ES2090244T3 - Procedimiento para prevenir, estabilizar u ocasionar la regresion de la aterosclerosis usando una combinacion de un medicamento para disminuir el colesterol y un inhibidor de la ace. - Google Patents

Procedimiento para prevenir, estabilizar u ocasionar la regresion de la aterosclerosis usando una combinacion de un medicamento para disminuir el colesterol y un inhibidor de la ace.

Info

Publication number
ES2090244T3
ES2090244T3 ES91304232T ES91304232T ES2090244T3 ES 2090244 T3 ES2090244 T3 ES 2090244T3 ES 91304232 T ES91304232 T ES 91304232T ES 91304232 T ES91304232 T ES 91304232T ES 2090244 T3 ES2090244 T3 ES 2090244T3
Authority
ES
Spain
Prior art keywords
atherosclerosis
combination
ace inhibitor
regression
stabilize
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91304232T
Other languages
English (en)
Inventor
James L Bergey
James C Kawano
Werner Tschollar
Cary S Yonce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of ES2090244T3 publication Critical patent/ES2090244T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

SE PROPORCIONA UN METODO PARA HACER MAS LENTA LA PROGRESION DE ATEROSCLEROSIS EN PACIENTES HIPERTENSOS O NORMOTENSOS Y REDUCIR O ELIMINAR LAS LESIONES ATEROSCLEROTICAS EN TALES PACIENTES MEDIANTE EL SUMINISTRO DE UNA COMBINACION DE UN MEDICAMENTO BAJADOR DEL COLESTEROL COMO PRAVASTATIN, Y UN INHIBIDOR ACE, ESPECIALMENTE UNO CONTENIENDO UNA MITAD DE MERCAPTO, TAL COMO CAPTOPRIL O ZOFENOPRIL.
ES91304232T 1990-05-15 1991-05-10 Procedimiento para prevenir, estabilizar u ocasionar la regresion de la aterosclerosis usando una combinacion de un medicamento para disminuir el colesterol y un inhibidor de la ace. Expired - Lifetime ES2090244T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52426690A 1990-05-15 1990-05-15

Publications (1)

Publication Number Publication Date
ES2090244T3 true ES2090244T3 (es) 1996-10-16

Family

ID=24088484

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91304232T Expired - Lifetime ES2090244T3 (es) 1990-05-15 1991-05-10 Procedimiento para prevenir, estabilizar u ocasionar la regresion de la aterosclerosis usando una combinacion de un medicamento para disminuir el colesterol y un inhibidor de la ace.

Country Status (15)

Country Link
EP (1) EP0457514B1 (es)
JP (1) JPH04226921A (es)
KR (1) KR100200467B1 (es)
AT (1) ATE141514T1 (es)
AU (1) AU651579B2 (es)
CA (1) CA2040865C (es)
DE (1) DE69121464T2 (es)
DK (1) DK0457514T3 (es)
ES (1) ES2090244T3 (es)
GR (1) GR3021703T3 (es)
HU (1) HU212102B (es)
IE (1) IE77637B1 (es)
NZ (1) NZ237929A (es)
PT (1) PT97660B (es)
ZA (1) ZA913509B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5157025A (en) * 1991-04-01 1992-10-20 E. R. Squibb & Sons, Inc. Method for lowering serum cholesterol employing a phosphorus containing ace inhibitor alone or in combination with a cholesterol lowering drug
AU3473193A (en) * 1992-01-17 1993-08-03 Procter & Gamble Company, The Treatment for atherosclerosis
AU1095695A (en) * 1993-11-09 1995-05-29 Brigham And Women's Hospital Hmg-coa reductase inhibitors in the normalization of vascular endothelial dysfunction
DE4402379C2 (de) * 1994-01-27 1997-09-25 Lohmann Therapie Syst Lts Orale Arzneiform mit sauren Wirkstoffen und Verfahren zu ihrer Herstellung
CA2186606A1 (en) * 1994-03-29 1995-10-05 Edward B. Nelson Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles
EP1514543A1 (en) 1997-08-29 2005-03-16 Pfizer Inc. Combination therapy comprising atorvastatin and an antihypertensive agent
SI20305A (sl) 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
AU2007200367B2 (en) * 1999-02-06 2010-04-08 Astrazeneca Ab Use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors for the manufacture of a medicament for the treatment of diabetic neuropathy
GB0001662D0 (en) 1999-02-06 2000-03-15 Zeneca Ltd Pharmaceutical compositions
US6172441B1 (en) 1999-06-28 2001-01-09 Visteon Global Technologies, Inc. Rotor assembly
HUP0203326A3 (en) 1999-08-30 2003-04-28 Sanofi Aventis Deutschland Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
US6576256B2 (en) 2001-08-28 2003-06-10 The Brigham And Women's Hospital, Inc. Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
US6669955B2 (en) * 2001-08-28 2003-12-30 Longwood Pharmaceutical Research, Inc. Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
AU2003227691B2 (en) * 2002-05-03 2008-05-15 Hexal Ag Stable pharmaceutical formulation for a combination of a statin and an ace inhibitor
AR040588A1 (es) 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
ATE406364T1 (de) 2003-03-07 2008-09-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
CN1756756A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
WO2004085448A2 (en) * 2003-03-19 2004-10-07 Genzyme Corporation Unsaturated phosphinyl-phosphonate phosphate transport inhibitors
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
CN1903364B (zh) * 2005-07-26 2011-06-22 安徽省现代中药研究中心 含有血管紧张素转化酶抑制剂和苯氧酸类化合物的药物组合物
CN102300571A (zh) * 2008-12-01 2011-12-28 英沃兹科医疗有限公司 包括肾素—血管紧张素醛固酮系统抑制剂和硫辛酸化合物的组合物，及其用于肾素—血管紧张素醛固酮系统相关病症的治疗

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3536687A1 (de) * 1985-10-15 1987-04-16 Hoechst Ag Verfahren zur behandlung von atherosklerose, thrombose und der peripheren gefaesskrankheit

Also Published As

Publication number Publication date
DK0457514T3 (da) 1996-09-16
CA2040865A1 (en) 1991-11-16
HU911620D0 (en) 1991-11-28
CA2040865C (en) 2002-07-23
PT97660B (pt) 1998-09-30
AU7627091A (en) 1991-11-21
HUT57993A (en) 1992-01-28
KR100200467B1 (ko) 1999-06-15
EP0457514B1 (en) 1996-08-21
IE911431A1 (en) 1991-11-20
GR3021703T3 (en) 1997-02-28
DE69121464T2 (de) 1997-03-27
AU651579B2 (en) 1994-07-28
JPH04226921A (ja) 1992-08-17
ATE141514T1 (de) 1996-09-15
NZ237929A (en) 1997-06-24
ZA913509B (en) 1992-02-26
IE77637B1 (en) 1997-12-31
KR910019614A (ko) 1991-12-19
DE69121464D1 (de) 1996-09-26
HU212102B (en) 1996-02-28
PT97660A (pt) 1992-02-28
EP0457514A1 (en) 1991-11-21

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