ES2103253T1 - Procedimiento para la preparacion de un dicloruro de acido dicarboxilico. - Google Patents
Procedimiento para la preparacion de un dicloruro de acido dicarboxilico.Info
- Publication number
- ES2103253T1 ES2103253T1 ES96919778T ES96919778T ES2103253T1 ES 2103253 T1 ES2103253 T1 ES 2103253T1 ES 96919778 T ES96919778 T ES 96919778T ES 96919778 T ES96919778 T ES 96919778T ES 2103253 T1 ES2103253 T1 ES 2103253T1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- acid
- dicarboxilico
- acid dichloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000000010 aprotic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Polyamides (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION DE DICLORURO DEL ACIDO S-(()-())-5-[[][[]2(()ACETILOXI())-1-OXOPROPIL[]][]]-AMINO-2,4,6-TRIYODO-1,3BENCENODICARBOXILICO DE FORMULA (I) QUE COMPRENDE LA REACCION ENTRE CLORURO DEL ACIDO S-(()-())-[[]2(()ACETILOXI())[]]PROPIONICO Y DICLORURO DEL ACIDO 5-AMINO-2,4,6TRIYODO-1,3-BENCENODICARBOXILICO, EN UN SOLVENTE DIPOLAR APROTICO Y EN PRESENCIA DE UN ACIDO HALOGENHIDRICO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI951048A IT1274550B (it) | 1995-05-23 | 1995-05-23 | Processo per la preparazione del dicloruro dell'acido s-5-¬¬2- (acetilossi)-1-ossopropil|ammino|-2,4,6-triiodo-1,3- benzendicarbossilico |
IT95RM000548 IT1281319B1 (it) | 1995-08-04 | 1995-08-04 | Procedimento per la preparazione di dicloruro dell'acido s-5-<<2- (acetilossi)-1-ossopropil>ammino>-2,4,6-triiodo-1,3-benzendi- |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2103253T1 true ES2103253T1 (es) | 1997-09-16 |
ES2103253T3 ES2103253T3 (es) | 2000-04-01 |
Family
ID=26331280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96919778T Expired - Lifetime ES2103253T3 (es) | 1995-05-23 | 1996-05-17 | Procedimiento para la preparacion de un dicloruro de acido dicarboxilico. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5672735A (es) |
EP (1) | EP0773925B1 (es) |
JP (2) | JP4012567B2 (es) |
KR (1) | KR100269080B1 (es) |
CN (1) | CN1068582C (es) |
AT (1) | ATE189674T1 (es) |
AU (1) | AU698623B2 (es) |
BR (1) | BR9606394A (es) |
CA (1) | CA2195634C (es) |
CZ (1) | CZ290363B6 (es) |
DE (2) | DE69606601T2 (es) |
ES (1) | ES2103253T3 (es) |
GR (1) | GR970300028T1 (es) |
HU (1) | HU216537B (es) |
IL (1) | IL118358A (es) |
NO (1) | NO313697B1 (es) |
PL (1) | PL187308B1 (es) |
PT (1) | PT773925E (es) |
SI (1) | SI9620010B (es) |
SK (1) | SK8897A3 (es) |
WO (1) | WO1996037460A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1289521B1 (it) * | 1996-12-24 | 1998-10-15 | Zambon Spa | Processo per la purificazione di un intermedio |
IT1289520B1 (it) * | 1996-12-24 | 1998-10-15 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati |
IT1289519B1 (it) * | 1996-12-24 | 1998-10-15 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati |
EP2230227A1 (en) | 2009-03-20 | 2010-09-22 | Bracco Imaging S.p.A | Process for the preparation of triiodinated carboxylic aromatic derivatives |
EP2243767A1 (en) | 2009-04-21 | 2010-10-27 | Bracco Imaging S.p.A | Process for the iodination of aromatic compounds |
PT105770B (pt) * | 2011-06-24 | 2013-07-08 | Hovione Farmaciencia S A | Novo intermediário e seu uso na preparação de agente de contrate triiodado |
EP2931696B1 (en) * | 2012-12-11 | 2018-08-22 | Bracco Imaging S.p.A | Continuous process for the preparation of (s)-2-acetyloxypropionic acid |
LT3066071T (lt) | 2013-11-05 | 2018-09-10 | Bracco Imaging S.P.A. | Jopamidolio gamybos būdas |
CA2949433C (en) | 2014-06-10 | 2022-05-03 | Bracco Imaging Spa | Method for the preparation of (s)-2-acetyloxypropionic acid and derivatives thereof |
WO2018104228A1 (en) | 2016-12-05 | 2018-06-14 | Bracco Imaging Spa | Mechanochemical synthesis of radiographic agents intermediates |
FR3062850B1 (fr) | 2017-02-10 | 2020-01-31 | Guerbet | Procede de preparation monotope de composes organo-iodes |
FR3084668A1 (fr) | 2018-08-02 | 2020-02-07 | Guerbet | Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH608189A5 (es) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
CH626873A5 (es) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa | |
DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
IT1256162B (it) * | 1992-10-27 | 1995-11-29 | Zambon Spa | Processo per la preparazione di un intermedio della sintesi organica |
IT1274027B (it) * | 1994-03-03 | 1997-07-14 | Zambon Spa | Processo per la preparazione e purificazione di mezzi di contrasto iodurati |
-
1996
- 1996-05-17 PL PL96318284A patent/PL187308B1/pl unknown
- 1996-05-17 JP JP53534696A patent/JP4012567B2/ja not_active Expired - Lifetime
- 1996-05-17 AT AT96919778T patent/ATE189674T1/de not_active IP Right Cessation
- 1996-05-17 WO PCT/EP1996/002104 patent/WO1996037460A1/en active IP Right Grant
- 1996-05-17 SI SI9620010A patent/SI9620010B/sl unknown
- 1996-05-17 CN CN96190525A patent/CN1068582C/zh not_active Expired - Lifetime
- 1996-05-17 KR KR1019970700403A patent/KR100269080B1/ko not_active IP Right Cessation
- 1996-05-17 CZ CZ1997186A patent/CZ290363B6/cs not_active IP Right Cessation
- 1996-05-17 HU HU9700190A patent/HU216537B/hu unknown
- 1996-05-17 DE DE69606601T patent/DE69606601T2/de not_active Expired - Lifetime
- 1996-05-17 EP EP96919778A patent/EP0773925B1/en not_active Expired - Lifetime
- 1996-05-17 AU AU58188/96A patent/AU698623B2/en not_active Expired
- 1996-05-17 PT PT96919778T patent/PT773925E/pt unknown
- 1996-05-17 BR BR9606394A patent/BR9606394A/pt not_active Application Discontinuation
- 1996-05-17 ES ES96919778T patent/ES2103253T3/es not_active Expired - Lifetime
- 1996-05-17 SK SK88-97A patent/SK8897A3/sk unknown
- 1996-05-17 DE DE0773925T patent/DE773925T1/de active Pending
- 1996-05-17 CA CA002195634A patent/CA2195634C/en not_active Expired - Lifetime
- 1996-05-21 US US08/651,474 patent/US5672735A/en not_active Expired - Lifetime
- 1996-05-22 IL IL11835896A patent/IL118358A/xx not_active IP Right Cessation
-
1997
- 1997-01-21 NO NO19970262A patent/NO313697B1/no not_active IP Right Cessation
- 1997-09-30 GR GR970300028T patent/GR970300028T1/el unknown
-
2007
- 2007-06-19 JP JP2007160804A patent/JP4675355B2/ja not_active Expired - Lifetime
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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