ES2003862A4 - Resina soporte para la sintesis de peptidos en fase solida. - Google Patents
Resina soporte para la sintesis de peptidos en fase solida.Info
- Publication number
- ES2003862A4 ES2003862A4 ES87870195T ES87870195T ES2003862A4 ES 2003862 A4 ES2003862 A4 ES 2003862A4 ES 87870195 T ES87870195 T ES 87870195T ES 87870195 T ES87870195 T ES 87870195T ES 2003862 A4 ES2003862 A4 ES 2003862A4
- Authority
- ES
- Spain
- Prior art keywords
- peptides
- solid phase
- synthesis
- resin
- resin support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/34—Introducing sulfur atoms or sulfur-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/04—Reduction, e.g. hydrogenation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Abstract
LA INVENCION PROPORCIONA UNA RESINA PARA LA SINTESIS DE PEPTIDOS EN FASE SOLIDA, Y UN METODO PARA SINTETIZAR LA RESINA QUE TIENE UN ESLABON SULFOXIDO ESTABLE EN CONDICIONES DESPROTEGIDAS FRENTE A ACIDOS FUERTES. EL ESLABON SULFOXIDO PUEDE SER REDUCIDO A UN ESLABON SULFURO QUE PERMITE LA SEPARACION DEL PEPTIDO DE LA RESINA EN CONDICIONES ACIDAS SUAVES.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/946,558 US4764595A (en) | 1986-12-24 | 1986-12-24 | Resin support for solid phase peptide synthesis |
US06/947,651 US4801665A (en) | 1986-12-30 | 1986-12-30 | Resin method for making sulfoxide for solid phase peptide synthesis |
US07/031,823 US4764594A (en) | 1987-03-30 | 1987-03-30 | Resin support for solid phase peptide synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2003862A4 true ES2003862A4 (es) | 1988-12-01 |
Family
ID=27363965
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87870196T Pending ES2003075A4 (es) | 1986-12-24 | 1987-12-22 | Sintesis de peptidos en fase solida. |
ES87870195T Pending ES2003862A4 (es) | 1986-12-24 | 1987-12-22 | Resina soporte para la sintesis de peptidos en fase solida. |
ES87870197T Pending ES2003864A4 (es) | 1986-12-24 | 1987-12-22 | Resina soporte para la sintesis de peptidos en fase solida. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87870196T Pending ES2003075A4 (es) | 1986-12-24 | 1987-12-22 | Sintesis de peptidos en fase solida. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87870197T Pending ES2003864A4 (es) | 1986-12-24 | 1987-12-22 | Resina soporte para la sintesis de peptidos en fase solida. |
Country Status (2)
Country | Link |
---|---|
EP (3) | EP0274999A3 (es) |
ES (3) | ES2003075A4 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5286789A (en) * | 1989-05-26 | 1994-02-15 | Applied Immune Sciences, Inc. | Solid phase multiple peptide synthesis |
JPH0372496A (ja) * | 1989-05-26 | 1991-03-27 | Applied Immune Sci Inc | 固相多重ペプチド合成 |
CS103091A3 (en) * | 1991-04-12 | 1992-10-14 | Ustav Organicke Chemie A Bioch | Protected substituted benzhydrylamines as shoulders for the synthesis ofpeptides on solid phase, process of their preparation and use |
FR2688788B1 (fr) * | 1992-03-17 | 1994-05-13 | Bio Merieux | Composes hydrosolubles derives d'un homopolymere ou copolymere de l'anhydride maleique, et applications desdits composes au support de molecules biologiques. |
AU689116B2 (en) * | 1993-06-21 | 1998-03-26 | Aventisub Ii Inc. | Selectively cleavable linkers based on iminodiacetic acid ester bonds |
US5798035A (en) | 1996-10-03 | 1998-08-25 | Pharmacopeia, Inc. | High throughput solid phase chemical synthesis utilizing thin cylindrical reaction vessels useable for biological assay |
FR2767137A1 (fr) * | 1997-08-07 | 1999-02-12 | Bio Merieux | Compose chimique complexe, synthese et applications diverses dudit compose |
GB9717173D0 (en) * | 1997-08-13 | 1997-10-22 | Akzo Nobel Nv | Solid phase supports |
CA2222833A1 (en) * | 1997-11-28 | 1999-05-28 | Brent R. Stranix | Functional polymers bearing non-metal oxyacid derivatives on dimethylene spacers |
WO2000026262A2 (en) * | 1998-11-05 | 2000-05-11 | Mitokor | Functionalized polymeric substrates for binding molecular moieties |
JP2004513191A (ja) * | 2001-01-04 | 2004-04-30 | カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ | ペプチドおよび小分子有機合成用の新しいリンカーに基づく固相支持体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD88780A (es) * | ||||
NL239215A (es) * | 1958-05-19 | |||
US4507230A (en) * | 1982-05-12 | 1985-03-26 | Research Corporation | Peptide synthesis reagents and method of use |
US4575541A (en) * | 1984-05-24 | 1986-03-11 | Research Corporation | Polymer with sulfone-benzene appendage |
-
1987
- 1987-12-22 EP EP87870197A patent/EP0274999A3/en not_active Withdrawn
- 1987-12-22 EP EP87870196A patent/EP0273895A3/en not_active Withdrawn
- 1987-12-22 ES ES87870196T patent/ES2003075A4/es active Pending
- 1987-12-22 ES ES87870195T patent/ES2003862A4/es active Pending
- 1987-12-22 ES ES87870197T patent/ES2003864A4/es active Pending
- 1987-12-22 EP EP87870195A patent/EP0274998A3/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP0274999A3 (en) | 1988-12-14 |
EP0274998A2 (en) | 1988-07-20 |
ES2003075A4 (es) | 1988-10-16 |
EP0274999A2 (en) | 1988-07-20 |
EP0273895A2 (en) | 1988-07-06 |
EP0274998A3 (en) | 1988-12-14 |
EP0273895A3 (en) | 1988-12-21 |
ES2003864A4 (es) | 1988-12-01 |
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