ATE20071T1 - Verfahren zur reinigung von sekretin. - Google Patents
Verfahren zur reinigung von sekretin.Info
- Publication number
- ATE20071T1 ATE20071T1 AT83101231T AT83101231T ATE20071T1 AT E20071 T1 ATE20071 T1 AT E20071T1 AT 83101231 T AT83101231 T AT 83101231T AT 83101231 T AT83101231 T AT 83101231T AT E20071 T1 ATE20071 T1 AT E20071T1
- Authority
- AT
- Austria
- Prior art keywords
- secretine
- purification
- secretin
- eluant
- reversed
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- KKNIUBFRGPFELP-UHFFFAOYSA-N secretolin Chemical compound N=1C=CNC=1CC(N)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NCC(=O)NC(C(C)O)C(=O)NC(C(=O)NC(C(=O)NC(CO)C(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(O)=O)C(C)O)CC1=CC=CC=C1 KKNIUBFRGPFELP-UHFFFAOYSA-N 0.000 title 1
- 102100037505 Secretin Human genes 0.000 abstract 2
- 108010086019 Secretin Proteins 0.000 abstract 2
- 229960002101 secretin Drugs 0.000 abstract 2
- OWMZNFCDEHGFEP-NFBCVYDUSA-N secretin human Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O)[C@@H](C)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)C1=CC=CC=C1 OWMZNFCDEHGFEP-NFBCVYDUSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000004007 reversed phase HPLC Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/645—Secretins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57021311A JPS58140024A (ja) | 1982-02-15 | 1982-02-15 | セクレチンの精製方法 |
| EP83101231A EP0087066B1 (de) | 1982-02-15 | 1983-02-09 | Verfahren zur Reinigung von Sekretin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE20071T1 true ATE20071T1 (de) | 1986-06-15 |
Family
ID=12051600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83101231T ATE20071T1 (de) | 1982-02-15 | 1983-02-09 | Verfahren zur reinigung von sekretin. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4533494A (de) |
| EP (1) | EP0087066B1 (de) |
| JP (1) | JPS58140024A (de) |
| AT (1) | ATE20071T1 (de) |
| DE (1) | DE3363641D1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE454513B (sv) * | 1985-03-11 | 1988-05-09 | Kabigen Ab | Humant sekretin samt kompositioner innehallande detta |
| NZ212523A (en) * | 1985-06-24 | 1989-01-06 | Univ Massey | Mobile phase for purification of proteins by high performance liquid chromatography |
| US5202029A (en) * | 1991-03-13 | 1993-04-13 | Caron Kabushiki Kaisha | Process for purification of hmg-coa reductase inhibitors |
| US5250660A (en) * | 1991-11-12 | 1993-10-05 | Eli Lilly And Company | Peptide purification process |
| US6197746B1 (en) * | 1998-05-19 | 2001-03-06 | Repligen Corporation | Method of using secretin for treating autism |
| JP2002501616A (ja) | 1997-05-19 | 2002-01-15 | リプリゲン コーポレーション | 自閉的症候群を鑑別診断および治療する際の助けとするための方法 |
| AU3227000A (en) * | 1999-02-10 | 2000-08-29 | Ontogeny, Inc. | Methods of inducing insulin positive progenitor cells |
| JP5638177B2 (ja) * | 2004-02-11 | 2014-12-10 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド |
| CN104897843B (zh) * | 2015-06-24 | 2017-01-11 | 南京信息工程大学 | 一种茶树嫩芽内源激素含量的测定方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58126813A (ja) * | 1982-01-22 | 1983-07-28 | Eisai Co Ltd | 粗セクレチンの精製法 |
-
1982
- 1982-02-15 JP JP57021311A patent/JPS58140024A/ja active Pending
-
1983
- 1983-02-09 DE DE8383101231T patent/DE3363641D1/de not_active Expired
- 1983-02-09 EP EP83101231A patent/EP0087066B1/de not_active Expired
- 1983-02-09 AT AT83101231T patent/ATE20071T1/de not_active IP Right Cessation
- 1983-02-10 US US06/465,691 patent/US4533494A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0087066A1 (de) | 1983-08-31 |
| US4533494A (en) | 1985-08-06 |
| EP0087066B1 (de) | 1986-05-28 |
| JPS58140024A (ja) | 1983-08-19 |
| DE3363641D1 (en) | 1986-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |