ES2115741T3 - Utilizacion de un inhibidor directo de la trombina para la preparacion de un medicamento con actividad trombolitica. - Google Patents
Utilizacion de un inhibidor directo de la trombina para la preparacion de un medicamento con actividad trombolitica.Info
- Publication number
- ES2115741T3 ES2115741T3 ES93402136T ES93402136T ES2115741T3 ES 2115741 T3 ES2115741 T3 ES 2115741T3 ES 93402136 T ES93402136 T ES 93402136T ES 93402136 T ES93402136 T ES 93402136T ES 2115741 T3 ES2115741 T3 ES 2115741T3
- Authority
- ES
- Spain
- Prior art keywords
- inhibitor
- direct
- thrombine
- preparation
- medicinal product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UTILIZACION DE UN INHIBIDOR DIRECTO DE LA TROMBINA PARA LA FABRICACION DE UN MEDICAMENTO CON ACTIVIDAD TROMBOLITICA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9210833A FR2695562B1 (fr) | 1992-09-11 | 1992-09-11 | Utilisation d'un inhibiteur direct de la thrombine pour la fabrication d'un médicament à activité thrombolytique. |
FR9210833 | 1992-09-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2115741T3 true ES2115741T3 (es) | 1998-07-01 |
ES2115741T4 ES2115741T4 (es) | 2012-07-04 |
Family
ID=9433400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93402136T Expired - Lifetime ES2115741T4 (es) | 1992-09-11 | 1993-09-02 | Utilización de un inhibidor directo de la trombina para la preparación de un medicamento con actividad trombolítica |
Country Status (18)
Country | Link |
---|---|
US (1) | US5583113A (es) |
EP (1) | EP0589741B1 (es) |
JP (1) | JPH06228007A (es) |
KR (1) | KR100261526B1 (es) |
CN (1) | CN1066961C (es) |
AT (1) | ATE163856T1 (es) |
AU (1) | AU4628193A (es) |
CA (1) | CA2105888C (es) |
CZ (1) | CZ188893A3 (es) |
DE (1) | DE69317343T2 (es) |
DK (1) | DK0589741T3 (es) |
ES (1) | ES2115741T4 (es) |
FR (1) | FR2695562B1 (es) |
IL (1) | IL106981A (es) |
NO (1) | NO306537B1 (es) |
SK (1) | SK96993A3 (es) |
TW (1) | TW284691B (es) |
ZA (1) | ZA936707B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830448A (en) * | 1994-06-16 | 1998-11-03 | Genentech, Inc. | Compositions and methods for the treatment of tumors |
DE4421052A1 (de) | 1994-06-17 | 1995-12-21 | Basf Ag | Neue Thrombininhibitoren, ihre Herstellung und Verwendung |
CN1198839C (zh) * | 1995-02-17 | 2005-04-27 | 艾伯特有限及两合公司 | 作为凝血酶抑制剂的新的二肽脒类 |
US5840733A (en) | 1996-07-01 | 1998-11-24 | Redcell, Canada, Inc. | Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes |
BR9907112A (pt) | 1998-01-26 | 2000-10-24 | Basf Ag | Composto, medicamento, e, uso de um composto |
CN101598725B (zh) * | 2009-06-23 | 2012-07-18 | 南通大学附属医院 | 阿加曲班在血细胞和生化常规分析中的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4258192A (en) * | 1977-12-16 | 1981-03-24 | Mitsubishi Chemical Industries Limited | N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US4318904A (en) * | 1980-04-25 | 1982-03-09 | Research Corporation | Peptide affinity labels for thrombin and other trypsin-like proteases |
US4929602A (en) * | 1987-11-25 | 1990-05-29 | Scripps Clinic And Research Foundation | Method of inhibiting platelet dependent arterial thrombosis |
US5196404B1 (en) * | 1989-08-18 | 1996-09-10 | Biogen Inc | Inhibitors of thrombin |
-
1992
- 1992-09-11 FR FR9210833A patent/FR2695562B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-02 EP EP93402136A patent/EP0589741B1/fr not_active Expired - Lifetime
- 1993-09-02 ES ES93402136T patent/ES2115741T4/es not_active Expired - Lifetime
- 1993-09-02 DE DE69317343T patent/DE69317343T2/de not_active Expired - Lifetime
- 1993-09-02 AT AT93402136T patent/ATE163856T1/de not_active IP Right Cessation
- 1993-09-02 DK DK93402136T patent/DK0589741T3/da active
- 1993-09-10 AU AU46281/93A patent/AU4628193A/en not_active Abandoned
- 1993-09-10 CZ CZ931888A patent/CZ188893A3/cs unknown
- 1993-09-10 JP JP5225606A patent/JPH06228007A/ja active Pending
- 1993-09-10 IL IL10698193A patent/IL106981A/en not_active IP Right Cessation
- 1993-09-10 KR KR1019930018230A patent/KR100261526B1/ko not_active IP Right Cessation
- 1993-09-10 NO NO933235A patent/NO306537B1/no not_active IP Right Cessation
- 1993-09-10 SK SK969-93A patent/SK96993A3/sk unknown
- 1993-09-10 CA CA002105888A patent/CA2105888C/fr not_active Expired - Lifetime
- 1993-09-10 ZA ZA936707A patent/ZA936707B/xx unknown
- 1993-09-10 CN CN93117197A patent/CN1066961C/zh not_active Expired - Lifetime
- 1993-09-10 TW TW082107438A patent/TW284691B/zh active
-
1995
- 1995-02-13 US US08/387,382 patent/US5583113A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR100261526B1 (ko) | 2000-07-15 |
ZA936707B (en) | 1994-03-30 |
TW284691B (es) | 1996-09-01 |
EP0589741B1 (fr) | 1998-03-11 |
CN1066961C (zh) | 2001-06-13 |
FR2695562B1 (fr) | 1994-10-14 |
IL106981A0 (en) | 1993-12-28 |
DK0589741T3 (da) | 1998-12-21 |
AU4628193A (en) | 1994-03-17 |
DE69317343T2 (de) | 1998-10-08 |
CZ188893A3 (en) | 1994-03-16 |
CA2105888C (fr) | 2008-04-15 |
US5583113A (en) | 1996-12-10 |
NO933235L (no) | 1994-03-14 |
FR2695562A1 (fr) | 1994-03-18 |
SK96993A3 (en) | 1994-08-10 |
EP0589741A1 (fr) | 1994-03-30 |
ES2115741T4 (es) | 2012-07-04 |
ATE163856T1 (de) | 1998-03-15 |
NO306537B1 (no) | 1999-11-22 |
CA2105888A1 (fr) | 1994-03-12 |
IL106981A (en) | 1999-03-12 |
DE69317343D1 (de) | 1998-04-16 |
NO933235D0 (no) | 1993-09-10 |
KR940006600A (ko) | 1994-04-25 |
JPH06228007A (ja) | 1994-08-16 |
CN1087015A (zh) | 1994-05-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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