-03-11 | Research Corporation | Polymer with sulfone-benzene appendage |
-
1987
- 1987-12-22 EP EP87870197A patent/EP0274999A3/en not_active Withdrawn
- 1987-12-22 EP EP87870195A patent/EP0274998A3/en not_active Withdrawn
- 1987-12-22 ES ES87870195T patent/ES2003862A4/es active Pending
- 1987-12-22 EP EP87870196A patent/EP0273895A3/en not_active Withdrawn
- 1987-12-22 ES ES87870197T patent/ES2003864A4/es active Pending
- 1987-12-22 ES ES87870196T patent/ES2003075A4/es active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2003862A4 (es) | 1988-12-01 |
EP0274999A3 (en) | 1988-12-14 |
EP0274998A3 (en) | 1988-12-14 |
EP0274998A2 (en) | 1988-07-20 |
EP0274999A2 (en) | 1988-07-20 |
EP0273895A2 (en) | 1988-07-06 |
EP0273895A3 (en) | 1988-12-21 |
ES2003864A4 (es) | 1988-12-01 |
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