ATE20071T1 - Verfahren zur reinigung von sekretin. - Google Patents
Verfahren zur reinigung von sekretin.Info
- Publication number
- ATE20071T1 ATE20071T1 AT83101231T AT83101231T ATE20071T1 AT E20071 T1 ATE20071 T1 AT E20071T1 AT 83101231 T AT83101231 T AT 83101231T AT 83101231 T AT83101231 T AT 83101231T AT E20071 T1 ATE20071 T1 AT E20071T1
- Authority
- AT
- Austria
- Prior art keywords
- secretine
- purification
- secretin
- eluant
- reversed
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- KKNIUBFRGPFELP-UHFFFAOYSA-N secretolin Chemical compound N=1C=CNC=1CC(N)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NCC(=O)NC(C(C)O)C(=O)NC(C(=O)NC(C(=O)NC(CO)C(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(O)=O)C(C)O)CC1=CC=CC=C1 KKNIUBFRGPFELP-UHFFFAOYSA-N 0.000 title 1
- 102100037505 Secretin Human genes 0.000 abstract 2
- 108010086019 Secretin Proteins 0.000 abstract 2
- 229960002101 secretin Drugs 0.000 abstract 2
- OWMZNFCDEHGFEP-NFBCVYDUSA-N secretin human Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O)[C@@H](C)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)C1=CC=CC=C1 OWMZNFCDEHGFEP-NFBCVYDUSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000004007 reversed phase HPLC Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/645—Secretins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57021311A JPS58140024A (ja) | 1982-02-15 | 1982-02-15 | セクレチンの精製方法 |
| EP83101231A EP0087066B1 (de) | 1982-02-15 | 1983-02-09 | Verfahren zur Reinigung von Sekretin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE20071T1 true ATE20071T1 (de) | 1986-06-15 |
Family
ID=12051600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83101231T ATE20071T1 (de) | 1982-02-15 | 1983-02-09 | Verfahren zur reinigung von sekretin. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4533494A (de) |
| EP (1) | EP0087066B1 (de) |
| JP (1) | JPS58140024A (de) |
| AT (1) | ATE20071T1 (de) |
| DE (1) | DE3363641D1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE454513B (sv) * | 1985-03-11 | 1988-05-09 | Kabigen Ab | Humant sekretin samt kompositioner innehallande detta |
| NZ212523A (en) * | 1985-06-24 | 1989-01-06 | Univ Massey | Mobile phase for purification of proteins by high performance liquid chromatography |
| US5202029A (en) * | 1991-03-13 | 1993-04-13 | Caron Kabushiki Kaisha | Process for purification of hmg-coa reductase inhibitors |
| US5250660A (en) * | 1991-11-12 | 1993-10-05 | Eli Lilly And Company | Peptide purification process |
| US6020310A (en) * | 1997-05-19 | 2000-02-01 | Repligen Corporation | Method for assisting in differential diagnosis and treatment of autistic syndromes |
| US6197746B1 (en) | 1998-05-19 | 2001-03-06 | Repligen Corporation | Method of using secretin for treating autism |
| AU3227000A (en) * | 1999-02-10 | 2000-08-29 | Ontogeny, Inc. | Methods of inducing insulin positive progenitor cells |
| JP5638177B2 (ja) * | 2004-02-11 | 2014-12-10 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド |
| CN104897843B (zh) * | 2015-06-24 | 2017-01-11 | 南京信息工程大学 | 一种茶树嫩芽内源激素含量的测定方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58126813A (ja) * | 1982-01-22 | 1983-07-28 | Eisai Co Ltd | 粗セクレチンの精製法 |
-
1982
- 1982-02-15 JP JP57021311A patent/JPS58140024A/ja active Pending
-
1983
- 1983-02-09 AT AT83101231T patent/ATE20071T1/de not_active IP Right Cessation
- 1983-02-09 DE DE8383101231T patent/DE3363641D1/de not_active Expired
- 1983-02-09 EP EP83101231A patent/EP0087066B1/de not_active Expired
- 1983-02-10 US US06/465,691 patent/US4533494A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3363641D1 (en) | 1986-07-03 |
| US4533494A (en) | 1985-08-06 |
| JPS58140024A (ja) | 1983-08-19 |
| EP0087066A1 (de) | 1983-08-31 |
| EP0087066B1 (de) | 1986-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |