ES2088402T3 - Procesos para producir acidos 5-fluorobenzoicos y sus intermedios. - Google Patents
Procesos para producir acidos 5-fluorobenzoicos y sus intermedios.Info
- Publication number
- ES2088402T3 ES2088402T3 ES90121977T ES90121977T ES2088402T3 ES 2088402 T3 ES2088402 T3 ES 2088402T3 ES 90121977 T ES90121977 T ES 90121977T ES 90121977 T ES90121977 T ES 90121977T ES 2088402 T3 ES2088402 T3 ES 2088402T3
- Authority
- ES
- Spain
- Prior art keywords
- sub
- formula
- intermediates
- processes
- produce
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
- C07C63/70—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/32—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by introduction of halogenated alkyl groups into ring compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/093—Preparation of carboxylic acids or their salts, halides or anhydrides by hydrolysis of —CX3 groups, X being halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
ES UN PROCEDIMIENTO PARA LA PRODUCCION DEL ACIDO 5-FLUOROBENZOICO DE LA FORMULA (V), QUE COMPRENDE LA TRICLOROMETILACION DE UN FLUOROBENCINO DE LA FORMULA (I) PARA OBTENER UN 5-FLUOROBENZOCLORURO DE LA FORMULA (II), DESPUES REACCIONANDOLO CON AMONIACO LIQUIDO PARA OBTENER EL 5-FLUOROBENZONITRILO DE LA FORMULA (III), CUYA REACCION CON UN AGENTE DE FLUORINACION PRODUCE UN 5-FLUOROBENZONITRILO DE LA FORMULA (V) E HIDROLIZANDOLO: DONDE CADA UNA DE LAS X SUB 1, X SUB 3, Y SUB 1 E Y SUB 3 SON UN ATOMO DE HALOGENO Y CADA X SUB 2 E Y SUB 2 SON UN ATOMO DE HIDROGENO O DE HALOGENO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP29761089A JP2788512B2 (ja) | 1989-11-17 | 1989-11-17 | 5‐フルオロベンゾニトリル類および4,5‐ジフルオロ安息香酸類の製造方法 |
JP1297609A JP2595109B2 (ja) | 1989-11-17 | 1989-11-17 | 新規フルオロベンゾトリクロリド化合物およびフルオロ安息香酸類の製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2088402T3 true ES2088402T3 (es) | 1996-08-16 |
Family
ID=26561182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90121977T Expired - Lifetime ES2088402T3 (es) | 1989-11-17 | 1990-11-16 | Procesos para producir acidos 5-fluorobenzoicos y sus intermedios. |
Country Status (6)
Country | Link |
---|---|
US (2) | US5241111A (es) |
EP (1) | EP0431373B1 (es) |
KR (1) | KR0177802B1 (es) |
DE (1) | DE69026476T2 (es) |
ES (1) | ES2088402T3 (es) |
IE (1) | IE72169B1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4238125A1 (de) * | 1992-11-12 | 1994-05-19 | Bayer Ag | Substituierte Triazolinone |
US6906006B1 (en) | 1988-11-23 | 2005-06-14 | Bayer Aktiengesellschaft | N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators |
EP0497239A1 (de) * | 1991-01-30 | 1992-08-05 | Hoechst Aktiengesellschaft | 2-Chlor-4,5-difluorbenzonitril und Verfahren zu seiner Herstellung |
DE4200512C2 (de) * | 1992-01-11 | 1994-09-15 | Riedel De Haen Ag | Verfahren zur Herstellung von Halogenanthranilsäuren und aromatische Bromverbindungen als Vorstufen |
ES2125919T3 (es) * | 1992-02-26 | 1999-03-16 | Clariant Gmbh | Procedimiento para la preparacion de 2,4,5-trifluoro-benzonitrilo. |
DE4414841A1 (de) * | 1994-04-28 | 1995-11-02 | Bayer Ag | Brom enthaltende aromatische Verbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Zwischenprodukte bei der Synthese von Wirkstoffen |
DE4416329A1 (de) * | 1994-05-09 | 1995-11-16 | Hoechst Ag | Substituierte 2-Chlor-3,4,5-trifluorbenzole und ein Verfahren zu ihrer Herstellung |
DE19507912A1 (de) * | 1995-03-07 | 1996-09-12 | Bayer Ag | Verfahren zur Herstellung von 2,4-Dichlor-5-fluorbenzonitril und 2,6-Dichlor-3-fluorbenzonitril |
US5777123A (en) * | 1996-03-01 | 1998-07-07 | Merck & Co., Inc. | Process for regioselective substitution of trifluorobenzoate or trifluorobenzonitrile |
WO1997031891A1 (en) * | 1996-03-01 | 1997-09-04 | Merck & Co., Inc. | Process for regioselective substitution of trifluorobenzoate or trifluorobenzonitrile |
US7012069B2 (en) | 2001-05-03 | 2006-03-14 | Arch Development Corporation | Liver X receptor agonists |
US6008407A (en) * | 1998-11-03 | 1999-12-28 | Zelinsky Institute Of Organic Chemistry | Method of preparing fluoroaromatic compounds |
CN104649890B (zh) * | 2015-02-15 | 2016-04-13 | 浙江永太科技股份有限公司 | 一种2,4-二氯-5-氟苯甲酰氯的制备方法 |
CN105669435B (zh) * | 2015-02-15 | 2017-12-08 | 浙江永太科技股份有限公司 | 一种2,4‑二氯‑5‑氟苯甲酰氯的制备方法 |
CN104725221B (zh) * | 2015-03-19 | 2016-04-27 | 浙江本立科技股份有限公司 | 一种2,4-二氯-5-氟苯甲酰氯的合成方法 |
CN105175245B (zh) * | 2015-10-22 | 2017-07-18 | 山东国邦药业股份有限公司 | 一种2,4‑二氯‑5‑氟苯甲酰氯的合成方法 |
CN105859620B (zh) * | 2016-05-05 | 2018-07-13 | 大连理工大学 | 一类6-三氯甲基菲啶类化合物及其制备方法和应用 |
CN106278860A (zh) * | 2016-08-11 | 2017-01-04 | 常州工程职业技术学院 | 一种3‑氯‑2,4‑二氟苯甲酸的合成方法 |
JP7353011B2 (ja) * | 2019-02-15 | 2023-09-29 | フジアン ヨンジン テクノロジー カンパニー リミテッド | フッ素化ベンゼン、フッ素化ベンゾフェノン、およびその誘導体の新しい製造方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3187057A (en) * | 1958-05-19 | 1965-06-01 | Standard Oil Co | Trichloromethyl polymethyl benzenes |
DE1668068A1 (de) * | 1967-12-30 | 1971-07-15 | Hoechst Ag | Verfahren zur Herstellung von Benzonitrilen |
DE3142856A1 (de) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoylchlorid |
DE3420796A1 (de) * | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 2,4,5-trihalogen- bzw. 2,3,4,5-tetrahalogenbenzolderivate und verfahren zu ihrer herstellung |
US4791225A (en) * | 1986-01-20 | 1988-12-13 | Kyorin Pharmaceutical Co., Ltd. | Halogenobenzoic acid derivatives and their preparation |
JPS63188643A (ja) * | 1987-01-30 | 1988-08-04 | Central Glass Co Ltd | 新規な含フツ素ベンゾフエノンおよびその製造法 |
JP2566976B2 (ja) * | 1987-04-08 | 1996-12-25 | 日本カーバイド工業株式会社 | ハロゲン置換ベンゼンカルボン酸の脱炭酸方法 |
CN1007150B (zh) * | 1987-06-22 | 1990-03-14 | 国家医药管理局天津医药工业研究所 | 2,4-二氯-5-氟苯甲酸的合成 |
JP2577567B2 (ja) * | 1987-07-07 | 1997-02-05 | イハラケミカル工業株式会社 | 芳香族フッ素化合物の製造方法 |
DE3853654T2 (de) * | 1987-08-14 | 1996-01-18 | Asahi Glass Co Ltd | Fluorierte Benzoylverbindungen. |
-
1990
- 1990-11-13 IE IE408590A patent/IE72169B1/en not_active IP Right Cessation
- 1990-11-15 US US07/614,598 patent/US5241111A/en not_active Expired - Fee Related
- 1990-11-15 KR KR1019900018495A patent/KR0177802B1/ko not_active IP Right Cessation
- 1990-11-16 ES ES90121977T patent/ES2088402T3/es not_active Expired - Lifetime
- 1990-11-16 EP EP90121977A patent/EP0431373B1/en not_active Expired - Lifetime
- 1990-11-16 DE DE69026476T patent/DE69026476T2/de not_active Expired - Fee Related
-
1993
- 1993-05-04 US US08/056,395 patent/US5332851A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0431373A2 (en) | 1991-06-12 |
KR910009628A (ko) | 1991-06-28 |
KR0177802B1 (ko) | 1999-05-15 |
IE72169B1 (en) | 1997-03-26 |
DE69026476D1 (de) | 1996-05-15 |
IE904085A1 (en) | 1991-05-22 |
US5241111A (en) | 1993-08-31 |
DE69026476T2 (de) | 1996-10-31 |
US5332851A (en) | 1994-07-26 |
EP0431373A3 (en) | 1992-09-02 |
EP0431373B1 (en) | 1996-04-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2088402T3 (es) | Procesos para producir acidos 5-fluorobenzoicos y sus intermedios. | |
IT7831388A0 (it) | Processo per la produzione di grafite flessibile. | |
DE3788248D1 (de) | Verfahren zur Herstellung von Chlor. | |
IT1102726B (it) | Poliesteri lineari utili per la fabbricazione di fibre chimiche e procedimento per la loro produzione | |
IT1154024B (it) | Derivati pridinici e procedimento per la loro produzione | |
IT1206587B (it) | Processo per la produzione di acido acetico. | |
ES2105088T3 (es) | Derivados de acidos aromaticos yodados y su utilizacion como agentes de contraste para la formacion de imagenes por rayos x. | |
ATE42550T1 (de) | Verfahren zur herstellung von tetronsaeure. | |
IT1079052B (it) | Procedimento per la produzione di acido 8 ammino 1 nafto 3,6 disolfonico | |
IT7948194A0 (it) | Procedimento per la produzione di disegni su strutture tessili | |
IT8119522A0 (it) | Procedimento per la produzione elettrolitica di idrogeno. | |
IT1098853B (it) | Processo per la produzione di 1,1,1,2-tetrafluoroetano | |
ATE49185T1 (de) | Verfahren zur herstellung von halogen-magnesium- alanat und dessen verwendung. | |
ATE1056T1 (de) | Verfahren zur herstellung von chlordioxid und gegebenenfalls chlor aus chlorwasserstoff und elektrolytisch gewonnenem alkalichlorat. | |
AR246243A1 (es) | Procedimiento de intercambio de halogeno. | |
IT7824767A0 (it) | Processo per il trattamento del butandiolo che si ottiene come condensato nella produzione di polibutilentereftalati. | |
ES555612A0 (es) | Procedimiento para la produccion de derivados del acido 7-amino-3-alcoximetil-3-cefem-4-carboxilico | |
IT1106373B (it) | Procedimento per la produzione di acido 3 4 metilendiossimandelico | |
IT1117164B (it) | Procedimento per la produzione di idrogeno mediante elettrolisi di acidi alogenici | |
IT1102607B (it) | Procedimento per la produzione di cloro e idrossido alcalino mediante elettrolisi | |
IT7920820A0 (it) | Processo per l'attivazione con acido cloridrico e cloro di un catalizzatore a base di fluoruro cromico. | |
NO20001404L (no) | Nye stereoselektive fremgangsmÕter for fremstilling av gabapentinanaloger | |
BR8705011A (pt) | Processo para producao de peroxido de hidrogenio | |
ATE32718T1 (de) | Verfahren zur herstellung von (s)glyceraldehydacetonid. | |
IT8025223A0 (it) | Procedimento per la produzione di derivati dell'acido penicillanico. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 431373 Country of ref document: ES |