ES2088402T3 - Procesos para producir acidos 5-fluorobenzoicos y sus intermedios. - Google Patents

Procesos para producir acidos 5-fluorobenzoicos y sus intermedios.

Info

Publication number
ES2088402T3
ES2088402T3 ES90121977T ES90121977T ES2088402T3 ES 2088402 T3 ES2088402 T3 ES 2088402T3 ES 90121977 T ES90121977 T ES 90121977T ES 90121977 T ES90121977 T ES 90121977T ES 2088402 T3 ES2088402 T3 ES 2088402T3
Authority
ES
Spain
Prior art keywords
sub
formula
intermediates
processes
produce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90121977T
Other languages
English (en)
Inventor
Seisaku Kumai
Masao Ohashi
Yutaka Yaginuma
Katsuhiko Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seimi Chemical Co Ltd
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Seimi Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1297609A external-priority patent/JP2595109B2/ja
Priority claimed from JP29761089A external-priority patent/JP2788512B2/ja
Application filed by Asahi Glass Co Ltd, Seimi Chemical Co Ltd filed Critical Asahi Glass Co Ltd
Application granted granted Critical
Publication of ES2088402T3 publication Critical patent/ES2088402T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/70Monocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/50Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/26Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/32Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by introduction of halogenated alkyl groups into ring compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/093Preparation of carboxylic acids or their salts, halides or anhydrides by hydrolysis of —CX3 groups, X being halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

ES UN PROCEDIMIENTO PARA LA PRODUCCION DEL ACIDO 5-FLUOROBENZOICO DE LA FORMULA (V), QUE COMPRENDE LA TRICLOROMETILACION DE UN FLUOROBENCINO DE LA FORMULA (I) PARA OBTENER UN 5-FLUOROBENZOCLORURO DE LA FORMULA (II), DESPUES REACCIONANDOLO CON AMONIACO LIQUIDO PARA OBTENER EL 5-FLUOROBENZONITRILO DE LA FORMULA (III), CUYA REACCION CON UN AGENTE DE FLUORINACION PRODUCE UN 5-FLUOROBENZONITRILO DE LA FORMULA (V) E HIDROLIZANDOLO: DONDE CADA UNA DE LAS X SUB 1, X SUB 3, Y SUB 1 E Y SUB 3 SON UN ATOMO DE HALOGENO Y CADA X SUB 2 E Y SUB 2 SON UN ATOMO DE HIDROGENO O DE HALOGENO.
ES90121977T 1989-11-17 1990-11-16 Procesos para producir acidos 5-fluorobenzoicos y sus intermedios. Expired - Lifetime ES2088402T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1297609A JP2595109B2 (ja) 1989-11-17 1989-11-17 新規フルオロベンゾトリクロリド化合物およびフルオロ安息香酸類の製造方法
JP29761089A JP2788512B2 (ja) 1989-11-17 1989-11-17 5‐フルオロベンゾニトリル類および4,5‐ジフルオロ安息香酸類の製造方法

Publications (1)

Publication Number Publication Date
ES2088402T3 true ES2088402T3 (es) 1996-08-16

Family

ID=26561182

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90121977T Expired - Lifetime ES2088402T3 (es) 1989-11-17 1990-11-16 Procesos para producir acidos 5-fluorobenzoicos y sus intermedios.

Country Status (6)

Country Link
US (2) US5241111A (es)
EP (1) EP0431373B1 (es)
KR (1) KR0177802B1 (es)
DE (1) DE69026476T2 (es)
ES (1) ES2088402T3 (es)
IE (1) IE72169B1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6906006B1 (en) 1988-11-23 2005-06-14 Bayer Aktiengesellschaft N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators
DE4238125A1 (de) * 1992-11-12 1994-05-19 Bayer Ag Substituierte Triazolinone
EP0497239A1 (de) * 1991-01-30 1992-08-05 Hoechst Aktiengesellschaft 2-Chlor-4,5-difluorbenzonitril und Verfahren zu seiner Herstellung
DE4200512C2 (de) * 1992-01-11 1994-09-15 Riedel De Haen Ag Verfahren zur Herstellung von Halogenanthranilsäuren und aromatische Bromverbindungen als Vorstufen
JPH069535A (ja) * 1992-02-26 1994-01-18 Hoechst Ag 2,4,5−トリフルオロベンゾニトリルの製造方法
DE4414841A1 (de) * 1994-04-28 1995-11-02 Bayer Ag Brom enthaltende aromatische Verbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Zwischenprodukte bei der Synthese von Wirkstoffen
DE4416329A1 (de) * 1994-05-09 1995-11-16 Hoechst Ag Substituierte 2-Chlor-3,4,5-trifluorbenzole und ein Verfahren zu ihrer Herstellung
DE19507912A1 (de) * 1995-03-07 1996-09-12 Bayer Ag Verfahren zur Herstellung von 2,4-Dichlor-5-fluorbenzonitril und 2,6-Dichlor-3-fluorbenzonitril
US5777123A (en) * 1996-03-01 1998-07-07 Merck & Co., Inc. Process for regioselective substitution of trifluorobenzoate or trifluorobenzonitrile
WO1997031891A1 (en) * 1996-03-01 1997-09-04 Merck & Co., Inc. Process for regioselective substitution of trifluorobenzoate or trifluorobenzonitrile
US7012069B2 (en) 2001-05-03 2006-03-14 Arch Development Corporation Liver X receptor agonists
US6008407A (en) * 1998-11-03 1999-12-28 Zelinsky Institute Of Organic Chemistry Method of preparing fluoroaromatic compounds
CN104649890B (zh) * 2015-02-15 2016-04-13 浙江永太科技股份有限公司 一种2,4-二氯-5-氟苯甲酰氯的制备方法
CN105669435B (zh) * 2015-02-15 2017-12-08 浙江永太科技股份有限公司 一种2,4‑二氯‑5‑氟苯甲酰氯的制备方法
CN104725221B (zh) * 2015-03-19 2016-04-27 浙江本立科技股份有限公司 一种2,4-二氯-5-氟苯甲酰氯的合成方法
CN105175245B (zh) * 2015-10-22 2017-07-18 山东国邦药业股份有限公司 一种2,4‑二氯‑5‑氟苯甲酰氯的合成方法
CN105859620B (zh) * 2016-05-05 2018-07-13 大连理工大学 一类6-三氯甲基菲啶类化合物及其制备方法和应用
CN106278860A (zh) * 2016-08-11 2017-01-04 常州工程职业技术学院 一种3‑氯‑2,4‑二氟苯甲酸的合成方法
EP3713907A4 (en) * 2019-02-15 2020-11-25 Fujian Yongjing Technology Co., Ltd NEW PROCESS FOR THE MANUFACTURING OF FLUORINE BENZENE AND FLUORINE BENZOPHENON, AND CORRESPONDING DERIVATIVES

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3187057A (en) * 1958-05-19 1965-06-01 Standard Oil Co Trichloromethyl polymethyl benzenes
DE1668068A1 (de) * 1967-12-30 1971-07-15 Hoechst Ag Verfahren zur Herstellung von Benzonitrilen
DE3142856A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoylchlorid
DE3420796A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 2,4,5-trihalogen- bzw. 2,3,4,5-tetrahalogenbenzolderivate und verfahren zu ihrer herstellung
US4791225A (en) * 1986-01-20 1988-12-13 Kyorin Pharmaceutical Co., Ltd. Halogenobenzoic acid derivatives and their preparation
JPS63188643A (ja) * 1987-01-30 1988-08-04 Central Glass Co Ltd 新規な含フツ素ベンゾフエノンおよびその製造法
JP2566976B2 (ja) * 1987-04-08 1996-12-25 日本カーバイド工業株式会社 ハロゲン置換ベンゼンカルボン酸の脱炭酸方法
CN1007150B (zh) * 1987-06-22 1990-03-14 国家医药管理局天津医药工业研究所 2,4-二氯-5-氟苯甲酸的合成
JP2577567B2 (ja) * 1987-07-07 1997-02-05 イハラケミカル工業株式会社 芳香族フッ素化合物の製造方法
DE3853654T2 (de) * 1987-08-14 1996-01-18 Asahi Glass Co Ltd Fluorierte Benzoylverbindungen.

Also Published As

Publication number Publication date
KR910009628A (ko) 1991-06-28
EP0431373A3 (en) 1992-09-02
KR0177802B1 (ko) 1999-05-15
DE69026476T2 (de) 1996-10-31
IE904085A1 (en) 1991-05-22
US5241111A (en) 1993-08-31
EP0431373A2 (en) 1991-06-12
EP0431373B1 (en) 1996-04-10
IE72169B1 (en) 1997-03-26
US5332851A (en) 1994-07-26
DE69026476D1 (de) 1996-05-15

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